Kuo‐Hsiung Lee

University of North Carolina at Chapel Hill

Biochemistry, Genetics and Molecular BiologyChemistry

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 60 papers. Top paper: “Biologically active isoquinoline alkaloids covering 2014–2018”.

Biologically active isoquinoline alkaloids covering 2014–2018

Medicinal Research Reviews(2020)10.1002/med.21703

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215 citations

Cheng‐Jie Yang, Susan L. Morris‐Natschke, Juncai Li, Xiaodan Yin, Ying‐Qian Liu +6 more

Design, synthesis and structure-activity relationships of 4-phenyl-1H-1,2,3-triazole phenylalanine derivatives as novel HIV-1 capsid inhibitors with promising antiviral activities

European Journal of Medicinal Chemistry(2020)10.1016/j.ejmech.2020.112085

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111 citations

Tianguang Huang, Alexej Dick, Megan E. Meuser, Waleed A. Zalloum, Chin‐Ho Chen +7 more

Nanocarrier-mediated immunogenic chemotherapy for triple negative breast cancer

Journal of Controlled Release(2020)10.1016/j.jconrel.2020.04.040

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57 citations

Nasha Qiu, Limei Shen, Qi Liu, Jing Zhang, Yung‐Yi Cheng +3 more

Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00015

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57 citations

Alexej Dick, Megan E. Meuser, Tianguang Huang, Waleed A. Zalloum, Chin‐Ho Chen +12 more

Design and Synthesis of Quinolizidine Derivatives as Influenza Virus and HIV-1 Inhibitors

Current Medicinal Chemistry(2020)10.2174/0929867328666201229121802

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5 citations

Lei Zhu, Lan Xie, Kuo‐Hsiung Lee, Faisal Malik, Zhijun Li +3 more

Synthesis and in vitro anticancer activities of biotinylated derivatives of glaucocalyxin A and oridonin

Journal of Asian Natural Products Research(2020)10.1080/10286020.2020.1760851

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4 citations

Jinglei Chen, Xianlun Li, Lei Zhao, Yadong Cui, Jiangyun Liu +7 more

Cytotoxic Polyisoprenyl Benzophenonoids from Garcinia subelliptica

UNC Libraries(2020)10.17615/zj5c-5n71

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3 citations

Jing‐Jy Cheng, Chun‐Tang Chiou, Yao‐Haur Kuo, Kenneth F. Bastow, Li‐Ming Yang Kuo +4 more

Cardiac Glycosides from Antiaris toxicaria with Potent Cardiotonic Activity

INDIGO (University of Illinois at Chicago)(2020)10.17615/ww5w-p077

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7 citations

Li-Shian Shi, Ming‐Jai Su, An‐Sheng Lee, Kuo‐Hsiung Lee, Tian‐Shung Wu +5 more

(−)-Neocaryachine, an Antiproliferative Pavine Alkaloid from Cryptocarya laevigata , Induces DNA Double-Strand Breaks

INDIGO (University of Illinois at Chicago)(2020)10.17615/q9er-ps90

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4 citations

Yuki Suzuki, David Newman, Barry R. O’Keefe, Yohei Saito, Kyoko Nakagawa‐Goto +2 more

Development and Preclinical Studies of Broad-Spectrum Anti-HIV Agent (3′ R ,4′ R )-3-Cyanomethyl-4-methyl-3′,4′-di- O -( S )-camphanoyl-(+)- cis -khellactone (3-Cyanomethyl-4-methyl-DCK)

Lanzhou University Institutional Repository(2020)10.17615/decq-t946

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4 citations

Gang Wu, Shibo Jiang, Xiaomei Zhuang, Ruan Jin-xiu, Kuo‐Hsiung Lee +7 more

Acetophenone Monomers from Acronychia trifoliolata

INDIGO (University of Illinois at Chicago)(2020)10.17615/9ph9-3674

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1 citations

Susan L. Morris‐Natschke, Airi Suzuki, David Newman, Kyoko Nakagawa‐Goto, Kuo‐Hsiung Lee +4 more

Metformin Uniquely Prevents Thrombosis by Inhibiting Platelet Activation and mtDNA Release

