Li Yan

Roswell Park Comprehensive Cancer Center

Also affiliated with Duke University, Beijing University of Chinese Medicine, Wenzhou Medical University, Zhoushan Hospital, The Affiliated Yongchuan Hospital of Chongqing Medical University, Mayo Clinic in Florida, Beijing Hospital of Traditional Chinese Medicine, Shandong First Medical University, Chongqing Medical University

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.885Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

An epigenome-wide analysis of socioeconomic position and tumor DNA methylation in breast cancer patients

Clinical Epigenetics(2023)10.1186/s13148-023-01470-4

Top 37%

0.526DataRank

Top 37%8 citations

Mark D. Long, Sirinapa Sribenja, Sung Jun, Li Yan, Qiang Hu +11 more

Papers

Driven by 56 papers — median percentile 57. Top paper: “An epigenome-wide analysis of socioeconomic position and tumor DNA methylation in breast cancer patients”.

An epigenome-wide analysis of socioeconomic position and tumor DNA methylation in breast cancer patients

Clinical Epigenetics(2023)10.1186/s13148-023-01470-4

Top 37%

0.526DataRank

Top 37%8 citations

Mark D. Long, Sirinapa Sribenja, Sung Jun, Li Yan, Qiang Hu +11 more

Association of allograft rejection response score with biological cancer aggressiveness and with better survival in triple-negative breast cancer (TNBC).

Journal of Clinical Oncology(2021)10.1200/jco.2021.39.15_suppl.561

Top 49%

0.359DataRank

Top 49%5 citations

Lan Le, Fernando A. Angarita, Yoshihisa Tokumaru, Li Yan, Ryusei Matsuyama +3 more

mTOR inhibition modulates vaccine-induced immune responses to generate memory T cells in patients with solid tumors

Journal for ImmunoTherapy of Cancer(2025)10.1136/jitc-2024-010408

N/A

0.353DataRank · unranked

7 citations

Junko Matsuzaki, Mark D. Long, Spencer R. Rosario, Thinle Chodon, Takemasa Tsuji +14 more

The E2F Pathway Score as a Predictive Biomarker of Response to Neoadjuvant Therapy in ER+/HER2− Breast Cancer

Cells(2020)10.3390/cells9071643

N/A

0DataRank · unranked

134 citations

Hideo Takahashi, Yoshihisa Tokumaru, Li Yan, Omar M. Rashid, Masayuki Nagahashi +4 more

Abundance of Regulatory T Cell (Treg) as a Predictive Biomarker for Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer

Cancers(2020)10.3390/cancers12103038

N/A

0DataRank · unranked

106 citations

Mariko Asaoka, Yoshihisa Tokumaru, Fernando A. Angarita, Li Yan, Ryusei Matsuyama +5 more

Plasmacytoid Dendritic Cell (pDC) Infiltration Correlate with Tumor Infiltrating Lymphocytes, Cancer Immunity, and Better Survival in Triple Negative Breast Cancer (TNBC) More Strongly than Conventional Dendritic Cell (cDC)

Cancers(2020)10.3390/cancers12113342

N/A

0DataRank · unranked

101 citations

Stephanie Newman, Yoshihisa Tokumaru, Li Yan, Ryusei Matsuyama, Paweł Kaliński +3 more

Intra-Tumoral Angiogenesis Is Associated with Inflammation, Immune Reaction and Metastatic Recurrence in Breast Cancer

International Journal of Molecular Sciences(2020)10.3390/ijms21186708

N/A

0DataRank · unranked

92 citations

Stephanie Newman, Yoshihisa Tokumaru, Li Yan, Ryusei Matsuyama, Itaru Endo +3 more

Biologically Aggressive Phenotype and Anti-cancer Immunity Counterbalance in Breast Cancer with High Mutation Rate

Scientific Reports(2020)10.1038/s41598-020-58995-4

N/A

0DataRank · unranked

87 citations

Mariko Asaoka, Li Yan, Omar M. Rashid, Masanori Oshi, Takashi Ishikawa +3 more

Immune Cytolytic Activity for Comprehensive Understanding of Immune Landscape in Hepatocellular Carcinoma

