Isaac S. Harris

Also affiliated with University of Rochester

Biochemistry, Genetics and Molecular BiologyImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 26 papers. Top paper: “3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis”.

3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis

Molecular Cell(2020)10.1016/j.molcel.2020.10.010

N/A

6.1DataRank · unranked

201 citations

Patricia Cho, Laura M. Selfors, Hendrik J. Kuiken, Roma Kaul, Takuro Fujiwara +5 more

De Novo Pyrimidine Synthesis is a Targetable Vulnerability in IDH Mutant Glioma

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.30.470443

N/A

0.611DataRank · unranked

11 citations

Milan R. Savani, Michael M. Levitt, Adam C. Wang, Jennifer E. Endress, Cylaina Bird +38 more

Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia

iScience(2021)10.1016/j.isci.2021.102651

N/A

0.345DataRank · unranked

9 citations

Kamrine E. Poels, Cong-Hui Yao, Kimihito C. Kawabata, Gongwei Wu, Cihangir Duy +17 more

A whole food, plant-based diet reduces amino acid levels in patients with metastatic breast cancer

Cancer & Metabolism(2024)10.1186/s40170-024-00368-w

N/A

0.291DataRank · unranked

5 citations

Bradley Smith, Lisa Blanchard, Nellie Wixom, Emily Tuttle, Brian J. Altman +6 more

Cytomegalovirus-induced inactivation of TSC2 disrupts the coupling of fatty acid biosynthesis to glucose availability resulting in a vulnerability to glucose starvation

mBio(2023)10.1128/mbio.03031-23

N/A

0.286DataRank · unranked

4 citations

Irene Rodríguez-Sánchez, Xenia Schafer, Leonid Smorodintsev-Schiller, Isaac S. Harris, Joshua Munger +1 more

Targeting oncoproteins with a positive selection assay for protein degraders

Science Advances(2021)10.1126/sciadv.abd6263

N/A

0DataRank · unranked

47 citations

Leslie Duplaquet, Benjamin L. Lampson, Adam C. Wang, Amin H. Sabet, Mette Ishoey +21 more

Pharmacologic profiling reveals lapatinib as a novel antiviral against SARS-CoV-2 in vitro

Virology(2021)10.1016/j.virol.2021.11.008

N/A

0DataRank · unranked

34 citations

Jessica H. Ciesla, Morgan Monaghan, Justin Leach, Gloria Asantewaa, Leonid Smorodintsev-Schiller +7 more

De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma

Cancer Cell(2022)10.1016/j.ccell.2022.07.011

N/A

0DataRank · unranked

131 citations

Milan R. Savani, Michael M. Levitt, Adam C. Wang, Jennifer E. Endress, Cylaina Bird +46 more

Nucleotide depletion promotes cell fate transitions by inducing DNA replication stress

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.16.503984

N/A

0DataRank · unranked

6 citations

Peggy P. Hsu, Sidney Y. Vermeulen, Zhishan Wang, Taghreed Hirz, Keene L. Abbott +21 more

Regulation of antioxidants in cancer

Molecular Cell(2023)10.1016/j.molcel.2023.11.001

N/A

0DataRank · unranked

126 citations

Marco Zocchi, Fatemeh Alimohammadi, Isaac S. Harris, Fábio Hecht

Metabolic modulation of mitochondrial mass during CD4+ T cell activation

Cell chemical biology(2023)10.1016/j.chembiol.2023.08.008

N/A

0DataRank · unranked

10 citations

Dan Liang, Robert van de Ven, Peter Georgiev, Brandon M. Gassaway, SeongJun Han +15 more

Lysosomal cystine: an unexpected alarm bell for cysteine scarcity

Trends in Cell Biology(2023)10.1016/j.tcb.2023.10.009

N/A

0DataRank · unranked

4 citations

Isaac S. Harris, Fábio Hecht

A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.06.547932

N/A

0DataRank · unranked

4 citations

Veronika Horková, Joseph Longworth, Luana Guerra, Henry Kurniawan, Davide Franchina +22 more

