Jashvant D. Unadkat

Also affiliated with American Pharmacists Association

MedicinePharmacology, Toxicology and Pharmaceutics

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

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Indexed papers

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 32 papers. Top paper: “Assessment of Orally Administered Δ9-Tetrahydrocannabinol When Coadministered With Cannabidiol on Δ9-Tetrahydrocannabinol Pharmacokinetics and Pharmacodynamics in Healthy Adults: A Randomized Clinical Trial”.

Assessment of Orally Administered Δ9-Tetrahydrocannabinol When Coadministered With Cannabidiol on Δ9-Tetrahydrocannabinol Pharmacokinetics and Pharmacodynamics in Healthy Adults: A Randomized Clinical Trial

JAMA Network Open(2023)10.1001/jamanetworkopen.2022.54752

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2.0DataRank · unranked

84 citations

Tory R. Spindle, Renuka Surujunarain, Elise M. Weerts, Sumit Bansal, Jashvant D. Unadkat +3 more

Gestational Age–Dependent Abundance of Human Placental Transporters as Determined by Quantitative Targeted Proteomics

Drug Metabolism and Disposition(2020)10.1124/dmd.120.000067

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74 citations

Bhagwat Prasad, Naveen K. Neradugomma, Joanne Wang, Qingcheng Mao, Jashvant D. Unadkat +1 more

Testicular Expression of Adora3i2 in Adora3 Knockout Mice Reveals a Role of Mouse A3Ri2 and Human A3Ri3 Adenosine Receptors in Sperm

UNC Libraries(2020)10.17615/eb5v-7v74

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Lindsey A. Burnett, Stephen L. Tilley, Edik M. Blais, Donner F. Babcock, Bertil Hille +1 more

Successful Prediction of Human Fetal Exposure to P-Glycoprotein Substrate Drugs Using the Proteomics-Informed Relative Expression Factor Approach and PBPK Modeling and Simulation

Drug Metabolism and Disposition(2021)10.1124/dmd.121.000538

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38 citations

Flavia Storelli, Jashvant D. Unadkat, Olena Anoshchenko

In Vitro–to–In Vivo Extrapolation of Transporter-Mediated Renal Clearance: Relative Expression Factor Versus Relative Activity Factor Approach

Drug Metabolism and Disposition(2021)10.1124/dmd.121.000367

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30 citations

Bhagwat Prasad, Deepak Bhatt, Sumathy Mathialagan, Manthena V. S. Varma, Jashvant D. Unadkat +1 more

Prediction of Pregnancy-Induced Changes in Secretory and Total Renal Clearance of Drugs Transported by Organic Anion Transporters

Drug Metabolism and Disposition(2021)10.1124/dmd.121.000557

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24 citations

Mayur K. Ladumor, Jashvant D. Unadkat, Jinfu Peng

Tetrahydrocannabinol and Its Major Metabolites Are Not (or Are Poor) Substrates or Inhibitors of Human P-Glycoprotein [ATP-Binding Cassette (ABC) B1] and Breast Cancer Resistance Protein (ABCG2)

Drug Metabolism and Disposition(2021)10.1124/dmd.121.000505

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21 citations

Jashvant D. Unadkat, Qingcheng Mao, Xin Chen

Modeling Pharmacokinetic Natural Product–Drug Interactions for Decision-Making: A NaPDI Center Recommended Approach

Pharmacological Reviews(2021)10.1124/pharmrev.120.000106

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18 citations

Dandan Tian, John Clarke, Allan E. Rettie, Jashvant D. Unadkat, Kenneth E. Thummel +3 more

Estimating fetal exposure to the P‐gp substrates, corticosteroids, by PBPK modeling to inform prevention of neonatal respiratory distress syndrome

CPT Pharmacometrics & Systems Pharmacology(2021)10.1002/psp4.12674

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17 citations

Mark A. Milad, Jashvant D. Unadkat, Olena Anoshchenko

Comprehensive Predictions of Cytochrome P450 (P450)-Mediated In Vivo Cannabinoid-Drug Interactions Based on Reversible and Time-Dependent P450 Inhibition in Human Liver Microsomes

Drug Metabolism and Disposition(2022)10.1124/dmd.121.000734

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65 citations

Mary F. Paine, Jashvant D. Unadkat, Sumit Bansal

The next frontier in ADME science: Predicting transporter-based drug disposition, tissue concentrations and drug-drug interactions in humans

Pharmacology & Therapeutics(2022)10.1016/j.pharmthera.2022.108271

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43 citations

Mengyue Yin, Aditya R. Kumar, Mayur K. Ladumor, Raymond Evers, Paresh P. Chothe +5 more

Predicting Human Fetal Drug Exposure Through Maternal‐Fetal PBPK Modeling and In Vitro or Ex Vivo Studies

The Journal of Clinical Pharmacology(2022)10.1002/jcph.2117

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27 citations

Aditya R. Kumar, Jashvant D. Unadkat, Ankit Balhara

Predicting Regional Respiratory Tissue and Systemic Concentrations of Orally Inhaled Drugs through a Novel PBPK Model

Drug Metabolism and Disposition(2022)10.1124/dmd.121.000789

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15 citations

Jashvant D. Unadkat, Mayur K. Ladumor

Estimation of Fetal-to-Maternal Unbound Steady-State Plasma Concentration Ratio of P-Glycoprotein and/or Breast Cancer Resistance Protein Substrate Drugs Using a Maternal-Fetal Physiologically Based Pharmacokinetic Model

Drug Metabolism and Disposition(2022)10.1124/dmd.121.000733

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11 citations

Mayur K. Ladumor, Jashvant D. Unadkat, Jinfu Peng

Maternal and Fetal Exposure to (-)-Δ9-tetrahydrocannabinol and Its Major Metabolites in Pregnant Mice Is Differentially Impacted by P-glycoprotein and Breast Cancer Resistance Protein

