Alessandro Aiuti

Also affiliated with IRCCS Ospedale San Raffaele, The San Raffaele Telethon Institute for Gene Therapy

Biochemistry, Genetics and Molecular BiologyMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 5%percentile

0.557Author DataRank

Indexed papers

5in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 5 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Inborn errors of immunity: Manifestation, treatment, and outcome—an ESID registry 1994–2024 report on 30,628 patients

Journal of Human Immunity(2025)10.70962/jhi.20250007

Top 35%

0.557DataRank

Top 35%22 citations

Mickaël Alligon, Michael H. Albert, Matthew Buckland, David Edgar, Benjamin Gathmann +94 more

Papers

Driven by 32 papers — median percentile 65. Top paper: “Autoantibodies against type I IFNs in patients with life-threatening COVID-19”.

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

Science(2020)10.1126/science.abd4585

N/A

11.9DataRank · unranked

2864 citations

Lindsey B. Rosen, Qian Zhang, Eleftherios Michailidis, Hans-Heinrich Hoffmann, Yu Zhang +95 more

Human genetic and immunological determinants of critical COVID-19 pneumonia

Nature(2022)10.1038/s41586-022-04447-0

N/A

7.6DataRank · unranked

393 citations

Paul Bastard, COVID Human Genetic Effort, Adem Karbuz, Adrian Gervais, Ahmad Abou Tayoun +95 more

Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia

The Journal of Experimental Medicine(2022)10.1084/jem.20220131

N/A

2.0DataRank · unranked

117 citations

Daniela Matuozzo, Jérémie Le Pen, Danyel Lee, Leen Moens, Takaki Asano +94 more

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19

Genome Medicine(2023)10.1186/s13073-023-01173-8

N/A

1.5DataRank · unranked

78 citations

Estelle Talouarn, Astrid Marchal, Peng Zhang, Jérémy Manry, Yoann Seeleuthner +95 more

Respiratory viral infections in otherwise healthy humans with inherited IRF7 deficiency

The Journal of Experimental Medicine(2022)10.1084/jem.20220202

N/A

1.1DataRank · unranked

56 citations

Zhiyong Liu, Qian Zhang, Marcela Moncada‐Vélez, Laura Covill, Peng Zhang +94 more

A Case of Two Adult Brothers with Wiskott-Aldrich Syndrome, One Treated with Gene Therapy and One with HLA-Identical Hematopoietic Stem Cell Transplantation

Journal of Clinical Immunology(2022)10.1007/s10875-021-01157-6

N/A

1.0DataRank · unranked

11 citations

Francesca Ferrua, Pina Brianti, Jacopo Peccatori, Sarah Markel, Fabio Giglio +21 more

X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19

Science Immunology(2021)10.1126/sciimmunol.abl4348

N/A

0.907DataRank · unranked

422 citations

Bertrand Boisson, Fanny Onodi, Daniela Matuozzo, Marcela Moncada‐Vélez, Majistor Raj Luxman Maglorius Renkilaraj +95 more

A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection

Cell(2020)10.1016/j.cell.2020.05.016

N/A

0.820DataRank · unranked

235 citations

Helen C. Su, Laurent Abel, Alessandro Aiuti, Saleh Al‐Muhsen, Andrés A. Arias +59 more

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2200413119

N/A

0.794DataRank · unranked

198 citations

Paul Bastard, Adrian Gervais, Tom Le Voyer, Jérémie Rosain, Quentin Philippot +95 more

Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis in ∼40% of patients

The Journal of Experimental Medicine(2023)10.1084/jem.20230661

N/A

0.722DataRank · unranked

122 citations

Francesca Rovida, Maria Antonietta Avanzini, Stefania Croce, Astrid Marchal, Shih‐Ching Lin +57 more

Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency

Nature(2023)10.1038/s41586-023-06717-x

N/A

0.704DataRank · unranked

108 citations

Audrey V. Parent, Xian Liu, Axel Cederholm, Adrian Gervais, Jérémie Rosain +95 more

