C. Dirk Keene

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

23.1Author DataRank

Indexed papers

21in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 21 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A multimodal cell census and atlas of the mammalian primary motor cortex

Nature(2021)10.1038/s41586-021-03950-0

Top 5%

4.3DataRank

Top 5%574 citations

BRAIN Initiative Cell Census Network (BICCN) Corresponding authors, Edward M. Callaway, Joseph R. Ecker, Z. Josh Huang, Ed S. Lein +252 more

Papers

Driven by 156 papers — median percentile 71. Top paper: “A multimodal cell census and atlas of the mammalian primary motor cortex”.

A multimodal cell census and atlas of the mammalian primary motor cortex

Nature(2021)10.1038/s41586-021-03950-0

Top 5%

4.3DataRank

Top 5%574 citations

BRAIN Initiative Cell Census Network (BICCN) Corresponding authors, Edward M. Callaway, Joseph R. Ecker, Z. Josh Huang, Ed S. Lein +252 more

A comparative atlas of single-cell chromatin accessibility in the human brain

Science(2023)10.1126/science.adf7044

Top 7%

3.2DataRank

Top 7%159 citations

Sebastian Preissl, Michael Miller, Nicholas D. Johnson, Zihan Wang, Henry Jiao +34 more

Single-cell DNA methylation and 3D genome architecture in the human brain

Science(2023)10.1126/science.adf5357

Top 7%

3.1DataRank

Top 7%158 citations

Jingtian Zhou, Anna Bartlett, Qiurui Zeng, Hanqing Liu, Rosa G. Castanon +34 more

Genetic variants and functional pathways associated with resilience to Alzheimer’s disease

Brain(2020)10.1093/brain/awaa209

N/A

3.0DataRank · unranked

144 citations

Emily R. Mahoney, Shubhabrata Mukherjee, Michael L. Lee, William S. Bush, Corinne D. Engelman +44 more

Comparative transcriptomics reveals human-specific cortical features

Science(2023)10.1126/science.ade9516

N/A

2.8DataRank · unranked

205 citations

Janet Song, David Exposito-Alonso, Hamsini Suresh, Nathan Castro-Pacheco, Fenna M. Krienen +39 more

Transcriptomic diversity of cell types across the adult human brain

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.12.511898

Top 8%

2.7DataRank

Top 8%97 citations

Rebecca D. Hodge, Alejandro Mossi Albiach, Lijuan Hu, Ka Wai Lee, Peter Lönnerberg +14 more

Evolution of cellular diversity in primary motor cortex of human, marmoset monkey, and mouse

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.31.016972

N/A

2.4DataRank · unranked

90 citations

Nikolas L. Jorstad, Qiwen Hu, Blue B. Lake, Wei Tian, Brian E. Kalmbach +99 more

Integrated multimodal cell atlas of Alzheimer’s disease

Research Square(2023)10.21203/rs.3.rs-2921860/v1

Top 11%

1.9DataRank

Top 11%65 citations

Kyle J. Travaglini, Jeannelle Ariza, Eitan S Kaplan, Brian Long, Victoria M. Rachleff +86 more

Concordance of Clinical Alzheimer Diagnosis and Neuropathological Features at Autopsy

Journal of Neuropathology & Experimental Neurology(2020)10.1093/jnen/nlaa014

Top 14%

1.4DataRank

Top 14%38 citations

Tyler Bonnett, Lilah M. Besser, Willa D. Brenowitz, Merilee Teylan, Charles Mock +6 more

Target cell-specific synaptic dynamics of excitatory to inhibitory neuron connections in supragranular layers of human neocortex

eLife(2023)10.7554/elife.81863

N/A

1.4DataRank · unranked

39 citations

Cristina Radaelli, Elliot R. Thomsen, Deja Monet, Thomas Chartrand, Nikolas L. Jorstad +32 more

Integrated platform for multiscale molecular imaging and phenotyping of the human brain

Science(2024)10.1126/science.adh9979

Top 17%

1.2DataRank

Top 17%52 citations

Ji Wang, Webster Guan, Lars Gjesteby, Dylan Pollack, Lee Kamentsky +24 more

Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy

Journal of Neuropathology & Experimental Neurology(2020)10.1093/jnen/nlaa153

N/A

1.2DataRank · unranked

71 citations

Timothy E. Richardson, Kurt Farrell, Megan A. Iida, Chan Foong, Ping Shang +52 more

GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia

Nature Genetics(2024)10.1038/s41588-024-01939-9

N/A

1.1DataRank · unranked

66 citations

Yuriko Katsumata, Erin L. Abner, Khine Zin Aung, Steven A. Claas, Qi Qiao +91 more

Comparative cellular analysis of motor cortex in human, marmoset and mouse

Nature(2021)10.1038/s41586-021-03465-8

N/A

1.0DataRank · unranked

818 citations

Nikolas L. Jorstad, Qiwen Hu, Blue B. Lake, Wei Tian, Brian E. Kalmbach +101 more

A single-cell based precision medicine approach using glioblastoma patient-specific models

npj Precision Oncology(2022)10.1038/s41698-022-00294-4

Top 23%

0.883DataRank

Top 23%55 citations

Abdullah H. Feroze, Samuel Emerson, Anca B. Mihalas, C. Dirk Keene, Patrick J. Cimino +7 more

Transcriptomic cytoarchitecture reveals principles of human neocortex organization

Science(2023)10.1126/science.adf6812

N/A

0.799DataRank · unranked

205 citations

Jennie Close, Nelson Johansen, Anna Marie Yanny, Eliza Barkan, Kyle J. Travaglini +38 more

Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex

Cell Reports(2021)10.1016/j.celrep.2021.108754

N/A

0.793DataRank · unranked

197 citations

Lucas T. Graybuck, Erik E. Hess, Joseph T. Mahoney, Yoshiko Kojima, Yi Ding +37 more

