David M. Ashley

Also affiliated with Pediatric Brain Tumor Foundation

MedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 32 papers. Top paper: “Recombinant polio–rhinovirus immunotherapy for recurrent paediatric high-grade glioma: a phase 1b trial”.

Recombinant polio–rhinovirus immunotherapy for recurrent paediatric high-grade glioma: a phase 1b trial

The Lancet Child & Adolescent Health(2023)10.1016/s2352-4642(23)00031-7

N/A

1.2DataRank · unranked

48 citations

Daniel Landi, Michael C. Brown, Henry S. Friedman, Roger E. McLendon, James E. Herndon +15 more

Immunotoxin-αCD40 therapy activates innate and adaptive immunity and generates a durable antitumor response in glioblastoma models

Science Translational Medicine(2023)10.1126/scitranslmed.abn5649

N/A

0.853DataRank · unranked

30 citations

Charlotte McDowall, Luis Sánchez-Pérez, Cristina Osorio, Patrick C. Duncker, Aaron Briley +15 more

Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas

Nature Communications(2024)10.1038/s41467-024-44932-w

N/A

0.779DataRank · unranked

24 citations

Benjamin T. Whitfield, Christopher J. Pirozzi, Matthew S. Waitkus, Michael C. Brown, Michelle Bowie +22 more

The multilayered transcriptional architecture of glioblastoma ecosystems

Nature Genetics(2025)10.1038/s41588-025-02167-5

N/A

0.686DataRank · unranked

96 citations

Avishay Spitzer, Kevin C. Johnson, Luciano Garofano, Djamel Nehar-Belaid, Noam Galili Darnell +41 more

Deciphering the longitudinal trajectories of glioblastoma ecosystems by integrative single-cell genomics

Nature Genetics(2025)10.1038/s41588-025-02168-4

N/A

0.626DataRank · unranked

64 citations

Kevin C. Johnson, Masashi Nomura, Luciano Garofano, Djamel Nehar-Belaid, Noam Galili Darnell +41 more

Distribution and vulnerability of transcriptional outputs across the genome in Myc-amplified medulloblastoma cells

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.07.447394

N/A

0DataRank · unranked

1 citations

Wenzhe Wang, Meichen Dong, Kristen Roso, Paula K. Greer, Xuhui Bao +8 more

Glioma progression is shaped by genetic evolution and microenvironment interactions

Cell(2022)10.1016/j.cell.2022.04.038

N/A

0DataRank · unranked

506 citations

Kevin C. Johnson, Jan Martinek, Jason T. Huse, MacLean P. Nasrallah, Pieter Wesseling +53 more

Neuronal CaMKK2 promotes immunosuppression and checkpoint blockade resistance in glioblastoma

Nature Communications(2022)10.1038/s41467-022-34175-y

N/A

0DataRank · unranked

42 citations

Jessica Waibl Polania, Molly A. Chakraborty, Jonathan Perera, Jeremy Ratiu, Alexandra Miggelbrink +9 more

cGAS-STING pathway targeted therapies and their applications in the treatment of high-grade glioma

F1000Research(2022)10.12688/f1000research.125163.1

N/A

0DataRank · unranked

16 citations

Hinda Najem, Akanksha Mahajan, Peng Zhang, Justin Low, Alexander H. Stegh +5 more

A phase 1 trial of D2C7-it in combination with an Fc-engineered anti-CD40 monoclonal antibody (2141-V11) administered intratumorally via convection-enhanced delivery for adult patients with recurrent malignant glioma (MG).

Journal of Clinical Oncology(2022)10.1200/jco.2022.40.16_suppl.e14015

N/A

0DataRank · unranked

10 citations

Vidyalakshmi Chandramohan, Daniel Landi, Margaret Johnson, Mustafa Khasraw, Katherine B. Peters +12 more

Cancer-associated SMARCAL1 loss-of-function mutations promote alternative lengthening of telomeres and tumorigenesis in telomerase-negative glioblastoma cells

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.19.507319

N/A

0DataRank · unranked

0 citations

Cheng Xu, Bill H. Diplas, Alexandrea Brown, Laura M. Strickland, Jinjie Ling +6 more

Correcting the drug development paradigm for glioblastoma requires serial tissue sampling

Nature Medicine(2023)10.1038/s41591-023-02464-8

N/A

0DataRank · unranked

54 citations

Kelly Hotchkiss, Ian F. Parney, John de Groot, Solmaz Sahebjam, Nader Sanai +31 more

Cancer-associated SMARCAL1 loss-of-function mutations promote alternative lengthening of telomeres and tumorigenesis in telomerase-negative glioblastoma cells

Neuro-Oncology(2023)10.1093/neuonc/noad022

N/A

0DataRank · unranked

27 citations

Cheng Xu, Bill H. Diplas, Alexandrea Brown, Laura M. Strickland, Haipei Yao +7 more

Repurposing Clemastine to Target Glioblastoma Cell Stemness

Cancers(2023)10.3390/cancers15184619

N/A

0DataRank · unranked

5 citations

Rui Yang, Heng Liu, Wenzhe Wang, Xiao Song, Bo Hu +12 more

Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.20.537594

N/A

0DataRank · unranked

1 citations

Benjamin T. Whitfield, Christopher J. Pirozzi, Matthew S. Waitkus, Michael C. Brown, Michelle Bowie +22 more

Gene expression analysis suggests immunosuppressive roles of endolysosomes in glioblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.31.555740

N/A

0DataRank · unranked

1 citations

Haipei Yao, Qing Yang, Christopher J. Pirozzi, Vidya Chandramohan, David M. Ashley +2 more

Data from A Modified Nucleoside 6-Thio-2′-Deoxyguanosine Exhibits Antitumor Activity in Gliomas

(2023)10.1158/1078-0432.c.6531102.v1

N/A

0DataRank · unranked

0 citations

Shiyou Wei, Milan R. Savani, Xiang Lin, Kuang Du, Ilgen Mender +33 more

Distinct molecular features and potential therapeutic strategies for spinal cord gliomas.