Glutathione supports lipid abundance in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.10.524960

N/A

0DataRank · unranked

3 citations

Emily Tuttle, Nathan P. Ward, Yun Pyo Kang, Yumi Kim, Madeline E. Kavanagh +33 more

Data from Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells

(2023)10.1158/2326-6066.c.6550425.v1

N/A

0DataRank · unranked

0 citations

Jacob E. Gillis, Tara Muijlwijk, Thao H. Nguyen, Emily F. Gaudiano, Isaac S. Harris +9 more

Cytomegalovirus-induced inactivation of TSC2 disrupts the coupling of fatty acid biosynthesis to glucose availability resulting in a vulnerability to glucose limitation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.17.541212

N/A

0DataRank · unranked

0 citations

Irene Rodríguez-Sánchez, Xenia Schafer, Leonid Smorodintsev-Schiller, Isaac S. Harris, Joshua Munger +1 more

A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation

Cell Metabolism(2024)10.1016/j.cmet.2024.06.010

N/A

0DataRank · unranked

55 citations

Veronika Horková, Melanie Grusdat, Joseph Longworth, Luana Guerra, Henry Kurniawan +23 more

Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression

Nature Communications(2024)10.1038/s41467-024-50454-2

N/A

0DataRank · unranked

54 citations

Emily Tuttle, Nathan P. Ward, Yun Pyo Kang, Yumi Kim, Madeline E. Kavanagh +33 more

Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy

JCI Insight(2024)10.1172/jci.insight.174329

N/A

0DataRank · unranked

11 citations

Patrick DeLear, Prarthana Prashanth, Mete Emir Özgürses, Anteneh Tebeje, Philippa A. Burns +14 more

Catabolism of extracellular glutathione supplies amino acids to support tumor growth

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.10.617667

N/A

0DataRank · unranked

3 citations

Marco Zocchi, Emily Tuttle, Nathan P. Ward, Bradley Smith, Yun Pyo Kang +20 more

A whole food, plant-based diet reduces amino acid levels in patients with metastatic breast cancer

medRxiv(2024)10.1101/2024.10.09.24315165

N/A

0DataRank · unranked

0 citations

Bradley Smith, Lisa Blanchard, Nellie Wixom, Emily Tuttle, Brian J. Altman +6 more

MYC and Epithelial to Mesenchymal Transition (EMT) Independently Predict Circadian Rhythm Disruption in Lung Adenocarcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.15.670530

N/A

0DataRank · unranked

0 citations

Aslihan Ambeskovic, McKayla Ford, Jacob Cody Naccarato, Juliana Cazarin, Fábio Hecht +8 more

Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells

Cancer Immunology Research(2020)10.1158/2326-6066.cir-20-0384

N/A

0DataRank · unranked

180 citations

Jacob E. Gillis, Tara Muijlwijk, Thao H. Nguyen, Emily F. Gaudiano, Isaac S. Harris +9 more

Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function

Cell Metabolism(2020)10.1016/j.cmet.2020.03.004

N/A

0DataRank · unranked

244 citations

Davide Franchina, Luana Guerra, Lynn Bonetti, Leticia Soriano‐Baguet, Melanie Grusdat +27 more

Non-canonical glutamate-cysteine ligase activity protects against ferroptosis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.29.123802

N/A

0DataRank · unranked

24 citations

Andrea Mockabee‐Macias, Chang Jiang, Isaac S. Harris, Gina M. DeNicola, Yun Pyo Kang

Pharmacologic profiling reveals lapatinib as a novel antiviral against SARS-CoV-2 in vitro

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.25.398859

N/A

0DataRank · unranked

19 citations

Jessica H. Ciesla, Morgan Monaghan, Justin Leach, Gloria Asantewaa, Leonid Smorodintsev-Schiller +7 more