Longitudinal cognitive performance of Alzheimer's disease neuropathological subtypes

Alzheimer s & Dementia Translational Research & Clinical Interventions(2021)10.1002/trc2.12201

Top 27%

0.758DataRank

Top 27%15 citations

Laura E. Gibbons, Shubhabrata Mukherjee, Emily H. Trittschuh, David W. Fardo, Patricia A. Boyle +6 more

Clonal hematopoiesis is associated with protection from Alzheimer’s disease

Nature Medicine(2023)10.1038/s41591-023-02397-2

N/A

0.755DataRank · unranked

152 citations

Julia A. Belk, Max Jan, Yanyan Qi, Chloé Sarnowski, Sara A. Wirth +23 more

Patterns of CAG repeat instability in the central nervous system and periphery in Huntington’s disease and in spinocerebellar ataxia type 1

Human Molecular Genetics(2020)10.1093/hmg/ddaa139

N/A

0.742DataRank · unranked

140 citations

Larissa Arning, James V. Giordano, Pedram Razghandi, Marissa A Andrew, Tammy Gillis +19 more

Signature morphoelectric properties of diverse GABAergic interneurons in the human neocortex

Science(2023)10.1126/science.adf6484

N/A

0.727DataRank · unranked

126 citations

Rachel Dalley, Jeremy A. Miller, Thomas Chartrand, Jennie Close, Rusty Mann +95 more

Association of Traumatic Brain Injury with Late Life Neuropathological Outcomes in a Community-Based Cohort

Journal of Alzheimer s Disease(2023)10.3233/jad-221224

Top 29%

0.687DataRank

Top 29%21 citations

Melinda C. Power, Rod Walker, Raj G. Kumar, Alia Murphy, Caitlin S. Latimer +9 more

Morphoelectric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex

Science(2023)10.1126/science.adf0805

N/A

0.672DataRank · unranked

87 citations

Rachel Dalley, Jennie Close, Natalia A. Goriounova, Brian Lee, Rusty Mann +85 more

A peptide-centric quantitative proteomics dataset for the phenotypic assessment of Alzheimer’s disease

Scientific Data(2023)10.1038/s41597-023-02057-7

Top 31%

0.652DataRank

Top 31%25 citations

Jea Park, Deanna L. Plubell, Brian C. Searle, C. Dirk Keene, Eric B. Larson +11 more

The Need to Separate Chronic Traumatic Encephalopathy Neuropathology from Clinical Features

Journal of Alzheimer's Disease(2017)10.3233/jad-170654

N/A

0.641DataRank · unranked

71 citations

C. Dirk Keene, George Perry, Rudolph J. Castellani, Grant L. Iverson

Pathological tau drives ectopic nuclear speckle scaffold protein SRRM2 accumulation in neuron cytoplasm in Alzheimer’s disease

Acta Neuropathologica Communications(2021)10.1186/s40478-021-01219-1

N/A

0.633DataRank · unranked

67 citations

Timothy J. Strovas, Misa Baum, Brooke K. Mitchell, Randall J. Eck, Nzinga Hendricks +5 more

Comparative transcriptomics reveals human-specific cortical features

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.19.508480

N/A

0.613DataRank · unranked

24 citations

Janet Song, David Exposito-Alonso, Hamsini Suresh, Nathan J. Castro, Fenna M. Krienen +38 more

Genome-wide association study and functional validation implicates JADE1 in tauopathy

Acta Neuropathologica(2021)10.1007/s00401-021-02379-z

N/A

0.553DataRank · unranked

39 citations

SoongHo Kim, Natalia Han, Megan A. Iida, Elias Gonzalez, Marcos Otero‐García +84 more

Interpretable deep learning of myelin histopathology in age-related cognitive impairment

Acta Neuropathologica Communications(2022)10.1186/s40478-022-01425-5

N/A

0.542DataRank · unranked

36 citations

Gabriel A. Marx, Daniel Koenigsberg, Mary Sawyer, Megan A. Iida, Jamie M. Walker +59 more

Morpho-electric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.24.511199

N/A

0.540DataRank · unranked

14 citations

Rachel Dalley, Jennie Close, Natalia A. Goriounova, Brian R. Lee, Rusty Mann +83 more

Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes.

Neurobiology of Disease(2020)10.1016/j.nbd.2020.105148

N/A

0.537DataRank · unranked

22 citations

Timothy J. Strovas, Pamela J. McMillan, Ashley M. Jacobi, Mark A. Behlke, Aleen D. Saxton +4 more

Aβ and tau prions feature in the neuropathogenesis of Down syndrome

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2212954119

N/A

0.520DataRank · unranked

31 citations

Alison M. Maxwell, Erika Castillo, Atsushi Aoyagi, Caroline Graff, Martin Ingelsson +8 more

Longitudinal change in memory performance as a strong endophenotype for Alzheimer's disease

Alzheimer s & Dementia(2023)10.1002/alz.13508

Top 38%

0.506DataRank

Top 38%22 citations

Jaclyn M. Eissman, Shubhabrata Mukherjee, Michael L. Lee, Seo‐Eun Choi, Phoebe Scollard +28 more

Signature morpho-electric properties of diverse GABAergic interneurons in the human neocortex

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.08.515739

N/A

0.470DataRank · unranked

22 citations

Rachel Dalley, Jeremy A. Miller, Thomas Chartrand, Jennie Close, Rusty Mann +89 more

Epigenomic complexity of the human brain revealed by single-cell DNA methylomes and 3D genome structures

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.30.518285

Top 41%

0.468DataRank

Top 41%10 citations

Jingtian Zhou, Anna Bartlett, Qiurui Zeng, Hanqing Liu, Rosa G. Castanon +33 more

Detection of blood–brain barrier disruption in brains of patients with COVID-19, but no evidence of brain penetration by SARS-CoV-2

