John J. O’Shea

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Immunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 34 papers. Top paper: “Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus”.

Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus

Nature Communications(2021)10.1038/s41467-021-23361-z

N/A

3.6DataRank · unranked

200 citations

Sarthak Gupta, Michael A. Davis, Elaine Poncio, Yenealem Temesgen‐Oyelakin, Philip M. Carlucci +34 more

Cholesterol 25-hydroxylase is a metabolic switch to constrain T cell–mediated inflammation in the skin

Science Immunology(2021)10.1126/sciimmunol.abb6444

N/A

0.464DataRank · unranked

21 citations

Hiroyuki Nomura, Hisato Iriki, Akiko Kubo, Koichi Isami, Yohei Mikami +15 more

A coding single nucleotide polymorphism in the interleukin-6 receptor enhances IL-6 signalling in CD4 T cells and predicts treatment response to tocilizumab in giant cell arteritis

Annals of the Rheumatic Diseases(2025)10.1016/j.ard.2025.01.049

N/A

0.360DataRank · unranked

10 citations

Christopher Redmond, McKella Sylvester, Mary Maclean, Luciana Yamamoto Almeida, Kaitlin A. Quinn +17 more

Compromised counterselection by FAS creates an aggressive subtype of germinal center lymphoma

The Journal of Experimental Medicine(2020)10.1084/jem.20201173

N/A

0DataRank · unranked

34 citations

Shreya Agarwal, Nikita Kotlov, Olga Plotnikova, Krystle Nomie, Da Wei Huang +12 more

An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome

UNC Libraries(2020)10.17615/7rbn-e697

N/A

0DataRank · unranked

0 citations

Susanne M. Benseler, Raphaela Goldbach‐Mansky, Yin Liu, Kristien J.M. Zaal, Angélique Biancotto +18 more

BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells

Nature Immunology(2021)10.1038/s41590-021-00868-7

N/A

0DataRank · unranked

203 citations

Guohua Lou, Hong‐Wei Sun, Ziang Zhu, Yi Sun, Zeyu Chen +17 more

JAK-STAT signaling in human disease: From genetic syndromes to clinical inhibition

Journal of Allergy and Clinical Immunology(2021)10.1016/j.jaci.2021.08.004

N/A

0DataRank · unranked

116 citations

Madison Alexander, Massimo Gadina, John J. O’Shea, Françoise Meylan, Daniella M. Schwartz +1 more

A Decade of JAK Inhibitors: What Have We Learned and What May Be the Future?

Arthritis & Rheumatology(2021)10.1002/art.41906

N/A

0DataRank · unranked

67 citations

Jacqueline Kieltyka, Roy Fleischmann, Massimo Gadina, John J. O’Shea, Christine Liu

PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory

Cell Reports(2021)10.1016/j.celrep.2021.109804

N/A

0DataRank · unranked

31 citations

Alejandro V. Villarino, Senta M. Kapnick, Silvia Preite, Han‐Yu Shih, Julio Gómez‐Rodríguez +15 more

MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23

Immunity(2021)10.1016/j.immuni.2021.02.015

N/A

0DataRank · unranked

55 citations

Rachael L. Philips, Giuseppe Sciumè, Franziska Petermann, Françoise Meylan, Hiroyuki Nagashima +13 more

MicroRNA-directed pathway discovery elucidates an miR-221/222–mediated regulatory circuit in class switch recombination

The Journal of Experimental Medicine(2021)10.1084/jem.20201422

N/A

0DataRank · unranked

18 citations

Yohei Mikami, Ryan J. McMonigle, Carlos A. Castellanos, Adam K. Wade‐Vallance, Simon K. Zhou +10 more

Multi-Dimensional Gene Regulation in Innate and Adaptive Lymphocytes: A View From Regulomes

Frontiers in Immunology(2021)10.3389/fimmu.2021.655590

N/A

0DataRank · unranked

16 citations

Giuseppe Sciumè, John J. O’Shea, Han‐Yu Shih, Nilisha Fernando

The JAK-STAT pathway at 30: Much learned, much more to do

Cell(2022)10.1016/j.cell.2022.09.023

N/A

0DataRank · unranked

698 citations

Yuxin Wang, HyeonJoo Cheon, Yuka Kanno, Massimo Gadina, Vittorio Sartorelli +5 more

From thymus to tissues and tumors: A review of T-cell biology

Journal of Allergy and Clinical Immunology(2022)10.1016/j.jaci.2022.10.011

N/A

0DataRank · unranked

78 citations

Christopher Redmond, John J. O’Shea, Daniella M. Schwartz, Laura B. Chopp

A central role for STAT5 in the transcriptional programing of T helper cell metabolism

Science Immunology(2022)10.1126/sciimmunol.abl9467

N/A

0DataRank · unranked

54 citations

Arian Laurence, Fred P. Davis, Luis Nivelo, Stephen R. Brooks, Hong‐Wei Sun +7 more

Human germline heterozygous gain-of-function STAT6 variants cause severe allergic disease

The Journal of Experimental Medicine(2023)10.1084/jem.20221755

N/A

0DataRank · unranked

114 citations

Daniel Leung, Mana Momenilandi, Lauren C.W. Jones, Lucia Pacillo, Alyssa James +89 more

Protein kinases: drug targets for immunological disorders

Nature reviews. Immunology(2023)10.1038/s41577-023-00877-7

N/A

0DataRank · unranked

110 citations

Hanna Kim, Massimo Gadina, Pamela L. Schwartzberg, Arian Laurence, John J. O’Shea +1 more

TGF-β uncouples glycolysis and inflammation in macrophages and controls survival during sepsis

