John K. Lee

Also affiliated with Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa, University of California, Los Angeles, Fred Hutch Cancer Center, Parker Institute for Cancer Immunotherapy

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 37 papers. Top paper: “Regulation of CEACAM5 and Therapeutic Efficacy of an Anti-CEACAM5–SN38 Antibody–drug Conjugate in Neuroendocrine Prostate Cancer”.

Regulation of CEACAM5 and Therapeutic Efficacy of an Anti-CEACAM5–SN38 Antibody–drug Conjugate in Neuroendocrine Prostate Cancer

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-20-3396

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0DataRank · unranked

88 citations

Thomas M. Cardillo, Lisa S. Ang, Mark P. Labrecque, Ailin Zhang, James E. Hopkins +11 more

Targeting RET Kinase in Neuroendocrine Prostate Cancer

Molecular Cancer Research(2020)10.1158/1541-7786.mcr-19-1245

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51 citations

Johnny R. Ramroop, Katherine L. Morel, Song Yi Bae, Anjali V. Sheahan, Zoi E. Sychev +17 more

Response to Neoadjuvant Chemotherapy and Survival in Micropapillary Urothelial Carcinoma: Data From a Tertiary Referral Center and the Surveillance, Epidemiology, and End Results (SEER) Program

Clinical Genitourinary Cancer(2020)10.1016/j.clgc.2020.10.002

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19 citations

Sarah K. Holt, Ali Raza Khaki, Rishi Sekar, Adam J. Gadzinski, Yaw A. Nyame +17 more

An integrative oncogene-dependency map identifies unique vulnerabilities of oncogenic EGFR, KRAS, and RIT1 in lung cancer

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.03.187310

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1 citations

Naomi T. Nkinsi, Amanda K. Riley, Phoebe C. R. Parrish, Fujiko Duke, Jenny Chen +8 more

RNA Splicing Factors SRRM3 and SRRM4 Distinguish Molecular Phenotypes of Castration-Resistant Neuroendocrine Prostate Cancer

Cancer Research(2021)10.1158/0008-5472.can-21-0307

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53 citations

Lisha G. Brown, Ilsa M. Coleman, Bryce Lakely, Nicholas J. Brady, John K. Lee +13 more

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Nature Communications(2021)10.1038/s41467-021-24841-y

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49 citations

Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo +16 more

A bladder cancer patient-derived xenograft displays aggressive growth dynamics in vivo and in organoid culture

Scientific Reports(2021)10.1038/s41598-021-83662-7

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26 citations

José M. Garcia, Yuzhen Liu, Funda Vakar‐Lopez, Sonali Arora, Holly M. Nguyen +10 more

A minority of patients with functional seizures have abnormalities on neuroimaging

Journal of the Neurological Sciences(2021)10.1016/j.jns.2021.117548

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11 citations

John K. Lee, Amir H. Karimi, Hiroyuki Tatekawa, L. Brian Hickman, Michael Connerney +15 more

Clinical MRI morphological analysis of functional seizures compared to seizure-naïve and psychiatric controls

Epilepsy & Behavior(2022)10.1016/j.yebeh.2022.108858

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20 citations

Hiroyuki Tatekawa, John K. Lee, Amir H. Karimi, Siddhika S. Sreenivasan, Joseph O’Neill +15 more

Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2203410119

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8 citations

Pavlo A. Nesterenko, Jami McLaughlin, Weixian Deng, Giselle Burton Sojo, Donghui Cheng +20 more

Comprehensive Assessment of Anaplastic Lymphoma Kinase in Localized and Metastatic Prostate Cancer Reveals Targetable Alterations

Cancer Research Communications(2022)10.1158/2767-9764.crc-21-0156

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15 citations

Ilsa Coleman, Martine P. Roudier, Eric Q. Konnick, Brian Hanratty, Ruth F. Dumpit +13 more

