Karine G. Le Roch

Also affiliated with University of California System

MedicineImmunology and MicrobiologyBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 50 papers. Top paper: “The Arabidopsis PHD-finger protein EDM2 has multiple roles in balancing NLR immune receptor gene expression”.

The Arabidopsis PHD-finger protein EDM2 has multiple roles in balancing NLR immune receptor gene expression

PLOS Genetics(2020)10.1371/journal.pgen.1008993

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1.6DataRank · unranked

70 citations

Xueqing Maggie Lu, Josquin Daron, Songqin Pan, Jianqiang Wang, Wei Wang +8 more

Proteome-Wide Identification of RNA-dependent proteins and an emerging role for RNAs in Plasmodium falciparum protein complexes

Nature Communications(2024)10.1038/s41467-024-45519-1

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0.493DataRank · unranked

14 citations

Steven Abel, Charles A.S. Banks, Borislav H. Hristov, Jacques Prudhomme, Kianna Hales +4 more

Functional genomics of RAP proteins and their role in mitoribosome regulation in Plasmodium falciparum

Nature Communications(2022)10.1038/s41467-022-28981-7

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0.470DataRank · unranked

22 citations

Steven Abel, Alejandra Falla, Charisse Flerida A. Pasaje, Anil Bhatia, Manhoi Hur +8 more

PfAP2-MRP DNA-binding protein is a master regulator of parasite pathogenesis during malaria parasite blood stages

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.23.541898

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0.312DataRank · unranked

7 citations

Judith L. Green, Rohit Satyam, Todd Lenz, Rahul P. Salunke, Muhammad Shuaib +23 more

A newly characterized malaria antigen on erythrocyte and merozoite surfaces induces parasite inhibitory antibodies

The Journal of Experimental Medicine(2021)10.1084/jem.20200170

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0.241DataRank · unranked

4 citations

Sangshin Park, Shu‐Whei Tsai, Bonnie Rayta, Charisse Flerida A. Pasaje, Sara M. Nelson +14 more

Genome-wide functional analysis reveals key roles for kinesins in the mammalian and mosquito stages of the malaria parasite life cycle

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.26.445751

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0.165DataRank · unranked

2 citations

Ravish Rashpa, David Ferguson, Steven Abel, Zeinab Chahine, Declan Brady +7 more

Identification and phylogenetic analysis of RNA binding domain abundant in apicomplexans or RAP proteins

Microbial Genomics(2021)10.1099/mgen.0.000541

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0DataRank · unranked

12 citations

Lukasz Jaroszewski, Jason Stajich, Adam Godzik, Karine G. Le Roch, Thomas Hollin

Three-dimensional chromatin in infectious disease—A role for gene regulation and pathogenicity?

PLoS Pathogens(2021)10.1371/journal.ppat.1009207

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0DataRank · unranked

5 citations

Thomas Hollin, Todd Lenz, Karine G. Le Roch, Sage Z. Davis

Third-generation sequencing revises the molecular karyotype for Toxoplasma gondii and identifies emerging copy number variants in sexual recombinants

Genome Research(2021)10.1101/gr.262816.120

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0DataRank · unranked

32 citations

Aarthi Venkat, Rachel E. Bainbridge, Michael L. Reese, Karine G. Le Roch, Ferhat Ay +2 more

The transcriptional regulator HDP1 controls expansion of the inner membrane complex during early sexual differentiation of malaria parasites

Nature Microbiology(2022)10.1038/s41564-021-01045-0

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0DataRank · unranked

54 citations

Xinran Tong, Wei Xie, Steven Abel, Lindsey Orchard, Wassim Daher +5 more

Genome-wide functional analysis reveals key roles for kinesins in the mammalian and mosquito stages of the malaria parasite life cycle

PLoS Biology(2022)10.1371/journal.pbio.3001704

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0DataRank · unranked

23 citations

Ravish Rashpa, David Ferguson, Steven Abel, Zeinab Chahine, Declan Brady +7 more

Decrypting the complexity of the human malaria parasite biology through systems biology approaches

