Yu Chen

Also affiliated with Nanjing Forestry University, University of South Florida, Zhejiang Ocean University, Institute of Botany

Biochemistry, Genetics and Molecular BiologyMedicineComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 25 papers. Top paper: “Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease”.

Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease

Cell Research(2020)10.1038/s41422-020-0356-z

N/A

1.0DataRank · unranked

880 citations

M. Sacco, Brett L. Hurst, Julia A. Townsend, Yanmei Hu, Tommy Szeto +6 more

Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against M pro and cathepsin L

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.27.223727

N/A

0.866DataRank · unranked

18 citations

Chunlong Ma, Panagiotis Lagarias, Ang Gao, Julia A. Townsend, Xiangzhi Meng +12 more

Discovery of SARS-CoV-2 papain-like protease inhibitors through a combination of high-throughput screening and FlipGFP-based reporter assay

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.15.435551

N/A

0.408DataRank · unranked

8 citations

M. Sacco, Chunlong Ma, Julia A. Townsend, Naoya Kitamura, Yanmei Hu +10 more

Metallocenyl 7‐ACA Conjugates: Antibacterial Activity Studies and Atomic‐Resolution X‐ray Crystal Structure with CTX‐M β‐Lactamase

ChemBioChem(2020)10.1002/cbic.202000054

N/A

0DataRank · unranked

11 citations

Łukasz Szczupak, Aleksandra Kowalczyk, Gracia Mendoza, Manuel Arruebo, Lian Jacobs +4 more

Boceprevir, GC-376, and calpain inhibitors II, XII inhibit SARS-CoV-2 viral replication by targeting the viral main protease

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.20.051581

N/A

0DataRank · unranked

92 citations

M. Sacco, Brett L. Hurst, Julia A. Townsend, Yanmei Hu, Tommy Szeto +6 more

An expedited approach towards the rationale design of non-covalent SARS-CoV-2 main protease inhibitors with in vitro antiviral activity

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.19.423537

N/A

0DataRank · unranked

2 citations

M. Sacco, Chunlong Ma, Yanmei Hu, Julia A. Townsend, Xiangzhi Meng +10 more

Suppressors of YpsA-mediated cell division inhibition in Bacillus subtilis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.12.946632

N/A

0DataRank · unranked

1 citations

Brooke R. Tomlinson, M. Sacco, Judy J. Chen, Anika N. Ali, Yu Chen +3 more

GpsB coordinates cell division and cell surface decoration by wall teichoic acids in Staphylococcus aureus

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.29.462461

N/A

0DataRank · unranked

2 citations

Sebastian J. Khan, M. Sacco, Catherine M. Spanoudis, Abigail Hough, Yu Chen +2 more

The P132H mutation in the main protease of Omicron SARS-CoV-2 decreases thermal stability without compromising catalysis or small-molecule drug inhibition

Cell Research(2022)10.1038/s41422-022-00640-y

N/A

0DataRank · unranked

148 citations

Yanmei Hu, Maura V. Gongora, Flora Meilleur, M. Trent Kemp, Xiujun Zhang +3 more

A unique class of Zn2+-binding serine-based PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile

Nature Communications(2022)10.1038/s41467-022-32086-6

N/A

0DataRank · unranked

28 citations

Shaohui Wang, Swamy R. Adapa, Xiujun Zhang, Eric M. Lewandowski, Maura V. Gongora +14 more

Structural Insights into Molecular Recognition by Human Chemokine CCL19

Biochemistry(2022)10.1021/acs.biochem.1c00759

N/A

0DataRank · unranked

5 citations

Kyle G. Kroeck, Lian Jacobs, Tyler G. Fenske, Robin N. Witt, Alyssa M. Hintz +7 more

Naturally occurring mutations of SARS-CoV-2 main protease confer drug resistance to nirmatrelvir

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.28.497978

N/A

0DataRank · unranked

93 citations

Eric M. Lewandowski, Haozhou Tan, Xiaoming Zhang, Ryan T. Morgan, Xiujun Zhang +8 more

The P132H mutation in the main protease of Omicron SARS-CoV-2 decreases thermal stability without compromising catalysis or small-molecule drug inhibition

