Alexander R. Horswill

Also affiliated with University of Colorado Anschutz Medical Campus, University of Tübingen, University of Colorado Denver

MedicineBiochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 7%percentile

0.135Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

X-ray-driven chemistry and conformational heterogeneity in atomic resolution crystal structures of bacterial dihydrofolate reductases

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.07.566054

Top 71%

0.135DataRank

Top 71%1 citations

Alexander R. Horswill, Mark A. Wilson, Nathan Smith

Papers

Driven by 63 papers — median percentile 29. Top paper: “X-ray-driven chemistry and conformational heterogeneity in atomic resolution crystal structures of bacterial dihydrofolate reductases”.

X-ray-driven chemistry and conformational heterogeneity in atomic resolution crystal structures of bacterial dihydrofolate reductases

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.07.566054

Top 71%

0.135DataRank

Top 71%1 citations

Alexander R. Horswill, Mark A. Wilson, Nathan Smith

Staphylococcus epidermidis protease EcpA can be a deleterious component of the skin microbiome in atopic dermatitis

Journal of Allergy and Clinical Immunology(2020)10.1016/j.jaci.2020.06.024

N/A

0DataRank · unranked

186 citations

Michael R. Williams, Anna M. Butcher, Teruaki Nakatsuji, J.S. Kavanaugh, J Cheng +6 more

Staphylococcus aureus bloodstream infections: pathogenesis and regulatory mechanisms

Current Opinion in Microbiology(2020)10.1016/j.mib.2020.02.005

N/A

0DataRank · unranked

381 citations

Alexander R. Horswill, Jakub Kwieciński

Interplay of Staphylococcal and Host Proteases Promotes Skin Barrier Disruption in Netherton Syndrome

Cell Reports(2020)10.1016/j.celrep.2020.02.021

N/A

0DataRank · unranked

126 citations

Laura Cau, Yichen Wang, Drishti Kaul, James Sanford, Lívia S. Zaramela +8 more

Short chain fatty acids produced by Cutibacterium acnes inhibit biofilm formation by Staphylococcus epidermidis

Scientific Reports(2020)10.1038/s41598-020-77790-9

N/A

0DataRank · unranked

105 citations

Alan M. O’Neill, Michael R. Williams, Laura Cau, Teruaki Nakatsuji, Alexander R. Horswill +2 more

Investigation of synovial fluid induced Staphylococcus aureus aggregate development and its impact on surface attachment and biofilm formation

PLoS ONE(2020)10.1371/journal.pone.0231791

N/A

0DataRank · unranked

61 citations

Tripti Thapa Gupta, Devendra H. Dusane, Douglas V. Guzior, Amelia Staats, Jan Harro +3 more

Fighting Staphylococcus aureus infections with light and photoimmunoconjugates

JCI Insight(2020)10.1172/jci.insight.139512

N/A

0DataRank · unranked

22 citations

Andrea Anaya-Sanchez, Sabrina Suhani, Elisa J. M. Raineri, Marina López‐Álvarez, Marjolein Heuker +9 more

Cathepsin G Degrades Staphylococcus aureus Biofilms

The Journal of Infectious Diseases(2020)10.1093/infdis/jiaa612

N/A

0DataRank · unranked

21 citations

Kevin G. Leidal, William M. Nauseef, Alexander R. Horswill, J.S. Kavanaugh

Targeted and untargeted analysis of secondary metabolites to monitor growth and quorum sensing inhibition for methicillin-resistant Staphylococcus aureus (MRSA)

Journal of Microbiological Methods(2020)10.1016/j.mimet.2020.106000

N/A

0DataRank · unranked

8 citations

Lindsay K. Caesar, Chantal V. Pelzer, William J. Crandall, Christian Jenul, Daniel A. Todd +3 more

Stochastic Expression of Sae-Dependent Virulence Genes during Staphylococcus aureus Biofilm Development Is Dependent on SaeS

mBio(2020)10.1128/mbio.03081-19

N/A

0DataRank · unranked

34 citations

Derek E. Moormeier, Jennifer L. Endres, Rebecca E. Hodges, Marat R. Sadykov, Alexander R. Horswill +2 more

Intracellular Environment and agr System Affect Colony Size Heterogeneity of Staphylococcus aureus

Frontiers in Microbiology(2020)10.3389/fmicb.2020.01415

N/A

0DataRank · unranked

34 citations

Julian Bär, Vanina Dengler Haunreiter, Srikanth Mairpady Shambat, Kati Seidl, Heidi A. Crosby +3 more

