Patricia L. Opresko

Also affiliated with UPMC Hillman Cancer Center

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 25 papers. Top paper: “Mechanisms of telomerase inhibition by oxidized and therapeutic dNTPs”.

Mechanisms of telomerase inhibition by oxidized and therapeutic dNTPs

Nature Communications(2020)10.1038/s41467-020-19115-y

N/A

0DataRank · unranked

58 citations

Griffin A. Welfer, Bret Freudenthal, Patricia L. Opresko, Samantha L. Sanford

Mechanisms of nucleotide selection by telomerase

eLife(2020)10.7554/elife.55438

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0DataRank · unranked

24 citations

Samantha L. Sanford, Griffin A. Welfer, Samuel A. Johnson, Thu H. Khoang, Patricia L. Opresko +2 more

Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops

UNC Libraries(2020)10.17615/yw1q-8j33

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0DataRank · unranked

0 citations

Patricia L. Opresko, Hidetoshi Tahara, Vilhelm A. Bohr, Rika Kusumoto‐Matsuo, Dale A. Ramsden

TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA

Nucleic Acids Research(2021)10.1093/nar/gkab1142

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0DataRank · unranked

15 citations

Ryan Barnes, Hai Pan, Ariana C. Detwiler, Ming Liu, Chelsea Mahn +9 more

Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNA

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101080

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0DataRank · unranked

9 citations

Parminder Kaur, Ryan Barnes, Ariana C. Detwiler, Samantha L. Sanford, Ming Liu +15 more

Telomeric 8-Oxoguanine Drives Rapid Premature Senescence In The Absence Of Telomere Shortening

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.05.442662

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0DataRank · unranked

10 citations

Mariarosaria De Rosa, Sanjana A. Thosar, Ariana C. Detwiler, Vera Roginskaya, Bennett Van Houten +4 more

Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening

Nature Structural & Molecular Biology(2022)10.1038/s41594-022-00790-y

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0DataRank · unranked

116 citations

Mariarosaria De Rosa, Sanjana A. Thosar, Ariana C. Detwiler, Vera Roginskaya, Bennett Van Houten +4 more

Global and transcription-coupled repair of 8-oxoG is initiated by nucleotide excision repair proteins

Nature Communications(2022)10.1038/s41467-022-28642-9

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0DataRank · unranked

82 citations

Arjan F. Theil, Vera Roginskaya, Yasmin Ali, Michael Calderon, Simon C. Watkins +7 more

UV light-induced dual promoter mutations dismantle the telomeric guardrails in melanoma

DNA repair(2022)10.1016/j.dnarep.2022.103446

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0DataRank · unranked

1 citations

Patricia L. Opresko, Samantha L. Sanford

Nanofluidic Device for Manipulation and Modification of DNA by Proteins

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.29.521498

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0DataRank · unranked

1 citations

Ming Liu, Zubair Azad, Preston Countryman, Maedeh Roushan, Gideon I. Livshits +9 more

BG4 antibody can recognize telomeric G-quadruplexes harboring destabilizing base modifications and lesions

Nucleic Acids Research(2023)10.1093/nar/gkad1209

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0DataRank · unranked

19 citations

Tapas Paul, Samantha L. Sanford, Brittani L Schnable, Ariana C. Detwiler, Sanjana A. Thosar +4 more

Telomere Fragility and MiDAS: Managing the Gaps at the End of the Road

Genes(2023)10.3390/genes14020348

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0DataRank · unranked

13 citations

Sanjana A. Thosar, Patricia L. Opresko, Ryan Barnes

Assembly path dependence of telomeric DNA compaction by TRF1, TIN2, and SA1

Biophysical Journal(2023)10.1016/j.bpj.2023.04.014

N/A

0DataRank · unranked

4 citations

Hai Pan, Parminder Kaur, L Wang, Miao Jin, Ariana C. Detwiler +5 more

OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced cellular senescence

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.10.536247

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0DataRank · unranked

9 citations

Ryan Barnes, Prasanth R. Nyalapatla, Peter Wipf, Patricia L. Opresko, Mariarosaria De Rosa

Co-regulator activity of Mediator of DNA Damage Checkpoint 1 (MDC1) is associated with DNA repair dysfunction and PARP inhibitor sensitivity in lobular carcinoma of the breast

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.29.564555

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0DataRank · unranked

3 citations

Madeleine T. Shackleford, Camryn S. Nesiba, Amanda L. Richer, Zoë Fleischmann, Jordan M. Swartz +11 more

Oxidative guanine base damage plays a dual role in regulating productive ALT-associated homology-directed repair

Cell Reports(2024)10.1016/j.celrep.2023.113656

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0DataRank · unranked

26 citations

Ryan Barnes, Ariana C. Detwiler, Ragini Bhargava, Anne R. Wondisford, Roderick J. O’Sullivan +2 more

Deregulated DNA ADP-ribosylation impairs telomere replication

Nature Structural & Molecular Biology(2024)10.1038/s41594-024-01279-6

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0DataRank · unranked

24 citations

Junyeop Lee, Robert Lu, M. Schuller, Joséphine Groslambert, Ragini Bhargava +8 more

The molecular mechanism for TERRA recruitment and annealing to telomeres

Nucleic Acids Research(2024)10.1093/nar/gkae732

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0DataRank · unranked

8 citations

Wen Ma, Tapas Paul, Ting‐Wei Liao, Chun‐Ying Lee, Samantha L. Sanford +3 more

A persistent variant telomere sequence in a human pedigree

Nature Communications(2024)10.1038/s41467-024-49072-9

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0DataRank · unranked

7 citations

Samantha L. Sanford, Kelly E. Loughridge, Rachel M. Sutton, Anishka H. Parikh, Agustin A. Gil Silva +7 more

Oxidative-stress-induced telomere instability drives T cell dysfunction in cancer

Immunity(2025)10.1016/j.immuni.2025.08.008

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0DataRank · unranked

22 citations

Sanjana Thosar, Kevin Quann, William Gunn, Victoria Dean, Bingxian Xie +9 more

OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced senescence in human fibroblasts

Nature Communications(2025)10.1038/s41467-024-55638-4

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0DataRank · unranked

14 citations

Ryan Barnes, Ariana C. Detwiler, Prasanth R. Nyalapatla, Peter Wipf, Patricia L. Opresko +1 more

Comprehensive RAD51C ovarian cancer variant analysis uncouples homologous recombination and replicative functions

Nature Communications(2025)10.1038/s41467-025-61283-2

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0DataRank · unranked

7 citations

Yashpal Rawal, Anna L Palovcak-Lightbourn, Gayatri S. Ganesan, Phoebe S. Parker, Reagan A Russell +15 more

Therapeutic 6-thio-deoxyguanosine inhibits telomere elongation in cancer cells by inducing a non-productive stalled telomerase complex

Nature Communications(2025)10.1038/s41467-025-66534-w

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0DataRank · unranked

4 citations

Mareike Badstübner, Michael H. Gerber, William Mannherz, Noah Lampl, Rachel L. Dannenberg +9 more

Chemotherapeutic 6-thio-2’-deoxyguanosine selectively targets and inhibits telomerase by inducing a non-productive telomere-bound telomerase complex

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.02.05.636339

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0DataRank · unranked

1 citations

Mareike Badstübner, Michael H. Gerber, William Mannherz, Noah Lampl, Rachel L. Dannenberg +9 more

Human ribomes reveal DNA-embedded ribonucleotides as a new type of epigenetic mark

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.27.661996

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0DataRank · unranked

1 citations

Taehwan Yang, Tejasvi Channagiri, Penghao Xu, Y Lee, Mo Sun +20 more