Michael P. Hughes

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 13 papers. Top paper: “The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure”.

The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1917914117

N/A

4.3DataRank · unranked

183 citations

Binsen Li, Chuanqi Sun, Weijia Fan, Kang Zhou, Michael P. Hughes +4 more

CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid

Nature Communications(2020)10.1038/s41467-020-17905-y

N/A

0DataRank · unranked

116 citations

Qin Cao, Michael P. Hughes, M.R. Sawaya, David R. Boyer, Duilio Cascio +2 more

The cryoEM structure of the fibril-forming low-complexity domain of hnRNPA2 reveals distinct differences from pathogenic amyloid and shows how mutation converts it to the pathogenic form

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.24.113621

N/A

0DataRank · unranked

1 citations

Qin Cao, Michael P. Hughes, M.R. Sawaya, David R. Boyer, Duilio Cascio +2 more

The expanding amyloid family: Structure, stability, function, and pathogenesis

Cell(2021)10.1016/j.cell.2021.08.013

N/A

0DataRank · unranked

479 citations

Michael P. Hughes, José A. Rodríguez, Roland Riek, David Eisenberg, M.R. Sawaya

Prevalence and species distribution of the low-complexity, amyloid-like, reversible, kinked segment structural motif in amyloid-like fibrils

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101194

N/A

0DataRank · unranked

47 citations

Lukasz Goldschmidt, David Eisenberg, Michael P. Hughes

A spatiotemporal reconstruction of the C. elegans pharyngeal cuticle reveals a structure rich in phase-separating proteins

eLife(2022)10.7554/elife.79396

N/A

0DataRank · unranked

48 citations

Levon Tokmakjian, Jessica Knox, Peter Mastrangelo, Jingxiu Ji, Hao Cai +10 more

Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies

Nature Structural & Molecular Biology(2022)10.1038/s41594-022-00774-y

N/A

0DataRank · unranked

43 citations

Michael P. Hughes, Carolyn J. Hu, M.R. Sawaya, Łukasz Salwiński, Hope Pan +4 more

Extended β-Strands Contribute to Reversible Amyloid Formation

ACS Nano(2022)10.1021/acsnano.1c08043

N/A

0DataRank · unranked

30 citations

Declan Evans, Michael P. Hughes, M.R. Sawaya, Carolyn J. Hu, K. N. Houk +2 more

Bioinformatic identification of previously unrecognized amyloidogenic proteins

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.101920

N/A

0DataRank · unranked

12 citations

Kevin A. Murray, Łukasz Salwiński, Michael P. Hughes, Romany Abskharon, David Eisenberg +1 more

A Spatiotemporal Reconstruction of the C. elegans Pharyngeal Cuticle Reveals a Structure Rich in Phase-Separating Proteins

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.11.483951

N/A

0DataRank · unranked

0 citations

Levon Tokmakjian, Jessica Knox, Peter Mastrangelo, Jingxiu Ji, Hao Cai +10 more

Cryo-EM structures of the D290V mutant of the hnRNPA2 low-complexity domain suggests how D290V affects phase separation and aggregation

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105531

N/A

0DataRank · unranked

5 citations

P. Ge, M.R. Sawaya, Michael P. Hughes, David R. Boyer, Qin Cao +5 more

Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.29.546885

N/A

0DataRank · unranked

8 citations

Bryan A. Johnson, Victoria Meliopoulos, Xiaohui Ju, Peipei Zhang, Michael P. Hughes +22 more

Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity

Cell Reports(2024)10.1016/j.celrep.2024.113965

N/A

0DataRank · unranked

61 citations

Bryan A. Johnson, Victoria Meliopoulos, Xiaohui Ju, Peipei Zhang, Michael P. Hughes +23 more