UNC Libraries(2020)10.17615/hcqf-9g18

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6 citations

Jun Gu, Kuo‐Hsiung Lee, Jwu‐Lai Yeh, Limei Ma, Zhihua Xing +15 more

Plant-derived triterpenoids and analogues as antitumor and anti-HIV agents

UNC Libraries(2020)10.17615/mqh7-kr20

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4 citations

Kuo‐Hsiung Lee, Reen‐Yen Kuo, Susan L. Morris‐Natschke, Keduo Qian

Isolation, Structure Determination, and Anti-HIV Evaluation of Tigliane-Type Diterpenes and Biflavonoid from Stellera chamaejasme

Figshare(2020)10.17615/st11-bb38

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3 citations

Takashi Watanabe, Susan L. Morris‐Natschke, Keduo Qian, Aya Sukemori, Yan Lu +10 more

Antitumor Agents. 272. Structure−Activity Relationships and In Vivo Selective Anti-Breast Cancer Activity of Novel Neo-tanshinlactone Analogues

INDIGO (University of Illinois at Chicago)(2020)10.17615/qstx-dr22

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3 citations

Mien‐Chie Hung, Chieh-Yu Peng, Yizhou Dong, Che‐Ming Teng, Donglei Yu +13 more

Bioactive Constituents from the Roots of Panax japonicus var. major and Development of a LC-MS/MS Method for Distinguishing between Natural and Artifactual Compounds

Figshare(2020)10.17615/qcyb-m460

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3 citations

Tian‐Shung Wu, Keduo Qian, Hsiu‐Hui Chan, Ding-Tzai Li, Kuo‐Hsiung Lee +3 more

Optimization of 4-( N -Cycloamino)phenylquinazolines as a Novel Class of Tubulin-Polymerization Inhibitors Targeting the Colchicine Site

Figshare(2020)10.17615/6211-vz21

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2 citations

Keduo Qian, Xiaofeng Wang, Kuo‐Hsiung Lee, Sheng-Biao Wang, Dongqing Zhu +11 more

Diarylaniline Derivatives as a Distinct Class of HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors

INDIGO (University of Illinois at Chicago)(2020)10.17615/sswy-yd30

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2 citations

Keduo Qian, Li Huang, Lan Xie, Rong Huang, Xingkai Jiang +7 more

Cytotoxic Phenanthrenequinones and 9,10-Dihydrophenanthrenes from Calanthe arisanensis

UNC Libraries(2020)10.17615/0zt3-6g28

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2 citations

Susan L. Morris‐Natschke, Fang‐Rong Chang, Kuo‐Hsiung Lee, Donglei Yu, Chia-Lin Lee +4 more

Design and Synthesis of 2-(3-Benzo[ b ]thienyl)-6,7-methylenedioxyquinolin-4-one Analogues as Potent Antitumor Agents that Inhibit Tubulin Assembly

UNC Libraries(2020)10.17615/gcyb-rb98

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1 citations

Susan L. Morris‐Natschke, Ernest Hamel, Yu‐Hsun Chang, Kuo‐Hsiung Lee, Li‐Jiau Huang +4 more

Design, Synthesis, and Evaluation of Diarylpyridines and Diarylanilines as Potent Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors

Figshare(2020)10.17615/41w3-hj26

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1 citations

Shibo Jiang, Bingjie Qin, Xiao‐Feng Wang, Kuo‐Hsiung Lee, Chin Ho Chen +5 more

Songaricalarins A–E, Cytotoxic Oplopane Sesquiterpenes from Ligularia songarica

INDIGO (University of Illinois at Chicago)(2020)10.17615/r1xn-4z45

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1 citations

Kenneth F. Bastow, Susan L. Morris‐Natschke, Kuo‐Hsiung Lee, Daofeng Chen, Qi Wang +1 more

Total Synthesis and in Vitro Anti-Tumor-Promoting Activities of Racemic Acetophenone Monomers from Acronychia trifoliolata

INDIGO (University of Illinois at Chicago)(2020)10.17615/52kt-ge81

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1 citations

Nobutaka Suzuki, Kyoko Nakagawa‐Goto, Yohei Saito, Kuo‐Hsiung Lee, Harukuni Tokuda +4 more

Antitumor Agents 286. Design, Synthesis, and Structure−Activity Relationships of 3′ R ,4′ R -Disubstituted-2′,2′-dimethyldihydropyrano[2,3- f ]chromone (DSP) Analogues as Potent Chemosensitizers to Overcome Multidrug Resistance