Science Signaling(2023)10.1126/scisignal.ade0385

N/A

0DataRank · unranked

91 citations

Chen Yao, Tyrone Dowdy, Wenwen Jin, Yun-Ji Lim, Liliana Catherine Patiño +14 more

Variant STAT4 and Response to Ruxolitinib in an Autoinflammatory Syndrome

New England Journal of Medicine(2023)10.1056/nejmoa2202318

N/A

0DataRank · unranked

79 citations

Sarah A. Blackstone, Gwendolyn Clay, Rachael L. Philips, Brynja Matthiasardottir, Michele Nehrebecky +36 more

Biologic Versus Small Molecule Therapy for Treating Moderate to Severe Atopic Dermatitis: Clinical Considerations

The Journal of Allergy and Clinical Immunology In Practice(2023)10.1016/j.jaip.2023.03.011

N/A

0DataRank · unranked

59 citations

Leslie Castelo‐Soccio, Rishi Seshadri, Eric L. Simpson, John J. O’Shea, Thomas Bieber +2 more

Transcription factor EGR2 controls homing and pathogenicity of TH17 cells in the central nervous system

Nature Immunology(2023)10.1038/s41590-023-01553-7

N/A

0DataRank · unranked

21 citations

Yan Wang, Daniel Chauss, Alejandro V. Villarino, Verena M. Link, Hiroyuki Nagashima +16 more

Transcription factor TCF-1 regulates the functions, but not the development, of lymphoid tissue inducer subsets in different tissues

Cell Reports(2023)10.1016/j.celrep.2023.112924

N/A

0DataRank · unranked

11 citations

Chen Yao, Gang Ren, Kairui Mao, Hyunwoo Chung, Xi Chen +14 more

T cell intrinsic STAT1 signaling prevents aberrant Th1 responses during acute toxoplasmosis

Frontiers in Immunology(2023)10.3389/fimmu.2023.1212190

N/A

0DataRank · unranked

5 citations

David Kugler, Luis Nivelo, Nicolas Vitari, Laura P. Doyle, Svetlana Ristin +5 more

Remodeling of Il4-Il13-Il5 locus underlies selective gene expression

Nature Immunology(2024)10.1038/s41590-024-02007-4

N/A

0DataRank · unranked

15 citations

Justin Shayne, Kan Jiang, Franziska Petermann, Aleksandra Pękowska, Yuka Kanno +2 more

Doxorubicin resistance involves modulation of interferon signaling, transcriptional bursting, and gene co-expression patterns of U-ISGF3-related genes

Neoplasia(2024)10.1016/j.neo.2024.101071

N/A

0DataRank · unranked

6 citations

Seolkyoung Jung, Yuka Kanno, John J. O’Shea, Carson C. Chow, Paweł Trzaskoma

STAT5B leukemic mutations, altering SH2 tyrosine 665, have opposing impacts on immune gene programs

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.20.629685

N/A

0DataRank · unranked

3 citations

Jichun Chen, Rachael L. Philips, Sung‐Gwon Lee, Xingmin Feng, Zhijie Wu +12 more

A dual role of Cohesin in DNA DSB repair

Nature Communications(2025)10.1038/s41467-025-56086-4

N/A

0DataRank · unranked

16 citations

Yafang Shang, Seolkyoung Jung, Kevin Fedkenheuer, Solji Park, Davide Mazza +17 more

STAT5B leukemic mutations, altering SH2 tyrosine 665, have opposing impacts on immune gene programs

Life Science Alliance(2025)10.26508/lsa.202503222

N/A

0DataRank · unranked

5 citations

Jichun Chen, Rachael L. Philips, Sung‐Gwon Lee, Xingmin Feng, Zhijie Wu +14 more

An activating Stat1 mutant disrupts normal STAT4 innate lymphocyte programs during viral infection

Science Immunology(2025)10.1126/sciimmunol.ado5986

N/A

0DataRank · unranked

2 citations

Yi-Chu Liao, Colleen M. Lau, Tasha Morrison, Kan Jiang, Amal Hutchinson +10 more

Paxbp1 restrains cytotoxic and innate cell programs in CD4+ T cells to promote Th2 differentiation

Research Square(2025)10.21203/rs.3.rs-7199764/v1

N/A

0DataRank · unranked

0 citations

Yuki Morimoto, Hiroyuki Nagashima, Stephen R. Brooks, Ijeoma C. Meremikwu, M. Elizabeth Hammond +8 more

SnapShot: Jak-STAT Signaling II

Cell(2020)10.1016/j.cell.2020.04.052

N/A

0DataRank · unranked

87 citations

Massimo Gadina, John J. O’Shea, Yuka Kanno, Alejandro V. Villarino

A PI3Kd-Foxo1-FasL signaling amplification loop rewires CD4+ T helper cell signaling, differentiation and epigenetic remodeling 4854

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.2464

N/A

0DataRank · unranked

0 citations

Pedro Henrique Gazzinelli-Guimarães, Daniel Chauss, Hiroyuki Nagashima, Yu Kang, Tom Hill +14 more

Rapid Enhancer Remodeling and Transcription Factor Repurposing Enable High Magnitude Gene Induction upon Acute Activation of NK Cells

Immunity(2020)10.1016/j.immuni.2020.09.008

N/A

0DataRank · unranked

67 citations

Yohei Mikami, Dragana Janković, Hiroyuki Nagashima, Alejandro V. Villarino, Tasha Morrison +14 more

Divergent Role for STAT5 in the Adaptive Responses of Natural Killer Cells

Cell Reports(2020)10.1016/j.celrep.2020.108498

N/A

0DataRank · unranked

59 citations

Simon Grassmann, Colleen M. Lau, Moritz Rapp, Alejandro V. Villarino, Christin Friedrich +4 more