Samuel F. Bakhoum

Also affiliated with Acorda Therapeutics (United States), Cidara Therapeutics (United States)

Biochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

5.3Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A molecular single-cell lung atlas of lethal COVID-19

Nature(2021)10.1038/s41586-021-03569-1

Top 4%

5.3DataRank

Top 4%737 citations

Jana Biermann, Huachao Huang, Yiping Wang, Ajay Nair, Somnath Tagore +39 more

Papers

Driven by 49 papers — median percentile 96. Top paper: “Regenerative lineages and immune-mediated pruning in lung cancer metastasis”.

Regenerative lineages and immune-mediated pruning in lung cancer metastasis

Nature Medicine(2020)10.1038/s41591-019-0750-6

N/A

9.1DataRank · unranked

504 citations

Jing Hu, Nathaniel R. Campbell, Samuel F. Bakhoum, Manu Setty, Vincent‐Philippe Lavallée +14 more

Pervasive chromosomal instability and karyotype order in tumour evolution

Nature(2020)10.1038/s41586-020-2698-6

N/A

7.1DataRank · unranked

405 citations

Emilia L. Lim, Marina Petković, Sergi Elizalde, Nicolai J. Birkbak, Gareth A. Wilson +50 more

Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis

Cancer Discovery(2020)10.1158/2159-8290.cd-20-0387

N/A

6.9DataRank · unranked

289 citations

Mercedes A. Duran Paez, Ninjit Dhanota, Walid K. Chatila, Sarah E. Bettigole, John Y. H. Kwon +36 more

A molecular single-cell lung atlas of lethal COVID-19

Nature(2021)10.1038/s41586-021-03569-1

Top 4%

5.3DataRank

Top 4%737 citations

Jana Biermann, Huachao Huang, Yiping Wang, Ajay Nair, Somnath Tagore +39 more

The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance

Nature Genetics(2023)10.1038/s41588-023-01592-8

N/A

1.9DataRank · unranked

88 citations

Philippe Gui, Manasi K. Mayekar, Emily K. Law, Oriol Pich, Chris Bailey +80 more

The CD58-CD2 axis is co-regulated with PD-L1 via CMTM6 and shapes anti-tumor immunity

Cancer Cell(2023)10.1016/j.ccell.2023.05.014

N/A

1.8DataRank · unranked

96 citations

Johannes C. Melms, Meri Rogava, Chris J. Frangieh, Joanna Poźniak, Shivem B. Shah +28 more

Micronuclear collapse from oxidative damage

Science(2024)10.1126/science.adj8691

N/A

1.3DataRank · unranked

71 citations

Yanyang Chen, Albert S. Agustinus, Alice Mazzagatti, Mercedes A. Duran Paez, Matthew Deyell +27 more

Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients

Cell(2022)10.1016/j.cell.2022.01.003

N/A

0.973DataRank · unranked

654 citations

Christopher J. Fong, Anisha Luthra, Shaleigh Smith, Renzo G. DiNatale, Subhiksha Nandakumar +70 more

Non-cell-autonomous cancer progression from chromosomal instability

Nature(2023)10.1038/s41586-023-06464-z

N/A

0.852DataRank · unranked

292 citations

Melissa J. Hubisz, Ethan M. Earlie, Mercedes A. Duran Paez, Christy Hong, Austin Varela +20 more

Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation

Nature Cancer(2024)10.1038/s43018-023-00704-x

N/A

0.464DataRank · unranked

21 citations

Tyler J. Aprati, Wei-Yu Chi, Johannes C. Melms, Clemens Hug, Stephanie H. Davis +40 more

Validation of Patient-Reported Outcomes in Patients With Nonmetastatic Breast Cancer Receiving Comprehensive Nodal Irradiation in the RadComp Trial

International Journal of Radiation Oncology*Biology*Physics(2024)10.1016/j.ijrobp.2024.03.020

N/A

0.224DataRank · unranked

3 citations

Stephanie L. Pugh, Hien L. Lu, Alyssa Vela, Erin F. Gillespie, Elizabeth Nichols +95 more

