James A. Lederer

Also affiliated with Whitehead Institute for Biomedical Research

Immunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 37 papers. Top paper: “Granzyme K activates the entire complement cascade”.

Granzyme K activates the entire complement cascade

Nature(2025)10.1038/s41586-025-08713-9

N/A

1.5DataRank · unranked

118 citations

Erin Theisen, Fan Zhang, Aparna Nathan, Madison L. Fairfield, Karishma Vijay Rupani +89 more

Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis

Nature Communications(2024)10.1038/s41467-024-52586-x

N/A

1.1DataRank · unranked

18 citations

Tan‐Yun Cheng, Ilya Korsunsky, Gerald F. Watts, Shani T. Gal-Oz, William V. Trim +94 more

Tissue-specific enhancer–gene maps from multimodal single-cell data identify causal disease alleles

Nature Genetics(2024)10.1038/s41588-024-01682-1

N/A

0.972DataRank · unranked

52 citations

Kathryn Weinand, Shakson Isaac, Kushal K. Dey, Karthik A. Jagadeesh, Masahiro Kanai +86 more

Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis

Journal of Clinical Investigation(2025)10.1172/jci185217

N/A

0.717DataRank · unranked

31 citations

Joshua Keegan, Alec Griffith, Tusharkanti Ghosh, Alice Horisberger, Kaitlyn Howard +37 more

Carbon monoxide-induced autophagy enhances human mesenchymal stromal cell function via paracrine actions in murine polymicrobial sepsis

Molecular Therapy(2024)10.1016/j.ymthe.2024.05.018

N/A

0.594DataRank · unranked

15 citations

Sailaja Ghanta, Qifei Li, Anthony M. Lamattina, Ekaterina Murzin, James A. Lederer +5 more

Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.14.575609

N/A

0.477DataRank · unranked

9 citations

Alec Griffith, Joshua Keegan, Arnon Arazi, John Pulford, Ekaterina Murzin +49 more

Robust integration of single-cell cytometry datasets

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.28.450128

N/A

0.267DataRank · unranked

2 citations

Søren Helweg Dam, Mike Bogetofte Barnkob, Michael D. Leipold, Noelia Purroy, Laura Z. Rassenti +7 more

Mechanisms Driving Neutrophil-Induced T-cell Immunoparalysis in Ovarian Cancer

Cancer Immunology Research(2021)10.1158/2326-6066.cir-20-0922

N/A

0DataRank · unranked

74 citations

Thejaswini Giridharan, Kelly L. Singel, A. Nazmul H. Khan, Jason Ricciuti, Kaitlyn Howard +22 more

Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis

JCI Insight(2021)10.1172/jci.insight.149185

N/A

0DataRank · unranked

48 citations

Kacie J. Hoyt, Kevin Wei, María Gutiérrez‐Arcelus, Maria L. Taylor, Julie Ng +20 more

A T cell inflammatory phenotype is associated with autoimmune toxicity of the PI3K inhibitor duvelisib in chronic lymphocytic leukemia

Leukemia(2021)10.1038/s41375-021-01441-9

N/A

0DataRank · unranked

21 citations

Alec Griffith, Svitlana Tyekucheva, Zixu Wang, Vanessa Rai, Alexander R. Vartanov +14 more

miR-378-3p Knockdown Recapitulates Many of the Features of Myelodysplastic Syndromes

American Journal Of Pathology(2021)10.1016/j.ajpath.2021.07.006

N/A

0DataRank · unranked

5 citations

Miao Lin, Begum Utz, Amma Bosompem, Yan Guo, Yahya Daneshbod +12 more

Mesenchymal stromal cells expressing a dominant-negative high mobility group A1 transgene exhibit improved function during sepsis

Journal of Leukocyte Biology(2021)10.1002/jlb.4a0720-424r

N/A

0DataRank · unranked

4 citations

Sailaja Ghanta, Julie Ng, Ana P. Castaño, Junwen Han, Bonna Ith +6 more

Intratracheal transplantation of trophoblast stem cells attenuates acute lung injury in mice

