Seth L. Alper

Also affiliated with Beth Israel Deaconess Medical Center, Harvard University, Massachusetts General Hospital, Massachusetts Institute of Technology

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 30 papers. Top paper: “A High-Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury”.

A High-Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury

Cell Reports Medicine(2020)10.1016/j.xcrm.2020.100137

N/A

3.1DataRank · unranked

72 citations

Eriene-Heidi Sidhom, Abhigyan Satyam, Brian T. Chamberlain, Moran Dvela‐Levitt, Michelle Melanson +31 more

The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus

Cell(2023)10.1016/j.cell.2023.01.017

N/A

2.7DataRank · unranked

145 citations

Benjamin C. Reeves, Emre Kiziltug, Phan Q. Duy, Jason K. Karimy, M. Shahid Mansuri +32 more

Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing

Nature Genetics(2013)10.1038/ng.2543

N/A

0.862DataRank · unranked

313 citations

Andreas Gnirke, David B. Jaffe, Veronika Barešová, Nathalie Pochet, Brendan Blumenstiel +43 more

Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets

Nature Reviews Neurology(2020)10.1038/s41582-020-0321-y

N/A

0.823DataRank · unranked

240 citations

Benjamin C. Reeves, Eyiyemisi C. Damisah, Phan Q. Duy, Prince Antwi, Wyatt B. David +9 more

Modulation of brain cation-Cl− cotransport via the SPAK kinase inhibitor ZT-1a

Nature Communications(2020)10.1038/s41467-019-13851-6

N/A

0.716DataRank · unranked

117 citations

Mohammad Iqbal H. Bhuiyan, Ting Zhang, Jason K. Karimy, Zhijuan Wu, Victoria M. Fiesler +19 more

PTEN mutations in autism spectrum disorder and congenital hydrocephalus: developmental pleiotropy and therapeutic targets

Trends in Neurosciences(2021)10.1016/j.tins.2021.08.007

N/A

0.564DataRank · unranked

42 citations

Marina Carlson, Shreyas Panchagnula, Stephanie M. Robert, Phan Q. Duy, Kellen Mermin‐Bunnell +10 more

Haplotype-resolved germline and somatic alterations in renal medullary carcinomas

Genome Medicine(2021)10.1186/s13073-021-00929-4

N/A

0.560DataRank · unranked

12 citations

Hyunji Kim, Yuxiang Zhang, Won Jun Kim, Guillaume Kugener, Jeremiah A. Wala +15 more

FSGS-Causing INF2 Mutation Impairs Cleaved INF2 N-Fragment Functions in Podocytes

Journal of the American Society of Nephrology(2020)10.1681/asn.2019050443

N/A

0.505DataRank · unranked

28 citations

Justin Chun, Chandra Perez-Gill, Paul Yan, Isaac E. Stillman, Henry N. Higgs +4 more

Mutation of key signaling regulators of cerebrovascular development in vein of Galen malformations

Nature Communications(2023)10.1038/s41467-023-43062-z

N/A

0.500DataRank · unranked

27 citations

Kedous Y. Mekbib, Martijn A. van der Ent, Garrett Allington, Andrew Prendergast, Jocelyn E. Chau +61 more

TRIM71 mutations cause a neurodevelopmental syndrome featuring ventriculomegaly and hydrocephalus

Brain(2024)10.1093/brain/awae175

N/A

0.464DataRank · unranked

21 citations

Bettina Jux, Shujuan Zhao, Kedous Y. Mekbib, Evan Dennis, Weilai Dong +25 more

Disrupted uromodulin trafficking is rescued by targeting TMED cargo receptors

Journal of Clinical Investigation(2024)10.1172/jci180347

N/A

0.442DataRank · unranked

18 citations

Matthew Brown, Jason Zavras, Magdalena Riedl Khursigara, Elizabeth Grinkevich, Eriene-Heidi Sidhom +29 more

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.30.180380

N/A

0.396DataRank · unranked

13 citations

Eriene-Heidi Sidhom, Abhigyan Satyam, Moran Dvela‐Levitt, Michelle Melanson, Brian T. Chamberlain +30 more

Differing sensitivities to angiotensin converting enzyme inhibition of kidney disease mediated by APOL1 high-risk variants G1 and G2

Kidney International(2024)10.1016/j.kint.2024.07.026

N/A

0.373DataRank · unranked

11 citations

Sonako Jacas, Olivia Donovan, Diana Pintye, Nicholas Wiley, Zsuzsanna K. Zsengellér +5 more

Magnesium homeostasis in deoxygenated sickle erythrocytes is modulated by endothelin‐1 via Na + /Mg 2+ exchange

The FASEB Journal(2022)10.1096/fj.202201339r

N/A

0.269DataRank · unranked

5 citations

Yaritza Inostroza‐Nieves, Patricia Pulido‐Perez, Pablo López, Jay G. Wohlgemuth, Jeffrey S. Dlott +4 more

Activation of 2‐oxoglutarate receptor 1 (OXGR1) by α‐ketoglutarate (αKG) does not detectably stimulate Pendrin‐mediated anion exchange in Xenopus oocytes

