Jeffrey Milbrandt

Also affiliated with Washington University in St. Louis, Celldex Therapeutics (United States)

NeuroscienceBiochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 3%percentile

1.1Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

From karyotypes to precision genomics in 9p deletion and duplication syndromes

Human Genetics and Genomics Advances(2021)10.1016/j.xhgg.2021.100081

Top 24%

0.827DataRank

Top 24%25 citations

Jeffrey K. Ng, Victoria Tate, Ying‐Chen Claire Hou, Yang Cao, Lucinda Antonacci-Fulton +8 more

Papers

Driven by 50 papers — median percentile 59. Top paper: “Functional Mapping of Receptor Specificity Domains of Glial Cell Line-derived Neurotrophic Factor (GDNF) Family Ligands and Production of GFRα1 RET-specific Agonists”.

Functional Mapping of Receptor Specificity Domains of Glial Cell Line-derived Neurotrophic Factor (GDNF) Family Ligands and Production of GFRα1 RET-specific Agonists

Journal of Biological Chemistry(2000)10.1074/jbc.275.5.3412

N/A

4.0DataRank · unranked

64 citations

Malú G. Tansey, Eugene M. Johnson, Jeffrey Milbrandt, Robert H. Baloh

From karyotypes to precision genomics in 9p deletion and duplication syndromes

Human Genetics and Genomics Advances(2021)10.1016/j.xhgg.2021.100081

Top 24%

0.827DataRank

Top 24%25 citations

Jeffrey K. Ng, Victoria Tate, Ying‐Chen Claire Hou, Yang Cao, Lucinda Antonacci-Fulton +8 more

Products of gut microbial Toll/interleukin-1 receptor domain NADase activities in gnotobiotic mice and Bangladeshi children with malnutrition

Cell Reports(2022)10.1016/j.celrep.2022.110738

N/A

0.702DataRank · unranked

14 citations

Mark A. Zaydman, Siddarth Venkatesh, Yo Sasaki, Neha Damaraju, Alex L. Yenkin +9 more

Whole-genome sequencing reveals individual and cohort level insights into chromosome 9p syndromes

Genome Medicine(2025)10.1186/s13073-025-01563-0

Top 58%

0.269DataRank

Top 58%5 citations

Eleanor I. Sams, Rachel Slaugh, Sandra Crocker, Emily Cordova Hurtado, Sophia Tracy +66 more

Cell-autonomous expression of the acid hydrolase galactocerebrosidase

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1917675117

N/A

0DataRank · unranked

15 citations

Joshua T. Dearborn, Bruno A. Benítez, Amy Strickland, Lin Liu, Jeffrey Milbrandt +2 more

High-throughput single-cell functional elucidation of neurodevelopmental disease–associated genes reveals convergent mechanisms altering neuronal differentiation

Genome Research(2020)10.1101/gr.262295.120

N/A

0DataRank · unranked

100 citations

Denis Avey, Joseph D. Dougherty, Jeffrey Milbrandt, Robi D. Mitra, Matthew A. Lalli

Rapid and extraction-free detection of SARS-CoV-2 from saliva with colorimetric LAMP

medRxiv(2020)10.1101/2020.05.07.20093542

N/A

0DataRank · unranked

77 citations

S. Joshua Langmade, Xuhua Chen, Catrina C. Fronick, Christopher S. Sawyer, Lauren C. Burcea +8 more

SARM1 depletion rescues NMNAT1 dependent photoreceptor cell death and retinal degeneration

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.30.069385

N/A

0DataRank · unranked

4 citations

Hiroki Kakita, Shunsuke Kubota, Abdoulaye Sène, Tae Jun Lee, Norimitsu Ban +8 more

SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration

Neuron(2021)10.1016/j.neuron.2021.02.009

N/A

0DataRank · unranked

339 citations

Weixi Gu, Jeffrey D. Nanson, Yun Shi, Yo Sasaki, Katie Cunnea +20 more

Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN

The Journal of Cell Biology(2021)10.1083/jcb.202106080

N/A

0DataRank · unranked

90 citations

Maria F. Pazyra‐Murphy, Daina Avizonis, Mariana De Sa Tavares Russo, Sophia Tang, Chiung-Ya Chen +10 more