Frontiers in Systems Biology(2022)10.3389/fsysb.2022.940321

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0DataRank · unranked

8 citations

Karine G. Le Roch, Zeinab Chahine

Deciphering the non-coding code of pathogenicity and sexual differentiation in the human malaria parasite

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.12.511630

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0DataRank · unranked

3 citations

Xueqing Maggie Lu, Steven Abel, Zeinab Chahine, Borislav H. Hristov, Desiree Williams +15 more

Publisher Correction: The transcriptional regulator HDP1 controls expansion of the inner membrane complex during early sexual differentiation of malaria parasites

Nature Microbiology(2022)10.1038/s41564-022-01082-3

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0DataRank · unranked

1 citations

Xinran Tong, Wei Xie, Steven Abel, Lindsey Orchard, Wassim Daher +5 more

Babesia duncani multi-omics identifies virulence factors and drug targets

Nature Microbiology(2023)10.1038/s41564-023-01360-8

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0DataRank · unranked

44 citations

Stefano Lonardi, Qihua Liang, Pratap Vydyam, Eleonora Khabirova, Tiffany Fang +22 more

Plasmodium ARK2 and EB1 drive unconventional spindle dynamics, during chromosome segregation in sexual transmission stages

Nature Communications(2023)10.1038/s41467-023-41395-3

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0DataRank · unranked

41 citations

Edward Rea, Steven Abel, Kruno Vukušić, Róbert Márkus, Declan Brady +12 more

An ex vivo model of Toxoplasma recrudescence reveals developmental plasticity of the bradyzoite stage

mBio(2023)10.1128/mbio.01836-23

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0DataRank · unranked

23 citations

Amber L. Goerner, Arzu Ulu, David D. Hong, Kristina V. Bergersen, Michael A. Talavera +4 more

Autophagy in protists and their hosts: When, how and why?

Autophagy Reports(2023)10.1080/27694127.2022.2149211

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0DataRank · unranked

30 citations

Takahiko Akematsu, Sébastien Besteiro, Annina Bindschedler, Vern B. Carruthers, Zeinab Chahine +16 more

Novel insights into the role of long non-coding RNA in the human malaria parasite, Plasmodium falciparum

Nature Communications(2023)10.1038/s41467-023-40883-w

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0DataRank · unranked

22 citations

Xueqing Maggie Lu, Borislav H. Hristov, Steven Abel, Zeinab Chahine, Thomas Hollin +15 more

Epigenetic Regulation and Chromatin Remodeling in Malaria Parasites

Annual Review of Microbiology(2023)10.1146/annurev-micro-032521-041554

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0DataRank · unranked

21 citations

Zeinab Chahine, Karine G. Le Roch, Thomas Hollin

Small RNA sequencing of field Culex mosquitoes identifies patterns of viral infection and the mosquito immune response

Scientific Reports(2023)10.1038/s41598-023-37571-6

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0DataRank · unranked

15 citations

Zhenchen Hong, Desiree Williams, Sally W. Ireri, Michelle Q. Brown, Tianyun Su +5 more

An Enantiospecific Synthesis of Isoneoamphilectane Confirms Its Strained Tricyclic Structure

Journal of the American Chemical Society(2023)10.1021/jacs.2c13137

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0DataRank · unranked

9 citations

Zeinab Chahine, Karine G. Le Roch, Christopher D. Vanderwal, Natalie C. Dwulet

The role of long noncoding RNAs in malaria parasites

Trends in Parasitology(2023)10.1016/j.pt.2023.03.016

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0DataRank · unranked

15 citations

Zeinab Chahine, Karine G. Le Roch, Trevor A. Thompson

A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.31.526483

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0DataRank · unranked

23 citations

Malina A. Bakowski, Amélie Vantaux, Erika L. Flannery, Chiara Andolina, Manoj Kumar Gupta +43 more

PfMORC protein regulates chromatin accessibility and transcriptional repression in the human malaria parasite, Plasmodium falciparum

eLife(2023)10.7554/elife.92499

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0DataRank · unranked

12 citations

Mohit Gupta, Todd Lenz, Thomas Hollin, Steven Abel, Charles A.S. Banks +6 more

Plasmodium ARK2-EB1 axis drives the unconventional spindle dynamics, scaffold formation and chromosome segregation of sexual transmission stages