Physiological Reports(2022)10.14814/phy2.15362

N/A

0.104DataRank · unranked

1 citations

Amar J. Majmundar, Alicia Rivera, Jay G. Wohlgemuth, Jeffrey S. Dlott, L. Michael Snyder +3 more

De novo variants disrupt an LDB1 -regulated transcriptional network in congenital ventriculomegaly

Brain(2024)10.1093/brain/awae395

N/A

0DataRank · unranked

5 citations

Neel H. Mehta, Evan Dennis, Kedous Y. Mekbib, Benjamin C. Reeves, Emre Kiziltug +15 more

Role of ecto‐5′‐nucleotidase in bladder function

The FASEB Journal(2024)10.1096/fj.202301393r

N/A

0DataRank · unranked

3 citations

Ali Wu, Lanlan Zhang, Simon C. Robson, Aria F. Olumi, Seth L. Alper +3 more

Design and structural basis of selective 1,4-dihydropyridine inhibitors of the calcium-activated potassium channel K Ca 3.1

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2425494122

N/A

0DataRank · unranked

8 citations

Youngwoo Nam, Joshua A. Nasburg, Alena Ramanishka, Xuan Rui Ng, Zhong Zhuang +12 more

Animal models of Chiari malformation types 1 and 2: Mechanistic insights and translational challenges

Experimental Neurology(2025)10.1016/j.expneurol.2025.115473

N/A

0DataRank · unranked

0 citations

Qiang Li, Andrew T. Hale, Baojian Fan, Phan Q. Duy, Neel H. Mehta +9 more

Exome Sequencing Implicates Impaired GABA Signaling and Neuronal Ion Transport in Trigeminal Neuralgia

iScience(2020)10.1016/j.isci.2020.101552

N/A

0DataRank · unranked

47 citations

Sheng Chih Jin, August Allocco, Xue Zeng, Amar H. Sheth, Shreyas Panchagnula +44 more

Trpv1 and Trpa1 are not essential for Psickle-like activity in red cells of the SAD mouse model of sickle cell disease

Blood Cells Molecules and Diseases(2021)10.1016/j.bcmd.2021.102619

N/A

0DataRank · unranked

1 citations

Alicia Rivera, Boris E. Shmukler, Jay G. Wohlgemuth, Jeffrey S. Dlott, L. Michael Snyder +4 more

Brain ventricles as windows into brain development and disease

Neuron(2022)10.1016/j.neuron.2021.12.009

N/A

0DataRank · unranked

60 citations

Pasko Rakić, Seth L. Alper, William E. Butler, Christopher A. Walsh, Nenad Šestan +4 more

A neural stem cell paradigm of pediatric hydrocephalus

Cerebral Cortex(2022)10.1093/cercor/bhac341

N/A

0DataRank · unranked

31 citations

Pasko Rakić, Seth L. Alper, Stephanie M. Robert, Adam J. Kundishora, William E. Butler +6 more

Dysregulated Erythroid Mg2+ Efflux in Type 2 Diabetes

Frontiers in Cell and Developmental Biology(2022)10.3389/fcell.2022.861644

N/A

0DataRank · unranked

5 citations

Alicia Rivera, Jay G. Wohlgemuth, Jeffrey S. Dlott, L. Michael Snyder, Seth L. Alper +2 more

Multiomic analyses implicate a neurodevelopmental program in the pathogenesis of cerebral arachnoid cysts

Nature Medicine(2023)10.1038/s41591-023-02238-2

N/A

0DataRank · unranked

20 citations

Garrett Allington, Stephen McGee, Kedous Y. Mekbib, Vladimir G. Gainullin, Andrew T. Timberlake +31 more

A novel SMARCC1 BAFopathy implicates neural progenitor epigenetic dysregulation in human hydrocephalus

Brain(2023)10.1093/brain/awad405

N/A

0DataRank · unranked

18 citations

Garrett Allington, Stephen Viviano, Stephen McGee, Emre Kiziltug, Shaojie Ma +25 more

Blockade of the mineralocorticoid receptor improves markers of human endothelial cell dysfunction and hematological indices in a mouse model of sickle cell disease

The FASEB Journal(2023)10.1096/fj.202300671r

N/A

0DataRank · unranked

6 citations

Christopher Vega, Arelys Ramos‐Rivera, Enrique R Maldonado, Gregory N. Prado, Hope E. Karnes +5 more

Genetic dysregulation of an endothelial Ras signaling network in vein of Galen malformations

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.18.532837

N/A

0DataRank · unranked

3 citations

Kedous Y. Mekbib, Martijn A. van der Ent, Garrett Allington, Andrew Prendergast, Jocelyn E. Chau +58 more

A novel SMARCC1 -mutant BAFopathy implicates epigenetic dysregulation of neural progenitors in hydrocephalus

medRxiv(2023)10.1101/2023.03.19.23287455

N/A

0DataRank · unranked

1 citations

Stephen Viviano, Garrett Allington, Stephen McGee, Emre Kiziltug, Kedous Y. Mekbib +24 more

Genetic risk factors for Mesoamerican nephropathy

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2404848121

N/A

0DataRank · unranked

15 citations

Dominick Leone, Juan José Amador, Joseph Kupferman, Lauren J. Francey, Damaris López-Pilarte +25 more