Cancers(2020)10.3390/cancers12051221

N/A

0DataRank · unranked

76 citations

Tsutomu Kawaguchi, Li Yan, Xuan Peng, Qianya Qi, Luc G.T. Morris +5 more

Inflammation Is Associated with Worse Outcome in the Whole Cohort but with Better Outcome in Triple‐Negative Subtype of Breast Cancer Patients

Journal of Immunology Research(2020)10.1155/2020/5618786

N/A

0DataRank · unranked

69 citations

Stephanie Newman, Yoshihisa Tokumaru, Li Yan, Ryusei Matsuyama, Itaru Endo +2 more

Intratumoral Adipocyte-High Breast Cancer Enrich for Metastatic and Inflammation-Related Pathways but Associated with Less Cancer Cell Proliferation

International Journal of Molecular Sciences(2020)10.3390/ijms21165744

N/A

0DataRank · unranked

56 citations

Masanori Oshi, Eriko Katsuta, Li Yan, Jing Huang, Masayuki Nagahashi +5 more

Degree of Early Estrogen Response Predict Survival after Endocrine Therapy in Primary and Metastatic ER-Positive Breast Cancer

Cancers(2020)10.3390/cancers12123557

N/A

0DataRank · unranked

56 citations

Yoshihisa Tokumaru, Fernando A. Angarita, Li Yan, Ryusei Matsuyama, Itaru Endo +2 more

A Novel 4-gene Score to Predict Survival, Distant Metastasis and Response to Neoadjuvant Therapy in Breast Cancer

Cancers(2020)10.3390/cancers12051148

N/A

0DataRank · unranked

52 citations

Eriko Katsuta, Li Yan, John M.L. Ebos, Omar M. Rashid, Ryusei Matsuyama +3 more

ITPKC as a Prognostic and Predictive Biomarker of Neoadjuvant Chemotherapy for Triple Negative Breast Cancer

Cancers(2020)10.3390/cancers12102758

N/A

0DataRank · unranked

46 citations

Stephanie Newman, Vijayashree Murthy, Yoshihisa Tokumaru, Li Yan, Ryusei Matsuyama +3 more

High Expression of NRF2 Is Associated with Increased Tumor-Infiltrating Lymphocytes and Cancer Immunity in ER-Positive/HER2-Negative Breast Cancer

Cancers(2020)10.3390/cancers12123856

N/A

0DataRank · unranked

42 citations

Fernando A. Angarita, Yoshihisa Tokumaru, Li Yan, Ryusei Matsuyama, Itaru Endo +2 more

High G2M Pathway Score Pancreatic Cancer is Associated with Worse Survival, Particularly after Margin-Positive (R1 or R2) Resection

Cancers(2020)10.3390/cancers12102871

N/A

0DataRank · unranked

63 citations

Stephanie Newman, Yoshihisa Tokumaru, Li Yan, Ryusei Matsuyama, Itaru Endo +3 more

Molecular Biological Features of Nottingham Histological Grade 3 Breast Cancers

Annals of Surgical Oncology(2020)10.1245/s10434-020-08608-1

N/A

0DataRank · unranked

54 citations

Masanori Oshi, Mariko Asaoka, Li Yan, Itaru Endo, Kazuaki Takabe +1 more

The Impact of Immunofunctional Phenotyping on the Malfunction of the Cancer Immunity Cycle in Breast Cancer

Cancers(2020)10.3390/cancers13010110

N/A

0DataRank · unranked

17 citations

Toshihiko Torigoe, Li Yan, Jing Huang, Hiroko Yamashita, Kazuaki Takabe +1 more

Germline variation in the insulin-like growth factor pathway and risk of Barrett’s esophagus and esophageal adenocarcinoma

Carcinogenesis(2020)10.1093/carcin/bgaa132

N/A

0DataRank · unranked

14 citations

Jianhong Chen, Li Yan, Qianchuan He, Puya Gharahkhani, Lynn Onstad +68 more

Regulation of hypoxia‐inducible factor functions in the nucleus by sphingosine‐1‐phosphate

The FASEB Journal(2020)10.1096/fj.201901734rr

N/A

0DataRank · unranked

40 citations

Aparna Maiti, Pan Xu, Qianya Qi, Tsutomu Kawaguchi, Maiko Okano +4 more

Transcriptomic Profile of Lymphovascular Invasion, a Known Risk Factor of Pancreatic Ductal Adenocarcinoma Metastasis

