Alain Laederach

University of North Carolina at Chapel Hill

Also affiliated with Discovery Place, Segeberger Kliniken, UNC Lineberger Comprehensive Cancer Center

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 50 papers. Top paper: “Toward interoperable bioscience data”.

Toward interoperable bioscience data

Nature Genetics(2012)10.1038/ng.1054

N/A

0.921DataRank · unranked

464 citations

Philippe Rocca-Serra, Dawn Field, Eamonn Maguire, Chris Taylor, Jessica I. Hoell +48 more

Quantitative prediction of variant effects on alternative splicing in MAPT using endogenous pre-messenger RNA structure probing

eLife(2022)10.7554/elife.73888

N/A

0.691DataRank · unranked

24 citations

Lela Lackey, Justin M. Waldern, Abhishek Dey, Anthony M. Mustoe, Kevin M. Weeks +3 more

Multiple conformations are a conserved and regulatory feature of the RB1 5' UTR

UNC Libraries(2020)10.17615/en3x-z731

N/A

0DataRank · unranked

7 citations

Matthew Halvorsen, Alain Laederach, Amanda Solem, Katrina M. Kutchko, Nathaniel J. Moorman +4 more

Transcending the prediction paradigm: novel applications of SHAPE to RNA function and evolution

UNC Libraries(2020)10.17615/yce5-nm66

N/A

0DataRank · unranked

5 citations

Katrina M. Kutchko, Alain Laederach

Characterization of a COPD-Associated NPNT Functional Splicing Genetic Variant in Human Lung Tissue via Long-Read Sequencing

medRxiv(2020)10.1101/2020.10.20.20203927

N/A

0DataRank · unranked

13 citations

Zhonghui Xu, Gloria Sheynkman, Craig P. Hersh, Michael H. Cho, Edwin K. Silverman +4 more

Mapping the Kinetic Barriers of a Large RNA Molecule's Folding Landscape

UNC Libraries(2020)10.17615/k6dh-3a62

N/A

0DataRank · unranked

0 citations

Jörg C. Schlatterer, Michael Brenowitz, Joshua S. Martin, Alain Laederach

Understanding the Role of Three-Dimensional Topology in Determining the Folding Intermediates of Group I Introns

UNC Libraries(2020)10.17615/k1ek-7j56

N/A

0DataRank · unranked

0 citations

Michael Brenowitz, Alain Laederach, Magdalena Jonikas, Chunxia Chen, Joshua S. Martin +1 more

Increased Transcript Complexity in Genes Associated with Chronic Obstructive Pulmonary Disease

UNC Libraries(2020)10.17615/8c8p-b592

N/A

0DataRank · unranked

0 citations

Evonne McArthur, Alain Laederach, Lela Lackey

Structure-Function Model for Kissing Loop Interactions That Initiate Dimerization of Ty1 RNA

UNC Libraries(2020)10.17615/fb5q-hd04

N/A

0DataRank · unranked

0 citations

Justin Ritz, Eric Gamache, Alain Laederach, Jung H. Doh, Stanislav Bellaousov +2 more

RNA molecules with conserved catalytic cores but variable peripheries fold along unique energetically optimized pathways

UNC Libraries(2020)10.17615/c2bs-nn31

N/A

0DataRank · unranked

0 citations

M. Brenowitz, Souraja Mitra, R. B. Altman, B. L. Golden, Alain Laederach

An RNA structure-mediated, posttranscriptional model of human α-1-antitrypsin expression

UNC Libraries(2020)10.17615/j29f-he44

N/A

0DataRank · unranked

0 citations

Heather A. Vincent, Lela Lackey, Nathaniel J. Moorman, Silvia B. V. Ramos, Amanda Solem +6 more

Primary and Secondary Sequence Structure Requirements for Recognition and Discrimination of Target RNAs by Pseudomonas aeruginosa RsmA and RsmF

UNC Libraries(2020)10.17615/z5s3-qp45

N/A

0DataRank · unranked

0 citations

Manisha R. Diaz, Alain Laederach, Wes Sanders, Matthew C. Wolfgang, Thomas Bair +3 more

