Lee M. Graves

University of North Carolina at Chapel Hill

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 6%percentile

0.269Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Multi-omics signature of healthy versus unhealthy lifestyles reveals associations with diseases

Human Genomics(2025)10.1186/s40246-025-00817-7

Top 58%

0.269DataRank

Top 58%5 citations

Blake R. Rushing, Lee M. Graves, David C. Nieman, Matteo Pellegrini, Matthew Soldano +5 more

Papers

Driven by 62 papers — median percentile 21. Top paper: “Multi-omics signature of healthy versus unhealthy lifestyles reveals associations with diseases”.

Multi-omics signature of healthy versus unhealthy lifestyles reveals associations with diseases

Human Genomics(2025)10.1186/s40246-025-00817-7

Top 58%

0.269DataRank

Top 58%5 citations

Blake R. Rushing, Lee M. Graves, David C. Nieman, Matteo Pellegrini, Matthew Soldano +5 more

Enigmatic MELK: The controversy surrounding its complex role in cancer

Journal of Biological Chemistry(2020)10.1074/jbc.rev120.013433

N/A

0DataRank · unranked

36 citations

Lee M. Graves, Ian M. McDonald

Mass spectrometry–based selectivity profiling identifies a highly selective inhibitor of the kinase MELK that delays mitotic entry in cancer cells

Journal of Biological Chemistry(2020)10.1074/jbc.ra119.011083

N/A

0DataRank · unranked

30 citations

Gavin D. Grant, Michael P. East, Thomas S.K. Gilbert, Emily Wilkerson, Dennis Goldfarb +7 more

Inhibition of Lapatinib-Induced Kinome Reprogramming in ERBB2-Positive Breast Cancer by Targeting BET Family Bromodomains

UNC Libraries(2020)10.17615/vnt3-7a98

N/A

0DataRank · unranked

3 citations

Jon S. Zawistowski, Lisa A. Carey, Rachel A. Reuther, Kazuhiro Nakamura, Steven P. Angus +15 more

Angiotensin II stimulates ERK via two pathways in epithelial cells: protein kinase C suppresses a G-protein coupled receptor-EGF receptor transactivation pathway

UNC Libraries(2020)10.17615/wmhg-2f32

N/A

0DataRank · unranked

4 citations

H. Shelton Earp, Xiong Li, June Weon Lee, Lee M. Graves

Novel role of Engrailed 1 as a prosurvival transcription factor in basal-like breast cancer and engineering of interference peptides block its oncogenic function

UNC Libraries(2020)10.17615/x047-md14

N/A

0DataRank · unranked

4 citations

Pilar Blancafort, Adriana S. Beltrán, Lee M. Graves

p32 heterozygosity protects against age- and diet-induced obesity by increasing energy expenditure

UNC Libraries(2020)10.17615/tptb-nx93

N/A

0DataRank · unranked

3 citations

Yanping Zhang, Aiwen Jin, Koji Itahana, Lee M. Graves, Patrick L. Leslie +1 more

CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation

UNC Libraries(2020)10.17615/dkxr-eb15

N/A

0DataRank · unranked

2 citations

Hilary V. Clegg, Jingpu Zheng, Yi Zhang, Lee M. Graves, Taehoon Kim +6 more

Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer

UNC Libraries(2020)10.17615/ebx5-w380

N/A

0DataRank · unranked

1 citations

Deborah A. Granger, Jon S. Zawistowski, David B. Darr, Alicia A. Midland, Jerry Usary +22 more

Multicolor Monitoring of Dysregulated Protein Kinases in Chronic Myelogenous Leukemia

INDIGO (University of Illinois at Chicago)(2020)10.17615/mfx1-be60

N/A

0DataRank · unranked

1 citations

Lee M. Graves, Timothy D. Martin, David S. Lawrence, Alexei Toutchkine, Qunzhao Wang +1 more

Regulation of ENT1 expression and ENT1-dependent nucleoside transport by c-Jun N-terminal kinase

UNC Libraries(2020)10.17615/ate4-p887

N/A

0DataRank · unranked

0 citations

Shannon Z. Jones, Jing Yang, Eric I. Zimmerman, Min Huang, Andrea V. Leisewitz +1 more

The splicing activator DAZAP1 integrates splicing control into MEK/Erk-regulated cell proliferation and migration

UNC Libraries(2020)10.17615/1vz7-kx90

N/A

0DataRank · unranked

0 citations

Yi‐Hsuan Tsai, Ashutosh Tripathy, Sreerupa Ghose Roy, Rajarshi Choudhury, Lee M. Graves +1 more