Figshare(2020)10.17615/4q0f-jq40

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1 citations

Kenneth F. Bastow, Kuo‐Hsiung Lee, Ting Zhou, Qian Shi

Design, Synthesis, Mechanisms of Action, and Toxicity of Novel 20( S )-Sulfonylamidine Derivatives of Camptothecin as Potent Antitumor Agents

Figshare(2020)10.17615/t6sq-2e58

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1 citations

Shiow‐Lin Pan, Meijuan Wang, Chih-Ya Wang, Yong‐Long Zhao, Xiaoming Yang +16 more

Antitumor Agents. 280. Multidrug Resistance-Selective Desmosdumotin B Analogues

UNC Libraries(2020)10.17615/jpfg-1z70

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0 citations

Kenneth F. Bastow, Kyoko Nakagawa‐Goto, Hsin‐Yi Hung, Alexander Sedykh, Chin-Yu Lai +5 more

Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitor Agents: Optimization of Diarylanilines with High Potency against Wild-Type and Rilpivirine-Resistant E138K Mutant Virus

(2020)10.17615/50ct-kq06

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0 citations

Na Liu, Bingjie Qin, F. Richard Yu, Kuo‐Hsiung Lee, Wei, Lei +7 more

Synthesis, biological evaluation, and physicochemical property assessment of 4-substituted 2-phenylaminoquinazolines as Mer tyrosine kinase inhibitors

UNC Libraries(2020)10.17615/qxb8-q878

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0 citations

Sheng-Biao Wang, Linna Li, Dexuan Yang, Emika Ohkoshi, Lan Xie +6 more

Total synthesis of plagiochin G and derivatives as potential cancer chemopreventive agents

UNC Libraries(2020)10.17615/fx27-fx23

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0 citations

Yu Zhao, Hong‐Xiang Lou, Susan L. Morris‐Natschke, Rui-Juan Li, Xiaoming Yang +4 more

Development of a Novel Class of Tubulin Inhibitor from Desmosdumotin B with a Hydroxylated Bicyclic B-Ring

UNC Libraries(2020)10.17615/0rre-bf18

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0 citations

Emika Ohkoshi, Kuo‐Hsiung Lee, Masuo Goto, Akifumi Oda, Kyoko Nakagawa‐Goto +1 more

Prodrug design, synthesis and pharmacokinetic evaluation of (3′R, 4′R)-3-hydroxymethyl-4-methyl-3′, 4′-di-O-(S)-camphanoyl-(+)-cis-khellactone

UNC Libraries(2020)10.17615/v96z-zv06

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0 citations

Xiaomei Zhuang, Keduo Qian, Lan Xie, Huanfang Guo, Kuo‐Hsiung Lee +3 more

Camphoratins A−J, Potent Cytotoxic and Anti-inflammatory Triterpenoids from the Fruiting Body of Taiwanofungus camphoratus

UNC Libraries(2020)10.17615/4sac-we97

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0 citations

De-Yang Shen, Chou-Hsiung Chen, Kuo‐Hsiung Lee, Keduo Qian, Yuh‐Chiang Shen +8 more

A Target-Based High Throughput Screen Yields Trypanosoma brucei Hexokinase Small Molecule Inhibitors with Antiparasitic Activity

UNC Libraries(2020)10.17615/1me1-w560

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0 citations

Heidi Dodson, John S. Lazo, James C. Morris, Kuo‐Hsiung Lee, Yoshiki Kashiwada +6 more

Recent Progress on C-4-Modified Podophyllotoxin Analogs as Potent Antitumor Agents: C-4-MODIFIED PODOPHYLLOTOXIN ANALOGS

UNC Libraries(2020)10.17615/99q8-q832

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0 citations

Ying‐Qian Liu, Xuan Tian, Xiao-Bo Zhao, Kuo‐Hsiung Lee, Tian Jing +4 more

Phenanthrene-Based Tylophorine-1 (PBT-1) Inhibits Lung Cancer Cell Growth through the Akt and NF-κB Pathways