Drug Metabolism and Disposition(2022)10.1124/dmd.122.001110

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6 citations

Jashvant D. Unadkat, Qingcheng Mao, Xin Chen

P‐gp and Bcrp Exert Differential Impacts on Maternal and Fetal Exposure to Tetrahydrocannabinol and Its Major Metabolites in Pregnant Mice

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r5135

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Jashvant D. Unadkat, Qingcheng Mao, Xin Chen

Mechanisms of Transplacental Transfer of (‐)‐∆ 9‐Tetrahydrocannabinol (THC) in the Human Dual Cotyledon, Dual Perfusion, Placenta Model

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.0r546

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Nicholas Ieronimakis, Jashvant D. Unadkat, Aditya R. Kumar

Predicting Human Fetal Drug Exposure Through Maternal‐Fetal PBPK Modeling and In Vitro or Ex Vivo Studies

Zenodo (CERN European Organization for Nuclear Research)(2022)10.5281/zenodo.7938328

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Aditya R. Kumar, Jashvant D. Unadkat, Ankit Balhara

Evaluation of Cytochrome P450‐Mediated Cannabinoid‐Drug Interactions in Healthy Adult Participants

Clinical Pharmacology & Therapeutics(2023)10.1002/cpt.2973

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66 citations

C. Austin Zamarripa, Tory R. Spindle, Elise M. Weerts, Kenneth E. Thummel, Ryan G. Vandrey +3 more

The Impact of Inflammation on the In Vivo Activity of the Renal Transporters OAT1/3 in Pregnant Women Diagnosed with Acute Pyelonephritis

Pharmaceutics(2023)10.3390/pharmaceutics15102427

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6 citations

Patrícia Pereira dos Santos Melli, Geraldo Duarte, Jashvant D. Unadkat, Vera Lúcia Lanchote, Jhohann Richard de Lima Benzi

Regulation of Human Renal Drug Transporter mRNA Expression by Proinflammatory Cytokines

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.122.146890

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1 citations

Jashvant D. Unadkat, Qingcheng Mao, Yik Pui Tsang

Regulation of Hepatic Drug Transporters by Pro-inflammatory Cytokines

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.122.209420

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0 citations

Jashvant D. Unadkat, Qingcheng Mao, Tianran Hao

Dysregulation of the mRNA Expression of Human Renal Drug Transporters by Proinflammatory Cytokines in Primary Human Proximal Tubular Epithelial Cells

Pharmaceutics(2024)10.3390/pharmaceutics16020285

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16 citations

Tianran Hao, Qingcheng Mao, Edward J. Kelly, Jashvant D. Unadkat, Yik Pui Tsang

The effect of pregnancy-related hormones on hepatic transporters: studies with premenopausal human hepatocytes

Frontiers in Pharmacology(2024)10.3389/fphar.2024.1440010

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9 citations

Yik Pui Tsang, Jashvant D. Unadkat, Jhohann Richard de Lima Benzi

Effect of pregnancy-related hormones on mRNA expression of hepatic drug transporters and enzymes

Drug Metabolism and Pharmacokinetics(2024)10.1016/j.dmpk.2023.100808

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0 citations

Qingcheng Mao, Jashvant D. Unadkat, Jhohann Richard de Lima Benzi

Quantification and prediction of human fetal (-)-Δ9-tetrahydrocannabinol/(±)-11-OH-Δ9-tetrahydrocannabinol exposure during pregnancy to inform fetal cannabis toxicity

Nature Communications(2025)10.1038/s41467-025-55863-5

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8 citations

Lyndsey S. Benson, Erica Wymore, Jocelyn E. Phipers, Jennifer C. Dempsey, Lucinda A. Cort +2 more

Identification of selective substrates and inhibitors of the major human renal uptake transporters

Drug Metabolism and Disposition(2025)10.1016/j.dmd.2025.100046

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7 citations

Acilegna G. Rodriguez, Mark S. Warren, Jashvant D. Unadkat, Yik Pui Tsang

Regulation of expression and activity of hepatic transporters by pregnancy-related hormones in HepaRG cells

Drug Metabolism and Disposition(2025)10.1016/j.dmd.2025.100118

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4 citations

Jashvant D. Unadkat, Sejal Sharma

Does cannabidiol (CBD) or delta-9-tetrahydrocannabinol (THC) induce drug metabolizing enzymes in human hepatocytes?

Drug Metabolism and Pharmacokinetics(2025)10.1016/j.dmpk.2025.101126

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0 citations

Yik Pui Tsang, Jashvant D. Unadkat, Ankit Balhara

Rosuvastatin PBPK Modeling: Incorporating Liver Concentrations and Effects of Ethnicity, Genetic Polymorphisms, Lactone Formation, DDI and Pregnancy

CPT Pharmacometrics & Systems Pharmacology(2025)10.1002/psp4.70097

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0 citations

Robert H. Weber, Jashvant D. Unadkat, Ankit Balhara

Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450

Drug Metabolism and Disposition(2020)10.1124/dmd.120.000073

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88 citations

Neha Maharao, Mary F. Paine, Jashvant D. Unadkat, Sumit Bansal

Elucidating the role of ABC transporters in the placental efflux of (−)- Δ9-tetrahydrocannabinol (THC) using a cocktail of ABC transport inhibitors

Placenta(2025)10.1016/j.placenta.2025.12.012

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0 citations

Xin Chen, Aditya R. Kumar, Morgan Wasickanin, Joshua Monson, Jennifer R. Damicis +4 more