Alexander Poltorak

A. Poltorak, X. He, I. Smirnova, M.-Y. Liu, C. Van Huffel, X. Du, D. Birdwell, E. Alejos, M. Silva, B. Layton, B. Beutler, Howard Hughes Medical Institute and the Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75235–9050 USA. C. Galanos and M. Freudenberg, Max-Planck Institute für Immunobiologie, Freiburg, Germany. P. Ricciardi, CNR–Cellular and Molecular Pharmacology Center, Milan, Italy.

ORCID: 0000-0002-5375-6587

Immunology and MicrobiologyBiochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 16 papers. Top paper: “Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene”.

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

Science(1998)10.1126/science.282.5396.2085

N/A

1.3DataRank · unranked

7593 citations

Xiaolong He, Irina Smirnova, Mu-Ya Liu, Christophe Van Huffel, Xin Du +12 more

Flipping the Switch from Inflammation to Cell Death

Trends in Immunology(2020)10.1016/j.it.2020.06.007

N/A

0DataRank · unranked

11 citations

Alexander Poltorak, Hayley I. Muendlein

Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation

Cell Reports(2020)10.1016/j.celrep.2019.12.073

N/A

0DataRank · unranked

34 citations

Joseph Sarhan, Beiyun C. Liu, Wilson M. Connolly, Stephen A. Schworer, Irina Smirnova +8 more

ZBP1 promotes LPS-induced cell death and IL-1β release via RHIM-mediated interactions with RIPK1

Nature Communications(2021)10.1038/s41467-020-20357-z

N/A

0DataRank · unranked

108 citations

Wilson M. Connolly, Zoie Magri, Irina Smirnova, Vladimir Ilyukha, Avishekh Gautam +3 more

Endothelial STING controls T cell transmigration in an IFNI-dependent manner

JCI Insight(2021)10.1172/jci.insight.149346

N/A

0DataRank · unranked

63 citations

Gail Newton, Kuljeet Kaur, Francisco J. Carrillo‐Salinas, Sasha Smolgovsky, Abraham Bayer +6 more

Immunoprecipitation Strategies to Isolate RIPK1/RIPK3 Complexes in Mouse Macrophages

Current Protocols(2021)10.1002/cpz1.156

N/A

0DataRank · unranked

3 citations

Dingqiang Zhang, Alexander Poltorak, Hayley I. Muendlein, Alexei Degterev, Ioannis Siokas

Neutrophils and macrophages drive TNF-induced lethality via TRIF/CD14-mediated responses

Science Immunology(2022)10.1126/sciimmunol.add0665

N/A

0DataRank · unranked

44 citations

Wilson M. Connolly, James Cameron, David Jetton, Zoie Magri, Irina Smirnova +6 more

Cell death: All roads lead to mitochondria

Current Biology(2022)10.1016/j.cub.2022.07.025

N/A

0DataRank · unranked

31 citations

Alexander Poltorak

Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair

Cell(2024)10.1016/j.cell.2024.10.010

N/A

0DataRank · unranked

46 citations

Julien Mambu, Daniel F. R. Boehmer, Benedetta Sposito, Virginie Millet, Joshua de Sousa Casal +26 more

CD14 is a decision-maker between Fas-mediated death and inflammation

Cell Reports(2024)10.1016/j.celrep.2024.114685

N/A

0DataRank · unranked

10 citations

David Jetton, Hayley I. Muendlein, Wilson M. Connolly, Hunter Russell, Irina Smirnova +4 more

Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection

Cell Reports(2024)10.1016/j.celrep.2024.114641

N/A

0DataRank · unranked

7 citations

Hayley I. Muendlein, Wilson M. Connolly, Zoie Magri, Irina Smirnova, Rebecca Batorsky +4 more

STING promotes homeostatic maintenance of tissues and confers longevity with aging

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.04.588107

N/A

0DataRank · unranked

6 citations

Katherine B. Sulka, Machlan Sawden, Kimberly A. Carroll, Ronald D. Brown, Stephen C. Bunnell +5 more

TNF switches homeostatic efferocytosis to lytic caspase-8–dependent pyroptosis and IL-1β maturation

Science Immunology(2025)10.1126/sciimmunol.adq0043

N/A

0DataRank · unranked

13 citations

Wilson M. Connolly, Jamie L. Leiriao, Mei-An Nolan, Jennifer Judge, Irina Smirnova +3 more

MyD88 determines T cell fate through BCAP-PI3K signaling

The Journal of Immunology(2025)10.1093/jimmun/vkae037

N/A

0DataRank · unranked

4 citations

Zoie Magri, Hayley I. Muendlein, Alexander Poltorak, Pilar Alcaide, Abraham Bayer

Tregs epigenetically reprogrammed from autoreactive effector T cells mitigate established autoimmunity

JCI Insight(2025)10.1172/jci.insight.185581

N/A

0DataRank · unranked

1 citations

James Cameron, Hayley I. Muendlein, Mei-An Nolan, Jamie L. Leiriao, James H. Kim +3 more

Regulatory T cells epigenetically reprogrammed from autoreactive effector T cells mitigate established autoimmunity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.24.665398

N/A

0DataRank · unranked

0 citations

James Cameron, Hayley I. Muendlein, Mei-An Nolan, Jamie L. Leiriao, James H. Kim +3 more