Inherited and acquired errors of type I interferon immunity govern susceptibility to COVID-19 and multisystem inflammatory syndrome in children

Journal of Allergy and Clinical Immunology(2023)10.1016/j.jaci.2023.02.003

N/A

0.610DataRank · unranked

16 citations

Laurent Abel, Salah Al-Muhsen, Alessandro Aiuti, Fahd Al‐Mulla, Evangelos Andreakos +70 more

Humans with inherited MyD88 and IRAK-4 deficiencies are predisposed to hypoxemic COVID-19 pneumonia

The Journal of Experimental Medicine(2023)10.1084/jem.20220170

N/A

0.606DataRank · unranked

56 citations

Rebeca Pérez de Diego, Carlos Flores, Darawan Rinchai, Jordi Solé‐Violán, Àngela Deyà‐Martínez +92 more

Hematopoietic stem cell transplantation for adolescents and adults with inborn errors of immunity: an EBMT IEWP study

Blood(2022)10.1182/blood.2022015506

N/A

0.606DataRank · unranked

56 citations

Tiarlan Sirait, Dirk-Jan Eikema, Katerina Bakunina, Claudia Wehr, Felipe Suarez +65 more

Harnessing Type I IFN Immunity Against SARS-CoV-2 with Early Administration of IFN-β

Journal of Clinical Immunology(2021)10.1007/s10875-021-01068-6

N/A

0.574DataRank · unranked

45 citations

Laurent Abel, Paul Bastard, Matthew P. Cheng, Antônio Condino‐Neto, Peter K. Gregersen +30 more

Impact of SARS-CoV-2 infection and COVID-19 on patients with inborn errors of immunity

Journal of Allergy and Clinical Immunology(2022)10.1016/j.jaci.2022.11.010

N/A

0.561DataRank · unranked

41 citations

Laurent Abel, Salah Al-Muhsen, Alessandro Aiuti, Saleh Al‐Muhsen, Fahd Al‐Mulla +63 more

Inborn errors of immunity: Manifestation, treatment, and outcome—an ESID registry 1994–2024 report on 30,628 patients

Journal of Human Immunity(2025)10.70962/jhi.20250007

Top 35%

0.557DataRank

Top 35%22 citations

Mickaël Alligon, Michael H. Albert, Matthew Buckland, David Edgar, Benjamin Gathmann +94 more

Long-term and real-world safety and efficacy of retroviral gene therapy for adenosine deaminase deficiency

Nature Medicine(2024)10.1038/s41591-023-02789-4

N/A

0.494DataRank · unranked

26 citations

Federica Barzaghi, Claudia Fossati, Paola M. V. Rancoita, Michela Gabaldo, Francesca Dionisio +49 more

The risk of COVID-19 death is much greater and age-dependent with type I IFN autoantibodies

Research Square(2022)10.21203/rs.3.rs-1225906/v1

N/A

0.483DataRank · unranked

24 citations

Paul Bastard, Adrian Gervais, Tom Le Voyer, Jérémie Rosain, Quentin Philippot +95 more

A common form of dominant human IFNAR1 deficiency impairs IFN-α and -ω but not IFN-β-dependent immunity

The Journal of Experimental Medicine(2024)10.1084/jem.20241413

N/A

0.396DataRank · unranked

13 citations

Jérémie Le Pen, Nicole A. de Weerd, Marcela Moncada‐Vélez, Marie Materna, Daniel Chieh-Ding Lin +89 more

Heterozygous BTNL8 variants in individuals with multisystem inflammatory syndrome in children (MIS-C)

The Journal of Experimental Medicine(2024)10.1084/jem.20240699

N/A

0.373DataRank · unranked

11 citations

David Santillo, Pierre Vantourout, Heather Jackson, Amédine Duret, Henry J. Hearn +93 more