Acta Neuropathologica(2023)10.1007/s00401-023-02624-7

N/A

0.449DataRank · unranked

19 citations

Alexandra Tomasevich, Kofi Acheampong, Dylan L. Schaff, Sydney M. Shaffer, Jean-Pierre Dollé +9 more

Integrated platform for multi-scale molecular imaging and phenotyping of the human brain

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.13.484171

N/A

0.396DataRank · unranked

13 citations

Ji Wang, Webster Guan, Lars Gjesteby, Dylan Pollack, Lee Kamentsky +24 more

Adult onset pan-neuronal human tau tubulin kinase 1 expression causes severe cerebellar neurodegeneration in mice

Acta Neuropathologica Communications(2020)10.1186/s40478-020-01073-7

N/A

0.396DataRank · unranked

13 citations

Jeanna M. Wheeler, Rachel E. Gatlin, Laura M. Taylor, Tim Strovas, Misa Baum +6 more

Neuropathological correlates of vulnerability and resilience in the cerebellum in Alzheimer's disease

Alzheimer s & Dementia(2024)10.1002/alz.14428

N/A

0.385DataRank · unranked

12 citations

Nicola H. Chapman, Laura E. Gibbons, Julianne M. Geller, Nicholas Loeb, Siddhant Dharap +11 more

Signature morpho-electric, transcriptomic, and dendritic properties of extratelencephalic-projecting human layer 5 neocortical pyramidal neurons

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.02.365080

N/A

0.364DataRank · unranked

4 citations

Rebecca D. Hodge, Nikolas L. Jorstad, Scott F. Owen, Trygve E. Bakken, Rebecca de Frates +25 more

Cross-species consensus atlas of the primate basal ganglia

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.15.694496

Top 52%

0.330DataRank

Top 52%8 citations

Yuanyuan Fu, Matthew T. Schmitz, Alma Dubuc, Niklas Kempynck, Morgan Wirthlin +95 more

Author Correction: Comparative cellular analysis of motor cortex in human, marmoset and mouse

Nature(2022)10.1038/s41586-022-04562-y

N/A

0.317DataRank · unranked

5 citations

Nikolas L. Jorstad, Qiwen Hu, Blue B. Lake, Wei Tian, Brian E. Kalmbach +104 more

Mass‐tag barcoding for multiplexed analysis of human synaptosomes and other anuclear events

Cytometry Part A(2021)10.1002/cyto.a.24340

N/A

0.312DataRank · unranked

7 citations

Rosemary Fernandez, Kathleen S. Montine, Edward Fox, Dunja Mrdjen, Nadia Postupna +4 more

A single-cell based precision medicine approach using glioblastoma patient-specific models

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.13.426485

Top 56%

0.287DataRank

Top 56%4 citations

Abdullah Feroze, Samuel Emerson, Anca B. Mihalas, C. Dirk Keene, Patrick J. Cimino +7 more

Target cell-specific synaptic dynamics of excitatory to inhibitory neuron connections in supragranular layers of human neocortex

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.16.343343

N/A

0.269DataRank · unranked

5 citations

Cristina Radaelli, Elliot R. Thomsen, Deja Machen, Tom Chartrand, Nikolas L. Jorstad +32 more

Inter-individual variation in human cortical cell type abundance and expression

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.07.511366

N/A

0.269DataRank · unranked

5 citations

Saroja Somasundaram, Kyle J. Travaglini, Anna Marie Yanny, Maya Shumyatcher, Tamara Casper +25 more

Unveiling Resilience to Alzheimer’s Disease: Insights From Brain Regional Proteomic Markers

Neuroscience Insights(2023)10.1177/26331055231201600

Top 60%

0.247DataRank

Top 60%3 citations

Gennifer E. Merrihew, Eric B. Larson, Jea Park, Deanna L. Plubell, Edward J. Fox +7 more

Digital neuropathology of neurodegenerative disorders: Foundations, research advances, and future directions

Alzheimer s & Dementia(2025)10.1002/alz.70775

N/A

0.241DataRank · unranked

4 citations

Juan C. Vizcarra, Shivam Sharma, C. Dirk Keene, Charles L. White, Ain Kim +8 more

Deep learning-based cell type profiles reveal signatures of Alzheimer’s disease resilience and resistance

Brain(2025)10.1093/brain/awaf285

N/A

0.241DataRank · unranked

4 citations

Amalia Perna, Syed Bukhari, Yeasul Kim, Lei Xue, David Seong +9 more

TRAUMATIC MICROHEMORHAGES ARE NOT SYNONYMOUS WITH AXONAL INJURY

medRxiv(2024)10.1101/2024.10.21.24315697

N/A

0.208DataRank · unranked

3 citations

Heather Maioli, Karinn Sytsma, Amanda Kirkland, C. Dirk Keene, Ramon Diaz‐Arrastia +5 more

Single-cell Multiome Analysis of Chromatin State and Transcriptome in the Human Basal Ganglia

10.64898/2026.02.03.703645

N/A

0.208DataRank · unranked

3 citations

Kai Li, Yang Xie, Guojie Zhong, Jonathan A. Rink, Cindy Tatiana Báez-Becerra +55 more

Single‐cell landscape of sex‐specific drivers of Alzheimer's disease

Alzheimer s & Dementia(2025)10.1002/alz.71041

Top 65%

0.208DataRank

Top 65%3 citations

Kyle J. Travaglini, Mariano I. Gabitto, C. Dirk Keene, AR Dunn, Catherine C. Kaczorowski +7 more

Single-cell multiomic human brain atlas reveals regulatory drivers of cortical regionality

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.07.667992

Top 78%

0.104DataRank

Top 78%1 citations

Jinghui Song, Bing Yang, Chien-Ju Chen, Dinh Diep, Kimberly Y. Conklin +17 more

UC Irvine’s Brain Initiative Cell Atlas Network (BICAN) Brain Procurement Program for the Center for Multiomic Human Brain Cell Atlas Project

