Sabina Signoretti

Also affiliated with Harvard University, Dana-Farber Cancer Institute

MedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.646Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Progressive natural killer cell dysfunction in advanced-stage clear-cell renal cell carcinoma and association with clinical outcomes

ESMO Open(2025)10.1016/j.esmoop.2024.104105

Top 42%

0.448DataRank

Top 42%11 citations

G. G. Birch, Alia Meliki, V Moritz, Mausumi Bharadwaj, Nicholas R. Schindler +20 more

Papers

Driven by 54 papers — median percentile 35. Top paper: “Long-term outcomes with nivolumab plus ipilimumab versus sunitinib in first-line treatment of patients with advanced sarcomatoid renal cell carcinoma”.

Long-term outcomes with nivolumab plus ipilimumab versus sunitinib in first-line treatment of patients with advanced sarcomatoid renal cell carcinoma

Journal for ImmunoTherapy of Cancer(2022)10.1136/jitc-2022-005445

N/A

2.7DataRank · unranked

69 citations

Sabina Signoretti, Toni K. Choueiri, David F. McDermott, Robert J. Motzer, Saby George +9 more

Perioperative nivolumab versus observation in patients with renal cell carcinoma undergoing nephrectomy (PROSPER ECOG-ACRIN EA8143): an open-label, randomised, phase 3 study

The Lancet Oncology(2024)10.1016/s1470-2045(24)00211-0

N/A

1.9DataRank · unranked

86 citations

Se-Eun Kim, Viraj A. Master, David H. McDermott, Lauren C. Harshman, Suzanne Cole +40 more

Progressive natural killer cell dysfunction in advanced-stage clear-cell renal cell carcinoma and association with clinical outcomes

ESMO Open(2025)10.1016/j.esmoop.2024.104105

Top 42%

0.448DataRank

Top 42%11 citations

G. G. Birch, Alia Meliki, V Moritz, Mausumi Bharadwaj, Nicholas R. Schindler +20 more

Single cell transcriptomic characterization of natural killer (NK) cell populations in clear cell renal cell carcinoma and association with clinical outcomes.

Journal of Clinical Oncology(2022)10.1200/jco.2022.40.16_suppl.e16521

Top 65%

0.198DataRank

Top 65%2 citations

Maheetha Bharadwaj, Grace Birch, Nicholas Schindler, Chris Labaki, Renée Maria Saliby +13 more

pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner

UNC Libraries(2020)10.17615/792d-1w31

N/A

0DataRank · unranked

4 citations

Jinfang Zhang, Hiroyuki Inuzuka, Xingnan Zheng, Wenjian Gan, Abhishek A. Chakraborty +13 more

Evaluation of predictive biomarkers for nivolumab in patients (pts) with metastatic clear cell renal cell carcinoma (mccRCC) from the CheckMate-025 (CM-025) trial.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.5023

N/A

0DataRank · unranked

12 citations

Opeyemi A. Jegede, Miriam Sant’Angelo, Sonia Moreno, David A. Braun, Megan Wind‐Rotolo +15 more

PROSPER: Phase III randomized study comparing perioperative nivolumab versus observation in patients with renal cell carcinoma (RCC) undergoing nephrectomy (ECOG-ACRIN EA8143).

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.tps5101

N/A

0DataRank · unranked

8 citations

Mäneka Puligandla, Mohamad E. Allaf, David F. McDermott, Charles G. Drake, Sabina Signoretti +15 more

Integrative Molecular Characterization of Sarcomatoid and Rhabdoid Renal Cell Carcinoma Reveals Determinants of Poor Prognosis and Response to Immune Checkpoint Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.28.121806

N/A

0DataRank · unranked

3 citations

David A. Braun, Sachet A. Shukla, Wenting Pan, Xīn Gào, Yue Hou +47 more

Immunogenomic characterization of advanced clear cell renal cell carcinoma treated with PD-1 blockade.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.5010