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19

medRxiv(2022)10.1101/2022.10.22.22281221

N/A

0.360DataRank · unranked

10 citations

Estelle Talouarn, Astrid Marchal, Jérémy Manry, Yoann Seeleuthner, Yu Zhang +95 more

Lack of association between classical HLA genes and asymptomatic SARS-CoV-2 infection

Human Genetics and Genomics Advances(2024)10.1016/j.xhgg.2024.100300

N/A

0.306DataRank · unranked

6 citations

Elizabeth T. Cirulli, Iva Neveux, Evangelos Bellos, Ryan S. Thwaites, Kelly M. Schiabor Barrett +79 more

Outcome of BCG Vaccination in ADA-SCID Patients: A 12-Patient Series

Biomedicines(2023)10.3390/biomedicines11071809

N/A

0.256DataRank · unranked

4 citations

Chiara Oltolini, Federica Barzaghi, Valeria Calbi, Maddalena Migliavacca, Francesca Tucci +18 more

The seven enigmas of SARS-CoV-2: From the past to the future

Journal of Human Immunity(2025)10.70962/jhi.20250149

N/A

0.208DataRank · unranked

3 citations

Lisa M. Arkin, Paul Bastard, Alexandre Bolze, A. Borghesi, Petter Brodin +64 more

Gene therapy for Wiskott-Aldrich syndrome: History, new vectors, future directions

Journal of Allergy and Clinical Immunology(2020)10.1016/j.jaci.2020.06.018

N/A

0DataRank · unranked

47 citations

Francesco Marangoni, Alessandro Aiuti, Maria Grazia Roncarolo, Francesca Ferrua

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Science Immunology(2021)10.1126/sciimmunol.abl4340

N/A

0DataRank · unranked

634 citations

Adrian Gervais, Tom Le Voyer, Jérémie Rosain, Quentin Philippot, Jérémy Manry +95 more

From Your Nose to Your Toes: A Review of Severe Acute Respiratory Syndrome Coronavirus 2 Pandemic‒Associated Pernio

Journal of Investigative Dermatology(2021)10.1016/j.jid.2021.05.024

N/A

0DataRank · unranked

28 citations

John J. Moon, Jennifer M. Tran, Samira Asgari, Cliona O’Farrelly, Jean-Laurent Casanova +54 more

Autoantibodies against type I IFNs in patients with critical influenza pneumonia

The Journal of Experimental Medicine(2022)10.1084/jem.20220514

N/A

0DataRank · unranked

130 citations

Andrés Pizzorno, Lisa Miorin, Paul Bastard, Adrian Gervais, Tom Le Voyer +95 more

Severe West Nile Virus and Severe Acute Respiratory Syndrome Coronavirus 2 Infections in a Patient With Thymoma and Anti–Type I Interferon Antibodies

The Journal of Infectious Diseases(2024)10.1093/infdis/jiae321

N/A

0DataRank · unranked

9 citations

Camilla Visconti, Giovanni Battista Pipitone, Simone Bondesan, Giulia Molli, Stefania Giannelli +14 more

SARS-CoV-2–related MIS-C: A key to the viral and genetic causes of Kawasaki disease?

The Journal of Experimental Medicine(2021)10.1084/jem.20210446

N/A

0DataRank · unranked

150 citations

Petter Brodin, Aurélie Cobat, Catherine M. Biggs, Julie Toubiana, C. Lucas +95 more

Deleterious variants in the autophagy-related gene RB1CC1/FIP200 impair immunity to SARS-CoV-2

Nature Communications(2025)10.1038/s41467-025-65308-8

N/A

0DataRank · unranked

3 citations

Renée M. van der Sluis, Kennith Brian Castelino, Bao‐cun Zhang, Andreas Ronit, Thomas Zillinger +95 more

Alessandro Aiuti

Indexed papers

Top data-sharing exemplar

Papers