Cancers(2020)10.3390/cancers12082033

N/A

0DataRank · unranked

39 citations

Eriko Katsuta, Li Yan, Yoshihisa Tokumaru, Matthew H. G. Katz, Kazuaki Takabe +1 more

A Novel Four-Gene Score to Predict Pathologically Complete (R0) Resection and Survival in Pancreatic Cancer

Cancers(2020)10.3390/cancers12123635

N/A

0DataRank · unranked

30 citations

Yoshihisa Tokumaru, Ankit Patel, Li Yan, Ryusei Matsuyama, Itaru Endo +3 more

Stem Cell Therapy of Myocardial Infarction: A Promising Opportunity in Bioengineering

Advanced Therapeutics(2020)10.1002/adtp.201900182

N/A

0DataRank · unranked

27 citations

Li Yan, James G. Shamul, Maxwell Hakun, Xiaoming He, Bin Jiang

Functional hotness score based on three genes predicts long-term survival of triple-negative breast cancer independent from tumor mutational burden.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.e12583

N/A

0DataRank · unranked

0 citations

Li Yan, Mateusz Opyrchal, Paweł Kaliński, Kazuaki Takabe, Eriko Katsuta

Immunogenicity and transcriptomic biology in Nottingham histologic grade 3 breast cancer.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.e12563

N/A

0DataRank · unranked

0 citations

Masanori Oshi, Mariko Asaoka, Li Yan, Kazuaki Takabe, Hideo Takahashi

Enhanced DNA Repair Pathway is Associated with Cell Proliferation and Worse Survival in Hepatocellular Carcinoma (HCC)

Cancers(2021)10.3390/cancers13020323

N/A

0DataRank · unranked

59 citations

Tae Hee Kim, Yoshihisa Tokumaru, Li Yan, Ryusei Matsuyama, Itaru Endo +3 more

Adipogenesis in triple-negative breast cancer is associated with unfavorable tumor immune microenvironment and with worse survival

Scientific Reports(2021)10.1038/s41598-021-91897-7

N/A

0DataRank · unranked

54 citations

Yoshihisa Tokumaru, Fernando A. Angarita, Lan Lee, Li Yan, Ryusei Matsuyama +3 more

Annexin A1 Expression Is Associated with Epithelial–Mesenchymal Transition (EMT), Cell Proliferation, Prognosis, and Drug Response in Pancreatic Cancer

Cells(2021)10.3390/cells10030653

N/A

0DataRank · unranked

53 citations

Yoshihisa Tokumaru, Swagoto Mukhopadhyay, Li Yan, Ryusei Matsuyama, Itaru Endo +2 more

The Unfolded Protein Response Is Associated with Cancer Proliferation and Worse Survival in Hepatocellular Carcinoma

Cancers(2021)10.3390/cancers13174443

N/A

0DataRank · unranked

34 citations

Masanori Oshi, Li Yan, Ryusei Matsuyama, Itaru Endo, Kazuaki Takabe +1 more

Abundance of Microvascular Endothelial Cells Is Associated with Response to Chemotherapy and Prognosis in Colorectal Cancer

Cancers(2021)10.3390/cancers13061477

N/A

0DataRank · unranked

30 citations

Michelle R. Huyser, Lan Le, Yoshihisa Tokumaru, Li Yan, Ryusei Matsuyama +3 more

Quantitative global lipidomics analysis of patients with ovarian cancer versus benign adnexal mass

Scientific Reports(2021)10.1038/s41598-021-97433-x

N/A

0DataRank · unranked

29 citations

Charles W. Drescher, Nicole Urban, Christopher I. Li, Lisa Bettcher, Nitai C. Hait +5 more

Low expression of miR-29a is associated with aggressive biology and worse survival in gastric cancer

Scientific Reports(2021)10.1038/s41598-021-93681-z

N/A

0DataRank · unranked

22 citations

Masanori Oshi, Michelle R. Huyser, Li Yan, Masahiro Fukada, Nobuhisa Matsuhashi +5 more

Cytotoxic T-lymphocyte infiltration and chemokine predict long-term patient survival independently of tumor mutational burden in triple-negative breast cancer

Therapeutic Advances in Medical Oncology(2021)10.1177/17588359211006680

N/A

0DataRank · unranked

17 citations

Li Yan, Mateusz Opyrchal, Paweł Kaliński, Kazuaki Takabe, Eriko Katsuta

Novel genetic variants associated with mortality after unrelated donor allogeneic hematopoietic cell transplantation

