Colin G. Nichols

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 39 papers. Top paper: “Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes”.

Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes

eLife(2023)10.7554/elife.71154

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0.656DataRank · unranked

23 citations

Grigory Maksaev, Zainab Harissa, Alireza Savadipour, Ruhang Tang, Nancy Steward +5 more

Macrophage secretion of miR-106b-5p causes renin-dependent hypertension

Nature Communications(2020)10.1038/s41467-020-18538-x

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52 citations

Scot J. Matkovich, Amy E. Riek, Sharell M. Bindom, J.-S. Shao, Richard D. Head +15 more

Preferential Gq signaling in diabetes: an electrical switch in incretin action and in diabetes progression?

Journal of Clinical Investigation(2020)10.1172/jci143199

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10 citations

N York, Marı́a S. Remedi, Colin G. Nichols

Pathophysiological Consequences of KATP Channel Overactivity and Pharmacological Response to Glibenclamide in Skeletal Muscle of a Murine Model of Cantù Syndrome

Frontiers in Pharmacology(2020)10.3389/fphar.2020.604885

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30 citations

Fatima Maqoud, Nicola Zizzo, Antonietta Mele, Giulia Maria Camerino, Francesco Alfredo Zito +6 more

Kir6.1- and SUR2-dependent KATP overactivity disrupts intestinal motility in murine models of Cantú syndrome

JCI Insight(2020)10.1172/jci.insight.141443

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27 citations

Helen L. Parker, Zili Xie, David Tyus, Maham Akbar Waheed, Zihan Yan +6 more

The Mechanism of High-Output Cardiac Hypertrophy Arising From Potassium Channel Gain-of-Function in Cantú Syndrome

Function(2020)10.1093/function/zqaa004

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24 citations

Yan Huang, Scot J. Matkovich, Attila Kovács, Carla J. Weinheimer, R. García Pérez +6 more

Consequences of SUR2[A478V] Mutation in Skeletal Muscle of Murine Model of Cantu Syndrome

Cells(2021)10.3390/cells10071791

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17 citations

Fatima Maqoud, Nicola Zizzo, Giuseppe Passantino, Antonietta Mele, Giulia Maria Camerino +5 more

Complex consequences of Cantu syndrome SUR2 variant R1154Q in genetically modified mice

JCI Insight(2021)10.1172/jci.insight.145934

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16 citations

Alex Hanson, Tobias Scherf de Almeida, Christopher H. Emfinger, Conor McClenaghan, Theresa M. Harter +11 more

Pore-forming transmembrane domains control ion selectivity and selectivity filter conformation in the KirBac1.1 potassium channel

The Journal of General Physiology(2021)10.1085/jgp.202012683

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11 citations

Colin G. Nichols, Marcos Matamoros

Genome-edited zebrafish model of ABCC8 loss-of-function disease

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.10.461291

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0 citations

Robert C. Tryon, Soma S. Singareddy, N York, Marı́a S. Remedi, Colin G. Nichols +1 more

The Polyamine Spermine Potentiates the Propagation of Negatively Charged Molecules through the Astrocytic Syncytium

Biomolecules(2022)10.3390/biom12121812

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6 citations

Christian J. Malpica-Nieves, Yomarie Rivera, Miguel P. Méndez-González, Colin G. Nichols, Rüdiger W. Veh +3 more

Lymphedema as first clinical presentation of Cantu Syndrome: reversed phenotyping after identification of gain-of-function variant in ABCC9

European Journal of Human Genetics(2022)10.1038/s41431-022-01210-x

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6 citations

Conor McClenaghan, Imke Christiaans, Mariëlle Alders, Kirsten van Duinen, Mieke M. van Haelst +3 more

Genome-edited zebrafish model of ABCC8 loss-of-function disease

Islets(2022)10.1080/19382014.2022.2149206

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5 citations

Robert C. Tryon, Soma S. Singareddy, N York, Marı́a S. Remedi, Colin G. Nichols +1 more

Seeing spermine blocking of K+ ion movement through inward rectifier Kir2.2 channels

The Journal of General Physiology(2022)10.1085/jgp.202213144

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5 citations

Colin G. Nichols, Sun-Joo Lee

The T1‐tetramerisation domain of Kv1.2 rescues expression and preserves function of a truncated NaChBac sodium channel

FEBS Letters(2022)10.1002/1873-3468.14279

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0 citations

Andrew J. Miles, Andrew M. Powl, Colin G. Nichols, B.A. Wallace, Andrias O. O’Reilly +1 more

Oxidation driven reversal of PIP2-dependent gating in GIRK2 channels

Research Square(2022)10.21203/rs.3.rs-1792750/v1

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0 citations

Colin G. Nichols, Sun‐Joo Lee

KATP channels are necessary for glucose-dependent increases in amyloid-β and Alzheimer’s disease–related pathology

JCI Insight(2023)10.1172/jci.insight.162454

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27 citations

William R. Moritz, Morgan C. Pait, Molly Stanley, Sarah Kaye, Caitlin M. Carroll +17 more

Lymphatic contractile dysfunction in mouse models of Cantú Syndrome with KATP channel gain-of-function

Function(2023)10.1093/function/zqad017

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26 citations

Jorge A. Castorena‐Gonzalez, Hae Jin Kim, Min Li, Marı́a S. Remedi, Colin G. Nichols +1 more

Glucokinase Inhibition: A Novel Treatment for Diabetes?