The human Rad9 checkpoint protein stimulates the carbamoyl phosphate synthetase activity of the multifunctional protein CAD

UNC Libraries(2020)10.17615/5v0d-av84

N/A

0DataRank · unranked

0 citations

Lee M. Graves, Laura A. Lindsey‐Boltz, Aziz Sancar, Eric Wauson

Leflunomide Prevents Alveolar Fluid Clearance Inhibition by Respiratory Syncytial Virus

UNC Libraries(2020)10.17615/wwbt-fs61

N/A

0DataRank · unranked

0 citations

Lee M. Graves, Ian C. Davis, Xiaodong Zhao, James A. Fortenberry, Eric J. Sorscher +5 more

Molecular Pathways: Adaptive Kinome Reprogramming in Response to Targeted Inhibition of the BRAF-MEK-ERK Pathway in Cancer

UNC Libraries(2020)10.17615/cx2z-ty05

N/A

0DataRank · unranked

0 citations

Steven P. Angus, Gary L. Johnson, Jon S. Zawistowski, Lee M. Graves, Timothy J. Stuhlmiller

Determinants of sensitivity of human T-cell leukemia CCRF-CEM cells to immucillin-H

UNC Libraries(2020)10.17615/b61m-g863

N/A

0DataRank · unranked

0 citations

Min Huang, Karen Noel, Jing Yang, Beverly S. Mitchell, Jingjin Gu +3 more

Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability

UNC Libraries(2020)10.17615/395k-pt97

N/A

0DataRank · unranked

0 citations

Jeran K. Stratford, Yan Feng, Lee M. Graves, Michael B. Major, Channing J. Der +2 more

Inhibition of the mitochondrial permeability transition by protein kinase A in rat liver mitochondria and hepatocytes

UNC Libraries(2020)10.17615/c2r0-wm40

N/A

0DataRank · unranked

0 citations

John J. Lemasters, Peter Pediaditakis, Jae‐Sung Kim, Xun Zhang, Lee M. Graves +1 more

Src-Mediated Phosphorylation of the Tyrosine Phosphatase PRL-3 Is Required for PRL-3 Promotion of Rho Activation, Motility and Invasion

UNC Libraries(2020)10.17615/e0ak-yz06

N/A

0DataRank · unranked

0 citations

Adrienne D. Cox, James P. Madigan, Brian J. Dewar, James J. Fiordalisi, Lee M. Graves

Insulin-like Growth Factor-I Stimulates Shc-dependent Phosphatidylinositol 3-Kinase Activation via Grb2-associated p85 in Vascular Smooth Muscle Cells

UNC Libraries(2020)10.17615/qc8t-2f77

N/A

0DataRank · unranked

0 citations

Yashwanth Radhakrishnan, Ling Yan, Laura A. Maile, Lee M. Graves, David R. Clemmons

An Unbiased Proteomic Screen Reveals Caspase Cleavage Is Positively and Negatively Regulated by Substrate Phosphorylation

UNC Libraries(2020)10.17615/xyag-1203

N/A

0DataRank · unranked

0 citations

Shawn S.‐C. Li, Lee M. Graves, Stephanie A. Zukowski, Gilles Lajoie, James D.R. Knight +4 more

Identification of a novel point mutation in ENT1 that confers resistance to Ara-C in human T cell leukemia CCRF-CEM cells

UNC Libraries(2020)10.17615/gt20-er67

N/A

0DataRank · unranked

0 citations

Yanhong Wang, Jing Yang, Andrea V. Leisewitz, Lee M. Graves, Eric I. Zimmerman +1 more

The dynamic nature of the kinome

UNC Libraries(2020)10.17615/6bjg-5d28

N/A

0DataRank · unranked

0 citations

James S. Duncan, Martin C. Whittle, Gary L. Johnson, Lee M. Graves

Metabolic assessment of a novel chronic myelogenous leukemic cell line and an imatinib resistant subline by 1H NMR spectroscopy

UNC Libraries(2020)10.17615/sfag-te44

N/A

0DataRank · unranked

0 citations

Jeffrey M. Macdonald, Kayvan R. Keshari, Lee M. Graves, Brian J. Dewar, Rex E. Jeffries +1 more

Application of Multiplexed Kinase Inhibitor Beads to Study Kinome Adaptations in Drug-Resistant Leukemia

UNC Libraries(2020)10.17615/5gg8-3m30

N/A

0DataRank · unranked

0 citations

Nathan J. Cox, Stephen V. Frye, Gary L. Johnson, David M. Smalley, Martin C. Whittle +13 more