EClinicalMedicine(2021)10.1016/j.eclinm.2021.101093

N/A

0DataRank · unranked

12 citations

Junke Wang, Leah Preus, Ezgi Karaesmen, Abbas Rizvi, Alyssa Clay‐Gilmour +17 more

Octogenarians’ Breast Cancer Is Associated with an Unfavorable Tumor Immune Microenvironment and Worse Disease-Free Survival

Cancers(2021)10.3390/cancers13122933

N/A

0DataRank · unranked

6 citations

Masanori Oshi, Swagoto Mukhopadhyay, Qianya Qi, Li Yan, Itaru Endo +3 more

G2M checkpoint signaling among six-cell proliferation-related pathway as a biomarker for prediction and prognosis in pancreatic cancer.

Journal of Clinical Oncology(2021)10.1200/jco.2021.39.15_suppl.e16264

N/A

0DataRank · unranked

1 citations

Lan Le, Yoshihisa Tokumaru, Li Yan, Ryusei Matsuyama, Itaru Endo +2 more

Abundance of reactive oxygen species (ROS) is associated with tumor aggressiveness, immune response, and worse survival in breast cancer

Breast Cancer Research and Treatment(2022)10.1007/s10549-022-06633-0

N/A

0DataRank · unranked

77 citations

Shipra Gandhi, Li Yan, Yoshihisa Tokumaru, Rongrong Wu, Akimitsu Yamada +4 more

Enhanced immune response outperform aggressive cancer biology and is associated with better survival in triple-negative breast cancer

npj Breast Cancer(2022)10.1038/s41523-022-00466-2

N/A

0DataRank · unranked

44 citations

Ankit Patel, Rongrong Wu, Lan Le, Yoshihisa Tokumaru, Akimitsu Yamada +6 more

NR2F1, a Tumor Dormancy Marker, Is Expressed Predominantly in Cancer-Associated Fibroblasts and Is Associated with Suppressed Breast Cancer Cell Proliferation

Cancers(2022)10.3390/cancers14122962

N/A

0DataRank · unranked

39 citations

Arya Mariam Roy, Yoshihisa Tokumaru, Shipra Gandhi, Mariko Asaoka, Masanori Oshi +4 more

Hepatic interferon regulatory factor 8 expression suppresses hepatocellular carcinoma progression and enhances the response to anti–programmed cell death protein‐1 therapy

Hepatology(2022)10.1002/hep.32316

N/A

0DataRank · unranked

35 citations

Li Yan, Guangjiang Shi, Shijia Du, Xiaobin Wang, Wanli Ye +10 more

Clinical Relevance of Estrogen Reactivity in the Breast Cancer Microenvironment

Frontiers in Oncology(2022)10.3389/fonc.2022.865024

N/A

0DataRank · unranked

20 citations

Yoshihisa Tokumaru, Masanori Oshi, Rongrong Wu, Ankit Patel, Wanqing Tian +5 more

UACA locus is associated with breast cancer chemoresistance and survival

npj Breast Cancer(2022)10.1038/s41523-022-00401-5

N/A

0DataRank · unranked

15 citations

Emily Schultz, Jirong Long, Janise M. Roh, Emily Valice, Cecile A. Laurent +14 more

High miR-99b expression is associated with cell proliferation and worse patient outcomes in breast cancer

Research Square(2022)10.21203/rs.3.rs-1963644/v1

N/A

0DataRank · unranked

13 citations

Yoshihisa Tokumaru, Matthew G.K. Benesch, Nobuhiko Sugito, Rongrong Wu, Li Yan +6 more

The clinical relevance of unfolded protein response signaling in breast cancer

Research Square(2022)10.21203/rs.3.rs-1480002/v1

N/A

0DataRank · unranked

9 citations

Arya Mariam Roy, Shipra Gandhi, Yoshihisa Tokumaru, Li Yan, Akimitsu Yamada +3 more

Development of a Machine Learning-Based Prognostic Model for Hormone Receptor-Positive Breast Cancer Using Nine-Gene Expression Signature

World Journal of Oncology(2023)10.14740/wjon1700

N/A

0DataRank · unranked

11 citations

Hirotaka Iwase, Rongrong Wu, Danya Ziazadeh, Li Yan, Kazuaki Takabe +1 more

Association of enhanced epithelial-mesenchymal transition signature with tumor microenvironment, angiogenesis, and survival in gastric cancer.

