Kristopher T. Kahle

Also affiliated with Boston Children's Hospital, Harvard University, Harvard University Press, Massachusetts General Hospital, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Mass General Brigham, Massachusetts Institute of Technology

NeuroscienceMedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 46 papers. Top paper: “The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus”.

The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus

Cell(2023)10.1016/j.cell.2023.01.017

N/A

2.7DataRank · unranked

145 citations

Benjamin C. Reeves, Emre Kiziltug, Phan Q. Duy, Jason K. Karimy, M. Shahid Mansuri +32 more

Modulation of brain cation-Cl− cotransport via the SPAK kinase inhibitor ZT-1a

Nature Communications(2020)10.1038/s41467-019-13851-6

N/A

0.716DataRank · unranked

117 citations

Mohammad Iqbal H. Bhuiyan, Ting Zhang, Jason K. Karimy, Zhijuan Wu, Victoria M. Fiesler +19 more

Rethinking the cilia hypothesis of hydrocephalus

Neurobiology of Disease(2022)10.1016/j.nbd.2022.105913

N/A

0.590DataRank · unranked

50 citations

Ana B.W. Greenberg, William E. Butler, Kristopher T. Kahle, Phan Q. Duy

Rare pathogenic variants in WNK3 cause X-linked intellectual disability

Genetics in Medicine(2022)10.1016/j.gim.2022.05.009

N/A

0.416DataRank · unranked

15 citations

Jinwei Zhang, Thomas Besnard, Alfonso Caro‐Llopis, Xue Zeng, Stephanie M. Robert +75 more

Angiographic Pulse Wave Coherence in the Human Brain

Frontiers in Bioengineering and Biotechnology(2022)10.3389/fbioe.2022.873530

N/A

0.372DataRank · unranked

6 citations

Phan Q. Duy, Benjamin L. Grannan, Aman B. Patel, Scott B. Raymond, Pankaj K. Agarwalla +3 more

AXIN1 mutations in nonsyndromic craniosynostosis

Journal of Neurosurgery Pediatrics(2024)10.3171/2024.5.peds24115

N/A

0.165DataRank · unranked

2 citations

Kshipra Hemal, Jonas A. Gustafson, Le Hao, Irene Valenzuela, Anne Slavotinek +5 more

PTEN mutations in autism spectrum disorder and congenital hydrocephalus: developmental pleiotropy and therapeutic targets

Trends in Neurosciences(2021)10.1016/j.tins.2021.08.007

N/A

0DataRank · unranked

42 citations

Marina Carlson, Shreyas Panchagnula, Stephanie M. Robert, Phan Q. Duy, Kellen Mermin‐Bunnell +10 more

Unique Actions of GABA Arising from Cytoplasmic Chloride Microdomains

Journal of Neuroscience(2021)10.1523/jneurosci.3175-20.2021

N/A

0DataRank · unranked

41 citations

Kieran P. Normoyle, Joseph Glykys, Volodymyr Dzhala, Kyle P. Lillis, Kristopher T. Kahle +4 more

Variants in ADD1 cause intellectual disability, corpus callosum dysgenesis, and ventriculomegaly in humans

Genetics in Medicine(2021)10.1016/j.gim.2021.09.014

N/A

0DataRank · unranked

19 citations

Irena Feng, Ana Rita Costa, Rita Pinto‐Costa, Jennifer E. Neil, Oana Caluseriu +21 more

Dual activating FGFR1 mutations in pediatric pilomyxoid astrocytoma

Molecular Genetics & Genomic Medicine(2021)10.1002/mgg3.1597

N/A

0DataRank · unranked

6 citations

Benjamin C. Reeves, William Sullivan, Asher Marks, Anita Hüttner, Kristopher T. Kahle +2 more

Analysis workflow to assess de novo genetic variants from human whole-exome sequencing

STAR Protocols(2021)10.1016/j.xpro.2021.100383

N/A

0DataRank · unranked

15 citations

Spencer B. king, Weilai Dong, Garrett Allington, Amar H. Sheth, Samuel T. Peters +3 more