N/A

0DataRank · unranked

2 citations

Yue Hou, Ziad Bakouny, Miriam Ficial, Miriam Sant’Angelo, Petra Ross‐Macdonald +15 more

The Somatic Genomic Landscape of Chromophobe Renal Cell Carcinoma

UNC Libraries(2020)10.17615/bd0j-6b91

N/A

0DataRank · unranked

0 citations

Kristen M. Leraas, Angela B. Smith, Michael J. Seiler, A. B. Clarke, Mark A. Jensen +95 more

Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion

UNC Libraries(2020)10.17615/wq19-7x17

N/A

0DataRank · unranked

0 citations

Adam J. Bass, Alex H. Ramos, Yujin Hoshida, Andrey Sivachenko, Trevor J. Pugh +27 more

Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine

UNC Libraries(2020)10.17615/emqc-jb75

N/A

0DataRank · unranked

0 citations

Kimberly J. Briggs, Agnieszka K. Witkiewicz, Shugeng Cao, Benjamin F. Cravatt, Keriann M. Backus +9 more

The landscape of somatic copy-number alteration across human cancers

PMC(2020)10.17615/gvhn-9a16

N/A

0DataRank · unranked

0 citations

Michael S. Lawrence, Ted Liefeld, Michael R. Reich, Rameen Beroukhim, Reid M. Pinchback +27 more

Progressive immune dysfunction with advancing disease stage in renal cell carcinoma

Cancer Cell(2021)10.1016/j.ccell.2021.02.013

N/A

0DataRank · unranked

525 citations

Kelly Street, Kelly P. Burke, David L. Cookmeyer, Thomas Denize, Christina B. Pedersen +30 more

Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma

Nature Communications(2021)10.1038/s41467-021-21068-9

N/A

0DataRank · unranked

169 citations

David A. Braun, Sachet A. Shukla, Wenting Pan, Xīn Gào, Yue Hou +48 more

A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes

Clinical Cancer Research(2021)10.1158/1078-0432.ccr-21-0121

N/A

0DataRank · unranked

48 citations

Miriam Ficial, Caroline S. Jansen, Taghreed Hirz, Luke del Balzo, Scott Wilkinson +12 more

Plasticity in the Absence of NOTCH Uncovers a RUNX2-Dependent Pathway in Small Cell Lung Cancer

Cancer Research(2021)10.1158/0008-5472.can-21-1991

N/A

0DataRank · unranked

42 citations

Erik H. Knelson, Yixiang Li, Yavuz T. Durmaz, Wenhua Gao, Emily Walton +14 more

BRCA1/Trp53 heterozygosity and replication stress drive esophageal cancer development in a mouse model

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2108421118

N/A

0DataRank · unranked

11 citations

Joshua Rivera, Miklós Dióssy, Haohui Duan, Christian Bowman-Colin, Rachel Reed +13 more

De Novo Pyrimidine Synthesis is a Targetable Vulnerability in IDH Mutant Glioma

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.30.470443

N/A

0DataRank · unranked

11 citations

Milan R. Savani, Michael M. Levitt, Adam C. Wang, Jennifer E. Endress, Cylaina Bird +38 more

PROSPER: Phase III RandOmized Study Comparing PERioperative nivolumab versus observation in patients with renal cell carcinoma (RCC) undergoing nephrectomy (ECOG-ACRIN EA8143).

Journal of Clinical Oncology(2021)10.1200/jco.2021.39.15_suppl.tps4596

N/A

0DataRank · unranked

10 citations

Se Eun Kim, Viraj A. Master, David F. McDermott, Sabina Signoretti, David Cella +15 more

A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes

medRxiv(2021)10.1101/2021.01.27.21250464

N/A

0DataRank · unranked

4 citations

Miriam Ficial, Caroline S. Jansen, Taghreed Hirz, Luke del Balzo, Scott Wilkinson +12 more