Live imaging reveals the cellular events downstream of SARM1 activation

eLife(2021)10.7554/elife.71148

N/A

0DataRank · unranked

74 citations

Laura Devault, Yo Sasaki, Jeffrey Milbrandt, Aaron DiAntonio, Kwang Woo Ko

SARM1 is required in human derived sensory neurons for injury-induced and neurotoxic axon degeneration

Experimental Neurology(2021)10.1016/j.expneurol.2021.113636

N/A

0DataRank · unranked

50 citations

Yo Sasaki, Aaron DiAntonio, Jeffrey Milbrandt, Yi‐Hsien Chen

Neurotoxins subvert the allosteric activation mechanism of SARM1 to induce neuronal loss

Cell Reports(2021)10.1016/j.celrep.2021.109872

N/A

0DataRank · unranked

42 citations

Jian Zhu, Amy Strickland, Kwang Woo Ko, Yo Sasaki, Caitlin B. Dingwall +8 more

Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection

Experimental Neurology(2021)10.1016/j.expneurol.2021.113842

N/A

0DataRank · unranked

37 citations

Jian Zhu, Yun Shi, Weixi Gu, Boštjan Kobe, Thomas Ve +3 more

The SARM1 TIR NADase: Mechanistic Similarities to Bacterial Phage Defense and Toxin-Antitoxin Systems

Frontiers in Immunology(2021)10.3389/fimmu.2021.752898

N/A

0DataRank · unranked

19 citations

Jeffrey Milbrandt, Matthew D. Figley, Aaron DiAntonio

Constitutively active SARM1 variants found in ALS patients induce neuropathy

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.16.439886

N/A

0DataRank · unranked

13 citations

Xianrong Mao, Amy Strickland, Yo Sasaki, Jeffrey Milbrandt, Aaron DiAntonio +1 more

Neurotoxins subvert the allosteric activation mechanism of SARM1 to induce neuronal loss

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.16.452689

N/A

0DataRank · unranked

7 citations

Jian Zhu, Amy Strickland, Kwang Woo Ko, Yo Sasaki, Caitlin B. Dingwall +8 more

Activation of Sarm1 produces cADPR to increase intra-axonal calcium and promote axon degeneration in CIPN

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.15.440024

N/A

0DataRank · unranked

4 citations

Maria F. Pazyra‐Murphy, Daina Avizonis, Mariana De Sa Tavares Russo, Sophia Tang, Johann S. Bergholz +8 more

Live Imaging Reveals the Cellular Events Downstream of SARM1 Activation

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.14.448297

N/A

0DataRank · unranked

3 citations

Jeffrey Milbrandt, Aaron DiAntonio, Kwang Woo Ko

Measuring Transcription Factor Binding and Gene Expression using Barcoded Self-Reporting Transposon Calling Cards and Transcriptomes

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.15.439516

N/A

0DataRank · unranked

0 citations

Allen Yen, Urvashi Thopte, Fengping Dong, Arnav Moudgil, Xuhua Chen +4 more

Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling

Science(2022)10.1126/science.adc8969

N/A

0DataRank · unranked

161 citations

Yun Shi, Sulin Li, Mark A. Zaydman, Neha Damaraju, Samuel Eastman +24 more

Structural basis of SARM1 activation, substrate recognition, and inhibition by small molecules

Molecular Cell(2022)10.1016/j.molcel.2022.03.007

N/A

0DataRank · unranked

142 citations

Philip S. Kerry, Jeffrey D. Nanson, Todd Bosanac, Yo Sasaki, Raul Krauss +20 more

Constitutively active SARM1 variants that induce neuropathy are enriched in ALS patients

Molecular Neurodegeneration(2022)10.1186/s13024-021-00511-x

N/A

0DataRank · unranked

120 citations

Xianrong Mao, Amy Strickland, Yo Sasaki, Jeffrey Milbrandt, Aaron DiAntonio +1 more

Loss of Stathmin-2, a hallmark of TDP-43-associated ALS, causes motor neuropathy

Cell Reports(2022)10.1016/j.celrep.2022.111001

N/A

0DataRank · unranked

119 citations

Amy Strickland, Yurie Yamada, Laura DeVault, Robert E. Schmidt, A. Joseph Bloom +3 more

A SARM1-mitochondrial feedback loop drives neuropathogenesis in a Charcot-Marie-Tooth disease type 2A rat model