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.23.696304

Top 78%

0.104DataRank

Top 78%1 citations

Bryan M Tran, Ginny Wu, Zhiqun Tan, Elizabeth Mendoza, Miyoung Kim +44 more

Evaluating the association of APOE genotype and cognitive resilience in SuperAgers

medRxiv(2025)10.1101/2025.01.07.25320117

N/A

0.104DataRank · unranked

1 citations

Shubhabrata Mukherjee, Michael L. Lee, Seo‐Eun Choi, Phoebe Scollard, Brandon S. Klinedinst +35 more

Detection of astrocytic tau pathology facilitates recognition of chronic traumatic encephalopathy neuropathologic change

Acta Neuropathologica Communications(2022)10.1186/s40478-022-01353-4

N/A

0DataRank · unranked

38 citations

Abigail C. Bretzin, Edward B. Lee, Rebecca D. Folkerth, Lili‐Naz Hazrati, Diego Iacono +30 more

Aberrant splicing of PSEN2, but not PSEN1, in individuals with sporadic Alzheimer’s disease

Brain(2022)10.1093/brain/awac294

N/A

0DataRank · unranked

32 citations

Kathryn Gudsnuk, C. Dirk Keene, Thomas D. Bird, Suman Jayadev, Paul N. Valdmanis +1 more

Isoform-specific dysregulation of AMP-activated protein kinase signaling in a non-human primate model of Alzheimer's disease

Neurobiology of Disease(2021)10.1016/j.nbd.2021.105463

N/A

0DataRank · unranked

13 citations

Xueyan Zhou, Beth Uberseder, Jingyun Lee, Caitlin S. Latimer, Cristina M. Furdui +7 more

TDP-43 promotes tau accumulation and selective neurotoxicity in bigenic Caenorhabditis elegans

Disease Models & Mechanisms(2022)10.1242/dmm.049323

N/A

0DataRank · unranked

44 citations

Jade G. Stair, Joshua C. Hincks, Heather N. Currey, Thomas D. Bird, C. Dirk Keene +3 more

Theoretical impact of the AT(N) framework on dementia using a community autopsy sample

Alzheimer s & Dementia(2021)10.1002/alz.12348

N/A

0DataRank · unranked

13 citations

Caitlin S. Latimer, C. Dirk Keene, Joshua A. Sonnen, Wayne C. McCormick, James D. Bowen +4 more

Association of cerebral microvascular dysfunction and white matter injury in Alzheimer’s disease

GeroScience(2022)10.1007/s11357-022-00585-5

N/A

0DataRank · unranked

27 citations

Christopher D. Kroenke, Katie Anne Fopiano, Yanna Tian, Jessica A. Filosa, Larry S. Sherman +6 more

Association of day-of-injury plasma glial fibrillary acidic protein concentration and six-month posttraumatic stress disorder in patients with mild traumatic brain injury

Neuropsychopharmacology(2022)10.1038/s41386-022-01359-5

N/A

0DataRank · unranked

27 citations

Sonia Jain, Lindsay D. Nelson, Frederick K. Korley, Pratik Mukherjee, Xiaoying Sun +28 more

Differential Vulnerability of Hippocampal Subfields in Primary Age-Related Tauopathy and Chronic Traumatic Encephalopathy

Journal of Neuropathology & Experimental Neurology(2022)10.1093/jnen/nlac066

N/A

0DataRank · unranked

21 citations

Megan A. Iida, Jonathan D. Cherry, Alicia Casella, Thor D. Stein, Kevin F. Bieniek +56 more

Emotional Resilience Predicts Preserved White Matter Microstructure Following Mild Traumatic Brain Injury

Biological Psychiatry Cognitive Neuroscience and Neuroimaging(2022)10.1016/j.bpsc.2022.08.015

N/A

0DataRank · unranked

13 citations

Benjamin L. Brett, Eva Palacios, Esther L. Yuh, Ioanna Bourla, Jamie Wren-Jarvis +32 more

Multispectral LEDs Eliminate Lipofuscin-Associated Autofluorescence for Immunohistochemistry and CD44 Variant Detection by in Situ Hybridization in Aging Human, non-Human Primate, and Murine Brain

ASN NEURO(2022)10.1177/17590914221123138

N/A

0DataRank · unranked

6 citations

Katie-Anne Fopiano, Fatima Banine, Mariel Garcia, Xi Gong, C. Dirk Keene +4 more

Application of deep learning to understand resilience to Alzheimer's disease pathology

Brain Pathology(2021)10.1111/bpa.12974

N/A

0DataRank · unranked

16 citations

Caitlin S. Latimer, Jonathan C. Henriksen, Marian Blazes, Eric B. Larson, Paul K. Crane +3 more

COllaborative Neuropathology NEtwork Characterizing ouTcomes of TBI (CONNECT-TBI)

Acta Neuropathologica Communications(2021)10.1186/s40478-021-01122-9

N/A

0DataRank · unranked

24 citations

Jean-Pierre Dollé, Kamar E. Ameen‐Ali, Abigail C. Bretzin, Etty Cortés, John F. Crary +23 more

Aging‐related Alzheimer's disease‐like neuropathology and functional decline in captive vervet monkeys (Chlorocebus aethiops sabaeus)

American Journal of Primatology(2021)10.1002/ajp.23260

N/A

0DataRank · unranked

32 citations

Suzanne Craft, Caitlin S. Latimer, C. Dirk Keene, Thomas J. Montine, Thomas C. Register +5 more

Transcriptomic cytoarchitecture reveals principles of human neocortex organization

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.06.515349

N/A

0DataRank · unranked

15 citations

Jennie Close, Nelson Johansen, Anna Marie Yanny, Eliza Barkan, Kyle J. Travaglini +38 more

Does Data-Independent Acquisition Data Contain Hidden Gems? A Case Study Related to Alzheimer’s Disease

