Jennifer A. Roth

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 39 papers. Top paper: “Discovering the anticancer potential of non-oncology drugs by systematic viability profiling”.

Discovering the anticancer potential of non-oncology drugs by systematic viability profiling

Nature Cancer(2020)10.1038/s43018-019-0018-6

N/A

5.5DataRank · unranked

892 citations

Rohith T. Nagari, Ryan D. Spangler, Jordan Rossen, Mustafa Kocak, Jordan Bryan +33 more

Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action

Nature Communications(2020)10.1038/s41467-020-17440-w

N/A

5.2DataRank · unranked

186 citations

Brenton R. Paolella, Allison C. Warren, Kathryn Geiger-Schuller, Tsukasa Shibue, Michael Rothberg +18 more

Noncanonical open reading frames encode functional proteins essential for cancer cell survival

Nature Biotechnology(2021)10.1038/s41587-020-00806-2

N/A

4.5DataRank · unranked

198 citations

Oana M. Enache, Victor Luria, Karsten Krug, Karl R. Clauser, Joshua M. Dempster +21 more

Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy

Nature(2024)10.1038/s41586-024-07205-6

N/A

4.2DataRank · unranked

326 citations

Bianca J. Lee, Jingjing Jiang, Aidan C.A. Tomlinson, Kyle J. Seamon, Alessia Mira +48 more

Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer

Nature(2024)10.1038/s41586-024-07379-z

N/A

3.9DataRank · unranked

182 citations

Jingjing Jiang, Tanner C. Dalton, Álvaro Curiel‐García, A. Cole Edwards, Yingyun Wang +61 more

Genome-scale screens identify factors regulating tumor cell responses to natural killer cells

Nature Genetics(2021)10.1038/s41588-021-00889-w

N/A

2.5DataRank · unranked

98 citations

Emily Lowry, Nicky A. Beelen, Minasri Borah, Suha Naffar-Abu Amara, Chris Mader +26 more

Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma

Molecular Cell(2024)10.1016/j.molcel.2023.12.003

N/A

1.5DataRank · unranked

69 citations

Jorge Ruiz-Orera, Ian Yannuzzi, Rakesh Murugesan, Adam Brown, Karl R. Clauser +19 more

Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity

Nature Genetics(2020)10.1038/s41588-020-00726-6

N/A

0.918DataRank · unranked

455 citations

Rotem Tal, Zhanna Orlova, Michael S. Cuoco, James M. McFarland, Allison C. Warren +22 more

Non-canonical open reading frames encode functional proteins essential for cancer cell survival

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.10.981001

N/A

0.686DataRank · unranked

12 citations

Oana M. Enache, Victor Luria, Karsten Krug, Karl R. Clauser, Joshua M. Dempster +21 more

Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.04.539399

N/A

0.504DataRank · unranked

8 citations

Jorge Ruiz-Orera, Ian Yannuzzi, Rakesh Murugesan, Adam Brown, Karl R. Clauser +19 more

Pan-cancer single cell RNA-seq uncovers recurring programs of cellular heterogeneity

bioRxiv (Cold Spring Harbor Laboratory)(2019)10.1101/807552

N/A

0.425DataRank · unranked

16 citations

Rotem Tal, Zhanna Orlova, Michael S. Cuoco, James M. McFarland, Allison C. Warren +21 more

Multiplexed single-cell profiling of post-perturbation transcriptional responses to define cancer vulnerabilities and therapeutic mechanism of action

bioRxiv (Cold Spring Harbor Laboratory)(2019)10.1101/868752

N/A

0.353DataRank · unranked

5 citations

Brenton R. Paolella, Allison C. Warren, Kathryn Geiger-Schuller, Tsukasa Shibue, Michael Rothberg +18 more

Screening in serum-derived medium reveals differential response to compounds targeting metabolism

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.25.529972

N/A

0DataRank · unranked

8 citations

Ahmed Ali, Dominick Casalena, Brian T. Do, Raphaël Ferreira, Jaime H. Cheah +25 more

Mechanism of Action of KL-50, a Novel Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers

ChemRxiv(2023)10.26434/chemrxiv-2023-zwj94

N/A

0DataRank · unranked

1 citations

Anna Lo, Olga Fedorova, James L. Elia, Susan Gueble, Kingson Lin +15 more

Mechanisms of Resistance to Oncogenic KRAS Inhibition in Pancreatic Cancer

Cancer Discovery(2024)10.1158/2159-8290.cd-24-0177

N/A

0DataRank · unranked

243 citations

Megan T. Hoffman, Laleh Abbassi, Ziyue Li, Francesca Paradiso, Brendan D. Parent +50 more

Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition

Nature Communications(2024)10.1038/s41467-024-47102-0

N/A

0DataRank · unranked

15 citations

Melissa J. Bikowitz, Logan H. Sigua, Yang Zhang, Audrey Mercier, Yousef Khashana +19 more

A Benzarone Derivative Inhibits EYA to Suppress Tumor Growth in SHH Medulloblastoma

Cancer Research(2024)10.1158/0008-5472.can-22-3784

N/A

0DataRank · unranked

11 citations

Maria F. Pazyra‐Murphy, Hyuk‐Soo Seo, Sirano Dhe‐Paganon, Sylwia A. Stopka, Marina DiPiazza +12 more

Mechanism of Action of KL-50, a Candidate Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers

Journal of the American Chemical Society(2024)10.1021/jacs.3c06483

N/A

0DataRank · unranked

7 citations

Anna Lo, Olga Fedorova, James L. Elia, Susan E. Gueble, Kingson Lin +13 more

Highly specific intracellular ubiquitination of a small molecule

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.26.577493

N/A

0DataRank · unranked

4 citations

Enrique Garcia-Rivera, Dylan C. Mitchell, Joel M. Chick, Micah Maetani, John M. Knapp +13 more

Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy

UNC Libraries(2024)10.17615/1fr6-tv06

N/A

0DataRank · unranked

0 citations

Nicole Nasholm, Chiara Ambrogio, Anthony N. Milin, Yang Liu, Elsa Quintana +48 more

Targeting histone H2B acetylated enhanceosomes via p300/CBP degradation in prostate cancer

Nature Genetics(2025)10.1038/s41588-025-02336-6

N/A

0DataRank · unranked

19 citations

Zhixiang Chen, Yuanyuan Qiao, Jean C. Tien, Eleanor Young, Rahul Mannan +24 more

An allele-agnostic mutant-KRAS inhibitor suppresses tumor maintenance signals and reprograms tumor immunity in pancreatic cancer

Science Translational Medicine(2025)10.1126/scitranslmed.adt5511

N/A

0DataRank · unranked

10 citations

Francesca Paradiso, Clint A. Stalnecker, Benson Chellakkan Selvanesan, Fredrik I. Thege, David H. Peng +40 more

Tegavivint triggers TECR-dependent nonapoptotic cancer cell death

Nature Chemical Biology(2025)10.1038/s41589-025-01913-4

N/A

0DataRank · unranked

6 citations

Ziwei Wang, Alby J. Joseph, Brianna Johnson, Alyssa A. Chan, Cassandra M. Decosto +21 more

Defining the Antitumor Mechanism of Action of a Clinical-stage Compound as a Selective Degrader of the Nuclear Pore Complex

Cancer Discovery(2025)10.1158/2159-8290.cd-25-0271

N/A

0DataRank · unranked

5 citations

Wenzhi Ji, Brendan G. Dwyer, Joey Lu, Jing Bian, Gianna M. Colombo +23 more

CF10 Displayed Improved Activity Relative to 5-FU in a Mouse CRLM Model Under Conditions of Physiological Folate

Cancers(2025)10.3390/cancers17172739

N/A

0DataRank · unranked

2 citations

Xue Ma, Wencheng Li, Ralph B. D’Agostino, Matthew G. Rees, Melissa M. Ronan +3 more

Generative Design of Cell Type-Specific RNA Splicing Elements for Programmable Gene Regulation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.05.686847