UNC Libraries(2020)10.17615/whe7-rz95

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0 citations

Qian Shi, Pan‐Chyr Yang, Kuo‐Hsiung Lee, Linyi Wei, Sung‐Liang Yu +4 more

Triethylated chromones with substituted naphthalenes as tubulin inhibitors

UNC Libraries(2020)10.17615/93h2-tb06

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0 citations

Yukako Taniguchi, Ernest Hamel, Masuo Goto, Kyoko Nakagawa‐Goto, Akifumi Oda +3 more

Toward synthesis of third-generation spin-labeled podophyllotoxin derivatives using isocyanide multicomponent reactions

UNC Libraries(2020)10.17615/e3v1-dn16

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0 citations

Nan Xiang, Liting Wang, Meijuan Wang, Liang Kou, Susan L. Morris‐Natschke +4 more

Novel sesquiterpene lactone analogues as potent anti-breast cancer agents

UNC Libraries(2020)10.17615/aekz-gf52

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0 citations

Jo‐Yu Chen, Munehisa Takeya, Lie‐Fen Shyur, Kyoko Nakagawa‐Goto, Yu-Ting Cheng +3 more

Antitumor Agents. 289. Design, Synthesis, and Anti-Breast Cancer Activity in Vivo of 4-Amino-2 H -benzo[ h ]chromen-2-one and 4-Amino-7,8,9,10-tetrahydro-2 H -benzo[ h ]chromen-2-one Analogues with Improved Water Solubility

UNC Libraries(2020)10.17615/pdyv-mk18

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0 citations

Yizhou Dong, Kyoko Nakagawa‐Goto, Eva Y.-H.P. Lee, Susan L. Morris‐Natschke, Kenneth F. Bastow +3 more

Antitumor Agents. 284. New Desmosdumotin B Analogues with Bicyclic B-Ring as Cytotoxic and Antitubulin Agents

Figshare(2020)10.17615/95ba-nx37

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0 citations

Masuo Goto, Kyoko Nakagawa‐Goto, Emika Ohkoshi, Kuo‐Hsiung Lee, Takashi Kozaka +6 more

Cytotoxic geranylflavonoids from Bonannia graeca

UNC Libraries(2020)10.17615/gnex-w655

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0 citations

Kenneth F. Bastow, Antonella Maggio, Kuo‐Hsiung Lee, Chin-Yu Lai, Sergio Rosselli +3 more

Design, synthesis and experimental validation of novel potential chemopreventive agents using random forest and support vector machine binary classifiers

UNC Libraries(2020)10.17615/pwcn-qk42

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0 citations

Hao Zhu, Liying Zhang, Kuo‐Hsiung Lee, Harukuni Tokuda, Marlene T. Kim +4 more

Dual-Functional abeo -Taxane Derivatives Destabilizing Microtubule Equilibrium and Inhibiting NF-κB Activation

INDIGO (University of Illinois at Chicago)(2020)10.17615/jmc4-ge14

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0 citations

Jia Su, Yu Zhao, Qin‐Shi Zhao, Zhu‐Jun Yao, Susan L. Morris‐Natschke +3 more

Discovery and Development of Natural Product-Derived Chemotherapeutic Agents Based on a Medicinal Chemistry Approach ⊥ †

UNC Libraries(2020)10.17615/zmt4-7y15

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0 citations

Kuo‐Hsiung Lee

Antitumor Agents. 266. Design, Synthesis, and Biological Evaluation of Novel 2-(Furan-2-yl)naphthalen-1-ol Derivatives as Potent and Selective Antibreast Cancer Agents

INDIGO (University of Illinois at Chicago)(2020)10.17615/yegj-5113

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0 citations

Qian Shi, Xiang Wang, Yizhou Dong, Kuo‐Hsiung Lee, Yinan Liu +1 more

Synthesis of novel spin-labeled derivatives of 5-FU as potential antineoplastic agents

UNC Libraries(2020)10.17615/kc31-eq38

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0 citations

Xuan Tian, Susan L. Morris‐Natschke, Yang Liu, Zhijun Zhang, Chih-Ya Wang +6 more

Antitumor Agents 259. Design, Syntheses, and Structure−Activity Relationship Study of Desmosdumotin C Analogs

Figshare(2020)10.17615/rgyx-wf60

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0 citations

Kyoko Nakagawa‐Goto, Wu Jiuhong, Kenneth F. Bastow, Tzu-Hsuan Chen, Kuo‐Hsiung Lee +1 more