Journal of Proteome Research(2021)10.1021/acs.jproteome.1c00558

N/A

0DataRank · unranked

37 citations

Lilian R. Heil, Gennifer E. Merrihew, Jasmeer P. Chhatwal, Martin R. Farlow, Catriona McLean +11 more

The Delayed Neuropathological Consequences of Traumatic Brain Injury in a Community-Based Sample

Frontiers in Neurology(2021)10.3389/fneur.2021.624696

N/A

0DataRank · unranked

47 citations

Shannon E. Rose, Laura E. Gibbons, N Coleman, Leanne Hellstern, Kayla Ritchie +17 more

Signature morpho-electric, transcriptomic, and dendritic properties of human layer 5 neocortical pyramidal neurons

Neuron(2021)10.1016/j.neuron.2021.08.030

N/A

0DataRank · unranked

114 citations

Rebecca D Hodge, Nikolas L. Jorstad, Scott F. Owen, Rebecca de Frates, Anna Marie Yanny +26 more

Increased excitatory to inhibitory synaptic ratio in parietal cortex samples from individuals with Alzheimer’s disease

Nature Communications(2021)10.1038/s41467-021-22742-8

N/A

0DataRank · unranked

171 citations

Pietro Scaduto, Conor D. Cox, Anton Schulmann, Gary Lynch, Christine M. Gall +3 more

Diagnosing Level of Consciousness: The Limits of the Glasgow Coma Scale Total Score

Journal of Neurotrauma(2021)10.1089/neu.2021.0199

N/A

0DataRank · unranked

213 citations

Alice Barra, Nancy Temkin, Jason Barber, Brandon Foreman, Mary J. Vassar +24 more

Single-cell CUT&Tag analysis of chromatin modifications in differentiation and tumor progression

Nature Biotechnology(2021)10.1038/s41587-021-00865-z

N/A

0DataRank · unranked

213 citations

Scott N. Furlan, Anca B. Mihalas, Hatice S Kaya-Okur, Abdullah H. Feroze, Samuel Emerson +10 more

Traumatic Brain Injury and Risk of Neurodegenerative Disorder

Biological Psychiatry(2021)10.1016/j.biopsych.2021.05.025

N/A

0DataRank · unranked

412 citations

Raquel C. Gardner, Jonathan P. Godbout, Kristen Dams-O'Connor, C. Dirk Keene, Benjamin L. Brett

Aberrant DJ-1 expression underlies L-type calcium channel hypoactivity in tuberous sclerosis complex and Alzheimer’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.26.267260

N/A

0DataRank · unranked

0 citations

Ayse Uneri, Colin J. McArdle, Luisa P. Cacheaux, Hailey X. Egido‐Betancourt, Sanjeev V. Namjoshi +9 more

Tractography-Pathology Correlations in Traumatic Brain Injury: A TRACK-TBI Study

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.20.209668

N/A

0DataRank · unranked

2 citations

Cathrine Petersen, Diego Iacono, Christine L. Mac Donald, Pratik Mukherjee, André van der Kouwe +13 more

The prevalence, correlation, and co-occurrence of neuropathology in old age: harmonisation of 12 measures across six community-based autopsy studies of dementia

The Lancet Healthy Longevity(2023)10.1016/s2666-7568(23)00019-3

N/A

0DataRank · unranked

94 citations

Richard L. Merrick, Simon I. Hay, Dibya Himali, Jayandra J. Himali, Sally Hunter +17 more

Interindividual variation in human cortical cell type abundance and expression

Science(2023)10.1126/science.adf2359

N/A

0DataRank · unranked

75 citations

Saroja Somasundaram, Kyle J. Travaglini, Anna Marie Yanny, Maya Shumyatcher, Tamara Casper +25 more

Associations of Sex, Race, and Apolipoprotein E Alleles With Multiple Domains of Cognition Among Older Adults

JAMA Neurology(2023)10.1001/jamaneurol.2023.2169

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0DataRank · unranked

57 citations

Alex G. Contreras, Jaclyn M. Eissman, Shubhabrata Mukherjee, Michael L. Lee, Seo‐Eun Choi +88 more

Prevalence of and Risk Factors for Post-traumatic Headache in Civilian Patients After Mild Traumatic Brain Injury

Mayo Clinic Proceedings(2023)10.1016/j.mayocp.2023.02.026

N/A

0DataRank · unranked

53 citations

David W. Dodick, Jason Barber, Nancy Temkin, Catherine D. Chong, Jennifer S. Adler +23 more

Microglia specific deletion of miR-155 in Alzheimer’s disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizures

Journal of Neuroinflammation(2023)10.1186/s12974-023-02745-6

N/A

0DataRank · unranked

47 citations

Katherine E. Prater, Raymond Sanchez, Asad Beck, Jasmine L. Pathan, Stephanie Davidson +6 more

Single-cell analysis of chromatin silencing programs in development and tumor progression

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.04.282418

N/A

0DataRank · unranked

12 citations

Scott N. Furlan, Anca B. Mihalas, Hatice S Kaya-Okur, Abdullah H. Feroze, Samuel Emerson +10 more

Brain proteomic analysis implicates actin filament processes and injury response in resilience to Alzheimer’s disease

Nature Communications(2023)10.1038/s41467-023-38376-x

N/A

0DataRank · unranked

38 citations

Gennifer E. Merrihew, Eric B. Larson, Jea Park, Deanna L. Plubell, Edward J. Fox +7 more

Tau–RNA complexes inhibit microtubule polymerization and drive disease-relevant conformation change

Brain(2023)10.1093/brain/awad032

N/A

0DataRank · unranked

36 citations

Sarah J. Benbow, Rikki L. Uhrich, Aleen D. Saxton, Misa Baum, Timothy J. Strovas +7 more

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Alzheimer s & Dementia(2023)10.1002/alz.13507