Journal of Clinical Oncology(2023)10.1200/jco.2023.41.16_suppl.e16002

N/A

0DataRank · unranked

2 citations

Li Yan, Chikara Kunisaki, Itaru Endo, Kazuaki Takabe, Masanori Oshi

Clinically and orally compatible formulation-manufactured DDX5 (p68)-targeting molecular glue FL118 products exhibit low toxicity but high efficacy against human cancer

Journal of Pharmaceutical Analysis(2024)10.1016/j.jpha.2024.101001

N/A

0DataRank · unranked

7 citations

Wenjie Wu, Li Yan, Leslie Curtin, Melanie M. Farrauto, Sandra Sexton +6 more

Enhanced cancer cell proliferation and aggressive phenotype counterbalance in breast cancer with high BRCA1 gene expression

Breast Cancer Research and Treatment(2024)10.1007/s10549-024-07421-8

N/A

0DataRank · unranked

7 citations

Masanori Oshi, Arya Mariam Roy, Takumi Sato, Maya Penelope Takabe, Li Yan +4 more

Photodynamic therapy reduces the burden of small ultraviolet-induced epidermal clones in human and mouse skin

British Journal of Dermatology(2024)10.1093/bjd/ljae314

N/A

0DataRank · unranked

3 citations

Megan E. Fitzgerald, Li Yan, Mitsuko Murakami, Sydney R. Grant, Qiang Hu +11 more

Higher Inflammatory Response in Hepatocellular Carcinoma is Associated with Immune Cell Infiltration and a Better Outcome

Research Square(2024)10.21203/rs.3.rs-3768964/v1

N/A

0DataRank · unranked

1 citations

Kohei Chida, Arya Mariam Roy, Gabriella Kim Mann, Nan An, Li Yan +3 more

BRSK2 plays a role in autophagy and cancer cell growth and survival under nutrient deprivation stress via the PIK3C3 pathway

Scientific Reports(2025)10.1038/s41598-025-24354-4

N/A

0DataRank · unranked

2 citations

Alison D. Axtman, Rongrong Wu, Lydia J. B. Redman, Kazuaki Takabe, Aimee Stablewski +7 more

Biologically targeted discovery-replication scan identifies G×G interaction in relation to risk of Barrett’s esophagus and esophageal adenocarcinoma

Human Genetics and Genomics Advances(2025)10.1016/j.xhgg.2025.100399

N/A

0DataRank · unranked

0 citations

Qianchuan He, Shiv P. Verma, Xu Zhang, Ann-Sophie Giel, Carlo Maj +20 more

M1 Macrophage and M1/M2 ratio defined by transcriptomic signatures resemble only part of their conventional clinical characteristics in breast cancer

Scientific Reports(2020)10.1038/s41598-020-73624-w

N/A

0DataRank · unranked

216 citations

Yoshihisa Tokumaru, Mariko Asaoka, Li Yan, Vikas Satyananda, Ryusei Matsuyama +7 more

Dual cutoffs of estrogen receptor positivity define prognostic and predictive subgroups in breast cancer

iScience(2025)10.1016/j.isci.2025.114486

N/A

0DataRank · unranked

0 citations

Hirotaka Iwase, Rongrong Wu, Takashi Ishikawa, Li Yan, Kazuaki Takabe +1 more

G2M Cell Cycle Pathway Score as a Prognostic Biomarker of Metastasis in Estrogen Receptor (ER)-Positive Breast Cancer

International Journal of Molecular Sciences(2020)10.3390/ijms21082921

N/A

0DataRank · unranked

165 citations

Hideo Takahashi, Yoshihisa Tokumaru, Li Yan, Omar M. Rashid, Ryusei Matsuyama +3 more

CD8 T Cell Score as a Prognostic Biomarker for Triple Negative Breast Cancer

International Journal of Molecular Sciences(2020)10.3390/ijms21186968

N/A

0DataRank · unranked

217 citations

Mariko Asaoka, Yoshihisa Tokumaru, Li Yan, Ryusei Matsuyama, Takashi Ishikawa +3 more

Li Yan

Indexed papers

Top data-sharing exemplar

Papers