A novel application of pattern recognition for accurate SNP and indel discovery from high-throughput data: Targeted resequencing of the glucocorticoid receptor co-chaperone FKBP5 in a Caucasian population

UNC Libraries(2020)10.17615/2awd-kn68

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0DataRank · unranked

0 citations

Alain Laederach, Irene Moon, Sandro Rossetti, Julie A. Johnson, Bruce W. Eckloff +3 more

Single Molecule Cluster Analysis dissects splicing pathway conformational dynamics

UNC Libraries(2020)10.17615/9186-ab56

N/A

0DataRank · unranked

0 citations

Mario R. Blanco, Joshua S. Martin, John Abelson, Nils G. Walter, Ramya Krishnan +2 more

Detecting riboSNitches with RNA folding algorithms: a genome-wide benchmark

UNC Libraries(2020)10.17615/eh6k-d336

N/A

0DataRank · unranked

0 citations

Meredith Corley, Howard Y. Chang, Alain Laederach, Amanda Solem, Kun Qu

Classification of RNA structure change by “gazing” at experimental data

UNC Libraries(2020)10.17615/984a-h270

N/A

0DataRank · unranked

0 citations

Alain Laederach, Chanin Tolson Woods

Direct Mapping of Higher-Order RNA Interactions by SHAPE-JuMP

Biochemistry(2021)10.1021/acs.biochem.1c00270

N/A

0DataRank · unranked

37 citations

Catherine A. Giannetti, Gillian Houlihan, Matthew J. Smola, Greggory M. Rice, Jian Wang +5 more

Disease-associated human genetic variation through the lens of precursor and mature RNA structure

Human Genetics(2021)10.1007/s00439-021-02395-9

N/A

0DataRank · unranked

19 citations

Jayashree Kumar, Alain Laederach, Justin M. Waldern

In vivo architecture of the telomerase RNA catalytic core in Trypanosoma brucei

Nucleic Acids Research(2021)10.1093/nar/gkab1042

N/A

0DataRank · unranked

13 citations

Anaïs Monroy‐Eklund, Kaitlin Klotz, Arpita Saha, Justin A. Davis, Bibo Li +3 more

Alternative poly-adenylation modulates α1-antitrypsin expression in chronic obstructive pulmonary disease

PLoS Genetics(2021)10.1371/journal.pgen.1009912

N/A

0DataRank · unranked

11 citations

Aaztli Coria, Auyon Ghosh, Phil Grayeski, Abigail Hatfield, Vijay Shankar +11 more

A novel algorithm for ranking RNA structure candidates

Biophysical Journal(2021)10.1016/j.bpj.2021.12.004

N/A

0DataRank · unranked

7 citations

Alain Laederach, Anastacia Wienecke

Identifying proximal RNA interactions from cDNA-encoded crosslinks with ShapeJumper

PLoS Computational Biology(2021)10.1371/journal.pcbi.1009632

N/A

0DataRank · unranked

6 citations

Catherine A. Giannetti, Alain Laederach, Kevin M. Weeks, Thomas W. Christy

Multiple conformations are a conserved and regulatory feature of the RB1 5′ UTR

UNC Libraries(2021)10.17615/1aym-xw92

N/A

0DataRank · unranked

3 citations

Amanda Solem, Matthew Halvorsen, Gabriela Phillips, Ben Ziehr, Nathaniel J. Moorman +5 more

To knot or not to knot: Multiple conformations of the SARS-CoV-2 frameshifting RNA element

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.31.437955

N/A

0DataRank · unranked

3 citations

Qiyao Zhu, Abhishek Dey, Swati Jain, Shuting Yan, Alain Laederach +1 more

Identifying proximal RNA interactions from cDNA-encoded crosslinks with ShapeJumper

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.10.447916

N/A

0DataRank · unranked

2 citations

Catherine A. Giannetti, Alain Laederach, Kevin M. Weeks, Thomas W. Christy

Quantitative prediction of variant effects on alternative splicing using endogenous pre-messenger RNA structure probing