Triterpenoid acids isolated from Schinus terebinthifolia fruits reduce Staphylococcus aureus virulence and abate dermonecrosis

Scientific Reports(2020)10.1038/s41598-020-65080-3

N/A

0DataRank · unranked

27 citations

Gina Porras, Morgan M. Brown, François Chassagne, James T. Lyles, John Bacsa +3 more

Staphylococcus aureus Aggregates on Orthopedic Materials under Varying Levels of Shear Stress

Applied and Environmental Microbiology(2020)10.1128/aem.01234-20

N/A

0DataRank · unranked

26 citations

Niraj Gupta, Matthew J. Pestrak, Devendra H. Dusane, Janette M. Harro, Alexander R. Horswill +2 more

Processing, Export, and Identification of Novel Linear Peptides from Staphylococcus aureus

mBio(2020)10.1128/mbio.00112-20

N/A

0DataRank · unranked

10 citations

Lindsay K. Caesar, Nadja B. Cech, Alexander R. Horswill, Katrin Schilcher

Correction: Investigation of synovial fluid induced Staphylococcus aureus aggregate development and its impact on surface attachment and biofilm formation

PLoS ONE(2020)10.1371/journal.pone.0233534

N/A

0DataRank · unranked

10 citations

Tripti Thapa Gupta, Devendra H. Dusane, Douglas V. Guzior, Amelia Staats, Jan Harro +3 more

MgrA regulates interaction of Staphylococcus aureus with mucin

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.09.035261

N/A

0DataRank · unranked

1 citations

Nour Akil, Cullen R. Shanrock, Patrick D. Allen, Anna Chaly, Heidi A. Crosby +4 more

Staphylococcus aureus uses the ArlRS and MgrA cascade to regulate immune evasion during skin infection

Cell Reports(2021)10.1016/j.celrep.2021.109462

N/A

0DataRank · unranked

73 citations

Rachel M. Kratofil, Corey P. Parlet, Bas G. J. Surewaard, Paul Kubes, Alexander R. Horswill +1 more

Basophil-derived IL-4 promotes cutaneous Staphylococcus aureus infection

JCI Insight(2021)10.1172/jci.insight.149953

N/A

0DataRank · unranked

32 citations

Mrinmoy Das, Jennifer Kane, Maria Strakosha, Sonal Singh, Daniel Sen Hoi Wong +5 more

Non-Native Peptides Capable of Pan-Activating the agr Quorum Sensing System across Multiple Specificity Groups of Staphylococcus epidermidis

ACS Chemical Biology(2021)10.1021/acschembio.1c00240

N/A

0DataRank · unranked

20 citations

Wenqi Shen, Emma L. Eisenbraun, Yang Tian, Joseph K. Vasquez, Alexander R. Horswill +2 more

Staphylococcus aureus Enters Hair Follicles Using Triacylglycerol Lipases Preserved through the Genus Staphylococcus

Journal of Investigative Dermatology(2021)10.1016/j.jid.2021.02.009

N/A

0DataRank · unranked

16 citations

Michael R. Williams, Jakub Kwieciński, Alexander R. Horswill, Richard L. Gallo, Kouki Nakamura

Castaneroxy A From the Leaves of Castanea sativa Inhibits Virulence in Staphylococcus aureus

Frontiers in Pharmacology(2021)10.3389/fphar.2021.640179

N/A

0DataRank · unranked

13 citations

Gina Porras, Young-Saeng K. Cho, Morgan M. Brown, Caitlin J. Risener, Lewis Marquez +5 more

Human monoclonal antibodies against Staphylococcus aureus surface antigens recognize in vitro biofilm and in vivo implant infections

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.09.429966

N/A

0DataRank · unranked

4 citations

Bruce van Dijk, Kok P. M. van Kessel, J.S. Kavanaugh, Carla J. C. de Haas, Piet C. Aerts +16 more

The Ubiquitous Human Skin Commensal Staphylococcus hominis Protects against Opportunistic Pathogens

mBio(2022)10.1128/mbio.00930-22

N/A

0DataRank · unranked

111 citations

Michael R. Williams, Ali Shahbandi, Zoie L. Bunch, Laurie M. Lyon, Amber Nguyen +7 more

The influenza-injured lung microenvironment promotes MRSA virulence, contributing to severe secondary bacterial pneumonia

