Paul C. Trippier

Also affiliated with Susan Thompson Buffett Foundation, Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 24 papers. Top paper: “Discovery of Halogenated Benzothiadiazine Derivatives with Anticancer Activity**”.

Discovery of Halogenated Benzothiadiazine Derivatives with Anticancer Activity**

ChemMedChem(2020)10.1002/cmdc.202000729

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12 citations

Myla Bhakta, Chaitanya A. Kulkarni, Alexander S. Milliken, Feifei Wang, Aimin Peng +3 more

Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer

European Journal of Medicinal Chemistry(2020)10.1016/j.ejmech.2020.112866

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17 citations

Sadisna Shahi, Racheal G. Akwii, Md Sanaullah Sajib, Mohammad Jodeiri Farshbaf, Raja Reddy Kallem +8 more

Discovery of Halogenated Benzothiadiazine Derivatives with Anticancer Activity

ChemRxiv(2020)10.26434/chemrxiv.12350912.v2

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1 citations

Myla Bhakta, Chaitanya Kulkarni, Alexander S. Milliken, Feifei Wang, Aimin Peng +3 more

The Current State of Drug Repurposing and Rare Diseases: an Interview With Paul Trippier

Future Drug Discovery(2020)10.4155/fdd-2019-0037

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0 citations

Paul C. Trippier

Discovery of Halogenated Benzothiadiazine Derivatives with Anticancer Activity

(2020)10.26434/chemrxiv.12350912.v1

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0 citations

Myla Bakta, Chaitanya A. Kulkarni, Alexander S. Milliken, Feifei Wang, Aimin Peng +3 more

Small Molecules that Rescue Multiple Phenotypic Aberrations in an iPSC-Derived Neuron Model of CLN3 Disease

ChemRxiv(2020)10.26434/chemrxiv.11493132

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0 citations

A. Morsy, Ronak Patel, Angelica V. Carmona, Md Sanaullah Sajib, Snehal Raut +4 more

Discovery of Halogenated Benzothiadiazine Derivatives with Anticancer Activity

ChemRxiv(2020)10.26434/chemrxiv.12350912

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0 citations

Myla Bhakta, Chaitanya A. Kulkarni, Alexander S. Milliken, Feifei Wang, Aimin Peng +3 more

Aldo-Keto Reductases and Cancer Drug Resistance

Pharmacological Reviews(2021)10.1124/pharmrev.120.000122

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139 citations

Sravan K. Jonnalagadda, Paul C. Trippier, Tea Lanišnik Rižner, T.M. Penning

In-Vivo and Ex-Vivo Brain Uptake Studies of Peptidomimetic Neurolysin Activators in Healthy and Stroke Animals

Pharmaceutical Research(2022)10.1007/s11095-022-03218-w

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12 citations

Shiva Hadi Esfahani, Behnam Noorani, Dhaval Patel, Heidi Villalba, Yashwardhan Ghanwatkar +7 more

Structure-activity relationship studies of functionalized aromatic peptidomimetics as neurolysin activators

Bioorganic & Medicinal Chemistry Letters(2022)10.1016/j.bmcl.2022.128669

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7 citations

Shiva Hadi Esfahani, Saeideh Nozohouri, Shikha Kumari, Joanna Kocot, Yong Zhang +4 more

Chlorinated benzothiadiazines inhibit angiogenesis through suppression of VEGFR2 phosphorylation

Bioorganic & Medicinal Chemistry(2022)10.1016/j.bmc.2022.116805

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6 citations

Sravan K. Jonnalagadda, Shirisha Jonnalagadda, Fatema Tuz Zahra, Alessio Nocentini, Claudiu T. Supuran +3 more

The evolution of small molecule enzyme activators

RSC Medicinal Chemistry(2023)10.1039/d3md00399j

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24 citations

Alfie M. Case, Megan P. Paustian, Braeden Pinkerton, Princess Simeon, Paul C. Trippier +1 more

Selective carbonic anhydrase IX and XII inhibitors based around a functionalized coumarin scaffold