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.29.526106

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0DataRank · unranked

3 citations

Edward Rea, Steven Abel, Kruno Vukušić, Róbert Márkus, Declan Brady +12 more

Plasmodium ARK2-EB1 axis drives the unconventional spindle dynamics, scaffold formation and chromosome segregation of sexual transmission stages

Research Square(2023)10.21203/rs.3.rs-2539372/v1

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0DataRank · unranked

3 citations

Edward Rea, Steven Abel, Kruno Vukušić, Róbert Márkus, Declan Brady +12 more

Toxoplasma gondii F-Box Protein L2 Silences Feline-Restricted Genes Necessary for Sexual Commitment

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.18.572150

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0DataRank · unranked

1 citations

Sarah Hosking, Elisabet Gas‐Pascual, Loic Ciampossine, Steven Abel, Mohamed‐Ali Hakimi +5 more

Reviewer #2 (Public Review): PfMORC protein regulates chromatin accessibility and transcriptional repression in the human malaria parasite, P. falciparum

(2023)10.7554/elife.92499.1.sa0

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0DataRank · unranked

0 citations

Mohit Gupta, Todd Lenz, Thomas Hollin, Steven Abel, CAS Banks +5 more

Insights into the evolution, virulence and speciation of Babesia MO1 and Babesia divergens through multiomics analyses

Emerging Microbes & Infections(2024)10.1080/22221751.2024.2386136

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0DataRank · unranked

17 citations

Pratap Vydyam, Tiffany Fang, Karel Estrada, Luís Miguel González, Ricardo Grande +18 more

A Divergent Synthesis of Numerous Pyrroloiminoquinone Alkaloids Identifies Promising Antiprotozoal Agents

Journal of the American Chemical Society(2024)10.1021/jacs.4c11897

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0DataRank · unranked

12 citations

Nicholas L. Magann, Daniele Perrotta, Fabian M. Hörmann, Sebastian Fernandez, Pratap Vydyam +7 more

A kalihinol analog disrupts apicoplast function and vesicular trafficking in P. falciparum malaria

Science(2024)10.1126/science.adm7966

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0DataRank · unranked

13 citations

Steffen Abel, Thomas Hollin, Griffin L. Barnes, Jing-Gung Chung, Mary Elisabeth Daub +24 more

A drug repurposing approach reveals targetable epigenetic pathways in Plasmodium vivax hypnozoites

eLife(2024)10.7554/elife.98221

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0DataRank · unranked

3 citations

Malina A. Bakowski, Amélie Vantaux, Erika L. Flannery, Chiara Andolina, Mohit Gupta +43 more

Multiomics analysis reveals B. MO1 as a distinct Babesia species and provides insights into its evolution and virulence

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.17.575932

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0DataRank · unranked

1 citations

Pratap Vydyam, Tiffany Fang, Karel Estrada, Luís Miguel González, Ricardo Grande +18 more

A Divergent Synthesis of Numerous Pyrroloiminoquinone Alkaloids Identifies Promising Antiprotozoal Agents

ChemRxiv(2024)10.26434/chemrxiv-2024-9tvnq

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0DataRank · unranked

1 citations

Nicholas L. Magann, Daniele Perrotta, Fabian M. Hörmann, Sebastian Fernandez, Pratap Vydyam +7 more

Chromatin structure and var2csa – a tango in regulation of var gene expression in the human malaria parasite, Plasmodium falciparum ?

