Tyler B. Johnson

Also affiliated with Amicus Therapeutics (United States)

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 13 papers. Top paper: “Early postnatal administration of an AAV9 gene therapy is safe and efficacious in CLN3 disease”.

Early postnatal administration of an AAV9 gene therapy is safe and efficacious in CLN3 disease

Frontiers in Genetics(2023)10.3389/fgene.2023.1118649

N/A

0.589DataRank · unranked

20 citations

Jon J. Brudvig, Shibi Likhite, Melissa A. Pratt, Katherine A. White, Jacob T. Cain +10 more

Intracranial delivery of AAV9 gene therapy partially prevents retinal degeneration and visual deficits in CLN6-Batten disease mice

Molecular Therapy — Methods & Clinical Development(2021)10.1016/j.omtm.2020.12.014

N/A

0.449DataRank · unranked

19 citations

Hemanth R. Nelvagal, Timothy A. Poole, Bin Lü, Tyler B. Johnson, Samantha S. Davis +10 more

Transmembrane Batten Disease Proteins Interact With a Shared Network of Vesicle Sorting Proteins, Impacting Their Synaptic Enrichment

Frontiers in Neuroscience(2022)10.3389/fnins.2022.834780

N/A

0.345DataRank · unranked

9 citations

Brandon L. Meyerink, Hannah G. Leppert, Tyler B. Johnson, Jacob T. Cain, Gavin Ferrandino +5 more

AAV9 gene therapy restores lifespan and treats pathological and behavioral abnormalities in a mouse model of CLN8-Batten disease

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.05.079350

N/A

0.104DataRank · unranked

1 citations

Katherine A. White, Jacob T. Cain, Logan M. Langin, Melissa A. Pratt, Jon J. Brudvig +8 more

Transmembrane Batten disease proteins interact with a shared network of vesicle sorting proteins to regulate synaptic composition and function

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.16.460691

N/A

0DataRank · unranked

2 citations

Brandon L. Meyerink, Hannah G. Leppert, Tyler B. Johnson, Jacob T. Cain, Gavin Ferrandino +5 more

Sex-split analysis of pathology and motor-behavioral outcomes in a mouse model of CLN8-Batten disease reveals an increased disease burden and trajectory in female Cln8mnd mice

Orphanet Journal of Rare Diseases(2022)10.1186/s13023-022-02564-7

N/A

0DataRank · unranked

6 citations

Katherine A. White, Melissa A. Pratt, Tyler B. Johnson, Shibi Likhite, Kathrin Meyer +2 more

A novel porcine model of CLN3 Batten disease recapitulates clinical phenotypes

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.07.511360

N/A

0DataRank · unranked

2 citations

Katherine A. White, Tyler B. Johnson, Xiaojun Wang, Jimin Han, David A. Pearce +5 more

A novel porcine model of CLN3 Batten disease recapitulates clinical phenotypes

Disease Models & Mechanisms(2023)10.1242/dmm.050038

N/A

0DataRank · unranked

15 citations

Katherine A. White, Tyler B. Johnson, Xiaojun Wang, Jimin Han, David A. Pearce +7 more

Therapeutic efficacy of antisense oligonucleotides in mouse models of CLN3 Batten disease

Nature Medicine(2020)10.1038/s41591-020-0986-1

N/A

0DataRank · unranked

53 citations

Francine M. Jodelka, Anthony J. Hinrich, Tyler B. Johnson, Joseph Ochaba, Michaela Jackson +5 more

Sortilin inhibition treats multiple neurodegenerative lysosomal storage disorders

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.22.559064

N/A

0DataRank · unranked

4 citations

Joelle T. Anderson, Kaylie J. Timm, C. Davoli, Melissa A. Pratt, Clarissa D. Booth +7 more

A tailored Cln3Q352X mouse model for testing therapeutic interventions in CLN3 Batten disease

Scientific Reports(2020)10.1038/s41598-020-67478-5

N/A

0DataRank · unranked

22 citations

Tyler B. Johnson, Attila Kovács, David A. Pearce, Jill M. Weimer, Logan M. Langin

AAV9 Gene Therapy Increases Lifespan and Treats Pathological and Behavioral Abnormalities in a Mouse Model of CLN8-Batten Disease

Molecular Therapy(2020)10.1016/j.ymthe.2020.09.033

N/A

0DataRank · unranked

43 citations

Katherine A. White, Jon J. Brudvig, Jacob T. Cain, Logan M. Langin, Melissa A. Pratt +8 more

A human model of Batten disease shows role of CLN3 in phagocytosis at the photoreceptor–RPE interface

Communications Biology(2021)10.1038/s42003-021-01682-5

N/A

0DataRank · unranked

39 citations

Jimin Han, Sonal Dalvi, Kannan Vrindavan Manian, Lauren Winschel, Stefanie Volland +16 more