Genomic Characterization of Prostatic Basal Cell Carcinoma

American Journal Of Pathology(2022)10.1016/j.ajpath.2022.09.010

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9 citations

Minjeong Ko, Brian Hanratty, Radhika A. Patel, Akshay Bhamidipati, Christopher M. Heaphy +11 more

Targeting advanced prostate cancer with STEAP1 chimeric antigen receptor T cell and tumor-localized IL-12 immunotherapy

Nature Communications(2023)10.1038/s41467-023-37874-2

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127 citations

Nikhil Kamat, Tiffany E. Pariva, Liting Wu, Annabelle Tsao, Koichi Sasaki +19 more

Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting

Nature Communications(2023)10.1038/s41467-023-40115-1

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104 citations

John P. Murad, Lea Christian, Jackson Gibson, Yukiko Yamaguchi, Cody Cullen +20 more

Reversible epigenetic alterations mediate PSMA expression heterogeneity in advanced metastatic prostate cancer

JCI Insight(2023)10.1172/jci.insight.162907

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82 citations

Radhika A. Patel, Ilsa M. Coleman, Martine P. Roudier, Ailin Zhang, Pallabi Mustafi +20 more

Transcriptional-translational conflict is a barrier to cellular transformation and cancer progression

Cancer Cell(2023)10.1016/j.ccell.2023.03.021

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59 citations

Sandipan Brahma, Sonali Arora, Cynthia L. Wladyka, Patrick Hoang, Steven Blinka +20 more

Metastatic Bladder Cancer Expression and Subcellular Localization of Nectin-4 and Trop-2 in Variant Histology: A Rapid Autopsy Study

Clinical Genitourinary Cancer(2023)10.1016/j.clgc.2023.05.014

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33 citations

Funda Vakar‐Lopez, Martine P. Roudier, José M. Garcia, Sonali Arora, Heather H. Cheng +10 more

Tumor-derived biomarkers predict efficacy of B7H3 antibody-drug conjugate treatment in metastatic prostate cancer models

Journal of Clinical Investigation(2023)10.1172/jci162148

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32 citations

Lei Fang, Kerry M. McGowen, JuanJuan Yin, Joel Bowman, Anson T. Ku +17 more

Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis

Communications Biology(2023)10.1038/s42003-023-04899-8

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18 citations

Jongchan Choi, Jingyi Xie, Mary E. Chaffee, Thomas M. Schmitt, Kathryn A. K. Finton +20 more

Concurrent Targeting of HDAC and PI3K to Overcome Phenotypic Heterogeneity of Castration-resistant and Neuroendocrine Prostate Cancers

Cancer Research Communications(2023)10.1158/2767-9764.crc-23-0250

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19 citations

Nathan A. Lau, Alicia Wong, Lisha G. Brown, Ilsa M. Coleman, Navonil De Sarkar +14 more

Targeting the fibroblast growth factor pathway in molecular subtypes of castration‐resistant prostate cancer

The Prostate(2023)10.1002/pros.24630

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12 citations

Lisha G. Brown, Ilsa M. Coleman, Holly M. Nguyen, Susan L. Dalrymple, W. Nathaniel Brennen +11 more

Entropic analysis of antigen-specific CDR3 domains identifies essential binding motifs shared by CDR3s with different antigen specificities

Cell Systems(2023)10.1016/j.cels.2023.03.001

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7 citations

William Chour, Diana C. DeLucia, Yapeng Su, Ana Jimena Pavlovitch-Bedzyk, Raymond T. Ng +5 more

Amygdala subfield and prefrontal cortex abnormalities in patients with functional seizures

Epilepsy & Behavior(2023)10.1016/j.yebeh.2023.109278

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5 citations

Wesley T. Kerr, John M. Stern, Yanlu Wang, Hiroyuki Tatekawa, John K. Lee +8 more

Combinatorial genetic strategy accelerates the discovery of cancer genotype-phenotype associations

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.12.536652

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4 citations

Alicia Y. W. Wong, Huiyun Sun, Vipul Bhatia, Gerardo Javier, Sujata Jana +8 more

Assessment of Cell Surface Targets in Metastatic Prostate Cancer: Expression Landscape and Molecular Correlates