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0DataRank · unranked

27 citations

Derek B. Archer, Shubhabrata Mukherjee, Michael L. Lee, Seo‐Eun Choi, Phoebe Scollard +27 more

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Journal of Visualized Experiments(2020)10.3791/60596

N/A

0DataRank · unranked

5 citations

Nadia Postupna, Alexandra Golubeva, C. Dirk Keene, Matt Kaeberlein, Joshua C. Russell

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Journal of Neuropathology & Experimental Neurology(2023)10.1093/jnen/nlac127

N/A

0DataRank · unranked

22 citations

Yamah Hamsafar, Charles L. White, Julie A. Schneider, R. Ross Reichard, Stefan Prokop +16 more

Alzheimer's Disease-Related Dementias Summit 2022: National Research Priorities for the Investigation of Post-Traumatic Brain Injury Alzheimer's Disease and Related Dementias

Journal of Neurotrauma(2023)10.1089/neu.2022.0514

N/A

0DataRank · unranked

22 citations

Hibah O. Awwad, Stuart W. Hoffman, Mary Jo Pugh, Victoria E. Johnson, C. Dirk Keene +7 more

Purification and Analysis of Caenorhabditis elegans Extracellular Vesicles

Journal of Visualized Experiments(2020)10.3791/60596-v

N/A

0DataRank · unranked

2 citations

Nadia Postupna, Alexandra Golubeva, C. Dirk Keene, Matt Kaeberlein, Joshua C. Russell

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Brain Communications(2023)10.1093/braincomms/fcad258

N/A

0DataRank · unranked

20 citations

Stephanie Barsoum, Jeanelle Ariza, Amber Nolan, Caitlin S. Latimer, C. Dirk Keene +3 more

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Biological Psychiatry Cognitive Neuroscience and Neuroimaging(2020)10.1016/j.bpsc.2020.10.008

N/A

0DataRank · unranked

24 citations

Esther L. Yuh, Sonia Jain, David O. Okonkwo, Christine L. Mac Donald, Harvey S. Levin +64 more

LATE-NC risk alleles (in TMEM106B, GRN, and ABCC9 genes) among persons with African ancestry

Journal of Neuropathology & Experimental Neurology(2023)10.1093/jnen/nlad059

N/A

0DataRank · unranked

18 citations

David W. Fardo, Lincoln M. P. Shade, James D. Bowen, Paul K. Crane, Gail P. Jarvik +94 more

Aberrant DJ-1 expression underlies L-type calcium channel hypoactivity in dendrites in tuberous sclerosis complex and Alzheimer’s disease

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2301534120

N/A

0DataRank · unranked

14 citations

Ayse Uneri, Colin J. McArdle, Zhiyong Deng, Hailey X. Egido-Betancourt, Luisa P. Cacheaux +13 more

Adipocyte-Derived Small Extracellular Vesicles from Patients with Alzheimer Disease Carry miRNAs Predicted to Target the CREB Signaling Pathway in Neurons

International Journal of Molecular Sciences(2023)10.3390/ijms241814024

N/A

0DataRank · unranked

11 citations

Ankush Bansal, Laura Reck Cechinel, Kayla Authelet, Madeleine Goldberg, Evan P. Nadler +9 more

Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology

eLife(2023)10.7554/elife.91398

N/A

0DataRank · unranked

8 citations

Henry F. J. Tregidgo, Benjamin Billot, Yaël Balbastre, Jonathan Williams-Ramirez, Rogeny Herisse +21 more

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Journal of Neuropathology & Experimental Neurology(2023)10.1093/jnen/nlad035

N/A

0DataRank · unranked

5 citations

Rhonda Mittenzwei, Jane B. Shofer, Kathryn P. Scherpelz, Desiree A. Marshall, Amber Nolan +4 more

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Scientific Reports(2023)10.1038/s41598-023-40683-8

N/A

0DataRank · unranked

4 citations

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The microvascular extracellular matrix in brains with Alzheimer’s disease neuropathologic change (ADNC) and cerebral amyloid angiopathy (CAA)

Fluids and Barriers of the CNS(2020)10.1186/s12987-020-00219-y

N/A

0DataRank · unranked

33 citations

Robert B. Vernon, Jasmine L. Pathan, C. Dirk Keene, Anthony J. Day, William A. Banks +2 more

Risk of Transmissibility From Neurodegenerative Disease-Associated Proteins: Experimental Knowns and Unknowns

Journal of Neuropathology & Experimental Neurology(2020)10.1093/jnen/nlaa109

N/A

0DataRank · unranked

34 citations

Ermias D. Belay, Eileen H. Bigio, Sebastian Brandner, Scott A. Brubaker, Byron Caughey +20 more

APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer’s Disease pathology

medRxiv(2023)10.1101/2023.07.20.23292771

N/A

0DataRank · unranked

5 citations

Yann Le Guen, Sunny Chen, Eun-Gyung Lee, Lesley Leong, John E. Gorzynski +18 more

Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.08.544050

N/A

0DataRank · unranked

4 citations

Henry F. J. Tregidgo, Benjamin Billot, Yaël Balbastre, Jonathan Williams-Ramirez, Rogeny Herisse +21 more

Clinician-judged hearing impairment and associations with neuropathologic burden

Neurology(2020)10.1212/wnl.0000000000010575

N/A

0DataRank · unranked

22 citations

Lilah M. Besser, Walter A. Kukull, C. Dirk Keene, M. Maria Glymour, Kristine Yaffe +1 more

Redefining transcriptional regulation of the APOE gene and its association with Alzheimer’s disease

PLoS ONE(2020)10.1371/journal.pone.0227667

N/A

0DataRank · unranked

51 citations

Jessica Tulloch, Sunny Chen, Lesley Leong, Aleen D. Saxton, Brian C. Kraemer +7 more

APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer’s disease pathology

Neuron(2024)10.1016/j.neuron.2024.01.008

N/A

0DataRank · unranked

41 citations

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Journal of neurosurgery(2024)10.3171/2023.11.jns231425