Role of SPAK-NKCC1 Signaling Cascade in the Choroid Plexus Blood-CSF Barrier Damage After Stroke

Research Square(2021)10.21203/rs.3.rs-1189368/v1

N/A

0DataRank · unranked

1 citations

Ruijia Liu, Md Nabiul Hasan, Sydney Fischer, Matthew Como, Victoria M. Fiesler +12 more

Variants in ADD1 Cause Intellectual Disability, Corpus Callosum Dysgenesis, and Ventriculomegaly in Humans

SSRN Electronic Journal(2021)10.2139/ssrn.3931622

N/A

0DataRank · unranked

0 citations

Irena Feng, Ana Rita Costa, Rita Pinto‐Costa, Jennifer Neil, Oana Caluseriu +16 more

Brain ventricles as windows into brain development and disease

Neuron(2022)10.1016/j.neuron.2021.12.009

N/A

0DataRank · unranked

60 citations

Pasko Rakić, Seth L. Alper, William E. Butler, Christopher A. Walsh, Nenad Šestan +4 more

Role of SPAK–NKCC1 signaling cascade in the choroid plexus blood–CSF barrier damage after stroke

Journal of Neuroinflammation(2022)10.1186/s12974-022-02456-4

N/A

0DataRank · unranked

39 citations

Ruijia Liu, Md Nabiul Hasan, Sydney Fischer, Yang Chen, Matthew Como +12 more

A neural stem cell paradigm of pediatric hydrocephalus

Cerebral Cortex(2022)10.1093/cercor/bhac341

N/A

0DataRank · unranked

31 citations

Pasko Rakić, Seth L. Alper, Stephanie M. Robert, Adam J. Kundishora, William E. Butler +6 more

Computational Genomics in the Era of Precision Medicine: Applications to Variant Analysis and Gene Therapy

Journal of Personalized Medicine(2022)10.3390/jpm12020175

N/A

0DataRank · unranked

23 citations

Yuchang Wu, Julie Choi, Garrett Allington, Shujuan Zhao, Mariam Khanfar +12 more

De novo mutations in the BMP signaling pathway in lambdoid craniosynostosis

Human Genetics(2022)10.1007/s00439-022-02477-2

N/A

0DataRank · unranked

19 citations

Emre Kiziltug, Sheng Chih Jin, Carol Nelson‐Williams, Erin Loring, August Allocco +17 more

Familial and syndromic forms of arachnoid cyst implicate genetic factors in disease pathogenesis

Cerebral Cortex(2022)10.1093/cercor/bhac257

N/A

0DataRank · unranked

17 citations

Kedous Y. Mekbib, Garrett Allington, Aladine A. Elsamadicy, Phan Q. Duy, Adam J. Kundishora +3 more

Somatic Ras/Raf/MAPK Variants Enriched in the Hippocampus in Drug-Resistant Mesial Temporal Lobe Epilepsy

medRxiv(2022)10.1101/2022.12.23.22283854

N/A

0DataRank · unranked

5 citations

Yilan Wang, Yasmine Chahine, E. Zeynep Erson‐Omay, Stephanie M. Robert, Emre Kiziltug +36 more

Cation flux through SUR1-TRPM4 and NCX1 in astrocyte endfeet induces water influx through AQP4 and brain swelling after ischemic stroke

Science Signaling(2023)10.1126/scisignal.add6364

N/A

0DataRank · unranked

54 citations

Bosung Shim, Serban Negoita, Natalya Tsymbalyuk, Orest Tsymbalyuk, Svetlana Ivanova +8 more

Rare variants in ANO1 , encoding a calcium-activated chloride channel, predispose to moyamoya disease

Brain(2023)10.1093/brain/awad172

N/A

0DataRank · unranked

26 citations

Wenlei Ye, Stuart Fraser, Jill A. Rosenfeld, Pavel N. Pichurin, Scott E. Hickey +19 more

