🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Dinesh Thummuri

University of Florida

ORCID: 0000-0002-6027-0999
MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile
0Author DataRank

Indexed papers

0in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 12 papers. Top paper: “Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity”.

Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity

Nature Communications(2020)10.1038/s41467-020-15838-0
N/A
0.838DataRank · unranked
266 citations

Xuan Zhang, Jianhui Chang, Ha‐Neui Kim, Peiyi Zhang, Yingying Wang +17 more

Long-Term Gemcitabine Treatment Reshapes the Pancreatic Tumor Microenvironment and Sensitizes Murine Carcinoma to Combination Immunotherapy

Cancer Research(2020)10.1158/0008-5472.can-19-2959
N/A
0.729DataRank · unranked
128 citations

Matthew Narbutis, Sandeep Kumar, Alex Park, Navin Viswakarma, Matthew J. Dorman +10 more

BCL-XL PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRASG12C-mutated cancers

Journal of Hematology & Oncology(2022)10.1186/s13045-022-01241-3
N/A
0.621DataRank · unranked
62 citations

J Wiegand, Peiyi Zhang, Wanyi Hu, Dinesh Thummuri, Vivekananda Budamagunta +9 more

Discovery of IAP-recruiting BCL-XL PROTACs as potent degraders across multiple cancer cell lines

European Journal of Medicinal Chemistry(2020)10.1016/j.ejmech.2020.112397
N/A
0DataRank · unranked
65 citations

Yonghan He, Peiyi Zhang, Vivekananda Budamagunta, Dongwen Lv, Dinesh Thummuri +6 more

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity,

Nature Communications(2021)10.1038/s41467-021-27210-x
N/A
0DataRank · unranked
149 citations

Pratik Pal, Xingui Liu, Yannan Jia, Dinesh Thummuri, Peiyi Zhang +19 more

Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL–Specific Degrader DT2216

Molecular Cancer Therapeutics(2021)10.1158/1535-7163.mct-21-0474
N/A
0DataRank · unranked
74 citations

Sajid Khan, Patrick W. Underwood, Peiyi Zhang, J Wiegand, Xuan Zhang +13 more

Co-targeting BCL-X L and MCL-1 with DT2216 and AZD8055 synergistically inhibits small-cell lung cancer growth without causing on-target toxicities in mice

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.12.507616
N/A
0DataRank · unranked
0 citations

Patrick Kellish, Nick Connis, Dinesh Thummuri, J Wiegand, Peiyi Zhang +14 more

Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice

Cell Death Discovery(2023)10.1038/s41420-022-01296-8
N/A
0DataRank · unranked
43 citations

Patrick Kellish, Nick Connis, Dinesh Thummuri, J Wiegand, Peiyi Zhang +14 more

Discovery of XZ338, a highly potent BCL-XL degrader

European Journal of Medicinal Chemistry(2025)10.1016/j.ejmech.2025.117624
N/A
0DataRank · unranked
5 citations

Dinesh Thummuri, Wanyi Hu, Xingui Liu, Peiyi Zhang, Shuo Zhou +3 more

Discovery of PZ671, a highly potent and in vivo active CRBN-recruiting Bcl-xL degrader

RSC Medicinal Chemistry(2025)10.1039/d5md00119f
N/A
0DataRank · unranked
3 citations

Dinesh Thummuri, Wanyi Hu, Sajid Khan, Yonghan He, Xuan Zhang +5 more

DT2216—a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas

Journal of Hematology & Oncology(2020)10.1186/s13045-020-00928-9
N/A
0DataRank · unranked
134 citations

Raphael Koch, Vivekananda Budamagunta, Peiyi Zhang, Xuan Zhang, Sajid Khan +11 more

Discovery of PROTAC BCL-XL degraders as potent anticancer agents with low on-target platelet toxicity

European Journal of Medicinal Chemistry(2020)10.1016/j.ejmech.2020.112186
N/A
0DataRank · unranked
115 citations

Dinesh Thummuri, Xingui Liu, Wanyi Hu, Peiyi Zhang, Sajid Khan +4 more