Altaicalarins A−D, Cytotoxic Bisabolane Sesquiterpenes from Ligularia altaica

Figshare(2020)10.17615/h005-mg41

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0 citations

Kenneth F. Bastow, Qi Wang, Tzu-Hsuan Chen, Kuo‐Hsiung Lee, Daofeng Chen

Synthesis of novel spin-labeled podophyllotoxin derivatives as potential antineoplastic agents: Part XXV

UNC Libraries(2020)10.17615/a8qs-8h73

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0 citations

Zhijun Zhang, Meijuan Wang, Yang Liu, Ying‐Qian Liu, Nan Xiang +3 more

Picomolar Dichotomous Activity of Gnidimacrin Against HIV-1

UNC Libraries(2020)10.17615/gv8y-2n69

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0 citations

Phong Ho, Kuo‐Hsiung Lee, Li Huang, Chin‐Ho Chen, Jie Yu +1 more

N-Aryl-6-methoxy-1,2,3,4-tetrahydroquinolines: A novel class of antitumor agents targeting the colchicine site on tubulin

UNC Libraries(2020)10.17615/xzv2-mc56

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0 citations

Keduo Qian, Lan Xie, Susan L. Morris‐Natschke, Kuo‐Hsiung Lee, Sheng-Biao Wang +4 more

Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines

UNC Libraries(2020)10.17615/bcc5-n195

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0 citations

Ling‐Chu Chang, Yu Zhao, M. Tsai, Li-Chen Chou, Tian‐Shung Wu +10 more

Ochrocephalamine A, a new quinolizidine alkaloid from Oxytropis ochrocephala Bunge

UNC Libraries(2020)10.17615/xemn-w345

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0 citations

Lijun Li, Cheng‐Jian Tan, Lina Liu, Yu Zhao, Baoyu Zhao +4 more

Design, synthesis, and structure activity relationship analysis of new betulinic acid derivatives as potent HIV inhibitors

European Journal of Medicinal Chemistry(2021)10.1016/j.ejmech.2021.113287

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33 citations

Chin‐Ho Chen, Susan L. Morris‐Natschke, Kuo‐Hsiung Lee, Yu Zhao

New phorbol ester derivatives as potent anti-HIV agents

Bioorganic & Medicinal Chemistry Letters(2021)10.1016/j.bmcl.2021.128319

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8 citations

Yung‐Yi Cheng, Lei Zhao, Xiaolei Huang, Xiaogang Jiang, Yadong Cui +7 more

Eleven new C19-diterpenoid alkaloids from Delphinium elatum cv. Pacific Giant

Journal of Natural Medicines(2021)10.1007/s11418-021-01569-z

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4 citations

Nozomi Doi, Nana Hanawa, Manami Itoh, Wataru Nakano, Eri Takahashi +7 more

Antitumor agents 294. Novel E-ring-modified camptothecin–4β-anilino-4′-O-demethyl-epipodophyllotoxin conjugates as DNA topoisomerase I inhibitors and cytotoxic agents

UNC Libraries(2021)10.17615/js69-fg44

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1 citations

Seung‐Whan Kim, Hao Zhu, Qian Shi, Chung‐Hang Leung, Shin‐Young Park +6 more

Biology of quinoline and quinazoline alkaloids

The Alkaloids. Chemistry and biology/The alkaloids. Chemistry and biology(2022)10.1016/bs.alkal.2021.08.002

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21 citations

Susan L. Morris‐Natschke, Ying‐Qian Liu, Xiuhui Li, Jiyu Zhang, Kuo‐Hsiung Lee +1 more

Antiproliferative Effect of N-Heterocyclo-Coumarin Derivatives against Multidrug-Resistant Cells

Chemical and Pharmaceutical Bulletin(2022)10.1248/cpb.c22-00585

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7 citations

Masuo Goto, Kuo‐Hsiung Lee, Hiroshi Yamashita, Koji Wada

Palladium (II), platinum (II) and silver (I) complexes with oxazolines: Their synthesis, characterization, DFT calculation, molecular docking and antitumour effects

Journal of Inorganic Biochemistry(2022)10.1016/j.jinorgbio.2022.112048

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5 citations

Jingcheng Zhang, Hao Yin, Chengming Wang, Lan Xie, Kang-Po Li +7 more