Large-scale copy number alterations are enriched for synthetic viability in BRCA1/BRCA2 tumors

Genome Medicine(2024)10.1186/s13073-024-01371-y

N/A

0.208DataRank · unranked

3 citations

Xin Pei, Ardijana Novaj, Jeremy Setton, Daniel Bronder, Fatemeh Derakhshan +15 more

Limited Environmental Serine Confers Sensitivity to PHGDH Inhibition in Brain Metastasis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.03.974980

N/A

0.104DataRank · unranked

1 citations

Eugenie Kim, Victoria Osorio-Vasquez, Sophia Doll, Sophia Bustraan, Alba Luengo +30 more

Intra-tumor heterogeneity, turnover rate and karyotype space shape susceptibility to missegregation-induced extinction

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.03.466486

N/A

0DataRank · unranked

2 citations

Richard J. Beck, Xiaoqing Yu, Thomas Veith, Samuel F. Bakhoum, Philipp M. Altrock +2 more

Ovarian cancer mutational processes drive site-specific immune evasion

Nature(2022)10.1038/s41586-022-05496-1

N/A

0DataRank · unranked

314 citations

Florian Uhlitz, Nicholas Ceglia, Jamie Lim, Michelle Wu, Neeman Mohibullah +56 more

Dissecting the treatment-naive ecosystem of human melanoma brain metastasis

Cell(2022)10.1016/j.cell.2022.06.007

N/A

0DataRank · unranked

216 citations

Johannes C. Melms, Amit Dipak Amin, Yiping Wang, Lindsay Caprio, Alcida Karz +54 more

Chromosomal instability as a source of genomic plasticity

Current Opinion in Genetics & Development(2022)10.1016/j.gde.2022.101913

N/A

0DataRank · unranked

40 citations

Samuel F. Bakhoum, Duaa H. Al-Rawi

The pleiotropic roles of cGAS–STING signaling in the tumor microenvironment

Journal of Molecular Cell Biology(2022)10.1093/jmcb/mjac019

N/A

0DataRank · unranked

28 citations

Samuel F. Bakhoum, Jun Li

Innate immune signaling drives late cardiac toxicity following DNA-damaging cancer therapies

The Journal of Experimental Medicine(2022)10.1084/jem.20220809

N/A

0DataRank · unranked

28 citations

Suchit H. Patel, Valery Chávez, Zachary Moore, Mutayyaba Adnan, Melody Di Bona +13 more

cGAS–STING and the deadly CIN: how chronic inflammation represents a therapeutic vulnerability in chromosomally unstable cancers

Trends in cancer(2022)10.1016/j.trecan.2022.07.006

N/A

0DataRank · unranked

8 citations

Samuel F. Bakhoum

APOBEC3 as a driver of genetic intratumor heterogeneity

Molecular & Cellular Oncology(2022)10.1080/23723556.2021.2014734

N/A

0DataRank · unranked

3 citations

Mihaela Angelova, Jiřina Bártková, Samuel F. Bakhoum, Jiří Bártek, Nnennaya Kanu +2 more

Biochemical, genomic, and epigenomic profiling of isolated cancer cell lines’ micronuclei

Methods in cell biology(2022)10.1016/bs.mcb.2022.07.001

N/A

0DataRank · unranked

3 citations

Samuel F. Bakhoum, Albert S. Agustinus

The CD58:CD2 axis is co-regulated with PD-L1 via CMTM6 and governs anti-tumor immunity

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.21.485049

N/A

0DataRank · unranked

10 citations

Johannes C. Melms, Meri Rogava, Chris J. Frangieh, Shivem B. Shah, Zachary Walsh +21 more

Mitotic clustering of pulverized chromosomes from micronuclei

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.19.500697

N/A

0DataRank · unranked

7 citations

Jose Espejo Valle-Inclán, Alice Mazzagatti, Qing Hu, Elizabeth G. Maurais, Alison Guyer +8 more