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.13.580059

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0DataRank · unranked

0 citations

Xu Zhang, Abhijit Chakraborty, Abbas Roayaei Ardakany, Jacques Prudhomme, Ferhat Ay +3 more

Epigenetics and chromatin structure regulate var2csa expression and the placental-binding phenotype in Plasmodium falciparum

eLife(2024)10.7554/elife.93632

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0DataRank · unranked

0 citations

Madle Sirel, Hannes Hoppe, Sulman Shafeeq, Karine G. Le Roch, Ulf Ribacke +1 more

Author response: A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites

(2024)10.7554/elife.98221.1.sa4

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0DataRank · unranked

0 citations

Malina A. Bakowski, Amélie Vantaux, Erika L. Flannery, Chiara Andolina, Manoj Kumar Gupta +43 more

The Toxoplasma rhoptry protein ROP55 is a major virulence factor that prevents lytic host cell death

Nature Communications(2025)10.1038/s41467-025-56128-x

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0DataRank · unranked

6 citations

Ji‐Hun Shin, Todd Lenz, Stephanie Y. Matsuno, Katherine Olivia Yanes, Arnault Graindorge +9 more

RAP proteins regulate apicoplast noncoding RNA processing in Plasmodium falciparum

Cell Reports(2025)10.1016/j.celrep.2025.115928

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0DataRank · unranked

5 citations

Zeinab Chahine, Steven Abel, Charles A.S. Banks, Charisse Flerida A. Pasaje, Todd Lenz +7 more

A drug repurposing approach reveals targetable epigenetic pathways in Plasmodium vivax hypnozoites

eLife(2025)10.7554/elife.98221.2

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0DataRank · unranked

1 citations

Malina A. Bakowski, Amélie Vantaux, Erika L. Flannery, Chiara Andolina, Mohit Gupta +43 more

Epigenetic reprogramming restores metronidazole sensitivity in drug-resistant Trichomonas vaginalis parasites

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.07.631743

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0DataRank · unranked

0 citations

Daniela Muñoz, Ayelén Lizarraga, Verónica M. Cóceres, Lucrecia S. Iriarte, Natalia de Miguel +4 more

A divergent Plasmodium NEK4 acts as a key regulator driving the early events of meiosis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.21.689802

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0DataRank · unranked

0 citations

Molly Hair, Mohammad Zeeshan, David Ferguson, Declan Brady, Carla Pasquarello +11 more

Contributors

Genomic and Personalized Medicine(2013)10.1016/b978-0-12-382227-7.00124-5

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0DataRank · unranked

0 citations

Minhaz Uddin Ahmed, Sun Hee Ahn, R. Rand Allingham, Jude Alsarraj, Matthew L. Anderson +228 more

A divergent Plasmodium NEK4 acts as a key regulator driving the early events of meiosis

Research Square(2025)10.21203/rs.3.rs-8180258/v1

N/A

0DataRank · unranked

0 citations

Ryuji Yanase, Molly Hair, Mohammad Zeeshan, David Ferguson, Declan Brady +11 more

From Genes to Transcripts, a Tightly Regulated Journey in Plasmodium

Frontiers in Cellular and Infection Microbiology(2020)10.3389/fcimb.2020.618454

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0DataRank · unranked

69 citations

Karine G. Le Roch, Thomas Hollin

Real-time dynamics of Plasmodium NDC80 reveals unusual modes of chromosome segregation during parasite proliferation

Journal of Cell Science(2020)10.1242/jcs.245753

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0DataRank · unranked

68 citations

Rajan Pandey, David Ferguson, Eelco C. Tromer, Róbert Márkus, Steven Abel +10 more

Plasmodium Condensin Core Subunits SMC2/SMC4 Mediate Atypical Mitosis and Are Essential for Parasite Proliferation and Transmission

Cell Reports(2020)10.1016/j.celrep.2020.01.033

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0DataRank · unranked

40 citations

Steven Abel, Matthew Boucher, Richard J. Wall, Mohammad Zeeshan, Edward Rea +14 more

Dynamic Chromatin Structure and Epigenetics Control the Fate of Malaria Parasites

Trends in Genetics(2020)10.1016/j.tig.2020.09.003

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0DataRank · unranked

32 citations

Mohit Gupta, Todd Lenz, Karine G. Le Roch, Thomas Hollin

Measuring significant changes in chromatin conformation with ACCOST

Nucleic Acids Research(2020)10.1093/nar/gkaa069

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0DataRank · unranked

29 citations

Borislav H. Hristov, Karine G. Le Roch, Jean‐Philippe Vert, William Stafford Noble, Kate B. Cook