Multiomic analyses implicate a neurodevelopmental program in the pathogenesis of cerebral arachnoid cysts

Nature Medicine(2023)10.1038/s41591-023-02238-2

N/A

0DataRank · unranked

20 citations

Garrett Allington, Stephen McGee, Kedous Y. Mekbib, Vladimir G. Gainullin, Andrew T. Timberlake +31 more

Mutation of key signaling regulators of cerebrovascular development in vein of Galen malformations

Nature Communications(2023)10.1038/s41467-023-43062-z

N/A

0DataRank · unranked

27 citations

Kedous Y. Mekbib, Martijn A. van der Ent, Garrett Allington, Andrew Prendergast, Jocelyn E. Chau +61 more

A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus

Brain(2023)10.1093/brain/awad405

N/A

0DataRank · unranked

18 citations

Garrett Allington, Stephen Viviano, Stephen McGee, Emre Kiziltug, Shaojie Ma +25 more

Molecular Diagnostic Yield of Exome Sequencing in Patients With Congenital Hydrocephalus

JAMA Network Open(2023)10.1001/jamanetworkopen.2023.43384

N/A

0DataRank · unranked

13 citations

Neel H. Mehta, Garrett Allington, Sheng Chih Jin, Andrés Moreno-De-Luca, Kristopher T. Kahle +1 more

Cases of familial idiopathic normal pressure hydrocephalus implicate genetic factors in disease pathogenesis

Cerebral Cortex(2023)10.1093/cercor/bhad374

N/A

0DataRank · unranked

9 citations

Neel H. Mehta, Kedous Y. Mekbib, Emre Kiziltug, Hannah Smith, Bradley T. Hyman +7 more

Neurosurgery elucidates somatic mutations

Science(2023)10.1126/science.adj2244

N/A

0DataRank · unranked

6 citations

Christopher A. Walsh, Kristopher T. Kahle, Eduardo A. Maury

De Novo Variants in RAB11B Cause Various Degrees of Global Developmental Delay and Intellectual Disability in Children

Pediatric Neurology(2023)10.1016/j.pediatrneurol.2023.08.023

N/A

0DataRank · unranked

4 citations

Walid Fazeli, Sophia Schließke, Gaëtan Lesca, Zeynep Gokce‐Samar, Kedous Y. Mekbib +26 more

Genetic dysregulation of an endothelial Ras signaling network in vein of Galen malformations

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.18.532837

N/A

0DataRank · unranked

3 citations

Kedous Y. Mekbib, Martijn A. van der Ent, Garrett Allington, Andrew Prendergast, Jocelyn E. Chau +58 more

A novel SMARCC1 -mutant BAFopathy implicates epigenetic dysregulation of neural progenitors in hydrocephalus

medRxiv(2023)10.1101/2023.03.19.23287455

N/A

0DataRank · unranked

1 citations

Stephen Viviano, Garrett Allington, Stephen McGee, Emre Kiziltug, Kedous Y. Mekbib +24 more

Paediatric hydrocephalus

Nature Reviews Disease Primers(2024)10.1038/s41572-024-00519-9

N/A

0DataRank · unranked

70 citations

Petra M. Klinge, Jenna E. Koschnitzky, Abhaya V. Kulkarni, Nanna MacAulay, Shenandoah Robinson +3 more

The genetic basis of hydrocephalus: genes, pathways, mechanisms, and global impact

Fluids and Barriers of the CNS(2024)10.1186/s12987-024-00513-z

N/A

0DataRank · unranked

27 citations

Hunter Boudreau, Rishi K. Devulapalli, Phan Q. Duy, Travis J. Atchley, Michael C. Dewan +13 more

TRIM71 mutations cause a neurodevelopmental syndrome featuring ventriculomegaly and hydrocephalus