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0DataRank · unranked

38 citations

Young Moo Lee, Xiaoying Sun, Thomas A. van Essen, Mahmoud Elguindy, Patrick Belton +62 more

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Nature Communications(2024)10.1038/s41467-024-46437-y

N/A

0DataRank · unranked

36 citations

Chien-Ju Chen, Ho Suk Lee, Matthew Cai, Mahsa Nafisi, Richard Que +16 more

Co-registration of MALDI-MSI and histology demonstrates gangliosides co-localize with amyloid beta plaques in Alzheimer’s disease

Acta Neuropathologica(2024)10.1007/s00401-024-02759-1

N/A

0DataRank · unranked

23 citations

Shervin Pejhan, Stephen Pasternak, C. Dirk Keene, Qi Zhang, Shawn N. Whitehead +1 more

Suppression of eEF2 phosphorylation alleviates synaptic failure and cognitive deficits in mouse models of Down syndrome

Alzheimer s & Dementia(2024)10.1002/alz.13916

N/A

0DataRank · unranked

16 citations

Qian Yang, Xueyan Zhou, C. Dirk Keene, Alexey G. Ryazanov, Tao Ma +1 more

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Brain(2024)10.1093/brain/awae325

N/A

0DataRank · unranked

15 citations

Yuriko Katsumata, Xian Wu, Khine Zin Aung, David W. Fardo, Shelley L. Forrest +95 more

The application of in vitro ‐derived human neurons in neurodegenerative disease modeling

Journal of Neuroscience Research(2020)10.1002/jnr.24615

N/A

0DataRank · unranked

36 citations

Shannon E. Rose, Allison Knupp, Daniel A. Nicholson, C. Dirk Keene, Jessica E. Young +1 more

Biomarker‐Based Approach to α‐Synucleinopathies: Lessons from Neuropathology

Movement Disorders(2024)10.1002/mds.30028

N/A

0DataRank · unranked

17 citations

Lea T. Grinberg, Glenda M. Halliday, Irina Alafuzoff, Brittany N. Dugger, Shigeo Murayama +39 more

Data-independent acquisition proteomic analysis of the brain microvasculature in Alzheimer’s disease identifies major pathways of dysfunction and upregulation of cytoprotective responses

Fluids and Barriers of the CNS(2024)10.1186/s12987-024-00581-1

N/A

0DataRank · unranked

11 citations

Richard S. Johnson, Mamatha Damodarasamy, Michael J. MacCoss, C. Dirk Keene, William A. Banks +2 more

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Neurology(2024)10.1212/wnl.0000000000208060

N/A

0DataRank · unranked

10 citations

Caitlin S. Latimer, Paul K. Crane, María M. Corrada, Laura E. Gibbons, Eric B. Larson +4 more

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PLoS Genetics(2024)10.1371/journal.pgen.1011359

N/A

0DataRank · unranked

10 citations

Cassidy Danyko, Jenna Somberg, Eli J. Kaufman, Meredith M. Course, Nadia Postupna +4 more

Lewy body pathology modifies risk factors for cerebral amyloid angiopathy when comorbid with Alzheimer's disease pathology

Alzheimer s & Dementia(2024)10.1002/alz.13704

N/A

0DataRank · unranked

8 citations

James Bena, Babak Tousi, Kasia Gustaw Rothenberg, C. Dirk Keene, James B. Leverenz +1 more

Advancements in high-resolution 3D microscopy analysis of endosomal morphology in postmortem Alzheimer’s disease brains

Frontiers in Neuroscience(2024)10.3389/fnins.2023.1321680

N/A

0DataRank · unranked

6 citations

Charles A. Williams, Dale W. Hailey, Swati Mishra, Amanda Kirkland, C. Dirk Keene +4 more

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Neurobiology of Disease(2024)10.1016/j.nbd.2024.106542

N/A

0DataRank · unranked

5 citations

Mitchell D. Kilgore, Mehwish Anwer, Alexander Maxan, Dan Child, Thomas D. Bird +4 more

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Neuropathology(2024)10.1111/neup.13007

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0DataRank · unranked

4 citations

Rebecca A. Yoda, Suman Jayadev, Marie Y. Davis, Joshua C. Hincks, Nicole F. Liachko +7 more

Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology

eLife(2024)10.7554/elife.91398.4

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0DataRank · unranked

1 citations

Henry F. J. Tregidgo, Benjamin Billot, Yaël Balbastre, Jonathan Williams-Ramirez, Rogeny Herisse +21 more

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Research Square(2024)10.21203/rs.3.rs-4469965/v1

N/A

0DataRank · unranked

2 citations

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Co-registration of MALDI-MSI and histology demonstrates gangliosides co-localize with amyloid beta plaques in Alzheimer’s disease.

Research Square(2024)10.21203/rs.3.rs-3985371/v1

N/A

0DataRank · unranked

1 citations

Shervin Pejhan, Stephen Pasternak, C. Dirk Keene, Qi Zhang, Shawn N. Whitehead +1 more

Reviewer #1 (Public Review): Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology

(2024)10.7554/elife.91398.2.sa1

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0DataRank · unranked

0 citations

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Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology

eLife(2024)10.7554/elife.91398.2

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0DataRank · unranked

0 citations

Henry F. J. Tregidgo, Benjamin Billot, Yaël Balbastre, Jonathan William-Ramirez, Rogeny Herisse +21 more

Reviewer #2 (Public Review): Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology

(2024)10.7554/elife.91398.3.sa0

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0DataRank · unranked

0 citations

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Advancements in high-resolution 3D microscopy analysis of endosomal morphology in postmortem Alzheimer’s disease brains

