Jianhan Chen

Biochemistry, Genetics and Molecular BiologyMaterials ScienceMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 41 papers. Top paper: “Hydrophobic gating in bundle-crossing ion channels: a case study of TRPV4”.

Hydrophobic gating in bundle-crossing ion channels: a case study of TRPV4

Communications Biology(2023)10.1038/s42003-023-05471-0

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0.435DataRank · unranked

11 citations

Jianhan Chen, Jian Huang

Targeting Intrinsically Disordered Proteins through Dynamic Interactions

Biomolecules(2020)10.3390/biom10050743

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0DataRank · unranked

54 citations

Xiaorong Liu, Jianhan Chen, Jianlin Chen

Specific PIP 2 Binding Promotes Calcium Activation of TMEM16A Chloride Channels

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.13.039743

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0DataRank · unranked

1 citations

Jianhan Chen, Zhiguang Jia

Nonspecific membrane interactions can modulate BK channel activation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.05.936161

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0DataRank · unranked

0 citations

Guohui Zhang, Zhiguang Jia, Jingyi Shi, Jianmin Cui, Jianhan Chen +1 more

Cancer-Associated Mutations Perturb the Structure and Interactions of the Intrinsically Disordered p53 Transactivation Domain

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.12.422504

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0DataRank · unranked

0 citations

Indhujah Thevarajan, Xiaorong Liu, Om Prakash, Michal Žółkiewski, Jianhan Chen +1 more

EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction

Nature Communications(2021)10.1038/s41467-021-21258-5

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0DataRank · unranked

158 citations

Alan J. Blayney, Xiaorong Liu, Lauren Gandy, Weihua Jin, Lufeng Yan +14 more

Specific PIP2 binding promotes calcium activation of TMEM16A chloride channels

Communications Biology(2021)10.1038/s42003-021-01782-2

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44 citations

Jianhan Chen, Zhiguang Jia

Advanced Sampling Methods for Multiscale Simulation of Disordered Proteins and Dynamic Interactions

Biomolecules(2021)10.3390/biom11101416

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37 citations

Yumeng Zhang, Jianhan Chen, Xiping Gong

Cancer-Associated Mutations Perturb the Disordered Ensemble and Interactions of the Intrinsically Disordered p53 Transactivation Domain

Journal of Molecular Biology(2021)10.1016/j.jmb.2021.167048

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0DataRank · unranked

27 citations

Xiaorong Liu, Indhujah Thevarajan, Om Prakash, Michal Žółkiewski, Jianhan Chen +1 more

Physics-based modeling provides predictive understanding of selectively promiscuous substrate binding by Hsp70 chaperones

PLoS Computational Biology(2021)10.1371/journal.pcbi.1009567

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15 citations

Charles A. English, Eugenia M. Clérico, Woody Sherman, Lila M. Gierasch, Jianhan Chen +1 more

Intrinsically disordered N-terminal domain (NTD) of p53 interacts with mitochondrial PTP regulator Cyclophilin D

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.23.453429

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2 citations

Xinyue Liu, Alan J. Blayney, Yumeng Zhang, Lauren Gandy, Fuming Zhang +6 more

Intrinsically Disordered N-terminal Domain (NTD) of p53 Interacts with Mitochondrial PTP Regulator Cyclophilin D

Journal of Molecular Biology(2022)10.1016/j.jmb.2022.167552

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0DataRank · unranked

20 citations

Xinyue Liu, Alan J. Blayney, Yumeng Zhang, Lauren Gandy, Paige Olivia Mirsky +8 more

An allosteric modulator activates BK channels by perturbing coupling between Ca2+ binding and pore opening

Nature Communications(2022)10.1038/s41467-022-34359-6

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20 citations

Xianjin Xu, Zhiguang Jia, Yanyan Geng, Hongwu Liang, Jingyi Shi +8 more

Activation of TMEM16F by inner gate charged mutations and possible lipid/ion permeation mechanisms

Biophysical Journal(2022)10.1016/j.bpj.2022.08.011

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0DataRank · unranked

14 citations

Jian Huang, Jianhan Chen, Zhiguang Jia

Computationally-Aided Modeling of Hsp70–Client Interactions: Past, Present, and Future

The Journal of Physical Chemistry B(2022)10.1021/acs.jpcb.2c03806

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5 citations

Eugenia M. Clérico, Jianhan Chen, Lila M. Gierasch, Erik B. Nordquist

An allosteric agonist activates BK channels by perturbing coupling between Ca 2+ binding and pore opening

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.28.478270

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0DataRank · unranked

0 citations

Xianjin Xu, Zhiguang Jia, Yanyan Geng, Hongwu Liang, Jingyi Shi +8 more

Toward Accurate Simulation of Coupling between Protein Secondary Structure and Phase Separation

Journal of the American Chemical Society(2023)10.1021/jacs.3c09195

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0DataRank · unranked

61 citations

Shanlong Li, Xiping Gong, Jianhan Chen, Yumeng Zhang

Machine Learning Generation of Dynamic Protein Conformational Ensembles

Molecules(2023)10.3390/molecules28104047

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0DataRank · unranked

33 citations

Shrishti Barethiya, Erik B. Nordquist, Jianhan Chen, Lie Zheng

Inner pore hydration free energy controls the activation of big potassium channels

Biophysical Journal(2023)10.1016/j.bpj.2023.02.005

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0DataRank · unranked

27 citations

Zhiguang Jia, Jianhan Chen, Erik B. Nordquist

Re-Balancing Replica Exchange with Solute Tempering for Sampling Dynamic Protein Conformations

