🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

David Stein

Brigham and Women's Hospital

ORCID: 0000-0002-5131-8313

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 15 papers. Top paper: “Identification of discriminative gene-level and protein-level features associated with pathogenic gain-of-function and loss-of-function variants”.

Identification of discriminative gene-level and protein-level features associated with pathogenic gain-of-function and loss-of-function variants

The American Journal of Human Genetics(2021)10.1016/j.ajhg.2021.10.007

N/A

0.612DataRank · unranked

58 citations

David Stein, Aayushee Jain, Kumardeep Chaudhary, Girish N. Nadkarni, Tielman Van Vleck +8 more

Structural analysis of genomic and proteomic signatures reveal dynamic expression of intrinsically disordered regions in breast cancer

iScience(2024)10.1016/j.isci.2024.110640

N/A

0.104DataRank · unranked

1 citations

Yifei Sun, Christian Dallago, Timothy Karl, David Stein, Burkhard Rost +6 more

Hybridization Chain Reaction Fluorescence In Situ Hybridization (HCR-FISH) in Ambystoma mexicanum Tissue

Methods in molecular biology(2022)10.1007/978-1-0716-2659-7_6

N/A

0DataRank · unranked

27 citations

Timothy J. Duerr, David Stein, Evan T. Mun, James R. Monaghan, Alex M. Lovely

Dynamics of the most common pathogenic mtDNA variant m.3243A > G demonstrate frequency-dependency in blood and positive selection in the germline

Human Molecular Genetics(2022)10.1093/hmg/ddac149

N/A

0DataRank · unranked

14 citations

Sarah J. Pickett, Zoë Fleischmann, Mark Khrapko, Auden Cote‐L’Heureux, Dylan Aidlen +9 more

Structural signatures: a web server for exploring a database of and generating protein structural features from human cell lines and tissues

Database(2022)10.1093/database/baac053

N/A

0DataRank · unranked

3 citations

David Stein, Rayees Rahman, Ravi Iyengar, Avner Schlessinger, Nicole Zatorski

Genome-wide prediction of pathogenic gain- and loss-of-function variants from ensemble learning of a diverse feature set

Genome Medicine(2023)10.1186/s13073-023-01261-9

N/A

0DataRank · unranked

49 citations

Meltem Ece Kars, Yiming Wu, Çiğdem Sevim Bayrak, Peter D. Stenson, D.N. Cooper +3 more

Structural Analysis of Genomic and Proteomic Signatures Reveal Dynamic Expression of Intrinsically Disordered Regions in Breast Cancer and Tissue

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.23.529755

N/A

0DataRank · unranked

1 citations

Yifei Sun, Abdülkadir Elmas, Christian Dallago, Timothy Karl, David Stein +5 more

Development of a human genetics-guided priority score for 19,365 genes and 399 drug indications

Nature Genetics(2024)10.1038/s41588-023-01609-2

N/A

0DataRank · unranked

32 citations

Ben Omega Petrazzini, David Stein, Joshua K. Park, Iain S. Forrest, Kyle Gibson +12 more

A comprehensive exploration of the druggable conformational space of protein kinases using AI-predicted structures

PLoS Computational Biology(2024)10.1371/journal.pcbi.1012302

N/A

0DataRank · unranked

18 citations

Yan Chak Li, David Stein, Gaurav Pandey, Avner Schlessinger, Noah B. Herrington

Expanding drug targets for 112 chronic diseases using a machine learning-assisted genetic priority score

Nature Communications(2024)10.1038/s41467-024-53333-y

N/A

0DataRank · unranked

11 citations

Áine Duffy, Ben Omega Petrazzini, Ha My T. Vy, David Stein, Matthew Mort +8 more

Deciphering the digenic architecture of congenital heart disease using trio exome sequencing data

The American Journal of Human Genetics(2025)10.1016/j.ajhg.2025.01.024

N/A

0DataRank · unranked

8 citations

David Stein, Peter D. Stenson, D.N. Cooper, Wendy K. Chung, Peter J. Gruber +6 more

Expanding the utility of variant effect predictions with phenotype-specific models

Nature Communications(2025)10.1038/s41467-025-66607-w

N/A

0DataRank · unranked

3 citations

Meltem Ece Kars, Baptiste Milisavljevic, Matthew Mort, Peter D. Stenson, Jean-Laurent Casanova +6 more

Genetic evidence informs the direction of therapeutic modulation in drug development

npj Drug Discovery.(2025)10.1038/s44386-025-00027-0

N/A

0DataRank · unranked

2 citations

Áine Duffy, Joshua K. Park, David Stein, Avner Schlessinger, Yuval Itan +6 more

Development of a genetic priority score to predict drug side effects using human genetic evidence

Nature Communications(2025)10.1038/s41467-025-63762-y

N/A

0DataRank · unranked

1 citations

Robert Chen, David Stein, Joshua K. Park, Matthew Mort, Marie Verbanck +7 more

Dynamics of the most common pathogenic mtDNA variant m.3243A>G demonstrate frequency-dependency in blood and positive selection in the germline

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.26.433045

N/A

0DataRank · unranked

5 citations

Sarah J. Pickett, Zoë Fleischmann, Mark Khrapko, Auden Cote‐L’Heureux, Dylan Aidlen +9 more