Brain(2024)10.1093/brain/awae175

N/A

0DataRank · unranked

21 citations

Bettina Jux, Shujuan Zhao, Kedous Y. Mekbib, Evan Dennis, Weilai Dong +25 more

Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus

Cell Reports Medicine(2024)10.1016/j.xcrm.2024.101647

N/A

0DataRank · unranked

7 citations

Dibyanti Mukherjee, Massimo Bonora, Christoph P. Bagowski, Jeannette Nardelli, Livia Metani +34 more

De novo variants disrupt an LDB1 -regulated transcriptional network in congenital ventriculomegaly

Brain(2024)10.1093/brain/awae395

N/A

0DataRank · unranked

5 citations

Neel H. Mehta, Evan Dennis, Kedous Y. Mekbib, Benjamin C. Reeves, Emre Kiziltug +15 more

Utility of cortical tissue analysis in normal pressure hydrocephalus

Cerebral Cortex(2024)10.1093/cercor/bhae001

N/A

0DataRank · unranked

8 citations

Kedous Y. Mekbib, Neel H. Mehta, Emre Kiziltug, Phan Q. Duy, Hannah Smith +10 more

Concurrent Chiari malformation type I and hydrocephalus: Integrating mechanistic and pathophysiological insights toward a unified management paradigm

Experimental Neurology(2025)10.1016/j.expneurol.2025.115535

N/A

0DataRank · unranked

2 citations

Neel H. Mehta, Eric M. Jackson, Brandon G. Rocque, Phan Q. Duy, William J Munoz Miranda +5 more

Somatic TEK Mutation Identified in a Patient with Calvarial Venous Malformations

Genes(2025)10.3390/genes16101123

N/A

0DataRank · unranked

0 citations

Evan Dennis, Neel H. Mehta, William Davalan, Carla Fortes, A Narayana Swamy +5 more

Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets

Nature Reviews Neurology(2020)10.1038/s41582-020-0321-y

N/A

0DataRank · unranked

240 citations

Benjamin C. Reeves, Eyiyemisi C. Damisah, Phan Q. Duy, Prince Antwi, Wyatt B. David +9 more

Animal models of Chiari malformation types 1 and 2: Mechanistic insights and translational challenges

Experimental Neurology(2025)10.1016/j.expneurol.2025.115473

N/A

0DataRank · unranked

0 citations

Qiang Li, Andrew T. Hale, Baojian Fan, Phan Q. Duy, Neel H. Mehta +9 more

Exome Sequencing Implicates Impaired GABA Signaling and Neuronal Ion Transport in Trigeminal Neuralgia

iScience(2020)10.1016/j.isci.2020.101552

N/A

0DataRank · unranked

47 citations

Sheng Chih Jin, August Allocco, Xue Zeng, Amar H. Sheth, Shreyas Panchagnula +44 more

Exome Sequencing as a Potential Diagnostic Adjunct in Sporadic Congenital Hydrocephalus

JAMA Pediatrics(2020)10.1001/jamapediatrics.2020.4878

N/A

0DataRank · unranked

15 citations

Benjamin C. Reeves, Phan Q. Duy, Carol Nelson‐Williams, Weilai Dong, Sheng Chih Jin +2 more

Preclinical insights into therapeutic targeting of KCC2 for disorders of neuronal hyperexcitability

Expert Opinion on Therapeutic Targets(2020)10.1080/14728222.2020.1762174

N/A

0DataRank · unranked

14 citations

Miao He, Zhigang He, Kristopher T. Kahle, Phan Q. Duy

Novel EWSR1‐VGLL1 fusion in a pediatric neuroepithelial neoplasm

Clinical Genetics(2020)10.1111/cge.13703

N/A

0DataRank · unranked

8 citations

Benjamin C. Reeves, Carol Nelson‐Williams, Christopher S. Hong, Pallavi P. Gopal, Matija Snuderl +3 more

Unique actions of GABA arising from cytoplasmic chloride microdomains

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.29.178160

N/A

0DataRank · unranked

10 citations

Kieran P. Normoyle, Joseph Glykys, Volodymyr Dzhala, Kyle P. Lillis, Kristopher T. Kahle +4 more