Derek M. Dykxhoorn

Also affiliated with Dr. John T. Macdonald Foundation

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 5%percentile

0.428Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

The natural history and genotype–phenotype correlations of TMPRSS3 hearing loss: an international, multi-center, cohort analysis

Human Genetics(2024)10.1007/s00439-024-02648-3

Top 43%

0.428DataRank

Top 43%7 citations

Cris Lanting, Molly Smeal, Susan H. Blanton, Derek M. Dykxhoorn, Pei-Ciao Tang +75 more

Papers

Driven by 38 papers — median percentile 57. Top paper: “Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds”.

Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds

Alzheimer s & Dementia(2021)10.1002/alz.12287

N/A

0.680DataRank · unranked

92 citations

Katrina Celis, Parker L. Bussies, Farid Rajabli, Patrice L. Whitehead, Kara L. Hamilton‐Nelson +19 more

The natural history and genotype–phenotype correlations of TMPRSS3 hearing loss: an international, multi-center, cohort analysis

Human Genetics(2024)10.1007/s00439-024-02648-3

Top 43%

0.428DataRank

Top 43%7 citations

Cris Lanting, Molly Smeal, Susan H. Blanton, Derek M. Dykxhoorn, Pei-Ciao Tang +75 more

Cognitive predictors of everyday functioning in women with HIV: findings from the women’s interagency HIV study

BMC Neurology(2025)10.1186/s12883-025-04249-7

N/A

0.290DataRank · unranked

5 citations

Lang Lang, Pauline M. Maki, Danyang Yu, Raha Dastgheyb, Yuezhe Wang +12 more

Converging evidence for differential regulatory control of APOEε4 on African versus European haplotypes

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.23.457375

N/A

0.104DataRank · unranked

1 citations

Marina Lipkin, Liyong Wang, Derek Van Booven, Antony J. Griswold, Farid Rajabli +16 more

βPix sequesters IDOL and prevents LDL receptor degradation through a β 2 AR-regulated signaling pathway in Alport Syndrome

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.06.372292

N/A

0DataRank · unranked

0 citations

Keyvan Yousefi, José Manuel Cóndor Capcha, Camila Iansen Irion, Guerline Lambert, Serene A. Shehadeh +15 more

Stem Cells and Gene Therapy in Progressive Hearing Loss: the State of the Art

Journal of the Association for Research in Otolaryngology(2021)10.1007/s10162-020-00781-0

N/A

0DataRank · unranked

27 citations

Brett Colbert, Eric S. Nisenbaum, A. Amraoui, Derek M. Dykxhoorn, Karl R. Koehler +3 more

Usher Syndrome in the Inner Ear: Etiologies and Advances in Gene Therapy

International Journal of Molecular Sciences(2021)10.3390/ijms22083910

N/A

0DataRank · unranked

27 citations

Brett Colbert, Pei-Ciao Tang, Byron L. Lam, Jun Yang, Susan H. Blanton +3 more

Regulation of Neural Circuit Development by Cadherin-11 Provides Implications for Autism

eNeuro(2021)10.1523/eneuro.0066-21.2021

N/A

0DataRank · unranked

22 citations

Robert F. Niescier, Morgan S. Bridi, Madel Durens, Jonathan E. Nestor, Michaela B. C. Kilander +7 more

Generation of hiPSC line UMi030-A from an individual with the hearing loss-related GJB2 mutation c.109G > A

Stem Cell Research(2021)10.1016/j.scr.2021.102599

N/A

0DataRank · unranked

3 citations

Nicholas Gosstola, Derek M. Dykxhoorn, Xue Zhong Liu, Brett Colbert

Characterization of UMi031-A-2 inducible pluripotent stem cell line with a neurofibromatosis type 2-associated mutation

Stem Cell Research(2021)10.1016/j.scr.2021.102474

N/A

0DataRank · unranked

5 citations

Nicholas Gosstola, Cristina Fernández‐Valle, Derek M. Dykxhoorn, Xue Zhong Liu, Aida Nourbakhsh

Derivation of iPSC line UMi029-A bearing a hearing-loss associated variant in the SMPX gene

Stem Cell Research(2021)10.1016/j.scr.2021.102405

N/A

0DataRank · unranked

2 citations

Xiaoying Tong, Nicholas Gosstola, Xue Zhong Liu, Derek M. Dykxhoorn

A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer’s Disease in African Ancestry

PLoS Genetics(2022)10.1371/journal.pgen.1009977

N/A

0DataRank · unranked

65 citations

Gary W. Beecham, Hugh C. Hendrie, Olusegun Baiyewu, Adesola Ogunniyi, Sujuan Gao +21 more

