Jae‐Hyuck Shim

Also affiliated with University of Massachusetts Chan Medical School, Gene Therapy Laboratory, Institute for Medical Research, UMass Memorial Medical Center

Biochemistry, Genetics and Molecular BiologyImmunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 30 papers. Top paper: “Osteoblast-Osteoclast Communication and Bone Homeostasis”.

Osteoblast-Osteoclast Communication and Bone Homeostasis

Cells(2020)10.3390/cells9092073

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1.0DataRank · unranked

1078 citations

Chujiao Lin, Zheni Stavre, Matthew B. Greenblatt, Jae‐Hyuck Shim, Jung‐Min Kim

The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

eLife(2024)10.7554/elife.101984

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0.107DataRank · unranked

1 citations

Yuan Wang, Luyang Zhang, Chunjie Wang, Deping Chen, Haibo Liu +5 more

Bone-Targeting AAV-Mediated Gene Silencing in Osteoclasts for Osteoporosis Therapy

Molecular Therapy — Methods & Clinical Development(2020)10.1016/j.omtm.2020.04.010

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0DataRank · unranked

49 citations

Jun Xie, Sachin Chaugule, Dan Wang, Jung‐Min Kim, JiHea Kim +6 more

MEKK2 mediates aberrant ERK activation in neurofibromatosis type I

Nature Communications(2020)10.1038/s41467-020-19555-6

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0DataRank · unranked

16 citations

Dong Yeon Shin, Alisha R. Yallowitz, Mark Eiseman, Michelle Cung, Ren Xu +8 more

TAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization

Biochemical and Biophysical Research Communications(2020)10.1016/j.bbrc.2020.07.060

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0DataRank · unranked

31 citations

Hwanhee Oh, Michelle Cung, Sofia Jenia Marquez, Jun Sun, Hamida Hammad +7 more

The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.03.233874

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0DataRank · unranked

0 citations

Yuan Wang, Luyang Zhang, Chunjie Wang, Deping Chen, Haibo Liu +5 more

Trabecular bone organoid model for studying the regulation of localized bone remodeling

Science Advances(2021)10.1126/sciadv.abd6495

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0DataRank · unranked

146 citations

Eugene Cheong, Jun‐Goo Kwak, Ryan Carpenter, Jae‐Hyuck Shim, Jungwoo Lee +1 more

SLITRK5 is a negative regulator of hedgehog signaling in osteoblasts

Nature Communications(2021)10.1038/s41467-021-24819-w

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0DataRank · unranked

31 citations

Dong Yeon Shin, Mark Eiseman, Alisha R. Yallowitz, Na Li, Sarfaraz Lalani +13 more

Cellular and Tissue Selectivity of AAV Serotypes for Gene Delivery to Chondrocytes and Cartilage

International Journal of Medical Sciences(2021)10.7150/ijms.56760

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0DataRank · unranked

20 citations

Kyoungmi Lee, Sehee Cho, Eun Ae Ko, Jihyun Kim, Sujin Jung +5 more

Deubiquitinating Enzyme USP8 Is Essential for Skeletogenesis by Regulating Wnt Signaling

International Journal of Molecular Sciences(2021)10.3390/ijms221910289

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0DataRank · unranked

16 citations

Jung‐Min Kim, Yeon-Suk Yang, Klaus‐Peter Knobeloch, Xi He, Jae‐Hyuck Shim +1 more

WNT-modulating gene silencers as a gene therapy for osteoporosis, bone fracture, and critical-sized bone defects

Molecular Therapy(2022)10.1016/j.ymthe.2022.09.018

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0DataRank · unranked

71 citations

Yeon-Suk Yang, Jun Xie, Hong Ma, Jung‐Min Kim, Kwang Hwan Park +6 more

Suppression of heterotopic ossification in fibrodysplasia ossificans progressiva using AAV gene delivery

Nature Communications(2022)10.1038/s41467-022-33956-9

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0DataRank · unranked

42 citations

Jung‐Min Kim, Jun Xie, Sachin Chaugule, Chujiao Lin, Hong Ma +8 more

Impaired mitochondrial oxidative metabolism in skeletal progenitor cells leads to musculoskeletal disintegration

Nature Communications(2022)10.1038/s41467-022-34694-8

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0DataRank · unranked

42 citations

Qiyuan Yang, Dongsheng Guo, Jun Xie, Yeon-Suk Yang, Sachin Chaugule +15 more

AAV-mediated delivery of osteoblast/osteoclast-regulating miRNAs for osteoporosis therapy