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.13.460117

N/A

0DataRank · unranked

1 citations

Lela Lackey, Justin M. Waldern, Abhishek Dey, David H. Mathews, Alain Laederach +1 more

Cigarette Smoking-Associated Isoform Switching and 3’ UTR Lengthening Via Alternative Polyadenylation

medRxiv(2021)10.1101/2021.06.09.21258495

N/A

0DataRank · unranked

0 citations

John Platig, Sool Lee, Adel Boueiz, Rob Chase, Dhawal Jain +9 more

Distinct responses to rare codons in select Drosophila tissues

eLife(2022)10.7554/elife.76893

N/A

0DataRank · unranked

30 citations

Rebeccah K Stewart, Michael Rogers, Ivan Jimenez Ruiz, Erez Cohen, Alain Laederach +4 more

Global 5′-UTR RNA structure regulates translation of a SERPINA1 mRNA

Nucleic Acids Research(2022)10.1093/nar/gkac739

N/A

0DataRank · unranked

26 citations

Chase A. Weidmann, Jayashree Kumar, Lela Lackey, Anthony M. Mustoe, Steven Busan +3 more

Sequence and tissue targeting specificity of ZFP36L2 reveals Elavl2 as a novel target with co-regulation potential

Nucleic Acids Research(2022)10.1093/nar/gkac209

N/A

0DataRank · unranked

10 citations

Matthew Ardizzone, Hilal Hekimoğlu, Breanne M. Hatfield, Justin M. Waldern, Abhishek Dey +4 more

Rotavirus RNA chaperone mediates global transcriptome-wide increase in RNA backbone flexibility

Nucleic Acids Research(2022)10.1093/nar/gkac738

N/A

0DataRank · unranked

9 citations

Anastacia Wienecke, Michael L. Knight, Daniel Desirò, Alain Laederach, Alexander Borodavka +1 more

Rotavirus RNA chaperone mediates global transcriptome-wide increase in RNA backbone flexibility

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.04.474988

N/A

0DataRank · unranked

2 citations

Anastacia Wienecke, Alexander Borodavka, Alain Laederach, Aaztli Coria

Structural conservation of MALAT1 long non-coding RNA in cells and in evolution

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.29.502018

N/A

0DataRank · unranked

1 citations

Colin D. Taylor, Chase A. Weidmann, Christina L. Burch, Alain Laederach, Anaïs Monroy‐Eklund

Quantitative prediction of variant effects on alternative splicing in MAPT using endogenous pre-messenger RNA structure probing

UNC Libraries(2022)10.17615/n0h1-jc89

N/A

0DataRank · unranked

0 citations

Abhishek Dey, Alain Laederach, Anthony M. Mustoe, Lela Lackey, Kevin M. Weeks +3 more

Structural analysis of MALAT1 long noncoding RNA in cells and in evolution

RNA(2023)10.1261/rna.079388.122

N/A

0DataRank · unranked

23 citations

Colin D. Taylor, Chase A. Weidmann, Christina L. Burch, Alain Laederach, Anaïs Monroy‐Eklund

Coordinated expression of replication-dependent histone genes from multiple loci promotes histone homeostasis in Drosophila

Molecular Biology of the Cell(2023)10.1091/mbc.e22-11-0532

N/A

0DataRank · unranked

10 citations

Justin M. Waldern, Colin D. Taylor, Alain Laederach, William F. Marzluff, Robert J. Duronio +1 more

Orb2 enables rare-codon-enriched mRNA expression during Drosophila neuron differentiation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.26.550700

N/A

0DataRank · unranked

0 citations

Patrick Viet-Quoc Nguyen, Alain Laederach, Pelin Volkan, Jessica K. Sawyer, Donald T. Fox +1 more

Abolished frameshifting for predicted structure-stabilizing SARS-CoV-2 mutants: implications to alternative conformations and their statistical structural analyses

