Hiroyuki Inuzuka

Also affiliated with Harvard University, Hadassah Medical Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 36 papers. Top paper: “Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle”.

Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle

Cell Research(2020)10.1038/s41422-020-0372-z

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0DataRank · unranked

117 citations

Yunhua Peng, Le Shi, Lixin Wan, Hiroyuki Inuzuka, Jiangang Long +14 more

G protein–coupled receptor Gpr115 (Adgrf4) is required for enamel mineralization mediated by ameloblasts

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.014281

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0DataRank · unranked

19 citations

Keigo Yoshizaki, Kan Saito, T Ikeuchi, Tsutomu Iwamoto, Craig Rhodes +12 more

pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner

UNC Libraries(2020)10.17615/792d-1w31

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4 citations

Jinfang Zhang, Hiroyuki Inuzuka, Xingnan Zheng, Wenjian Gan, Abhishek A. Chakraborty +13 more

Interplay between protein acetylation and ubiquitination controls MCL1 protein stability

Cell Reports(2021)10.1016/j.celrep.2021.109988

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0DataRank · unranked

61 citations

Min Gi, Shugo Suzuki, Brian J. North, Asami Watahiki, Satoshi Fukumoto +5 more

Necroptosis pathways in tumorigenesis

Seminars in Cancer Biology(2022)10.1016/j.semcancer.2022.07.007

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0DataRank · unranked

92 citations

Yingnan Wang, Hiroyuki Inuzuka, Wenyi Wei, Tao Zhang

PROTAC technology for the treatment of Alzheimer’s disease: advances and perspectives

Acta Materia Medica(2022)10.15212/amm-2021-0001

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0DataRank · unranked

47 citations

Jing Liu, Wenyi Wei, Abdol-Hossein Rezaeian, Hiroyuki Inuzuka

Ring domains are essential for GATOR2-dependent mTORC1 activation

Molecular Cell(2022)10.1016/j.molcel.2022.11.021

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0DataRank · unranked

33 citations

Xiaoming Dai, Shaohui He, Hongfei Zhou, Lan Fang, Jianping Guo +11 more

Regulation of neuronal autophagy and cell survival by MCL1 in Alzheimer’s disease

Acta Materia Medica(2022)10.15212/amm-2021-0002

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0DataRank · unranked

27 citations

Wenyi Wei, Hiroyuki Inuzuka, Abdol-Hossein Rezaeian

Acetylation-dependent regulation of BRAF oncogenic function

Cell Reports(2022)10.1016/j.celrep.2021.110250

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0DataRank · unranked

24 citations

Xiaoling Zhang, Qing Yin, Jia Hu, Jianping Guo, Yang Gao +5 more

Targeting micro-environmental pathways by PROTACs as a therapeutic strategy

Seminars in Cancer Biology(2022)10.1016/j.semcancer.2022.07.001

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0DataRank · unranked

18 citations

Yunhua Peng, Hiroyuki Inuzuka, Wenyi Wei, Jing Liu

Insights into the aberrant CDK4/6 signaling pathway as a therapeutic target in tumorigenesis

Advances in protein chemistry and structural biology(2022)10.1016/bs.apcsb.2022.11.009

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12 citations

Hiroyuki Inuzuka, Wenyi Wei, Abdol-Hossein Rezaeian

Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1

Science(2023)10.1126/science.abn1725

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0DataRank · unranked

123 citations

Daichao Xu, Elijah Trefts, Mingming Lv, Hiroyuki Inuzuka, Guobin Song +35 more

Targeted protein posttranslational modifications by chemically induced proximity for cancer therapy

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104572

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0DataRank · unranked

61 citations

Jing Liu, Hiroyuki Inuzuka, Wenyi Wei, Yunhua Peng

Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation

Nature Cell Biology(2023)10.1038/s41556-023-01170-4

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0DataRank · unranked

61 citations

Daichao Xu, Jianping Liu, Min Wang, Li‐Juan Duan, Min Liu +34 more

AMPK-dependent phosphorylation of the GATOR2 component WDR24 suppresses glucose-mediated mTORC1 activation

Nature Metabolism(2023)10.1038/s42255-022-00732-4

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0DataRank · unranked

41 citations

Cong Jiang, Qiwei Jiang, Lan Fang, Haihong Yu, Jinhe Guo +9 more

PRMT1 orchestrates with SAMTOR to govern mTORC1 methionine sensing via Arg-methylation of NPRL2

Cell Metabolism(2023)10.1016/j.cmet.2023.11.001

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0DataRank · unranked

39 citations

Jing Liu, Shaohui He, Wei Xu, Runzhi Huang, Weijuan Pan +10 more

USP2 inhibition prevents infection with ACE2-dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice

Science Translational Medicine(2023)10.1126/scitranslmed.adh7668

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19 citations

Lei Bai, Jiazhen Dong, Xiaoping Hu, Jingchao Wang, Joao A. Paulo +22 more

Methylated Nucleotide-Based Proteolysis-Targeting Chimera Enables Targeted Degradation of Methyl-CpG-Binding Protein 2

Journal of the American Chemical Society(2023)10.1021/jacs.3c06023

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13 citations

Jing Liu, Xing Qiu, Dingpeng Zhang, Hiroyuki Inuzuka, Li Chen +7 more

Structurally Specific Z-DNA Proteolysis Targeting Chimera Enables Targeted Degradation of Adenosine Deaminase Acting on RNA 1