Research Square(2023)10.21203/rs.3.rs-3745991/v1

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4 citations

Azra Ajkunic, Erolcan Sayar, Martine P. Roudier, Radhika A. Patel, Ilsa M. Coleman +22 more

Data from Regulation of CEACAM5 and Therapeutic Efficacy of an Anti-CEACAM5–SN38 Antibody–drug Conjugate in Neuroendocrine Prostate Cancer

(2023)10.1158/1078-0432.c.6530156.v1

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0DataRank · unranked

0 citations

Thomas M. Cardillo, Lisa S. Ang, Mark P. Labrecque, Ailin Zhang, James E. Hopkins +11 more

Assessment of TROP2, CEACAM5 and DLL3 in metastatic prostate cancer: Expression landscape and molecular correlates

npj Precision Oncology(2024)10.1038/s41698-024-00599-6

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32 citations

Erolcan Sayar, Martine P. Roudier, Radhika A. Patel, Ilsa M. Coleman, Navonil De Sarkar +24 more

PGC-1α drives small cell neuroendocrine cancer progression toward an ASCL1-expressing subtype with increased mitochondrial capacity

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2416882121

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13 citations

Chia‐Chun Chen, Jack Freeland, He Tian, Wendy Tran, Kai Song +16 more

A combinatorial genetic strategy for exploring complex genotype–phenotype associations in cancer

Nature Genetics(2024)10.1038/s41588-024-01674-1

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10 citations

Alicia Y. W. Wong, Huiyun Sun, Vipul Bhatia, Gerardo Javier, Sujata Jana +9 more

PGC-1α drives small cell neuroendocrine cancer progression towards an ASCL1-expressing subtype with increased mitochondrial capacity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.09.588489

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3 citations

Chia‐Chun Chen, Jack Freeland, He Tian, Wendy Tran, Kai Song +16 more

Advances in CAR T cell therapy: antigen selection, modifications, and current trials for solid tumors

Frontiers in Immunology(2025)10.3389/fimmu.2024.1489827

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58 citations

Yeonjoo Choi, Mysore S. Veena, John K. Lee, Daniel Sanghoon Shin, Safwaan H. Khan

Solid tumour CAR-T cells engineered with fusion proteins targeting PD-L1 for localized IL-12 delivery

Nature Biomedical Engineering(2025)10.1038/s41551-025-01509-2

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37 citations

Lea Christian, Reginaldo Cruz Alves Rosa, Yuwei Ren, Alyssa J. Buckley, Eric Hee Jun Lee +15 more

Patterns of intra- and intertumor phenotypic heterogeneity in lethal prostate cancer

Journal of Clinical Investigation(2025)10.1172/jci186599

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10 citations

Roman Gulati, Erolcan Sayar, Radhika A. Patel, Micah Tratt, Helen Richards +40 more

Modulating the PPARγ pathway upregulates NECTIN4 and enhances chimeric antigen receptor (CAR) T cell therapy in bladder cancer

Nature Communications(2025)10.1038/s41467-025-62710-0

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8 citations

Henry M. Delavan, Elizabeth Yip, Corynn Kasap, Jun Zhu, Roshan Lodha +21 more

PROX1 is an early driver of lineage plasticity in prostate cancer

Journal of Clinical Investigation(2025)10.1172/jci187490

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9 citations

Mingchen Shi, Anbarasu Kumaraswamy, Dong Lin, Dhruv Khokhani, Yong Wang +41 more

An IL-12 renaissance: Engineering tumor-restricted IL-12 to improve solid tumor T cell therapies

Molecular Therapy(2025)10.1016/j.ymthe.2025.12.018

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1 citations

John K. Lee, Saul J. Priceman, Jun Ishihara

Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.02.12.637904

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4 citations

Kai Song, Huiyun Sun, Yong Tao, Arthur Huang, Vipul Bhatia +9 more