Molecular Therapy — Nucleic Acids(2022)10.1016/j.omtn.2022.07.008

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0DataRank · unranked

32 citations

Jun Xie, Yeon-Suk Yang, Jung‐Min Kim, Chujiao Lin, Hong Ma +3 more

The Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Pathway in Osteoblasts

Journal of Bone Metabolism(2022)10.11005/jbm.2022.29.1.1

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0DataRank · unranked

31 citations

Jae‐Hyuck Shim, Seoyeon Bok, Jung‐Min Kim, Matthew B. Greenblatt

Regulation of sclerostin by the SIRT1 stabilization pathway in osteocytes

Cell Death and Differentiation(2022)10.1038/s41418-022-00952-x

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0DataRank · unranked

25 citations

Yeon-Suk Yang, Jun Xie, Oksun Lee, JiHea Kim, Jaehyoung Hong +7 more

Suppression of Heterotopic Ossification in Fibrodysplasia Ossificans Progressiva Using AAV Gene Delivery

Research Square(2022)10.21203/rs.3.rs-1646941/v1

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0DataRank · unranked

3 citations

Jung‐Min Kim, Jun Xie, Sachin Chaugule, Chujiao Lin, H. Ma +8 more

Impaired ERK MAPK activation in mature osteoblasts enhances bone formation via the mTOR pathway

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.24.477465

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0DataRank · unranked

1 citations

Yeon-Suk Yang, Jaehyoung Hong, Sachin Chaugule, Hyonho Chun, Marjolein C. H. van der Meulen +4 more

Schnurri-3 inhibition suppresses bone and joint damage in models of rheumatoid arthritis

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2218019120

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0DataRank · unranked

28 citations

Jung‐Min Kim, Yeon-Suk Yang, Kerstin Nündel, Sachin Chaugule, Tadatoshi Sato +5 more

AAV-based gene editing of type 1 collagen mutation to treat osteogenesis imperfecta

Molecular Therapy — Nucleic Acids(2023)10.1016/j.omtn.2023.102111

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0DataRank · unranked

20 citations

Tadatoshi Sato, Sachin Chaugule, Hong Mā, Jun Xie, Guangping Gao +2 more

An angiogenic approach to osteoanabolic therapy targeting the SHN3-SLIT3 pathway

Bone(2023)10.1016/j.bone.2023.116761

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0DataRank · unranked

16 citations

Jae‐Hyuck Shim, Ren Xu, Matthew B. Greenblatt, Alisha R. Yallowitz

Sensors in Bone: Technologies, Applications, and Future Directions

Sensors(2024)10.3390/s24196172

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0DataRank · unranked

13 citations

Taruneet Kaur, Sachin Chaugule, Yeon-Suk Yang, Aryan Mago, Jae‐Hyuck Shim +2 more

Engineering a targeted and safe bone anabolic gene therapy to treat osteoporosis in alveolar bone loss

Molecular Therapy(2024)10.1016/j.ymthe.2024.06.036

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0DataRank · unranked

12 citations

Yeon-Suk Yang, H. Ma, Zhihao Chen, Dong Chen, Aijaz Ahmad John +4 more

Advances in Bone-Targeting Drug Delivery: Emerging Strategies Using Adeno-Associated Virus

Human Gene Therapy(2024)10.1089/hum.2024.034

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0DataRank · unranked

4 citations

Sachin Chaugule, Matthew B. Greenblatt, Guangping Gao, Jae‐Hyuck Shim, Tadatoshi Sato

Nucleic Acid Aptamers Protect Against Lead (Pb(II)) Toxicity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.28.587288

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0DataRank · unranked

0 citations

Solimar Ramis De Ayreflor Reyes, Aijaz Ahmad John, Erik Breiling, Abigail M. O’Connor, Stéphanie Reis +5 more

Author response: The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence

(2024)10.7554/elife.101984.1.sa0

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0DataRank · unranked

0 citations

Yuan Wang, Luyang Zhang, Chunjie Wang, Deping Chen, Haibo Liu +5 more

Nature-inspired IL-1 targeted therapy to treat chronic inflammatory diseases

Molecular Therapy(2025)10.1016/j.ymthe.2025.09.008

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0DataRank · unranked

4 citations

Mi‐Jeong Kim, Sachin Chaugule, Emma Mayer, Ngoc DeSouza, Hong Ma +7 more

The Growing Significance of microRNAs in Osteoporosis

Cells(2025)10.3390/cells14231905

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0DataRank · unranked

4 citations

Sana Sarkar, Afreen Anwar, Ji Woong Kim, Jae‐Hyuck Shim, Aijaz Ahmad John +1 more

Potent and durable gene modulation in heart and muscle with chemically defined lipophilic siRNAs

Nucleic Acids Research(2025)10.1093/nar/gkaf1374

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0DataRank · unranked

1 citations

Clemens Lochmann, Rosemary Gagnon, Ashley Summers, Jillian Caiazzi, Julianna Buchwald +15 more

A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation

Nature Communications(2020)10.1038/s41467-020-16038-6

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0DataRank · unranked

98 citations

Yeon-Suk Yang, Kwang Hwan Park, Xianpeng Ge, Ren Xu, Na Li +14 more