Journal of the American Chemical Society(2024)10.1021/jacs.3c13646

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30 citations

Dingpeng Zhang, Xing Qiu, Hiroyuki Inuzuka, Yan Xiong, Jing Liu +8 more

USP7-Based Deubiquitinase-Targeting Chimeras Stabilize AMPK

Journal of the American Chemical Society(2024)10.1021/jacs.4c02373

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0DataRank · unranked

29 citations

Xiaoping Hu, Kaixiu Luo, Yan Xiong, Li Chen, Zhen Wang +11 more

Molecular insights and clinical implications for the tumor suppressor role of SCFFBXW7 E3 ubiquitin ligase

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer(2024)10.1016/j.bbcan.2024.189140

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0DataRank · unranked

22 citations

Abdol-Hossein Rezaeian, Jingchao Wang, Daoyuan Huang, Hong Chen, Hiroyuki Inuzuka +2 more

O-GlcNAcylation in tumorigenesis and its implications for cancer therapy

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107709

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0DataRank · unranked

22 citations

Yihang Qi, Hiroyuki Inuzuka, Jing Liu, Wenyi Wei, Dize Zhang

The First‐In‐Class Deubiquitinase‐Targeting Chimera Stabilizes and Activates cGAS

Angewandte Chemie International Edition(2024)10.1002/anie.202415168

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0DataRank · unranked

20 citations

Li Chen, Chao Qian, Jing Liu, Qiong Wu, Xiangyang Song +12 more

Identification of a distal enhancer regulating hedgehog interacting protein gene in human lung epithelial cells

EBioMedicine(2024)10.1016/j.ebiom.2024.105026

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0DataRank · unranked

10 citations

Li Zhang, Yuzhen Yu, Lu Gong, Shiyue Tao, Rhiannon B. Werder +17 more

Targeting the PRMT1-cGAS-STING signaling pathway to enhance the anti-tumor therapeutic efficacy

Journal of Cancer Biology(2024)10.46439/cancerbiology.5.064

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0DataRank · unranked

8 citations

Abdol-Hossein Rezaeian, Jingchao Wang, Yihang Qi, Hong Chen, Hiroyuki Inuzuka +2 more

Targeted Degradation of Receptor-Interacting Protein Kinase 1 to Modulate the Necroptosis Pathway

ACS Pharmacology & Translational Science(2024)10.1021/acsptsci.4c00421

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0DataRank · unranked

6 citations

Chao Qian, Yihang Qi, Yan Xiong, Chaoyu Wang, Zhen Wang +5 more

USP28-Based Deubiquitinase-Targeting Chimeras for Cancer Treatment

Journal of the American Chemical Society(2025)10.1021/jacs.5c01889

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0DataRank · unranked

19 citations

C. D. Qian, Yan Xiong, Dingpeng Zhang, Hiroyuki Inuzuka, Yue Zhong +5 more

Molecular Subtypes and Targeted Therapeutic Strategies in Small Cell Lung Cancer: Advances, Challenges, and Future Perspectives

Molecules(2025)10.3390/molecules30081731

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0DataRank · unranked

18 citations

Jingchao Wang, Li Chen, Weiwei Jiang, Hiroyuki Inuzuka, David K. Simon +2 more

Harnessing the Deubiquitinase USP1 for Targeted Protein Stabilization

Journal of the American Chemical Society(2025)10.1021/jacs.5c01662

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0DataRank · unranked

13 citations

Zhen Wang, Yan Xiong, Dingpeng Zhang, Yue Zhong, Hiroyuki Inuzuka +6 more

Dual membrane receptor degradation via folate receptor targeting chimera

Nature Communications(2025)10.1038/s41467-025-63882-5

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0DataRank · unranked

10 citations

Zhixin Li, Jenny Högström, Hiroyuki Inuzuka, Rui Jing, Peiqiang Yan +11 more

Deubiquitinase-Targeting Chimeras Mediated Stabilization of Tumor Suppressive E3 Ligase Proteins as a Strategy for Cancer Therapy

Journal of the American Chemical Society(2025)10.1021/jacs.5c06306

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0DataRank · unranked

7 citations

Zhijie Deng, Yan Xiong, Jing Liu, Daoyuan Huang, Jingchao Wang +7 more

PROTAC technology for prostate cancer treatment

Acta Materia Medica(2025)10.15212/amm-2024-0075

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0DataRank · unranked

7 citations

Dingpeng Zhang, Hiroyuki Inuzuka, Wenyi Wei, Zhen Wang

Targeting the PARylation-Dependent Ubiquitination Signaling Pathway for Cancer Therapies

Biomolecules(2025)10.3390/biom15020237

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0DataRank · unranked

7 citations

Jingchao Wang, Li Chen, Weiwei Jiang, Hiroyuki Inuzuka, David K. Simon +2 more

Targeting the cell-cycle machinery for cancer therapy

Trends in Cell Biology(2025)10.1016/j.tcb.2025.08.008

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0DataRank · unranked

4 citations

Jiejing Liu, Hiroyuki Inuzuka, Wenyi Wei, Jing Liu, Yunhua Peng

HHIP protein interactions in lung cells provide insight into COPD pathogenesis

Human Molecular Genetics(2025)10.1093/hmg/ddaf016

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0DataRank · unranked

3 citations

Hiroyuki Inuzuka, Peter J. Castaldi, Jeong H. Yun, Zhonghui Xu, Wardatul Jannat Anamika +7 more

Targeting aging-related signaling pathways for cancer therapy

Seminars in Cancer Biology(2025)10.1016/j.semcancer.2025.12.007

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0DataRank · unranked

0 citations

Wenyi Wei, Hiroyuki Inuzuka