Cell Reports(2022)10.1016/j.celrep.2022.111721

N/A

0DataRank · unranked

43 citations

K. Oshima, Sarah A. McMurtry, Yimu Yang, Jakub Kwieciński, Wells B. LaRivière +13 more

Therapeutic Inhibition of Staphylococcus aureus ArlRS Two-Component Regulatory System Blocks Virulence

Antimicrobial Agents and Chemotherapy(2022)10.1128/aac.00187-22

N/A

0DataRank · unranked

32 citations

Diamond A. Jelani, Ernesto J. Fuentes, Alexander R. Horswill, Jakub Kwieciński

Overcoming pH defenses on the skin to establish infections

PLoS Pathogens(2022)10.1371/journal.ppat.1010512

N/A

0DataRank · unranked

30 citations

Alexander R. Horswill, Flavia G. Costa

The staphylococcal biofilm protein Aap mediates cell–cell adhesion through mechanically distinct homophilic and lectin interactions

PNAS Nexus(2022)10.1093/pnasnexus/pgac278

N/A

0DataRank · unranked

22 citations

Constance Chantraine, Albertus Viljoen, Andrew B. Herr, Paul D. Fey, Alexander R. Horswill +3 more

Rapid Aggregation of Staphylococcus aureus in Synovial Fluid Is Influenced by Synovial Fluid Concentration, Viscosity, and Fluid Dynamics, with Evidence of Polymer Bridging

mBio(2022)10.1128/mbio.00236-22

N/A

0DataRank · unranked

24 citations

Peter W. Burback, Andrew Schwieters, Dan Li, Anne C. Sullivan, Alexander R. Horswill +2 more

Group B Streptococcus Adaptation Promotes Survival in a Hyperinflammatory Diabetic Wound Environment

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.27.497804

N/A

0DataRank · unranked

2 citations

Amanda L. Haeberle, Christophe Langouët-Astrié, J.S. Kavanaugh, Eric P. Schmidt, Garrett D. Moore +3 more

Host-derived protease promotes aggregation of Staphylococcus aureus by cleaving the surface protein SasG

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.13.520364

N/A

0DataRank · unranked

1 citations

Klara C. Keim, Jakub Kwieciński, Christophe Langouët-Astrié, K. Oshima, Wells B. LaRivière +3 more

S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis

Cell(2023)10.1016/j.cell.2023.10.019

N/A

0DataRank · unranked

144 citations

Flavia G. Costa, Kimbria J. Blake, Samantha Choi, Arundhasa Chandrabalan, Muhammad Saad Yousuf +19 more

Pyochelin biotransformation by Staphylococcus aureus shapes bacterial competition with Pseudomonas aeruginosa in polymicrobial infections

Cell Reports(2023)10.1016/j.celrep.2023.112540

N/A

0DataRank · unranked

42 citations

Klara C. Keim, Justin N. Jens, Michael J. Zeiler, Katrin Schilcher, Michael J. Schurr +4 more

Staphylococcus epidermidis activates keratinocyte cytokine expression and promotes skin inflammation through the production of phenol-soluble modulins

Cell Reports(2023)10.1016/j.celrep.2023.113024

N/A

0DataRank · unranked

42 citations

Michelle D. Bagood, Timothy J. Enroth, Zoie L. Bunch, Nina Jiang, Edward Liu +8 more

Itaconate-producing neutrophils regulate local and systemic inflammation following trauma

JCI Insight(2023)10.1172/jci.insight.169208

N/A

0DataRank · unranked

37 citations

Sonya Ostashevskaya-Gohstand, Stefano Comazzetto, Jessica S. Hook, Lei Guo, Neda Vishlaghi +8 more

Aging-Associated Augmentation of Gut Microbiome Virulence Capability Drives Sepsis Severity

mBio(2023)10.1128/mbio.00052-23

N/A

0DataRank · unranked

18 citations

Joshua M. Kirsch, Christopher L. Erzen, Christophe Langouët-Astrié, Grace E. Thompson, Sarah A. McMurtry +14 more

The impact of nutritional immunity on Group B streptococcal pathogenesis during wound infection

mBio(2023)10.1128/mbio.00304-23

N/A

0DataRank · unranked

15 citations

Rebecca A. Keogh, Jana N. Radin, Yamil Sanchez-Rosario, Michael D. L. Johnson, Alexander R. Horswill +4 more

Identifying genetic determinants of Streptococcus pyogenes-host interactions in a murine intact skin infection model