RNA(2024)10.1261/rna.080035.124

N/A

0DataRank · unranked

21 citations

Shuting Yan, Tamar Schlick, Alain Laederach, Abhishek Dey

Orb2 enables rare-codon-enriched mRNA expression during Drosophila neuron differentiation

Nature Communications(2024)10.1038/s41467-024-48344-8

N/A

0DataRank · unranked

10 citations

P Nguyen, Alain Laederach, Pelin Volkan, Jessica K. Sawyer, Donald T. Fox +1 more

Visualizing RNA structure ensembles by single-molecule correlated chemical probing

Current Opinion in Structural Biology(2024)10.1016/j.sbi.2024.102877

N/A

0DataRank · unranked

8 citations

Alain Laederach, Kevin M. Weeks, J. Winston Arney

Colocalization analysis of 3′ UTR alternative polyadenylation quantitative trait loci reveals novel mechanisms underlying associations with lung function

Human Molecular Genetics(2024)10.1093/hmg/ddae055

N/A

0DataRank · unranked

4 citations

Wonji Kim, Zhonghui Xu, Robert Chase, Michael H. Cho, Alain Laederach +3 more

Abolished frameshifting for predicted structure-stabilizing SARS-CoV-2 mutants: Implications to alternative conformations and their statistical structural analyses

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.28.586935

N/A

0DataRank · unranked

2 citations

Shuting Yan, Tamar Schlick, Alain Laederach, Abhishek Dey

Using SHAPE-MaP To Model RNA Secondary Structure and Identify 3'UTR Variation in Chikungunya Virus.

UNC Libraries(2024)10.17615/mxrz-yq05

N/A

0DataRank · unranked

0 citations

N.J. Moorman, Mark T. Heise, Sharon Taft-Benz, Emily A. Madden, Grace L. Reynolds +10 more

Abolished frameshifting for predicted structure-stabilizing SARS-CoV-2 mutants: Implications to alternative conformations and their statistical structural analyses

UNC Libraries(2024)10.17615/qmxg-9w36

N/A

0DataRank · unranked

0 citations

Alain Laederach, Abhishek Dey, Tamar Schlick, Shuting Yan

Orb2 enables rare-codon-enriched mRNA expression during Drosophila neuron differentiation

UNC Libraries(2024)10.17615/tf24-fv57

N/A

0DataRank · unranked

0 citations

Alain Laederach, Pelin Volkan, Rebeccah K. Stewart, Donald T. Fox, P Nguyen +1 more

Characterisation of a COPD-associated nephronectin (NPNT) functional splicing genetic variant in human lung tissuevialong-read sequencing

European Respiratory Journal(2025)10.1183/13993003.01407-2024

N/A

0DataRank · unranked

6 citations

Anastacia Wienecke, Zhonghui Xu, Tao Liu, Gloria Sheynkman, Craig P. Hersh +11 more

RNA Structural Ensemble Determinants of −1 Programmed Ribosomal Frameshifting Efficiency Across Coronavirus Evolution

Journal of Molecular Biology(2025)10.1016/j.jmb.2025.169512

N/A

0DataRank · unranked

2 citations

Tamar Schlick, Alain Laederach, Scott R. Allen

Structural determinants of inverted Alu-mediated backsplicing revealed by -MaP and -JuMP

Nucleic Acids Research(2025)10.1093/nar/gkaf433

N/A

0DataRank · unranked

2 citations

Colin D. Taylor, Catherine A. Giannetti, Patrick S. Irving, Scott R. Allen, Mingyi Zhu +5 more

Visualizing RNA structure ensembles by single-molecule correlated chemical probing

UNC Libraries(2025)10.17615/cd6w-7872

N/A

0DataRank · unranked

0 citations

J. Winston Arney, Kevin M. Weeks, Alain Laederach

Using SHAPE-MaP To Model RNA Secondary Structure and Identify 3′UTR Variation in Chikungunya Virus

Journal of Virology(2020)10.1128/jvi.00701-20

N/A

0DataRank · unranked

47 citations

Kenneth S. Plante, Clayton R. Morrison, Katrina M. Kutchko, Wes Sanders, Kristin M. Long +10 more