Kinome Profiling Identifies Druggable Targets for Novel Human Cytomegalovirus (HCMV) Antivirals

UNC Libraries(2020)10.17615/4en3-d531

N/A

0DataRank · unranked

0 citations

Laura E. Herring, Heather A. Vincent, Kyle C. Arend, Ian M. McDonald, Thomas S.K. Gilbert +7 more

Regulation of Human Cytidine Triphosphate Synthetase 2 by Phosphorylation

Carolina Digital Repository (University of North Carolina at Chapel Hill)(2020)10.17615/hmgk-9a30

N/A

0DataRank · unranked

0 citations

Lee M. Graves, Matthew J. Higgins, Karen M. Kassel, Da Ryung Au, Maria Hines

A biosensor generated via high-throughput screening quantifies cell edge Src dynamics

UNC Libraries(2020)10.17615/tbwp-gq85

N/A

0DataRank · unranked

0 citations

Eric A. Vitriol, Akash Gulyani, Dmitriy Gremyachinskiy, Tim Elston, Jianrong Wu +7 more

Activation of a Novel Calcium-dependent Protein-tyrosine Kinase: CORRELATION WITH c-Jun N-TERMINAL KINASE BUT NOT MITOGEN-ACTIVATED PROTEIN KINASE ACTIVATION

UNC Libraries(2021)10.17615/mg6r-w274

N/A

0DataRank · unranked

6 citations

Gail S. Marchetto, Benjamin F. Calvo, Deborah Hunter, Shelton Earp, H., Xiong Li +6 more

Interactions between Two Cytoskeleton-associated Tyrosine Kinases: Calcium-dependent Tyrosine Kinase and Focal Adhesion Tyrosine Kinase

UNC Libraries(2021)10.17615/jd31-kn25

N/A

0DataRank · unranked

5 citations

Xiong Li, Lee M. Graves, Ruth Dy, H. Shelton Earp, William G. Cance

Inhibition of Nucleoside Transport by p38 MAPK Inhibitors

UNC Libraries(2021)10.17615/phee-rk28

N/A

0DataRank · unranked

1 citations

Lee M. Graves, Min Huang, Jin Gu Jing, Yanhong Wang, Matthew J. Collins +1 more

Regulation of a Calcium-dependent Tyrosine Kinase in Vascular Smooth Muscle Cells by Angiotensin II and Platelet-derived Growth Factor: DEPENDENCE ON CALCIUM AND THE ACTIN CYTOSKELETON

UNC Libraries(2021)10.17615/q13m-gb33

N/A

0DataRank · unranked

2 citations

Debra M. Hunter, Yaqin He, Lee M. Graves, Xiong Li, Brian Herman +4 more

Defining the KRAS-regulated kinome in KRAS-mutant pancreatic cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.27.441678

N/A

0DataRank · unranked

0 citations

Jennifer E. Klomp, Kayla R. Snare, Devon R. Blake, Priya S. Hibshman, Zane D. Kaiser +13 more

An Intracellular Calcium Signal Activates p70 but Not p90 Ribosomal S6 Kinase in Liver Epithelial Cells

UNC Libraries(2021)10.17615/np3t-af11

N/A

0DataRank · unranked

0 citations

John M. Lambert, Deborah Hunter, Lee M. Graves, H. Shelton Earp, Yaqin He +1 more

Auto-inhibition of the Dbl Family Protein Tim by an N-terminal Helical Motif

UNC Libraries(2021)10.17615/g76g-5r61

N/A

0DataRank · unranked

0 citations

John Sondek, Antoine E. Karnoub, Jason T. Snyder, Kent L. Rossman, Marielle E. Yohe +4 more

Phosphorylation of Serine 43 Is Not Required for Inhibition of c-Raf Kinase by the cAMP-dependent Protein Kinase

UNC Libraries(2021)10.17615/8yc9-nc42

N/A

0DataRank · unranked

0 citations

Piotr Kozłowski, Sang Eun Lee, Lee M. Graves, Matthew F. Sidovar, Matthew A. Collins +1 more

Protein-tyrosine Kinase Pyk2 Mediates Endothelin-induced p38 MAPK Activation in Glomerular Mesangial Cells

UNC Libraries(2021)10.17615/c7wd-9d02

N/A

0DataRank · unranked

0 citations

Piotr Kozłowski, Andrew Philip, Lee M. Graves, А. А. Сорокин

Characterization of TR ‐107, a novel chemical activator of the human mitochondrial protease ClpP