Journal of Clinical Investigation(2022)10.1172/jci161566

N/A

0DataRank · unranked

56 citations

Amy Strickland, Yo Sasaki, A. Joseph Bloom, Aaron DiAntonio, Jeffrey Milbrandt +1 more

Macrophage depletion blocks congenital SARM1-dependent neuropathy

Journal of Clinical Investigation(2022)10.1172/jci159800

N/A

0DataRank · unranked

35 citations

Amy Strickland, Sabrina W. Yum, Aldrin Kay‐Yuen Yim, Jian Zhu, Peter L. Wang +7 more

Measuring transcription factor binding and gene expression using barcoded self-reporting transposon calling cards and transcriptomes

NAR Genomics and Bioinformatics(2022)10.1093/nargab/lqac061

N/A

0DataRank · unranked

7 citations

Allen Yen, Urvashi Thopte, Fengping Dong, Arnav Moudgil, Xuhua Chen +4 more

Distinct developmental and degenerative functions of SARM1 require NAD+ hydrolase activity

PLoS Genetics(2022)10.1371/journal.pgen.1010246

N/A

0DataRank · unranked

12 citations

Kow Essuman, Xianrong Mao, John Palucki, Yo Sasaki, Jeffrey Milbrandt +2 more

Loss of Stathmin-2, a hallmark of TDP-43-associated ALS, causes motor neuropathy

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.13.484188

N/A

0DataRank · unranked

13 citations

Amy Strickland, Yurie Yamada, Laura DeVault, Robert E. Schmidt, A. Joseph Bloom +3 more

Disruption of lactate metabolism in the peripheral nervous system leads to motor-selective deficits

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.29.497865

N/A

0DataRank · unranked

9 citations

Amber R. Hackett, Amy Strickland, Yurie Yamada, Joseph E. Ippolito, Robert E. Schmidt +4 more

Macrophage depletion blocks congenital SARM1-dependent neuropathy

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.26.482110

N/A

0DataRank · unranked

8 citations

Amy Strickland, Sabrina W. Yum, Aldrin Kay‐Yuen Yim, Jian Zhu, Peter L. Wang +7 more

Chemical structures of cyclic ADP ribose (cADPR) isomers and the molecular basis of their production and signaling

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.07.491051

N/A

0DataRank · unranked

7 citations

Yun Shi, Sulin Li, Mark A. Zaydman, Neha Damaraju, Samuel Eastman +23 more

The structure of NAD+ consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105290

N/A

0DataRank · unranked

3 citations

O. Juliet, Yajing Wang, Gabrielle Glendening, Jahid Carr, Constantine Tsibouris +18 more

The structure of NAD + consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.19.541320

N/A

0DataRank · unranked

0 citations

O. Juliet, Yajing Wang, Gabrielle Glendening, Jahid Carr, Constantine Tsibouris +18 more

The response of Dual-leucine zipper kinase (DLK) to nocodazole: evidence for a homeostatic cytoskeletal repair mechanism

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.06.561227

N/A

0DataRank · unranked

0 citations

Chase Mateusiak, John Palucki, Michael R. Brent, Jeffrey Milbrandt, Aaron DiAntonio +1 more

Sarm1 knockout prevents type 1 diabetic bone disease in females independent of neuropathy

JCI Insight(2024)10.1172/jci.insight.175159

N/A

0DataRank · unranked

10 citations

Ivana R. Shen, Clarissa S. Craft, Kristann Magee, Jay S. Park, Madelyn R. Lorenz +9 more

Synergistic Protection of Retinal Ganglion Cells (RGCs) by SARM1 Inactivation with CNTF in a Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy

Cells(2024)10.3390/cells13030202

N/A

0DataRank · unranked

6 citations

Zara Mehrabian, Jeffrey Milbrandt, Aaron DiAntonio, Steven L. Bernstein, Yan Guo

Two cardinal features of ALS, reduced STMN2 and pathogenic TDP-43, synergize to accelerate motor decline in mice

Experimental Neurology(2024)10.1016/j.expneurol.2024.115068

N/A

0DataRank · unranked

1 citations

Ana Morales Benitez, Amy Strickland, Jeffrey Milbrandt, A. Joseph Bloom, Aaron DiAntonio +1 more