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.26.477774

N/A

0DataRank · unranked

10 citations

Yanmei Hu, Maura V. Gongora, Flora Meilleur, M. Trent Kemp, Xiujun Zhang +3 more

A yeast-based system to study SARS-CoV-2 Mpro structure and to identify nirmatrelvir resistant mutations

Research Square(2022)10.21203/rs.3.rs-1942964/v1

N/A

0DataRank · unranked

7 citations

Eric M. Lewandowski, Yanmei Hu, Austin A. Lipinski, Ryan T. Morgan, Lian Jacobs +8 more

Staphylococcus aureus FtsZ and PBP4 bind to the conformationally dynamic N-terminal domain of GpsB

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.25.513704

N/A

0DataRank · unranked

7 citations

Lauren R. Hammond, Radwan Ebna Noor, Dipanwita Bhattacharya, Jesper J. Madsen, Xiujun Zhang +8 more

Naturally Occurring Mutations of SARS-CoV-2 Main Protease Confer Drug Resistance to Nirmatrelvir

ACS Central Science(2023)10.1021/acscentsci.3c00538

N/A

0DataRank · unranked

309 citations

Eric M. Lewandowski, Haozhou Tan, Xiaoming Zhang, Ryan T. Morgan, Xiujun Zhang +8 more

A yeast-based system to study SARS-CoV-2 Mpro structure and to identify nirmatrelvir resistant mutations

PLoS Pathogens(2023)10.1371/journal.ppat.1011592

N/A

0DataRank · unranked

29 citations

Eric M. Lewandowski, Yanmei Hu, Austin A. Lipinski, A.A. Aljasser, Mariliz Colon-Ascanio +10 more

Exploring diverse reactive warheads for the design of SARS-CoV-2 main protease inhibitors

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115667

N/A

0DataRank · unranked

27 citations

M. Sacco, Haozhou Tan, Kan Li, Ryan Joyce, Xiujun Zhang +3 more

Inhibition of Hypoxia-Inducible Transcription Factor (HIF-1α) Signaling with Sulfonyl-γ-AApeptide Helices

Journal of the American Chemical Society(2023)10.1021/jacs.3c06694

N/A

0DataRank · unranked

19 citations

Sami Abdulkadir, Xue Zhao, Peng Sang, Αναστασία Τοματσίδου, Xiujun Zhang +7 more

Development of the Safe and Broad‐Spectrum Aldehyde and Ketoamide Mpro inhibitors Derived from the Constrained α, γ‐AA Peptide Scaffold

Chemistry - A European Journal(2023)10.1002/chem.202300476

N/A

0DataRank · unranked

4 citations

Chunlong Ma, M. Sacco, Songyi Xue, Mentalla Mahmoud, Laurent Calcul +4 more

Staphylococcus aureus FtsZ and PBP4 bind to the conformationally dynamic N-terminal domain of GpsB

eLife(2024)10.7554/elife.85579

N/A

0DataRank · unranked

18 citations

Lauren R. Hammond, Radwan Ebna Noor, Dipanwita Bhattacharya, Lily J McKnight, Jesper J. Madsen +9 more

Distal Protein-Protein Interactions Contribute to SARS-CoV-2 Main Protease Substrate Binding and Nirmatrelvir Resistance

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.01.587566

N/A

0DataRank · unranked

2 citations

Xiujun Zhang, Haozhou Tan, Aiden C Jaskolka-Brown, Navita Kohaal, Aliaksandra Frazier +5 more

Distal protein-protein interactions contribute to nirmatrelvir resistance

Nature Communications(2025)10.1038/s41467-025-56651-x

N/A

0DataRank · unranked

11 citations

Xiujun Zhang, Haozhou Tan, Aiden C Jaskolka-Brown, Navita Kohaal, Aliaksandra Frazier +5 more

Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M pro and cathepsin L

Science Advances(2020)10.1126/sciadv.abe0751

N/A

0DataRank · unranked

399 citations

Chunlong Ma, Panagiotis Lagarias, Ang Gao, Julia A. Townsend, Xiangzhi Meng +12 more

KPC-2 β-lactamase enables carbapenem antibiotic resistance through fast deacylation of the covalent intermediate

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.015050

N/A

0DataRank · unranked

40 citations

I. Furey, O.A. Pemberton, David M. Boragine, Yu Chen, Timothy Palzkill +1 more