Stem Cell Research & Therapy(2021)10.1186/s13287-021-02550-z

N/A

0DataRank · unranked

2 citations

Li Gu, Minmin Hou, Julie Ng, Min‐Young Kwon, Kevin Xiong +11 more

Aging and interferon gamma response drive the phenotype of neutrophils in the inflamed joint

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.16.465905

N/A

0DataRank · unranked

1 citations

Tarik Exner, Nicolaj Hackert, Felix A. Radtke, Scott A. Jelinsky, Olha Halyabar +13 more

cyCombine allows for robust integration of single-cell cytometry datasets within and across technologies

Nature Communications(2022)10.1038/s41467-022-29383-5

N/A

0DataRank · unranked

127 citations

Søren Helweg Dam, Mike Bogetofte Barnkob, Michael D. Leipold, Noelia Purroy, Laura Z. Rassenti +7 more

Pirtobrutinib targets BTK C481S in ibrutinib-resistant CLL but second-site BTK mutations lead to resistance

Blood Advances(2022)10.1182/bloodadvances.2022008447

N/A

0DataRank · unranked

80 citations

Filippo Utro, Qing Wang, Justin Cha, Mauno Vihinen, Stephen P. Martindale +20 more

High incidence of proliferative and membranous nephritis in SLE patients with low proteinuria in the Accelerating Medicines Partnership

Lara D. Veeken(2022)10.1093/rheumatology/keac067

N/A

0DataRank · unranked

32 citations

Jessica Li, Andrea Fava, Kristina Deonaraine, David Wofsy, Judith A. James +95 more

Idelalisib reduces regulatory T cells and activates T helper 17 cell differentiation in relapsed refractory patients with chronic lymphocytic leukaemia

British Journal of Haematology(2022)10.1111/bjh.18053

N/A

0DataRank · unranked

15 citations

Alec Griffith, Zixu Wang, Svitlana Tyekucheva, Vanessa Rai, Stacey M. Fernandes +5 more

Distinct Injury Responsive Regulatory T Cells Identified by Multi-Dimensional Phenotyping

Frontiers in Immunology(2022)10.3389/fimmu.2022.833100

N/A

0DataRank · unranked

7 citations

Brandon L. Hancock, Alec Griffith, Hui Lin, Kaitlyn Howard, Joshua Keegan +6 more

Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution

Nature Genetics(2023)10.1038/s41588-023-01586-6

N/A

0DataRank · unranked

43 citations

Amber Shen, Saisriram Gurajala, Aparna Nathan, Laurie Rumker, Vitor R. C. Aguiar +95 more

Type I interferon signature and cycling lymphocytes in macrophage activation syndrome

Journal of Clinical Investigation(2023)10.1172/jci165616

N/A

0DataRank · unranked

38 citations

Kailey Brodeur, Liang Chen, Du, Holly Wobma, Evan E. Hsu +25 more

Nasal polyp antibody-secreting cells display proliferation signature in aspirin-exacerbated respiratory disease

Journal of Allergy and Clinical Immunology(2023)10.1016/j.jaci.2023.10.011

N/A

0DataRank · unranked

22 citations

Jonathan Hacker, Tessa Ryan, Alanna McGill, Regan W. Bergmark, Neil Bhattacharyya +9 more

Mesenchymal Stromal Cells Facilitate Neutrophil-Trained Immunity by Reprogramming Hematopoietic Stem Cells

Journal of Innate Immunity(2023)10.1159/000533732

N/A

0DataRank · unranked

16 citations

Anna E. Marneth, Alec Griffith, Daniel Younger, Sailaja Ghanta, Alan Jiao +11 more

Cytomegalovirus durably primes neutrophil oxidative burst

Journal of Leukocyte Biology(2023)10.1093/jleuko/qiad091

N/A

0DataRank · unranked

3 citations

Michael Dombek, Michael Gutknecht, Marion Grießl, Ingred Riça, Barbora Vlková +11 more

High-dimensional immunophenotyping reveals immune cell aberrations in patients with undiagnosed inflammatory and autoimmune diseases