Reduced STMN2 and pathogenic TDP-43, two hallmarks of ALS, synergize to accelerate motor decline in mice

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.19.585052

N/A

0DataRank · unranked

2 citations

Ana Morales Benitez, Amy Strickland, Jeffrey Milbrandt, A. Joseph Bloom, Aaron DiAntonio +1 more

Nicotinic acid riboside maintains NAD+ homeostasis and ameliorates aging-associated NAD+ decline

Cell Metabolism(2025)10.1016/j.cmet.2025.04.007

N/A

0DataRank · unranked

10 citations

Xiyu Shen, Kang Du, Cuauhtemoc B. Ramirez, Sang Hee Park, Yang Cao +22 more

Pmp2+ Schwann Cells Maintain the Survival of Large-Caliber Motor Axons

Journal of Neuroscience(2025)10.1523/jneurosci.1362-24.2025

N/A

0DataRank · unranked

7 citations

Amy Strickland, Ana Morales Benitez, Robert E. Schmidt, A. Joseph Bloom, Jeffrey Milbrandt +2 more

Peripheral nerve resident macrophages share tissue-specific programming and features of activated microglia

Nature Communications(2020)10.1038/s41467-020-16355-w

N/A

0DataRank · unranked

174 citations

Aldrin Kay‐Yuen Yim, Ki-Wook Kim, Denis Avey, Rafael S. Czepielewski, Marco Colonna +3 more

Suppressing phagocyte activation by overexpressing the phosphatidylserine lipase ABHD12 preserves sarmopathic nerves

iScience(2025)10.1016/j.isci.2025.112626

N/A

0DataRank · unranked

4 citations

Yo Sasaki, Amy Strickland, Tong Wu, Daniel W. Summers, A. Joseph Bloom +3 more

Diverse cell types establish a pathogenic immune environment in peripheral neuropathy

Journal of Neuroinflammation(2025)10.1186/s12974-025-03459-7

N/A

0DataRank · unranked

4 citations

Amy Strickland, Hui Qi Loo, Wendy Dong, Lilianne Barbar, A. Joseph Bloom +5 more

Shared TIR enzymatic functions regulate cell death and immunity across the tree of life

Carolina Digital Repository (University of North Carolina at Chapel Hill)(2025)10.17615/b9y8-v159

N/A

0DataRank · unranked

0 citations

Marc T. Nishimura, Jeffery L. Dangl, Jeffrey Milbrandt, Kow Essuman

Heterozygous and Homozygous RFC1 AAGGG Repeat Expansions are Common in Idiopathic Peripheral Neuropathy

medRxiv(2025)10.1101/2025.04.18.25325809

N/A

0DataRank · unranked

0 citations

Sinem Ovunc, Ryo Iwase, Elle Mehinovic, Simone Thomas, Jenna Ulibarri +11 more

Nicotinic acid riboside maintains NAD+ homeostasis and ameliorates aging-associated NAD+ decline

Cell Metabolism(2025)10.1016/j.cmet.2025.05.004

N/A

0DataRank · unranked

7 citations

Xiyu Shen, Kang Du, Cuauhtemoc B. Ramirez, Sang Hee Park, Yang Cao +22 more

SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration

The Journal of Cell Biology(2020)10.1083/jcb.201912047

N/A

0DataRank · unranked

142 citations

Jeffrey Milbrandt, Aaron DiAntonio, Kwang Woo Ko

Rapid and Extraction-Free Detection of SARS-CoV-2 from Saliva by Colorimetric Reverse-Transcription Loop-Mediated Isothermal Amplification

Clinical Chemistry(2020)10.1093/clinchem/hvaa267

N/A

0DataRank · unranked

243 citations

Joshua S Langmade, Xuhua Chen, Catrina C. Fronick, Christopher S. Sawyer, Lauren C. Burcea +8 more

cADPR is a gene dosage-sensitive biomarker of SARM1 activity in healthy, compromised, and degenerating axons

Experimental Neurology(2020)10.1016/j.expneurol.2020.113252

N/A

0DataRank · unranked

126 citations

Thomas M. Engber, Robert Hughes, Matthew D. Figley, Tong Wu, Todd Bosanac +5 more

Jeffrey Milbrandt

Indexed papers

Top data-sharing exemplar

Papers