Regulation of Neuroendocrine Plasticity by the RNA-Binding Protein ZFP36L1

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.22.465501

N/A

0DataRank · unranked

4 citations

Yavuz T. Durmaz, Yixiang Li, Amin H. Sabet, Amir Vajdi, Thomas Denize +11 more

De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma

Cancer Cell(2022)10.1016/j.ccell.2022.07.011

N/A

0DataRank · unranked

131 citations

Milan R. Savani, Michael M. Levitt, Adam C. Wang, Jennifer E. Endress, Cylaina Bird +46 more

Integrative clinical and molecular characterization of translocation renal cell carcinoma

Cell Reports(2022)10.1016/j.celrep.2021.110190

N/A

0DataRank · unranked

118 citations

Ananthan Sadagopan, Praful Ravi, Nebiyou Y. Metaferia, Jiao Li, Shatha AbuHammad +35 more

Regulation of neuroendocrine plasticity by the RNA-binding protein ZFP36L1

Nature Communications(2022)10.1038/s41467-022-31998-7

N/A

0DataRank · unranked

42 citations

Yavuz T. Durmaz, Yixiang Li, Amin H. Sabet, Amir Vajdi, Thomas Denize +12 more

Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer

Molecular Cancer Research(2022)10.1158/1541-7786.mcr-21-0322

N/A

0DataRank · unranked

14 citations

Yubao Wang, Caroline F. Ribeiro, Cherubin Manokaran, Hyeyoun Chang, Thanh Von +17 more

KDM6A epigenetically regulates subtype plasticity in small cell lung cancer

Nature Cell Biology(2023)10.1038/s41556-023-01210-z

N/A

0DataRank · unranked

69 citations

Yixiang Li, Matthew A. Booker, Yingtian Xie, Sarah Naomi Olsen, Radhika A. Patel +19 more

Spatially aware deep learning reveals tumor heterogeneity patterns that encode distinct kidney cancer states

Cell Reports Medicine(2023)10.1016/j.xcrm.2023.101189

N/A

0DataRank · unranked

39 citations

Thomas Denize, Ziad Bakouny, Chris Labaki, Breanna M. Titchen, Kevin Bi +13 more

PD-1 Expression on Intratumoral Regulatory T Cells Is Associated with Lack of Benefit from Anti–PD-1 Therapy in Metastatic Clear-Cell Renal Cell Carcinoma Patients

Clinical Cancer Research(2023)10.1158/1078-0432.ccr-23-2274

N/A

0DataRank · unranked

37 citations

Opeyemi A. Jegede, Sayed Matar, Nourhan El Ahmar, Destiny J. West, Emily Walton +16 more

Epigenomic charting and functional annotation of risk loci in renal cell carcinoma

Nature Communications(2023)10.1038/s41467-023-35833-5

N/A

0DataRank · unranked

34 citations

Sarah Abou Alaiwi, Sylvan C. Baca, Elio Adib, Rosario I. Corona, Ji-Heui Seo +31 more

Combinatorial biomarker for predicting outcomes to anti-PD-1 therapy in patients with metastatic clear cell renal cell carcinoma

Cell Reports Medicine(2023)10.1016/j.xcrm.2023.100947

N/A

0DataRank · unranked

27 citations

Evan J. Lipson, Ludmila Danilova, Suzanne L. Topalian, Jaroslaw Jedrych, Ezra Baraban +10 more

Regulation of HHLA2 expression in kidney cancer and myeloid cells

BMC Cancer(2023)10.1186/s12885-023-11496-9

N/A

0DataRank · unranked

7 citations

Nahuel Perrot, Zimo Huang, Rupal S. Bhatt, Aseman Sheshdeh Bagheri, Nourhan El Ahmar +6 more

Core biopsy (bx) accuracy and safety of biopsy and preoperative immunotherapy in predicting histological subtype and nuclear grade in ECOG-ACRIN EA8143 perioperative nivolumab (nivo) versus observation in patients (pts) with renal cell carcinoma (RCC) undergoing nephrectomy.