Genomic, transcriptomic, and metabolomic profiles of hiPSC-derived dopamine neurons from clinically discordant brothers with identical PRKN deletions

npj Parkinson s Disease(2022)10.1038/s41531-022-00346-3

N/A

0DataRank · unranked

12 citations

Hyunjin Kim, Anthony J. Griswold, Simona G. Codreanu, Lisa M. Prince, Stacy D. Sherrod +7 more

Transcriptomic analysis of isolated and pooled human postmortem cerebellar Purkinje cells in autism spectrum disorders

Frontiers in Genetics(2022)10.3389/fgene.2022.944837

N/A

0DataRank · unranked

11 citations

Anthony J. Griswold, Derek J. Van Booven, Michaela B. C. Kilander, Jeannine A. Frei, Michael W. Nestor +4 more

Brain endothelium-derived extracellular vesicles containing amyloid-beta induce mitochondrial alterations in neural progenitor cells

Extracellular Vesicles and Circulating Nucleic Acids(2022)10.20517/evcna.2022.22

N/A

0DataRank · unranked

11 citations

J Kowalczyk, Kelssey D Pierre Louis, Manav Daftari, Brett Colbert, Oandy Naranjo +5 more

Downregulation of SOCS1 increases interferon-induced ISGylation during differentiation of induced-pluripotent stem cells to hepatocytes

JHEP Reports(2022)10.1016/j.jhepr.2022.100592

N/A

0DataRank · unranked

7 citations

Stephanie A Delabat, Alejandro D. Badilla, Robert C. DiCaprio, Jinhee Hyun, R. Alan Burgess +8 more

Characterization of an induced pluripotent stem cell line (UMi040-A) bearing an auditory neuropathy spectrum disorder-associated variant in TMEM43

Stem Cell Research(2022)10.1016/j.scr.2022.102758

N/A

0DataRank · unranked

3 citations

Marie Valerie Roche, Se Young Um, Nicholas Gosstola, Min Young Kim, Byung Yoon Choi +3 more

Ancestry-related differences in chromatin accessibility and gene expression of APOE4 are associated with Alzheimer disease risk

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.27.514114

N/A

0DataRank · unranked

0 citations

Maria DM. Muniz Moreno, Farid Rajabli, Patrice L. Whitehead, Kara L. Hamilton‐Nelson, Derek M. Dykxhoorn +15 more

Anti-amyloid: An antibody to cure Alzheimer’s or an attitude

iScience(2023)10.1016/j.isci.2023.107461

N/A

0DataRank · unranked

27 citations

Oandy Naranjo, Bradlee L. Heckmann, Derek M. Dykxhoorn, Michał Toborek, Olivia Osborne

Ancestry‐related differences in chromatin accessibility and gene expression of APOE ε4 are associated with Alzheimer's disease risk

Alzheimer s & Dementia(2023)10.1002/alz.13075

N/A

0DataRank · unranked

21 citations

Maria del Mar Muñiz Moreno, Farid Rajabli, Patrice L. Whitehead, Kara L. Hamilton‐Nelson, Derek M. Dykxhoorn +15 more

HIV Promotes Atherosclerosis via Circulating Extracellular Vesicle MicroRNAs

International Journal of Molecular Sciences(2023)10.3390/ijms24087567

N/A

0DataRank · unranked

10 citations

Jianqin Wei, Lukun Zhang, Conrad Macon, Bernard M. Degnan, Dushyantha Jayaweera +9 more

An Alzheimer’s disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons

Neurobiology of Aging(2023)10.1016/j.neurobiolaging.2023.07.007

N/A

0DataRank · unranked

8 citations

Carolina Duarte, Mayra Juliana Laverde-Paz, Shaina A. Simon, Derek J. Van Booven, Amanda T. Miyares +10 more

MicroRNA-423-5p Mediates Cocaine-Induced Smooth Muscle Cell Contraction by Targeting Cacna2d2

International Journal of Molecular Sciences(2023)10.3390/ijms24076584

N/A

0DataRank · unranked

4 citations

Huilan Wang, Andrea da Fonseca Ferreira, Jianqin Wei, Chunming Dong, Derek M. Dykxhoorn

An Alzheimer’s disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.25.542316

N/A

0DataRank · unranked

0 citations

Carolina Duarte, Mayra Juliana Laverde-Paz, Shaina A. Simon, Derek J. Van Booven, Amanda T. Miyares +10 more

Cognitive changes during the menopausal transition: a longitudinal study in women with and without HIV

UNC Libraries(2023)10.17615/ef3b-yn05

N/A

0DataRank · unranked

0 citations

K. Anastos, A.A. Adimora, Pauline M. Maki, D.R. Gustafson, Leah H. Rubin +7 more

Post-stroke hippocampal neurogenesis is impaired by microvascular dysfunction and PI3K signaling in cerebral amyloid angiopathy

Cell Reports(2024)10.1016/j.celrep.2024.114848

N/A

0DataRank · unranked

6 citations

Manav Daftari, Oandy Naranjo, Adarsh N. Johar, Samantha A. Brooks, Brett Colbert +14 more

Does cognitive intra-individual variability predict change in everyday functioning performance in women with and without HIV in the Women’s Interagency HIV Study?