Diabetes(2023)10.2337/db22-0731

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12 citations

Colin G. Nichols, Marı́a S. Remedi

Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATP Channel Mutations in Intact Cells

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.123.001659

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13 citations

Conor McClenaghan, Kenneth A. Matreyek, Dorothy K. Grange, Colin G. Nichols, Jian Gao

Skeletal muscle delimited myopathy and verapamil toxicity in SUR2 mutant mouse models of AIMS

EMBO Molecular Medicine(2023)10.15252/emmm.202216883

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8 citations

Maya Mukadam, Jacob Roeglin, Robert C. Tryon, Manfred Grabner, Anamika Dayal +3 more

Subunit gating resulting from individual protonation events in Kir2 channels

Nature Communications(2023)10.1038/s41467-023-40058-7

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11 citations

Michael Bründl-Jirout, Anna Stary‐Weinzinger, Eva‐Maria Zangerl‐Plessl, Sun‐Joo Lee, Colin G. Nichols +1 more

Conformational plasticity of NaK2K and TREK2 potassium channel selectivity filters

Nature Communications(2023)10.1038/s41467-022-35756-7

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10 citations

Xue Wen Ng, Joshua Brettmann, David W. Piston, Colin G. Nichols, Marcos Matamoros

Blockade of TRPV channels by intracellular spermine

The Journal of General Physiology(2023)10.1085/jgp.202213273

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10 citations

Peng Yuan, Colin G. Nichols, Grigory Maksaev

Oxidation Driven Reversal of PIP2-dependent Gating in GIRK2 Channels

Function(2023)10.1093/function/zqad016

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5 citations

Shoji Maeda, Jian Gao, Colin G. Nichols, Sun‐Joo Lee

Electrophysiology of human iPSC-derived vascular smooth muscle cells and cell autonomous consequences of Cantu Syndrome mutations

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.29.547088

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1 citations

Conor McClenaghan, Kuo‐Chan Weng, Sarah Colijn, Amber N. Stratman, Carmen M. Halabi +4 more

Subunit gating resulting from individual protonation events in Kir2 channels

Research Square(2023)10.21203/rs.3.rs-2640647/v1

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0DataRank · unranked

0 citations

Michael Bründl-Jirout, Anna Stary‐Weinzinger, Eva‐Maria Zangerl‐Plessl, Sun‐Joo Lee, Colin G. Nichols +1 more

Novel loss-of-function variants expand ABCC9-related intellectual disability and myopathy syndrome

Brain(2024)10.1093/brain/awae010

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14 citations

Marcello Scala, Vini Nagaraj, Katarzyna Ochenkowska, Fenne L. Komdeur, Robin A Liang +24 more

Loss of β-Cell KATP Reduces Ca2+ Sensitivity of Insulin Secretion and Trpm5 Expression

Diabetes(2024)10.2337/db24-0650

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12 citations

Zihan Yan, Anna B. Osipovich, Abbie Tate, Sumit Patel, David W. Piston +4 more

A novel ABCC9 variant in a Greek family with Cantu syndrome affecting multiple generations highlights the functional role of the SUR2B NBD1

American Journal of Medical Genetics Part A(2024)10.1002/ajmg.a.63815

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2 citations

Athina Ververi, Ellen J. Thompson, Rob Tryon, Alexandros Sotiriadis, Fotios Rouvalis +4 more

Modulation of TMEM16B channel activity by the calcium-activated chloride channel regulator 4 (CLCA4) in human cells

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107432

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4 citations

Zeynep Yurtsever, Kayla N. Berry, Conor McClenaghan, Alyssa J Foy, Alex Hanson +7 more

Electrophysiology of Human iPSC-derived Vascular Smooth Muscle Cells and Cell-autonomous Consequences of Cantú Syndrome Mutations

Function(2024)10.1093/function/zqae027

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0 citations

Conor McClenaghan, Kuo‐Chan Weng, Sarah Colijn, Amber N. Stratman, Carmen M. Halabi +4 more

From Selective Permeation to Physiology in Potassium Channels

Function(2025)10.1093/function/zqaf050

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4 citations

Johanna Schillings, Reinier de Vries, Marcos Matamoros, Bert L. de Groot, Colin G. Nichols +1 more

Muscle fatigue arising intrinsically from SUR2- but not Kir6.1-dependent gain-of-function in Cantu syndrome mice

The Journal of General Physiology(2025)10.1085/jgp.202513781

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3 citations

Maya Mukadam, Y. Stefanie Chen, Courtney Frazier, N York, Robert C. Tryon +3 more

Dynein light chains 1 and 2 are auxiliary proteins of pH-sensitive Kir4.1 channels

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108393

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1 citations

Jian Gao, Ellen J. Thompson, Jonathan Mount, Colin G. Nichols, Sun-Joo Lee

Bayliss–Starling Prize Lecture: KATP channel pathophysiology – a whole‐body odyssey

The Journal of Physiology(2025)10.1113/jp287415

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1 citations

Colin G. Nichols

PIP2-driven cytoplasmic domain motions are coupled to Kir2 channel gating

The Journal of General Physiology(2025)10.1085/jgp.202513864

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1 citations

Anna Stary‐Weinzinger, Colin G. Nichols, Sun‐Joo Lee, Eva‐Maria Zangerl‐Plessl

Coronavirus Proteins as Ion Channels: Current and Potential Research

Frontiers in Immunology(2020)10.3389/fimmu.2020.573339

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76 citations

Alex Hanson, Sun‐Joo Lee, Colin G. Nichols, Conor McClenaghan

Cantu syndrome–associated SUR2[H60Y] mutation confers selective gain of function on Kir6.1 ATP-sensitive potassium channels

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.111105

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0 citations

Ellen T. Thompson, Colin G. Nichols, Jian Gao