Epigenetic dysregulation from chromosomal transit in micronuclei

Nature(2023)10.1038/s41586-023-06084-7

N/A

0DataRank · unranked

118 citations

Duaa H. Al-Rawi, Bhargavi Dameracharla, Ramya Raviram, Bailey S.C.L. Jones, Stephanie Stransky +27 more

Mitotic clustering of pulverized chromosomes from micronuclei

Nature(2023)10.1038/s41586-023-05974-0

N/A

0DataRank · unranked

81 citations

Qing Hu, Alice Mazzagatti, Jose Espejo Valle-Inclán, Elizabeth G. Maurais, Rashmi Dahiya +9 more

Intra-tumor heterogeneity, turnover rate and karyotype space shape susceptibility to missegregation-induced extinction

PLoS Computational Biology(2023)10.1371/journal.pcbi.1010815

N/A

0DataRank · unranked

10 citations

Richard J. Beck, Xiaoqing Yu, Thomas Veith, Samuel F. Bakhoum, Philipp M. Altrock +2 more

Chromosomal instability as a driver of cancer progression

Nature Reviews Genetics(2024)10.1038/s41576-024-00761-7

N/A

0DataRank · unranked

104 citations

Albert S. Agustinus, Jun Li, Melody DiBona, Samuel F. Bakhoum, Xuelan Chen

A p62-dependent rheostat dictates micronuclei catastrophe and chromosome rearrangements

Science(2024)10.1126/science.adj7446

N/A

0DataRank · unranked

46 citations

Simone Scorzoni, Sara Cordone, Alice Mazzagatti, Galina V. Beznoussenko, Amanda Gunn +24 more

Intratumoral TREX1 Induction Promotes Immune Evasion by Limiting Type I IFN

Cancer Immunology Research(2024)10.1158/2326-6066.cir-23-1093

N/A

0DataRank · unranked

39 citations

Alexandra Dananberg, Josefine Striepen, James H. Hickling, Abraham Shim, Yanyang Chen +6 more

Targeting chromosomal instability in patients with cancer

Nature Reviews Clinical Oncology(2024)10.1038/s41571-024-00923-w

N/A

0DataRank · unranked

37 citations

Emanuele Lettera, Jun Li, Melody DiBona, Samuel F. Bakhoum, Duaa H. Al-Rawi

Molecular and Clinical Determinants of Acquired Resistance and Treatment Duration for Targeted Therapies in Colorectal Cancer

Clinical Cancer Research(2024)10.1158/1078-0432.ccr-23-4005

N/A

0DataRank · unranked

9 citations

Fergus Keane, Henry Walch, Joanne F. Chou, Jenna Sinopoli, Silvia Palladino +13 more

A new microscopy pipeline for studying the initial stages of nuclear and micronuclear rupture and repair

Frontiers in Cell and Developmental Biology(2024)10.3389/fcell.2024.1475095

N/A

0DataRank · unranked

1 citations

Samuel F. Bakhoum, Melody Di Bona

Ongoing genome doubling promotes evolvability and immune dysregulation in ovarian cancer

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.11.602772

N/A

0DataRank · unranked

11 citations

Ignacio Vázquez-Garćıa, Matthew Myers, Matthew Zatzman, Duaa H. Al-Rawi, Adam C. Weiner +52 more

Ongoing genome doubling shapes evolvability and immunity in ovarian cancer

Nature(2025)10.1038/s41586-025-09240-3

N/A

0DataRank · unranked

39 citations

Ignacio Vázquez-Garćıa, Matthew Myers, Duaa H. Al-Rawi, Matthew Zatzman, Adam C. Weiner +53 more

Epigenetic Regulation of Chromosomal Instability by EZH2 Methyltransferase

Cancer Discovery(2025)10.1158/2159-8290.cd-25-0947

N/A

0DataRank · unranked

4 citations

Albert S. Agustinus, Shira Yomtoubian, Cem Meydan, Dylan McNally, Liron Yoffe +16 more