Drug Development Research(2023)10.1002/ddr.22049

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13 citations

Sravan K. Jonnalagadda, Shirisha Jonnalagadda, Shikha Kumari, Alessio Nocentini, Claudiu T. Supuran +2 more

Discovery of the Next Generation of Non-peptidomimetic Neurolysin Activators with High Blood-Brain Barrier Permeability: a Pharmacokinetics Study in Healthy and Stroke Animals

Pharmaceutical Research(2023)10.1007/s11095-023-03619-5

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6 citations

Sejal Sharma, Shirisha Jonnalagadda, Shikha Kumari, Aarfa Queen, Shiva Hadi Esfahani +7 more

Studies on diketopiperazine and dipeptide analogs as opioid receptor ligands

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115309

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10 citations

Mohammad Anwar Hossain, Guangchen Ji, Sravan K. Jonnalagadda, Samuel Obeng, Md. Ashrafur Rahman +14 more

Aldo-Keto Reductase 1C3 Inhibitor Prodrug Improves Pharmacokinetic Profile and Demonstrates In Vivo Efficacy in a Prostate Cancer Xenograft Model

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c00732

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10 citations

Sravan K. Jonnalagadda, Ahmed Morsy, Ling Duan, Yashpal S. Chhonker, Daryl J. Murry +3 more

High brain-blood barrier permeability highlights a new class of neurolysin activators as promising candidates for stroke treatment: a pilot pharmacokinetic study in mice

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.122.533120

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0 citations

Sejal Sharma, Shiva Hadi Esfahani, Shirisha Jonnalagadda, Aarfa Queen, Saeideh Nozohouri +5 more

Discovery of an Aldo-Keto reductase 1C3 (AKR1C3) degrader

Communications Chemistry(2024)10.1038/s42004-024-01177-4

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13 citations

Shirisha Jonnalagadda, Alfie M. Case, Maddeboina Krishnaiah, Sravan K. Jonnalagadda, Louise F. Dow +4 more

Synthesis and biological characterization of a 17β hydroxysteroid dehydrogenase type 10 (17β-HSD10) inhibitor

RSC Medicinal Chemistry(2024)10.1039/d4md00733f

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1 citations

Rasangi Pathirage, Helen Erickson, Edrees Amani, Donald R. Ronning, Paul C. Trippier +1 more

Coumarin‐Based Aldo‐Keto Reductase Family 1C (AKR1C) 2 and 3 Inhibitors

ChemMedChem(2024)10.1002/cmdc.202400081

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4 citations

Ling Duan, Louise F. Dow, Geetha P. Boligala, Elizabeth A. Kosmacek, Kristyn McCoy +8 more

Synthesis and Biological Characterization of a 17β Hydroxysteroid Dehydrogenase Type 10 (17β-HSD10) Inhibitor

ChemRxiv(2024)10.26434/chemrxiv-2024-5jfcv

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1 citations

Rasangi Pathirage, Edrees Amani, Donald R. Ronning, Paul C. Trippier, Louise F. Dow

Synthesis and Biological Characterization of a 17β Hydroxysteroid Dehydrogenase Type 10 (17β-HSD10) Inhibitor

ChemRxiv(2024)10.26434/chemrxiv-2024-5jfcv-v2

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1 citations

Rasangi Pathirage, Edrees Amani, Donald R. Ronning, Paul C. Trippier, Louise F. Dow

Functionalized 1H-benzo[d]imidazoles that Confer Protective Effects in a Phenotypic CLN3 Disease Patient-Derived iPSC Model

ChemRxiv(2025)10.26434/chemrxiv-2025-hn6sj

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0 citations

Ramu Venkatesan, Xiaoyu Hao, Angelica V. Carmona, Sohel Daria, Yazen Alnouti +2 more

Protocol for screening of small molecules in a CLN3 disease patient-specific iPSC-derived neuronal progenitor cell model

STAR Protocols(2025)10.1016/j.xpro.2025.104269

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0 citations

Paul C. Trippier, Ramu Venkatesan