Cell Reports(2023)10.1016/j.celrep.2023.113332

N/A

0DataRank · unranked

15 citations

Christophe Langouët-Astrié, Morgan M. Severn, Michael J. Federle, Alexander R. Horswill, Reid V. Wilkening

In Vitro Staphylococcal Aggregate Morphology and Protection from Antibiotics Are Dependent on Distinct Mechanisms Arising from Postsurgical Joint Components and Fluid Motion

Journal of Bacteriology(2023)10.1128/jb.00451-22

N/A

0DataRank · unranked

8 citations

Peter W. Burback, Nadia N. Casillas-Ituarte, Dan Li, Michaela R. Hostetler, Anne C. Sullivan +4 more

A structure activity relationship study of 3,4′-dimethoxyflavone for ArlRS inhibition in Staphylococcus aureus

Organic & Biomolecular Chemistry(2023)10.1039/d3ob00123g

N/A

0DataRank · unranked

6 citations

Patrick M. O'Conner, Jakub Kwieciński, Orry M. Marciano, Angelica Nunag, Andrew T. Gutierrez +4 more

Bi-fluorescent Staphylococcus aureus infection enables single-cell analysis of intracellular killing in vivo

Frontiers in Immunology(2023)10.3389/fimmu.2023.1089111

N/A

0DataRank · unranked

2 citations

Sonia S. Laforce‐Nesbitt, Joshua T. Cohen, Miles Mundy, Joseph M. Bliss, Alexander R. Horswill +2 more

Mechanistic basis of staphylococcal interspecies competition for skin colonization

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.26.525635

N/A

0DataRank · unranked

9 citations

Constance Chantraine, Krista B. Mills, Rahul Yadav, Alexander E. Yarawsky, Catherine T. Chaton +8 more

Staphylococcus aureus skin colonization is mediated by SasG lectin variation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.20.567970

N/A

0DataRank · unranked

4 citations

J.J. Maciag, Can Wang, John A. Crawford, Timothy J. Enroth, Klara C. Keim +6 more

The Staphylococcus aureus regulatory program in a human skin-like environment

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.24.563767

N/A

0DataRank · unranked

1 citations

Krista B. Mills, Heidi A. Crosby, Alexander R. Horswill, Flavia G. Costa

Aging-associated augmentation of gut microbiome virulence capability drives sepsis severity

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.10.523523

N/A

0DataRank · unranked

0 citations

Joshua M. Kirsch, Christopher L. Erzen, Christophe Langouët-Astrié, Grace E. Thompson, Sarah A. McMurtry +14 more

Rgg2/Rgg3 quorum sensing is a determinant of Streptococcus pyogenes -host interactions in a murine intact skin infection model

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.14.549100

N/A

0DataRank · unranked

0 citations

Christophe Langouët-Astrié, Morgan M. Severn, Michael J. Federle, Alexander R. Horswill, Reid V. Wilkening

The role of human extracellular matrix proteins in defining Staphylococcus aureus biofilm infections

FEMS Microbiology Reviews(2024)10.1093/femsre/fuae002

N/A

0DataRank · unranked

66 citations

Alexander R. Horswill, Mohini Bhattacharya

The Staphylococcus aureus regulatory program in a human skin-like environment

mBio(2024)10.1128/mbio.00453-24

N/A

0DataRank · unranked

40 citations

Krista B. Mills, Heidi A. Crosby, Alexander R. Horswill, Flavia G. Costa

Staphylococcus aureus skin colonization is mediated by SasG lectin variation

Cell Reports(2024)10.1016/j.celrep.2024.114022

N/A

0DataRank · unranked

19 citations

J.J. Maciag, Can Wang, John A. Crawford, Timothy J. Enroth, Klara C. Keim +6 more

Synthetic Peptides Capable of Potent Multigroup Staphylococcal Quorum Sensing Activation and Inhibition in Both Cultures and Biofilm Communities

Journal of the American Chemical Society(2024)10.1021/jacs.4c02694

N/A

0DataRank · unranked

17 citations

Troy D. Vulpis, Brendan N. Prosser, Alexander R. Horswill, Helen E. Blackwell, Emma L. Eisenbraun

Virulence characteristics of Gram-positive bacteria isolated from diabetic foot ulcers

FEMS Microbes(2024)10.1093/femsmc/xtae013

N/A

0DataRank · unranked

15 citations

Savannah Huyvaert, Garrett D. Moore, Alexander R. Horswill, Kelly S. Doran, Rebecca A. Keogh