Pharmacology Research & Perspectives(2022)10.1002/prp2.993

N/A

0DataRank · unranked

43 citations

Lucas J. Aponte‐Collazo, Joshua D. Wynn, Kristina Drizyte‐Miller, Elisa Leung, Yoshimi Endo Greer +12 more

Mitochondrial Matrix Protease ClpP Agonists Inhibit Cancer Stem Cell Function in Breast Cancer Cells by Disrupting Mitochondrial Homeostasis

Cancer Research Communications(2022)10.1158/2767-9764.crc-22-0142

N/A

0DataRank · unranked

31 citations

Lídia Hernandez, Emily M.J. Fennell, Manjari Kundu, Donna Voeller, Raj Chari +12 more

Cytomegalovirus US28 regulates cellular EphA2 to maintain viral latency

Science Advances(2022)10.1126/sciadv.add1168

N/A

0DataRank · unranked

21 citations

Benjamin A. Krishna, Laura E. Herring, Thomas S.K. Gilbert, Masatoshi Nukui, Ian J. Groves +7 more

Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization

Cell Reports(2022)10.1016/j.celrep.2022.111580

N/A

0DataRank · unranked

19 citations

Wen Yih Aw, Kathryn Hixson, T. V. Novoselova, Tammy M. Havener, Stefanie Howell +15 more

SMALL MOLECULE CLPP AGONISTS INDUCE SENESCENCE AND ALTER TRAIL-MEDIATED APOPTOTIC RESPONSE OF TRIPLE-NEGATIVE BREAST CANCER CELLS

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.11.499620

N/A

0DataRank · unranked

3 citations

Emily M.J. Fennell, Michael P. East, Thomas S.K. Gilbert, Paul R. Graves, Hani Ashamalla +5 more

Characterization of TR-107, a Novel Chemical Activator of the Human Mitochondrial Protease ClpP

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.14.480426

N/A

0DataRank · unranked

1 citations

Lucas J. Aponte‐Collazo, Joshua D. Wynn, Kristina Drizyte‐Miller, Elisa Leung, Yoshimi Endo Greer +12 more

Mitochondrial Matrix Protease ClpP Agonists inhibit Cancer Stem Cell Function in Breast Cancer Cells by Disrupting Mitochondrial Homeostasis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.18.484947

N/A

0DataRank · unranked

0 citations

Lídia Hernandez, Emily M.J. Fennell, Donna Voeller, Raj Chari, Sam Gilbert +7 more

Targeting Mitochondrial DNA Transcription by POLRMT Inhibition or Depletion as a Potential Strategy for Cancer Treatment

Biomedicines(2023)10.3390/biomedicines11061598

N/A

0DataRank · unranked

17 citations

Emily M.J. Fennell, Lee M. Graves, Sabrina Daglish

AUM302, a novel triple kinase PIM/PI3K/mTOR inhibitor, is a potent in vitro pancreatic cancer growth inhibitor

PLoS ONE(2023)10.1371/journal.pone.0294065

N/A

0DataRank · unranked

7 citations

Joseph F. LaComb, Lee M. Graves, Antonio T. Baines, Agnieszka B. Bialkowska, Komala Ingle

Metatranscriptomics analysis reveals a novel transcriptional and translational landscape during Middle East respiratory syndrome coronavirus infection

iScience(2023)10.1016/j.isci.2023.106780

N/A

0DataRank · unranked

2 citations

Wes Sanders, Amy Sims, Laura E. Herring, Natalie K. Barker, Athena Schepmoes +10 more

Supplementary Table S2 from Mitochondrial Matrix Protease ClpP Agonists Inhibit Cancer Stem Cell Function in Breast Cancer Cells by Disrupting Mitochondrial Homeostasis

(2023)10.1158/2767-9764.22545575

Top 100%

0DataRank

Top 100%0 citations

Lídia Hernandez, Emily M.J. Fennell, Manjari Kundu, Donna Voeller, Raj Chari +12 more

Targeting Mitochondrial DNA Transcription by POLRMT Inhibition or Depletion as a Potential Strategy for Cancer Treatment

UNC Libraries(2023)10.17615/wjtv-6567

N/A

0DataRank · unranked

0 citations

Emily M.J. Fennell, Sabrina Daglish, Lee M. Graves

TR-107, an Agonist of Caseinolytic Peptidase Proteolytic Subunit, Disrupts Mitochondrial Metabolism and Inhibits the Growth of Human Colorectal Cancer Cells