UNC Libraries(2024)10.17615/m26f-4g69

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0DataRank · unranked

0 citations

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0DataRank · unranked

7 citations

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0DataRank · unranked

6 citations

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0DataRank · unranked

3 citations

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0DataRank · unranked

3 citations

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0DataRank · unranked

5 citations

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Alzheimer s & Dementia(2025)10.1002/alz.70734

N/A

0DataRank · unranked

4 citations

Lea T. Grinberg, Jared T. Ahrendsen, Thomas G. Beach, Kevin F. Bieniek, Rudolph J. Castellani +41 more

Novel modelling approaches to elucidate the genetic architecture of resilience to Alzheimer’s disease

Brain(2025)10.1093/brain/awaf106

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0DataRank · unranked

3 citations

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Brain Communications(2025)10.1093/braincomms/fcaf123

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0DataRank · unranked

1 citations

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1 citations

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Parkinsonism & Related Disorders(2025)10.1016/j.parkreldis.2025.108066

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0DataRank · unranked

1 citations

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0DataRank · unranked

1 citations

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Scientific Reports(2020)10.1038/s41598-020-66113-7

N/A

0DataRank · unranked

58 citations

Abigail G. Schindler, James S. Meabon, Mayumi Yagi, Melanie J. Herbert, William A. Banks +7 more

Huntingtin preserves mitochondrial genome integrity in neurons, which is impaired in Huntington’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.24.666629

N/A

0DataRank · unranked

1 citations

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Alzheimer s & Dementia(2025)10.1002/alz.70965

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0DataRank · unranked

0 citations

Nikita Shchankin, Leiana Fung, Nicha Puangmalai, Nemil Bhatt, Md. Anzarul Haque +5 more

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PLoS ONE(2025)10.1371/journal.pone.0338780

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0DataRank · unranked

0 citations

Takashi Fujimoto, Mamatha Damodarasamy, Riley Weaver, C. Dirk Keene, William A. Banks +3 more

Viable human brain microvessels for the study of aging and neurodegenerative diseases

Microvascular Research(2021)10.1016/j.mvr.2021.104282

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0DataRank · unranked

2 citations

Zin Z. Khaing, Jeffrey E. Hyde, C. Dirk Keene, Itay Bentov, William A. Banks +2 more

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Journal of Clinical Investigation(2020)10.1172/jci133982

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0DataRank · unranked

94 citations

Wenzhong Yang, Nicole P. Kasica, Xueyan Zhou, Xin Wang, Brenna C. Beckelman +5 more

Single-synapse analyses of Alzheimer’s disease implicate pathologic tau, DJ1, CD47, and ApoE

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.14.448240

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0DataRank · unranked

3 citations

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medRxiv(2021)10.1101/2021.08.30.21262847

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0DataRank · unranked

3 citations

Nicholas P. Reder, Can Koyuncu, Patrick Leo, Sarah Hawley, Hanhui Huang +18 more

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Research Square(2021)10.21203/rs.3.rs-785404/v1

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0DataRank · unranked

1 citations

C.N.R. Rao, Xueyan Zhou, C. Dirk Keene, Tao Ma, Jason A. Stewart +2 more

Spontaneous Isomerization of Asp387 in Tau is Diagnostic for Alzheimer’s Disease: An Endogenous Indicator of Reduced Autophagic Flux

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.21.440819

N/A

0DataRank · unranked

0 citations

Lilian R. Heil, Gennifer E. Merrihew, Jasmeer P. Chhatwal, Martin R. Farlow, Catriona McLean +10 more

LATE-NC staging in routine neuropathologic diagnosis: an update

Acta Neuropathologica(2022)10.1007/s00401-022-02524-2

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0DataRank · unranked

178 citations

Edward B. Lee, Matthew D. Cykowski, Irina Alafuzoff, Konstantinos Arfanakis, Johannes Attems +45 more

Sex differences in the genetic architecture of cognitive resilience to Alzheimer’s disease

Brain(2022)10.1093/brain/awac177

N/A

0DataRank · unranked

102 citations

Logan Dumitrescu, Emily R. Mahoney, Alexandra N. Smith, Shubhabrata Mukherjee, Michael L. Lee +48 more

Outcome Prediction in Patients with Severe Traumatic Brain Injury Using Deep Learning from Head CT Scans

Radiology(2022)10.1148/radiol.212181

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0DataRank · unranked

100 citations

Dooman Arefan, Jason Barber, Esther L. Yuh, Ava M. Puccio, Kerri Hochberger +24 more

Outcomes in Patients With Mild Traumatic Brain Injury Without Acute Intracranial Traumatic Injury

JAMA Network Open(2022)10.1001/jamanetworkopen.2022.23245

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0DataRank · unranked

75 citations

Robert M. Rodriguez, Jason Barber, Nancy Temkin, Amy J. Markowitz, Natalie Kreitzer +25 more

Employment and Economic Outcomes of Participants With Mild Traumatic Brain Injury in the TRACK-TBI Study

JAMA Network Open(2022)10.1001/jamanetworkopen.2022.19444

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0DataRank · unranked

69 citations

Seth A. Seabury, Nancy Temkin, Jason Barber, Anthony M. DiGiorgio, Amy J. Markowitz +25 more

Functional excitatory to inhibitory synaptic imbalance and loss of cognitive performance in people with Alzheimer’s disease neuropathologic change

Acta Neuropathologica(2022)10.1007/s00401-022-02526-0

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0DataRank · unranked

67 citations

Julie C. Lauterborn, Conor D. Cox, Anna Fracassi, Tommaso Zeppillo, Berenice A. Gutierrez +7 more

Trajectories of Insomnia in Adults After Traumatic Brain Injury

JAMA Network Open(2022)10.1001/jamanetworkopen.2021.45310

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0DataRank · unranked

52 citations

Jennifer S. Albrecht, Vincent F. Capaldi, Sonia Jain, Raquel C. Gardner, J. Kent Werner +30 more

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Nature Communications(2022)10.1038/s41467-022-30785-8

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0DataRank · unranked

47 citations

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