Journal of Clinical Oncology(2023)10.1200/jco.2023.41.16_suppl.4541

N/A

0DataRank · unranked

1 citations

Se Eun Kim, David F. McDermott, Viraj A. Master, Sabina Signoretti, Mahmut Akgül +13 more

Data from A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes

(2023)10.1158/1078-0432.c.6530387

N/A

0DataRank · unranked

0 citations

Miriam Ficial, Caroline S. Jansen, Taghreed Hirz, Luke del Balzo, Scott Wilkinson +12 more

Data from A Subset of Localized Prostate Cancer Displays an Immunogenic Phenotype Associated with Losses of Key Tumor Suppressor Genes

(2023)10.1158/1078-0432.c.6530387.v1

N/A

0DataRank · unranked

0 citations

Miriam Ficial, Caroline S. Jansen, Taghreed Hirz, Luke del Balzo, Scott Wilkinson +12 more

Data from Plasticity in the Absence of NOTCH Uncovers a RUNX2-Dependent Pathway in Small Cell Lung Cancer

(2023)10.1158/0008-5472.c.6513738.v1

N/A

0DataRank · unranked

0 citations

Erik H. Knelson, Yixiang Li, Yavuz T. Durmaz, Wenhua Gao, Emily Walton +14 more

Data from Efficacy and Safety of Nivolumab Plus Ipilimumab versus Sunitinib in First-line Treatment of Patients with Advanced Sarcomatoid Renal Cell Carcinoma

(2023)10.1158/1078-0432.c.6529871

N/A

0DataRank · unranked

0 citations

Sabina Signoretti, Toni K. Choueiri, David F. McDermott, Robert J. Motzer, Abdallah Flaifel +19 more

Data from Mutations and Response to Rapalogs in Patients with Metastatic Renal Cell Carcinoma

(2023)10.1158/1535-7163.c.6542307

Top 100%

0DataRank

Top 100%0 citations

Lana Hamieh, Kathryn P. Gray, Aaron R. Thorner, André P. Fay, Kathryn D. Lasseter +8 more

Data from KIR3DL3 Is an Inhibitory Receptor for HHLA2 that Mediates an Alternative Immunoinhibitory Pathway to PD1

(2023)10.1158/2326-6066.c.6550380

N/A

0DataRank · unranked

0 citations

Abdulla Berjis, Julie C. Konge, Kathleen M. Mahoney, Alyssa N. Klee, Samuel S. Freeman +14 more

Data from KIR3DL3 Is an Inhibitory Receptor for HHLA2 that Mediates an Alternative Immunoinhibitory Pathway to PD1

(2023)10.1158/2326-6066.c.6550380.v1

N/A

0DataRank · unranked

0 citations

Abdulla Berjis, Julie C. Konge, Kathleen M. Mahoney, Alyssa N. Klee, Samuel S. Freeman +14 more

A pathology foundation model for cancer diagnosis and prognosis prediction

Nature(2024)10.1038/s41586-024-07894-z

N/A

0DataRank · unranked

457 citations

Junhan Zhao, Eliana Marostica, Wei Yuan, Jietian Jin, Jiayu Zhang +24 more

Impact of renal cell carcinoma molecular subtypes on immunotherapy and targeted therapy outcomes

Cancer Cell(2024)10.1016/j.ccell.2024.03.002

N/A

0DataRank · unranked

46 citations

Chris Labaki, Tejas Jammihal, Wanling Xie, Maxine Sun, Valisha Shah +19 more

Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma

Cell Reports(2024)10.1016/j.celrep.2024.114350

N/A

0DataRank · unranked

29 citations

Karl Semaan, Marc Eid, Ji-Heui Seo, Simon Garinet, Matthew P. Davidsohn +34 more

Toward a CRISPR-based mouse model of Vhl -deficient clear cell kidney cancer: Initial experience and lessons learned