Molecular Cancer Therapeutics(2024)10.1158/1535-7163.mct-24-0170

N/A

0DataRank · unranked

10 citations

Joseph F. LaComb, Hetvi R. Patel, Rohan G. Reddy, John D. Haley, Lee M. Graves +3 more

Combining the constitutive TRAIL-secreting induced neural stem cell therapy with the novel anti-cancer drug TR-107 in glioblastoma

Molecular Therapy Oncology(2024)10.1016/j.omton.2024.200834

N/A

0DataRank · unranked

4 citations

Clara Mellows, Lauren Kass, Sabrina Daglish, Emily M.J. Fennell, Breanna Mann +5 more

Irreversible JNK1-JUN inhibition by JNK-IN-8 sensitizes pancreatic cancer to 5-FU/FOLFOX chemotherapy

UNC Libraries(2024)10.17615/76z2-h138

N/A

0DataRank · unranked

0 citations

Silvia G. Herrera Loeza, Yi Xu, Richard A. Moffitt, Chong Jin, Ashley B. Morrison +10 more

Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine-Resistant Pancreatic Cancer Cell Growth

UNC Libraries(2024)10.17615/jadh-1012

N/A

0DataRank · unranked

0 citations

Laura E. Herring, Alison D. Axtman, Michael P. East, Benjamin Lee, Denis O. Okumu +12 more

Mass spectrometry-based selectivity profiling identifies a highly selective inhibitor of the kinase MELK that delays mitotic entry in cancer cells

UNC Libraries(2024)10.17615/bmvq-pm20

N/A

0DataRank · unranked

0 citations

Laura E. Herring, Michael P. East, Cyrus Vaziri, Dennis Goldfarb, Emily Wilkerson +7 more

Enigmatic MELK: The controversy surrounding its complex role in cancer

UNC Libraries(2024)10.17615/ejvd-qm46

N/A

0DataRank · unranked

0 citations

Lee M. Graves, Ian M. McDonald

Application of a MYC degradation screen identifies sensitivity to CDK9 inhibitors in KRAS-mutant pancreatic cancer

UNC Libraries(2024)10.17615/90en-6z38

N/A

0DataRank · unranked

0 citations

Richard G. Hodge, Jacob E. Larson, Michael J. Emanuele, Stephen V. Frye, McKenzie P. Kline +12 more

Investigation of the Host Kinome Response to Coronavirus Infection Reveals PI3K/mTOR Inhibitors as Betacoronavirus Antivirals

UNC Libraries(2024)10.17615/xvee-qm80

N/A

0DataRank · unranked

0 citations

Yixuan J. Hou, Lee M. Graves, Ralph S. Baric, Emily A. Madden, Izabella N. Castillo +13 more

Combining the constitutive TRAIL-secreting induced neural stem cell therapy with the novel anti-cancer drug TR-107 in glioblastoma

UNC Libraries(2024)10.17615/s01d-wr92

N/A

0DataRank · unranked

0 citations

Shawn Hingtgen, Clara Mellows, Lee M. Graves, Lauren Kass, Alain Valdivia +5 more

Chemoproteomic Profiling of C. albicans for Characterization of Antifungal Kinase Inhibitors

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00097

N/A

0DataRank · unranked

6 citations

Meganathan Nandakumar, Aurora Cabrera, Bonnie Yiu, Emily Puumala, Zhongle Liu +12 more

Chemoproteomic Profiling of C. albicans for Characterization of Anti-fungal Kinase Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.10.632200

N/A

0DataRank · unranked

0 citations

Meganathan Nandakumar, Aurora Cabrera, Bonnie Yiu, Emily Puumala, Zhongle Liu +12 more

Reduction of protein phosphatase 2A (PP2A) complexity reveals cellular functions and dephosphorylation motifs of the PP2A/B′δ holoenzyme

Journal of Biological Chemistry(2020)10.1074/jbc.ra119.011270

N/A

0DataRank · unranked

21 citations

Ronald A. Merrill, Emily Wilkerson, Laura E. Herring, Lee M. Graves, Stefan Strack +1 more

Small Molecule Activators of the Mitochondrial Protease ClpP Induce Senescence in Triple-Negative Breast Cancer Cells and Sensitize Cells to the Bcl-2 Inhibitor Venetoclax

Research Square(2025)10.21203/rs.3.rs-7682325/v1

N/A

0DataRank · unranked

0 citations

Sabrina Daglish, Owen G Canterbury, Paul R. Graves, Sarah Carter, Sydney Beese +18 more

Lee M. Graves

Indexed papers

Top data-sharing exemplar

Papers