Micrococcal nuclease regulates biofilm formation and dispersal in methicillin-resistant Staphylococcus aureus USA300

mSphere(2024)10.1128/msphere.00126-24

N/A

0DataRank · unranked

9 citations

Alexander R. Horswill, Jeffrey B. Kaplan

The Staphylococcus aureus CamS lipoprotein is a repressor of toxin production that shapes host-pathogen interaction

PLoS Biology(2024)10.1371/journal.pbio.3002451

N/A

0DataRank · unranked

6 citations

Morgan M. Severn, Christian Jenul, Young-Saeng C. Avina, Rebecca A. Keogh, Alexander R. Horswill +1 more

Host-derived protease promotes aggregation of Staphylococcus aureus by cleaving the surface protein SasG

mBio(2024)10.1128/mbio.03483-23

N/A

0DataRank · unranked

5 citations

Klara C. Keim, Jakub Kwieciński, Christophe Langouët-Astrié, K. Oshima, Wells B. LaRivière +3 more

Polymicrobial interactions between Staphylococcus aureus and Pseudomonas aeruginosa promote biofilm formation and persistence in chronic wound infections

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.11.04.621402

N/A

0DataRank · unranked

13 citations

Mohini Bhattacharya, Heidi A. Crosby, Christian Jenul, Krista B. Mills, Michael J. Schurr +2 more

Collagen binding adhesin restricts Staphylococcus aureus skin infection

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.11.01.621145

N/A

0DataRank · unranked

6 citations

Brady L. Spencer, Jakub Kwieciński, Magdalena Podkowik, Gregory Putzel, Alejandro Pironti +4 more

Androgens at the skin surface regulate S. aureus pathogenesis through the activation of agr quorum sensing

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.10.579753

N/A

0DataRank · unranked

2 citations

Mahendran Chinnappan, Methinee Artami, Mohini Bhattacharya, Rebecca A. Keogh, J.S. Kavanaugh +4 more

Global genome analysis identifies glycolipids and lipoteichoic acid alanylation as contributors to group B streptococcal diabetic wound infection

Cell Reports(2025)10.1016/j.celrep.2025.116510

N/A

0DataRank · unranked

4 citations

Madeline S. Akbari, Dustin T. Nguyen, Brady L. Spencer, Jeremy Rahkola, Kevin S. McIver +4 more

Genome-wide mutagenesis identifies factors involved in MRSA vaginal colonization

Cell Reports(2025)10.1016/j.celrep.2025.115421

N/A

0DataRank · unranked

5 citations

Stephanie M Marroquin, John C Thorstenson, Luke R. Joyce, Ernesto J. Fuentes, Kelly S. Doran +2 more

Staphylococcus aureus accessory gene regulator quorum-sensing system inhibits keratinocyte lipid enzymes and delays wound repair

Journal of Clinical Investigation(2025)10.1172/jci190411

N/A

0DataRank · unranked

3 citations

Jelena Marjanović, Nina Jiang, Hung Chan, Tatsuya Dokoshi, Kellen Cavagnero +9 more

Mutation in Staphylococcus aureus that supports gain of function in susceptibility both to hypochlorous acid and to human neutrophils

Journal of Leukocyte Biology(2025)10.1093/jleuko/qiaf057

N/A

0DataRank · unranked

2 citations

Katrin Schilcher, J. Kavanaugh, Alexander R. Horswill, William M. Nauseef, Athmane Teghanemt

Global genome analysis identifies glycolipids and lipoteichoic acid alanylation as contributors to Group B streptococcal diabetic wound infection

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.02.651901

N/A

0DataRank · unranked

1 citations

Madeline S. Akbari, Dustin T. Nguyen, Brady L. Spencer, Jeremy Rahkola, Kevin S. McIver +4 more

Staphylococcus epidermidis—Skin friend or foe?

PLoS Pathogens(2020)10.1371/journal.ppat.1009026

N/A

0DataRank · unranked

189 citations

Alexander R. Horswill, Morgan M. Brown

GAS Regulation of Zinc Homeostasis During Skin and Soft Tissue Infection

DOAJ (DOAJ: Directory of Open Access Journals)(2025)10.3390/proceedings2025124017

N/A

0DataRank · unranked

0 citations

Lindsey R. Burcham, Laura Cook, Alexander R. Horswill, Reid V. Wilkening

Alexander R. Horswill

Indexed papers

Top data-sharing exemplar

Papers