Journal of Clinical Investigation(2023)10.1172/jci169619

N/A

0DataRank · unranked

3 citations

Takanori Sasaki, Joshua Keegan, Jennifer P. Nguyen, Alec Griffith, Alice Horisberger +21 more

Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.03.547507

N/A

0DataRank · unranked

8 citations

Joshua Keegan, Alec Griffith, Tusharkanti Ghosh, Alice Horisberger, Kaitlyn Howard +34 more

Data from Mechanisms Driving Neutrophil-Induced T-cell Immunoparalysis in Ovarian Cancer

(2023)10.1158/2326-6066.c.6550174

N/A

0DataRank · unranked

0 citations

Thejaswini Giridharan, Kelly L. Singel, ANM Nazmul H. Khan, Jason Ricciuti, Kaitlyn Howard +22 more

The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis

Nature Communications(2024)10.1038/s41467-024-48620-7

N/A

0DataRank · unranked

39 citations

Saori Sakaue, Aparna Nathan, A. Helena Jonsson, Fan Zhang, Gerald F. Watts +82 more

Neutrophil Heterogeneity Identifies an Association of LAMP1 With Proliferative Lupus Nephritis

European Journal of Immunology(2025)10.1002/eji.70022

N/A

0DataRank · unranked

1 citations

Panagiotis Garantziotis, Frank Y. Huang, Georg Schett, Accelerating Medicines Partnership: RA/SLE Network, James A. Lederer +4 more

Quick COVID-19 Healers Sustain Anti-SARS-CoV-2 Antibody Production

Cell(2020)10.1016/j.cell.2020.10.051

N/A

0DataRank · unranked

210 citations

Adam Zuiani, Stephanie Fischinger, Jyotsna Mullur, Caroline Atyeo, Meghan Travers +25 more

Therapeutic impact of human trophoblast stem cells in peritoneal and pneumonia-induced sepsis in mice

Stem Cell Research & Therapy(2025)10.1186/s13287-025-04479-z

N/A

0DataRank · unranked

0 citations

Li Gu, Ekaterina Murzin, Cassidy J. Mays, James A. Lederer, Xiaoli Liu +2 more

Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types

Nature Communications(2020)10.1038/s41467-020-17704-5

N/A

0DataRank · unranked

163 citations

Nina Cheng, Joshua Keegan, Ameen Chaudry, Joseph Driver, Wenya Linda Bi +3 more

Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis

JCI Insight(2020)10.1172/jci.insight.132508

N/A

0DataRank · unranked

71 citations

Kacie J. Hoyt, Pui Y. Lee, Deepak A. Rao, A. Helena Jonsson, Jennifer P. Nguyen +23 more

Trauma induces expansion and activation of a memory-like Treg population

Journal of Leukocyte Biology(2020)10.1002/jlb.4a0520-122r

N/A

0DataRank · unranked

16 citations

Goro Tajima, Joshua Keegan, Yasutaka Nakahori, Fei Fei Guo, Anupamaa Seshadri +3 more

Characterization of pulmonary immune responses to hyperoxia by high-dimensional mass cytometry analyses

Scientific Reports(2020)10.1038/s41598-020-61489-y

N/A

0DataRank · unranked

19 citations

Yasutaka Nakahori, Laura A. Cahill, David Gallo, Joshua Keegan, Jennifer P. Nguyen +4 more

Circulating Factors in Trauma Plasma Activate Specific Human Immune Cell Subsets

Injury(2020)10.1016/j.injury.2020.03.009

N/A

0DataRank · unranked

12 citations

Fei Guo, Jennifer P. Nguyen, Fan Zhang, Anupamaa Seshadri, Joshua Keegan +7 more

IL-1β–driven osteoclastogenic Tregs accelerate bone erosion in arthritis

Journal of Clinical Investigation(2021)10.1172/jci141008

N/A

0DataRank · unranked

93 citations

Margaret H. Chang, Julia T. Schnell, Nathan Nelson-Maney, Jing Yan, Marta Martínez‐Bonet +12 more