Journal of Clinical Oncology(2023)10.1200/jco.2023.41.16_suppl.2056

N/A

0DataRank · unranked

0 citations

Joanne Xiu, Patricia Pittman, Edith Yuan, Tania Vartanians, Phillip Walker +15 more

Understanding and therapeutically exploiting cGAS/STING signaling in glioblastoma

Journal of Clinical Investigation(2024)10.1172/jci163452

N/A

0DataRank · unranked

68 citations

Michael C. Brown, Zachary J. Reitman, Joshua D. Bernstock, James M. Markert, Gregory K. Friedman +4 more

A brave new framework for glioma drug development

The Lancet Oncology(2024)10.1016/s1470-2045(24)00190-6

N/A

0DataRank · unranked

26 citations

Philipp Karschnia, Karisa C. Schreck, Marjolein Geurts, Timothy F. Cloughesy, Jason T. Huse +34 more

Mechanisms of telomere maintenance and associated therapeutic vulnerabilities in malignant gliomas

Neuro-Oncology(2024)10.1093/neuonc/noae016

N/A

0DataRank · unranked

15 citations

Elise N. Erman, Zachary J. Reitman, David M. Ashley, Matthew S. Waitkus

Taking the STING out of radiotherapy: STING checkpoints mediate radiation resistance

Journal of Clinical Investigation(2024)10.1172/jci186547

N/A

0DataRank · unranked

6 citations

Justin Low, Michelle Bowie, David M. Ashley, Michael C. Brown

Gene expression analysis suggests immunosuppressive roles of endolysosomes in glioblastoma

PLoS ONE(2024)10.1371/journal.pone.0299820

N/A

0DataRank · unranked

3 citations

Haipei Yao, Qing Yang, Christopher J. Pirozzi, Vidya Chandramohan, David M. Ashley +2 more

Elucidating cellular response to treatment with viral immunotherapies in pediatric high-grade glioma and medulloblastoma

Translational Oncology(2024)10.1016/j.tranon.2024.101875

N/A

0DataRank · unranked

6 citations

Kyung‐Don Kang, Kevin Stevenson, Hengshan Zhang, Matthias Gromeier, David M. Ashley +3 more

Resilience and Vulnerabilities of Tumor Cells under Purine Shortage Stress

Clinical Cancer Research(2025)10.1158/1078-0432.ccr-25-1667

N/A

0DataRank · unranked

6 citations

Chen Jin, Cheng Su, David Moon, Michael A. Sun, Hong Zhang +12 more

Disruption of ataxia telangiectasia–mutated kinase enhances radiation therapy efficacy in spatially directed diffuse midline glioma models

Journal of Clinical Investigation(2025)10.1172/jci179395

N/A

0DataRank · unranked

5 citations

Vennesa Valentine, Spencer M. Maingi, Sophie R. Wu, Harrison Q. Liu, Michael Aksu +24 more

Phase I trial of D2C7 immunotoxin (D2C7-IT) administered intratumorally via convection-enhanced delivery (CED) for recurrent malignant glioma (MG).

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.2566

N/A

0DataRank · unranked

5 citations

Dina Randazzo, Vidyalakshmi Chandramohan, Katherine B. Peters, Margaret Johnson, Stevie Threatt +10 more

Beyond DNA damage response: Immunomodulatory attributes of CHEK2 in solid tumors

Oncotarget(2025)10.18632/oncotarget.28740

N/A

0DataRank · unranked

5 citations

Heba Ali, Vivekanudeep Karri, Justin Low, David M. Ashley, Amy B. Heimberger +4 more

Establishment of patient-derived organoid models of lower-grade glioma

Neuro-Oncology(2021)10.1093/neuonc/noab273

N/A

0DataRank · unranked

99 citations

Cylaina Bird, Joseph Buehler, Lauren C. Gattie, Milan R. Savani, Alex Sternisha +14 more

Systematic review of combinations of targeted or immunotherapy in advanced solid tumors

Journal for ImmunoTherapy of Cancer(2021)10.1136/jitc-2021-002459

N/A

0DataRank · unranked

83 citations

Stephen Bagley, Patrick Y. Wen, Michael Lim, Michael Platten, Howard Colman +16 more

A Modified Nucleoside 6-Thio-2′-Deoxyguanosine Exhibits Antitumor Activity in Gliomas

Clinical Cancer Research(2021)10.1158/1078-0432.ccr-21-0374

N/A

0DataRank · unranked

30 citations

Shiyou Wei, Milan R. Savani, Xiang Lin, Kuang Du, Ilgen Mender +33 more

Salting the Soil: Targeting the Microenvironment of Brain Metastases

Molecular Cancer Therapeutics(2021)10.1158/1535-7163.mct-20-0579

N/A

0DataRank · unranked

27 citations

Aaron C. Tan, Carey K. Anders, Ann Marie Pendergast, Dorothy A. Sipkins, David M. Ashley +3 more