Applied Neuropsychology Adult(2024)10.1080/23279095.2024.2444573

N/A

0DataRank · unranked

6 citations

Yanxun Xu, Raha Dastgheyb, Pauline M. Maki, J. Zhang, Gayle Springer +17 more

Lipophilic compounds restore function to neurodevelopmental-associated KCNQ3 mutations

Communications Biology(2024)10.1038/s42003-024-06873-4

N/A

0DataRank · unranked

4 citations

Andy Hinojo-Perez, Mekedlawit Efrem, Yi-Chun Lin, Iqra Shams, Sébastien Hayoz +7 more

Lipophilic compounds restore wt function of neurodevelopmental-associated KCNQ3 mutations

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.13.584879

N/A

0DataRank · unranked

0 citations

Andy Hinojo-Perez, Mekedlawit Efrem, Yi‐Chun Lin, Iqra Shams, Sébastien Hayoz +7 more

Interactions among Merlin, Arkadia, and SKOR2 mediate NF2-associated Schwann cell proliferation in human

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.24.614711

N/A

0DataRank · unranked

0 citations

Seyoung Um, Anderson B. Mayfield, Olena Bracho, Christian Castillo, Christine T. Dinh +3 more

Integrator promotes the association of TFIID and RNA polymerase II to maintain pluripotency during development

Molecular Cell(2025)10.1016/j.molcel.2025.07.006

N/A

0DataRank · unranked

3 citations

Felipe Beckedorff, Pradeep Reddy Cingaram, Saeid Mohammad Parast, Jingyin Yue, Gary LeRoy +14 more

Exploring potential mechanisms of an African protective locus for Alzheimer's disease in APOEε4 carriers

Alzheimer s & Dementia(2025)10.1002/alz.70500

N/A

0DataRank · unranked

3 citations

Karen Nuytemans, Derek J. Van Booven, Farid Rajabli, Sofia Moura, Aura M. Ramírez +17 more

Interactions among Merlin, Arkadia, and SKOR2 mediate NF2-associated human Schwann cell proliferation

Stem Cell Research & Therapy(2025)10.1186/s13287-025-04281-x

N/A

0DataRank · unranked

0 citations

Seyoung Um, Anderson B. Mayfield, Olena Bracho, Christian Castillo, Christine T. Dinh +3 more

Polyunsaturated fatty acid analogues differentially affect cardiac NaV, CaV, and KV channels through unique mechanisms

eLife(2020)10.7554/elife.51453

N/A

0DataRank · unranked

30 citations

Alicia de la Cruz, Xiaoan Wu, Jessica J. Jowais, Marta E. Perez, Derek M. Dykxhoorn +3 more

Generation of two isogenic induced pluripotent stem cell lines derived from a Hispanic individual with Alzheimer’s Disease and mosaic for loss of the Y chromosome

Stem Cell Research(2025)10.1016/j.scr.2025.103851

N/A

0DataRank · unranked

0 citations

Brooke A. DeRosa, Lauren Coombs, Eugene Tang, Denise R Leyva, Ainnara R. Lazzaro +8 more

Three Brothers With Autism Carry a Stop‐Gain Mutation in the HPA‐Axis Gene NR3C2

Autism Research(2020)10.1002/aur.2269

N/A

0DataRank · unranked

14 citations

Anthony J. Griswold, Natalia K. Hofmann, Lissette Gomez, Patrice L. Whitehead, Ruth K. Abramson +5 more

Long-range cis-regulatory elements controlling GDF6 expression are essential for ear development

Journal of Clinical Investigation(2020)10.1172/jci136951

N/A

0DataRank · unranked

18 citations

Clemer Abad, Filiz Başak Cengiz, Serhat Seyhan, Armağan İncesulu, Shengru Guo +14 more

Characterization of UMi028-A-1 stem cell line that contains a CRISPR/Cas9 induced hearing loss-associated variant (V60L (c.178G > T)) in the P2RX2 gene

Stem Cell Research(2020)10.1016/j.scr.2020.102017

N/A

0DataRank · unranked

1 citations

Zaohua Huang, Xiaoying Tong, Aida Nourbakhsh, Zheng‐Yi Chen, Derek M. Dykxhoorn +2 more

Derek M. Dykxhoorn

Indexed papers

Top data-sharing exemplar

Papers