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2408549121

N/A

0DataRank · unranked

10 citations

Wenhua Gao, Laura S. Schmidt, Kevin Bi, C. Ricketts, Vijyendra Ramesh +28 more

Presence of Tertiary Lymphoid Structures and Exhausted Tissue-Resident T Cells Determines Clinical Response to PD-1 Blockade in Renal Cell Carcinoma

Cancer Discovery(2025)10.1158/2159-8290.cd-24-0991

N/A

0DataRank · unranked

38 citations

Lena V. Wirth, Kelly Street, Neil Ruthen, Opeyemi A. Jegede, Nicholas R. Schindler +22 more

Updated pan-tumor guidelines for neoadjuvant scoring of pathologic response: a joint SITC and INMC effort

Annals of Oncology(2025)10.1016/j.annonc.2025.10.018

N/A

0DataRank · unranked

8 citations

Richard A. Scolyer, Elizabeth M. Burton, Klaus J. Busam, Kuang Yu Chen, Ashley Cimino‐Mathews +18 more

The SLC1A1/EAAT3 dicarboxylic amino acid transporter is an epigenetically dysregulated nutrient carrier that sustains oncogenic metabolic programs

Nature Communications(2025)10.1038/s41467-025-64983-x

N/A

0DataRank · unranked

4 citations

Pooneh Koochaki, Sayed Matar, Fatme Ghandour, Marc Machaalani, Eddy Saad +22 more

Integrative clinical, genomic, and transcriptomic characterization of circulating KIM-1 in metastatic RCC.

Journal of Clinical Oncology(2025)10.1200/jco.2025.43.16_suppl.4546

N/A

0DataRank · unranked

0 citations

Renée Maria Saliby, Eddy Saad, Clara Steiner, Caiwei Zhong, Emre Yekedüz +15 more

Pan-cancer prediction of tumor immune activation and response to immune checkpoint blockade from tumor transcriptomics and histopathology

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.27.661875

N/A

0DataRank · unranked

0 citations

Sumeet Patiyal, Lipika R. Pal, Tiangen Chang, Sumona Biswas, Saugato Rahman Dhruba +36 more

Efficacy and Safety of Nivolumab Plus Ipilimumab versus Sunitinib in First-line Treatment of Patients with Advanced Sarcomatoid Renal Cell Carcinoma

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-20-2063

N/A

0DataRank · unranked

243 citations

Sabina Signoretti, Toni K. Choueiri, David F. McDermott, Robert J. Motzer, Abdallah Flaifel +19 more

Presence of tertiary lymphoid structures and exhausted tissue-resident T cells determines clinical response to PD-1 blockade in renal cell carcinoma 3574

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.1362

N/A

0DataRank · unranked

0 citations

Miya B. Hugaboom, Kelly Street, Neil Ruthen, Opeyemi A. Jegede, Nicholas R. Schindler +22 more

KIR3DL3 Is an Inhibitory Receptor for HHLA2 that Mediates an Alternative Immunoinhibitory Pathway to PD1

Cancer Immunology Research(2020)10.1158/2326-6066.cir-20-0315

N/A

0DataRank · unranked

113 citations

Abdulla Berjis, Julie C. Konge, Kathleen M. Mahoney, Alyssa N. Klee, Samuel S. Freeman +14 more

Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors

Cancer Immunology Research(2020)10.1158/2326-6066.cir-19-0866

N/A

0DataRank · unranked

79 citations

Amin H. Nassar, Wanling Xie, Ziad Bakouny, Jacob E. Berchuck, David A. Braun +27 more

Summary From the First Kidney Cancer Research Summit, September 12–13, 2019: A Focus on Translational Research

JNCI Journal of the National Cancer Institute(2020)10.1093/jnci/djaa064

N/A

0DataRank · unranked

40 citations

Michael B. Atkins, Ziad Bakouny, Maria I. Carlo, Charles G. Drake, Eric Jonasch +15 more

Sabina Signoretti

Indexed papers

Top data-sharing exemplar

Papers