Journal of Chemical Theory and Computation(2023)10.1021/acs.jctc.2c01139

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20 citations

Xiaorong Liu, Jianhan Chen, Yumeng Zhang

Incorporating physics to overcome data scarcity in predictive modeling of protein function: A case study of BK channels

PLoS Computational Biology(2023)10.1371/journal.pcbi.1011460

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0DataRank · unranked

7 citations

Guohui Zhang, Shrishti Barethiya, Nathan Ji, Kelli White, Lu Han +5 more

Coupled binding and folding of disordered SPIN N-terminal region in myeloperoxidase inhibition

Frontiers in Molecular Biosciences(2023)10.3389/fmolb.2023.1130189

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0DataRank · unranked

4 citations

Xiaorong Liu, Jianhan Chen, Yumeng Zhang

Incorporating physics to overcome data scarcity in predictive modeling of protein function: a case study of BK channels

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.24.546384

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0DataRank · unranked

2 citations

Guohui Zhang, Shrishti Barethiya, Nathan Ji, Kelli White, Lu Han +5 more

Accurate Simulation of Coupling between Protein Secondary Structure and Liquid-Liquid Phase Separation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.22.554378

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0DataRank · unranked

1 citations

Shanlong Li, Xiping Gong, Jianhan Chen, Yumeng Zhang

Structural basis for hyperpolarization-dependent opening of human HCN1 channel

Nature Communications(2024)10.1038/s41467-024-49599-x

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0DataRank · unranked

34 citations

Jonathan Mount, Jian Huang, John Cowgill, Yongchang Chang, Kathleen Bickel +4 more

Targeting TRP channels: recent advances in structure, ligand binding, and molecular mechanisms

Frontiers in Molecular Neuroscience(2024)10.3389/fnmol.2023.1334370

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0DataRank · unranked

31 citations

Aron Korsunsky, Mahdieh Yazdani, Jianhan Chen, Jian Huang

Backbone interactions and secondary structures in phase separation of disordered proteins

Biochemical Society Transactions(2024)10.1042/bst20230618

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0DataRank · unranked

13 citations

Yumeng Zhang, Jianhan Chen, Shanlong Li

Small Molecule NS11021 Promotes BK Channel Activation by Increasing Inner Pore Hydration

Journal of Chemical Information and Modeling(2024)10.1021/acs.jcim.4c01012

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10 citations

Zhiguang Jia, Jianhan Chen, Erik B. Nordquist

Tracking flaviviral protease conformational dynamics by tuning single-molecule nanopore tweezers

Biophysical Journal(2024)10.1016/j.bpj.2024.11.017

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0DataRank · unranked

7 citations

Yumeng Zhang, Jacqueline Sharp, Sophia Clingman, Ly Nguyen, Jianhan Chen +2 more

Likely Overstabilization of Charge–Charge Interactions in CHARMM36m(w): A Case for a99SB-disp Water

The Journal of Physical Chemistry B(2024)10.1021/acs.jpcb.4c04777

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3 citations

Yumeng Zhang, Jianhan Chen, Xiping Gong

A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.24.586494

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0DataRank · unranked

2 citations

Can Özden, Kairong Dong, Oguz Can Koc, Ana P. Torres‐Ocampo, Noelle Dziedzic +10 more

Phosphorylation of α-Synuclein Fibrils at S129 Changes DNAJB1 Binding as Probed by Solid-State NMR

JACS Au(2025)10.1021/jacsau.5c01266

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0DataRank · unranked

4 citations

Dhanya S. Reselammal, Shanlong Li, Zhang Qing-ya, Gauri Velloor, Jianhan Chen +2 more

PIP2 regulation of TRPV4 channels: Binding sites and dynamic coupling

Biophysical Journal(2025)10.1016/j.bpj.2025.08.006

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0DataRank · unranked

1 citations

Jianhan Chen, Jian Huang

Editorial: Rising stars in molecular neuroscience - molecular signalling & pathways: 2022

Frontiers in Molecular Neuroscience(2025)10.3389/fnmol.2025.1586932

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1 citations

Jianhan Chen, Veronika Stoka

Atomistic Simulation of Voltage Activation of a Truncated BK Channel

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.08.631907

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0DataRank · unranked

0 citations

Jianhan Chen, Zhiguang Jia

Atomistic Simulation of Voltage Activation of a Truncated BK Channel

eLife(2025)10.7554/elife.105895.2

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0DataRank · unranked

0 citations

Jianhan Chen, Zhiguang Jia

Atomistic Simulation of Voltage Activation of a Truncated BK Channel

eLife(2025)10.7554/elife.105895.3

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0DataRank · unranked

0 citations

Jianhan Chen, Zhiguang Jia

A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation

Nature Communications(2025)10.1038/s41467-025-63249-w

N/A

0DataRank · unranked

0 citations

Can Özden, Kairong Dong, Oguz Can Koc, Ana P. Torres‐Ocampo, Noelle Dziedzic +10 more

Dynamic domain interactions encode possible CheA autophosphorylation mechanisms revealed by coarse-grained simulations

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.21.695815

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0DataRank · unranked

0 citations

Katherine Wahlbeck Lu-Diaz, Lynmarie K. Thompson, Jianhan Chen, Jian Huang

Bioinspired bio-voltage memristors

Nature Communications(2020)10.1038/s41467-020-15759-y

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0DataRank · unranked

257 citations

Xiaomeng Liu, Hongyan Gao, Joy E. Ward, Xiaorong Liu, Bing Yin +8 more

Overcoming Extrapolation Challenges of Deep Learning by Incorporating Physics in Protein Sequence-Function Modeling

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.09.687530

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0DataRank · unranked

0 citations

Jian Huang, Xiao Liu, Hui Guan, Jianhan Chen, Shrishti Barethiya