Energetics of whole genome doubling and genomic instability

Cancer Letters(2025)10.1016/j.canlet.2025.217878

N/A

0DataRank · unranked

0 citations

Vural Tagal, Samirkumar B. Amin, Samuel F. Bakhoum, Carlo C. Maley, Roel G.W. Verhaak +3 more

Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition

Cancer Discovery(2020)10.1158/2159-8290.cd-19-1228

N/A

0DataRank · unranked

287 citations

Eugenie Kim, Victoria Osorio-Vasquez, Sophia Doll, Sophia Bustraan, Roger J. Liang +35 more

Breast Radiation Therapy Under COVID-19 Pandemic Resource Constraints—Approaches to Defer or Shorten Treatment From a Comprehensive Cancer Center in the United States

Advances in Radiation Oncology(2020)10.1016/j.adro.2020.03.013

N/A

0DataRank · unranked

106 citations

Erin F. Gillespie, Linda Hong, Amy Xu, Samuel F. Bakhoum, John Cuaron +6 more

Re-awakening Innate Immune Signaling in Cancer: The Development of Highly Potent ENPP1 Inhibitors

Cell chemical biology(2020)10.1016/j.chembiol.2020.11.001

N/A

0DataRank · unranked

14 citations

Samuel F. Bakhoum, Derek A. Cogan

Morphology-Predicted Large-Scale Transition Number in Circulating Tumor Cells Identifies a Chromosomal Instability Biomarker Associated with Poor Outcome in Castration-Resistant Prostate Cancer

Cancer Research(2020)10.1158/0008-5472.can-20-1216

N/A

0DataRank · unranked

42 citations

Jimmy L. Zhao, Adam Jendrisak, Emily Carbone, Ethan Barnett, Melanie Hullings +11 more

A CINful way to overcome addiction: how chromosomal instability enables cancer to overcome its oncogene addiction

EMBO Molecular Medicine(2020)10.15252/emmm.202012017

N/A

0DataRank · unranked

7 citations

Samuel F. Bakhoum, Daniel Bronder

Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution

Cancer Discovery(2021)10.1158/2159-8290.cd-20-0725

N/A

0DataRank · unranked

143 citations

Mihaela Angelova, Clare Puttick, Hao-Ran Zhai, Deborah R. Caswell, Wei-Ting Lu +41 more

The Evolution of STING Signaling and Its Involvement in Cancer

Trends in Biochemical Sciences(2021)10.1016/j.tibs.2020.12.010

N/A

0DataRank · unranked

74 citations

Samuel F. Bakhoum, Nimi Vashi

Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression

Nature Communications(2021)10.1038/s41467-021-25529-z

N/A

0DataRank · unranked

61 citations

Jasmine H. Francis, Albert S. Agustinus, Ethan M. Earlie, Melody Di Bona, David H. Abramson +9 more

Deep learning predicts chromosomal instability from histopathology images

iScience(2021)10.1016/j.isci.2021.102394

N/A

0DataRank · unranked

45 citations

Akanksha Verma, Uska Naveed, Samuel F. Bakhoum, Pegah Khosravi, Olivier Elemento +1 more

The clinical and molecular significance associated with STING signaling in breast cancer

npj Breast Cancer(2021)10.1038/s41523-021-00283-z

N/A

0DataRank · unranked

39 citations

Matthew P. Humphries, Elaine S. Gilmore, Fatima Abdullahi Sidi, Victoria Bingham, Su Phyu +11 more

APOBEC3A drives STING-dependent metastasis

Nature Cancer(2021)10.1038/s43018-021-00286-6

N/A

0DataRank · unranked

3 citations

Samuel F. Bakhoum

Co-targeting TGF-β and PD-L1 with radiation therapy: The Goldilocks principle

Cell Reports Medicine(2021)10.1016/j.xcrm.2021.100406

N/A

0DataRank · unranked

2 citations

Charles M. Rudin, Samuel F. Bakhoum

Samuel F. Bakhoum

Indexed papers

Top data-sharing exemplar

Papers