Christopher Davies

Materials ScienceImmunology and MicrobiologyBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 22 papers. Top paper: “Mutations in penicillin-binding protein 2 from cephalosporin-resistant Neisseria gonorrhoeae hinder ceftriaxone acylation by restricting protein dynamics”.

Mutations in penicillin-binding protein 2 from cephalosporin-resistant Neisseria gonorrhoeae hinder ceftriaxone acylation by restricting protein dynamics

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.012617

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0DataRank · unranked

37 citations

Jonathan M. Turner, Joshua Tomberg, Alena Fedarovich, Magnus Unemo, Robert A. Nicholas +2 more

Development and optimization of OspC chimeritope vaccinogens for Lyme disease

Vaccine(2020)10.1016/j.vaccine.2020.01.027

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43 citations

Nathaniel S. O’Bier, Lee D. Oliver, Andrew C. Camire, Christopher G. Earnhart, DeLacy V. L. Rhodes +5 more

Molecular and Structural Analysis of Mosaic Variants of Penicillin-Binding Protein 2 Conferring Decreased Susceptibility to Expanded-Spectrum Cephalosporins in Neisseria gonorrhoeae : Role of Epistatic Mutations

UNC Libraries(2020)10.17615/92jb-wx23

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5 citations

Christopher Davies, Joshua Tomberg, Magnus Unemo, Robert A. Nicholas

Identification of Amino Acids Conferring High-Level Resistance to Expanded-Spectrum Cephalosporins in the penA Gene from Neisseria gonorrhoeae Strain H041

UNC Libraries(2020)10.17615/5xcv-6e15

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3 citations

Robert A. Nicholas, Makoto Ohnishi, Joshua Tomberg, Magnus Unemo, Christopher Davies

Alanine 501 Mutations in Penicillin-Binding Protein 2 from Neisseria gonorrhoeae : Structure, Mechanism, and Effects on Cephalosporin Resistance and Biological Fitness

UNC Libraries(2020)10.17615/szae-9y15

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3 citations

Joshua Tomberg, Leah R. Vincent, Alena Fedarovich, Robert A. Nicholas, Magnus Unemo +2 more

Unusual Conformation of the SxN Motif in the Crystal Structure of Penicillin-Binding Protein A from Mycobacterium tuberculosis

Carolina Digital Repository (University of North Carolina at Chapel Hill)(2020)10.17615/rtmc-wj48

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0 citations

Christopher Davies, Robert A. Nicholas, Alena Fedarovich

Crystal Structures of Penicillin-binding Protein 2 from Penicillin-susceptible and -resistant Strains of Neisseria gonorrhoeae Reveal an Unexpectedly Subtle Mechanism for Antibiotic Resistance

UNC Libraries(2020)10.17615/vwtk-hp70

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0 citations

Robert A. Nicholas, Ashley M. Deacon, A.J. Powell, Joshua Tomberg, Christopher Davies

High-Throughput Screening for Novel Inhibitors of Neisseria gonorrhoeae Penicillin-Binding Protein 2

UNC Libraries(2020)10.17615/2dwp-ms97

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0 citations

Yuri K. Peterson, Alena Fedarovich, Kevin A. Djordjevic, Christopher Davies, Shauna M. Swanson +1 more

Crystal Structures of Covalent Complexes of β-Lactam Antibiotics with Escherichia coli Penicillin-Binding Protein 5: Toward an Understanding of Antibiotic Specificity

UNC Libraries(2020)10.17615/sdkg-p119

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0 citations

George Nicola, Christopher Davies, Robert A. Nicholas, R. F. Pratt, Joshua Tomberg

Structural Effect of the Asp345a Insertion in Penicillin-Binding Protein 2 from Penicillin-Resistant Strains of Neisseria gonorrhoeae

UNC Libraries(2020)10.17615/eqq1-zd64

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0 citations

Alena Fedarovich, Christopher Davies, Joshua Tomberg, Edward Cook, Robert A. Nicholas