N/A

0DataRank · unranked

2 citations

Manson Jim, Mounica Vallurupalli, Kai Cao, A. Torres, Jong S. Leong +13 more

Overcoming rapaprotin resistance through inhibition of P-glycoprotein

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.28.679086

N/A

0DataRank · unranked

0 citations

Thomas Asbell, A. V. Subba Rao, Kalyan Kumar Pasunooti, Jian Zhang, Matthew G. Rees +3 more

Synthesis and Biological Evaluation of Colibactin Derivatives

ACS Chemical Biology(2025)10.1021/acschembio.5c00639

N/A

0DataRank · unranked

0 citations

Olga Fedorova, Collin D. Heer, Matthew G. Rees, Melissa M. Ronan, Jennifer A. Roth +3 more

INK4 Tumor Suppressor Proteins Mediate Resistance to CDK4/6 Kinase Inhibitors

Cancer Discovery(2021)10.1158/2159-8290.cd-20-1726

N/A

0DataRank · unranked

166 citations

Baishan Jiang, Jiaye Guo, Hong Shao, Isabella Del Priore, Qing Chang +20 more

Methionine synthase is essential for cancer cell proliferation in physiological folate environments

Nature Metabolism(2021)10.1038/s42255-021-00486-5

N/A

0DataRank · unranked

106 citations

Alicia M. Darnell, Montana F. Reilly, Tenzin Kunchok, Lena Joesch-Cohen, Daniel W. Rosenberg +6 more

Massively parallel pooled screening reveals genomic determinants of nanoparticle-cell interactions

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.05.438521

N/A

0DataRank · unranked

4 citations

Joelle P. Straehla, Hannah C. Safford, Mustafa Kocak, Matthew G. Rees, Melissa M. Ronan +12 more

Salvage of Ribose from Uridine or RNA Supports Glycolysis when Glucose is Limiting

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.10.447789

N/A

0DataRank · unranked

4 citations

Owen S. Skinner, Akinori Kawakami, Russel P. Goodman, Hongying Shen, Lajos V. Kemény +6 more

Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery

Science(2022)10.1126/science.abm5551

N/A

0DataRank · unranked

197 citations

Joelle P. Straehla, Hannah C. Safford, Mustafa Kocak, Matthew G. Rees, Melissa M. Ronan +12 more

Single-cell functional genomics of natural killer cell evasion in blood cancers

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.22.504722

N/A

0DataRank · unranked

3 citations

Sara Gandolfi, Jani Huuhtanen, Olga Dashevsky, Khalid Saeed, Jay Klievink +26 more

Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions

Nature Metabolism(2023)10.1038/s42255-023-00774-2

N/A

0DataRank · unranked

109 citations

Joan Blanco-Fernández, Russell P. Goodman, Akinori Kawakami, Hongying Shen, Lajos V. Kemény +7 more

Structure-Based Design of Y-Shaped Covalent TEAD Inhibitors

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.2c01548

N/A

0DataRank · unranked

47 citations

Mengyang Fan, Wenzhi Ji, Jason Tse, Inchul You, Scott B. Ficarro +16 more

Screening in serum-derived medium reveals differential response to compounds targeting metabolism

Cell chemical biology(2023)10.1016/j.chembiol.2023.08.007

N/A

0DataRank · unranked

31 citations

Ahmed Ali, Dominick Casalena, Brian T. Do, Raphaël Ferreira, Jaime H. Cheah +29 more

Oncogenic Cells of Renal Embryonic Lineage Sensitive to the Small-Molecule Inhibitor QC6352 Display Depletion of KDM4 Levels and Disruption of Ribosome Biogenesis

Molecular Cancer Therapeutics(2023)10.1158/1535-7163.mct-23-0312

N/A

0DataRank · unranked

5 citations

Carolyn M. Jablonowski, Jie Fang, Andrew M. Fleming, Hyea Jin Gil, Andrew S. Boghossian +9 more

Tumor-selective effects of active RAS inhibition in pancreatic ductal adenocarcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.03.569791

N/A

0DataRank · unranked

11 citations

Jingjing Jiang, Alvaro Curiel-Garcia, Yingyun Wang, Bianca J. Lee, Margo Orlen +42 more