The Role of the β5–α11 Loop in the Active-Site Dynamics of Acylated Penicillin-Binding Protein A from Mycobacterium tuberculosis

UNC Libraries(2020)10.17615/9kae-xt70

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0 citations

Robert A. Nicholas, Christopher Davies, Alena Fedarovich

Mutations in PBP2 from ceftriaxone-resistant Neisseria gonorrhoeae alter the dynamics of the β3–β4 loop to favor a low-affinity drug-binding state

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101188

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23 citations

Joshua Tomberg, Carly A. Sciandra, Robert A. Nicholas, Christopher Davies, Pei Zhou +1 more

High-resolution crystal structure of theBorreliella burgdorferiPlzA protein in complex with c-di-GMP: new insights into the interaction of c-di-GMP with the novel xPilZ domain

Pathogens and Disease(2021)10.1093/femspd/ftab030

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10 citations

Jerilyn R. Izac, Edward J. A. Schuler, Dhara Patel, Christopher Davies, Richard T. Marconi +1 more

Crystal Structure of Wild-type Penicillin-binding Protein 5 from Escherichia coli: IMPLICATIONS FOR DEACYLATION OF THE ACYL-ENZYME COMPLEX

UNC Libraries(2021)10.17615/74d8-7e21

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2 citations

George Nicola, Sandra Krings, Joshua Tomberg, Robert A. Nicholas, Christopher Davies

Tetracyclines and bone: Unclear actions with potentially lasting effects

Bone(2022)10.1016/j.bone.2022.116377

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92 citations

Jessica D. Hathaway‐Schrader, Irene Lubker, Christopher Davies, Chad M. Novince, Amy J. Warner

Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6

Nature Communications(2022)10.1038/s41467-022-32613-5

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17 citations

Fei Gao, Zongyang Lv, Digant Nayak, Anindita Nayak, Priscila dos Santos Bury +11 more

Discovery of a novel transcriptional regulator of sugar catabolism in archaea

Molecular Microbiology(2023)10.1111/mmi.15114

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14 citations

Marius Ortjohann, Andreas Reinhardt, Jonathan M. Turner, Caleb Stratton, Katherine R. Weber +5 more

c‐di‐GMP regulates activity of the PlzA RNA chaperone from the Lyme disease spirochete

Molecular Microbiology(2023)10.1111/mmi.15066

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9 citations

Dhara Patel, Bruce E. Bowler, Michael T. Rothfuss, Allie J. Hall, Christopher Davies +6 more

c-di-GMP regulates RNA chaperone activity of PlzA in the Lyme disease spirochete

(2023)10.22541/au.168060960.03851580/v1

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0 citations

Taylor Van Gundy, Dhara Patel, Bruce E. Bowler, Michael T. Rothfuss, Allie J. Hall +6 more

In silico gepotidacin target mining among 33 213 global Neisseria gonorrhoeae genomes from 1928 to 2023 combined with gepotidacin MIC testing of 22 gonococcal isolates with different GyrA and ParC substitutions

Journal of Antimicrobial Chemotherapy(2024)10.1093/jac/dkae217

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11 citations

Daniel Golparian, Susanne Jacobsson, Caleb Stratton, Phạm Thị Lan, Ken Shimuta +6 more

Ureidopenicillins Are Potent Inhibitors of Penicillin-Binding Protein 2 from Multidrug-Resistant Neisseria gonorrhoeae H041

ACS Infectious Diseases(2024)10.1021/acsinfecdis.3c00713

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6 citations

Caleb M. Stratton, Sandeepchowdary Bala, María X. Cardenas-Alvarez, Robert A. Nicholas, Christopher Davies +1 more

A new class of penicillin-binding protein inhibitors to address drug-resistant Neisseria gonorrhoeae

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.27.630553

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1 citations

Allison L. Zulli, Brittany Miller, Lindsay M. Avery, Steven A. Boyd, Cassandra L. Chatwin +25 more