Hiromi Sesaki

Also affiliated with Johns Hopkins Medicine

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 36 papers. Top paper: “Asymmetrically Segregated Mitochondria Provide Cellular Memory of Hematopoietic Stem Cell Replicative History and Drive HSC Attrition”.

Asymmetrically Segregated Mitochondria Provide Cellular Memory of Hematopoietic Stem Cell Replicative History and Drive HSC Attrition

Cell stem cell(2020)10.1016/j.stem.2020.01.016

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214 citations

Jingyi He, James Bartram, José Javier, Juying Xu, Ellen Fjellman +10 more

Novel role of dynamin‐related‐protein 1 in dynamics of ER‐lipid droplets in adipose tissue

The FASEB Journal(2020)10.1096/fj.201903100rr

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45 citations

Yang Li, Zhengmei Mao, Xueyang Pan, Yueshui Zhao, Xue Gu +11 more

Hippo/Mst signaling coordinates cellular quiescence with terminal maturation in iNKT cell development and fate decisions

The Journal of Experimental Medicine(2020)10.1084/jem.20191157

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21 citations

Chaohong Liu, Yogesh Dhungana, Cliff Guy, Nicole M. Chapman, Hao Shi +4 more

Hetero-oligomerization of Rho and Ras GTPases Connects GPCR Activation to mTORC2-AKT Signaling

Cell Reports(2020)10.1016/j.celrep.2020.108427

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19 citations

May Wai, Hideaki T. Matsubayashi, Hiromi Sesaki, Miho Iijima, Hiroshi Senoo

C9orf72 regulates energy homeostasis by stabilizing mitochondrial complex I assembly

Cell Metabolism(2021)10.1016/j.cmet.2021.01.005

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154 citations

Honghe Liu, Kie Itoh, Sungtaek Oh, Liang Zhao, Daisuke Murata +5 more

Longitudinal tracking of neuronal mitochondria delineates PINK1/Parkin-dependent mechanisms of mitochondrial recycling and degradation

Science Advances(2021)10.1126/sciadv.abf6580

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44 citations

Zak Doric, Amandine Berthet, Danielle M. Jorgens, Mai K. Nguyen, Ivy Hsieh +8 more

Reduced Levels of Drp1 Protect against Development of Retinal Vascular Lesions in Diabetic Retinopathy

Cells(2021)10.3390/cells10061379

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22 citations

Hiromi Sesaki, Sayon Roy, Dongjoon Kim

Nuclear PTEN and p53 suppress stress-induced liver cancer through distinct mechanisms

Biochemical and Biophysical Research Communications(2021)10.1016/j.bbrc.2021.02.093

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15 citations

Daisuke Murata, Robert A. Anders, Hiromi Sesaki, Miho Iijima, Takashi Kato

Mitochondrial Fission Regulates Transcription of Ribosomal Protein Genes in Embryonic Hearts

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.10.430627

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2 citations

Shun Yan, Jin Lu, Danitra Parker, Huiying Wu, Qianchuang Sun +8 more

Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma

Cell Reports(2022)10.1016/j.celrep.2022.111818

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49 citations

Kee‐Beom Kim, Jennifer A. Kashatus, Nikolas Churchill, Kwon-Sik Park, Marty W. Mayo +3 more

Depletion of oocyte dynamin-related protein 1 shows maternal-effect abnormalities in embryonic development

Science Advances(2022)10.1126/sciadv.abl8070

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41 citations

In‐Won Lee, Usama Al-Zubaidi, Jun Liu, Qing-Hua Zhang, Wai Shan Yuen +6 more

Prevention and regression of megamitochondria and steatosis by blocking mitochondrial fusion in the liver

iScience(2022)10.1016/j.isci.2022.103996

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43 citations

Daisuke Murata, David E. Kleiner, Robert A. Anders, Avi Z. Rosenberg, Jeffrey Kaplan +10 more

DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism

Developmental Cell(2022)10.1016/j.devcel.2022.04.020

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31 citations

Salvador Pérez-Montero, Juan Miguel Sánchez Nieto, Aida Di Gregorio, Ana Lima, Katerina Lawlor +9 more

Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid–liquid phase separation–based method

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102822

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11 citations

Reika Kikuchi, Kenichiro Imai, Waka Kojima, Tatsuya Yamada, Miho Iijima +5 more

Drp1 regulates transcription of ribosomal protein genes in embryonic hearts

Journal of Cell Science(2022)10.1242/jcs.258956

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4 citations

Shun Yan, Jin Lu, Danitra Parker, Huiying Wu, Qianchuang Sun +8 more

The Role of the Optic Atrophy 1 (OPA1) Protein in Drug‐Induced Liver Injury

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r3945

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1 citations

Hiromi Sesaki, Yisang Yoon, Hakjoo Lee

Role of human HSPE1 for OPA1 processing independent of HSPD1

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.11.503680

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0 citations

Daisuke Murata, Miho Iijima, Hiromi Sesaki, Nelson Yeung

The mitochondrial fusion protein OPA1 is dispensable in the liver and its absence induces mitohormesis to protect liver from drug-induced injury

Nature Communications(2023)10.1038/s41467-023-42564-0

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40 citations

Tae Jin Lee, Chad A. Galloway, Wenbo Zhi, Wei Xiao, Karen L. de Mesy Bentley +5 more

Mitochondria-lysosome-related organelles mediate mitochondrial clearance during cellular dedifferentiation

Cell Reports(2023)10.1016/j.celrep.2023.113291

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31 citations

Sharon Manley, Hui Qian, Yuan Li, Chen Zhang, Kevin Li +15 more

Role of human HSPE1 for OPA1 processing independent of HSPD1

iScience(2023)10.1016/j.isci.2023.106067

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23 citations

Daisuke Murata, Miho Iijima, Hiromi Sesaki, Nelson Yeung

Partial skeletal muscle-specific Drp1 knockout enhances insulin sensitivity in diet-induced obese mice, but not in lean mice

Molecular Metabolism(2023)10.1016/j.molmet.2023.101802

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16 citations

Jared Lourie, Nicolas Berger, Nana Lin, Paul L. Nguyen, Edzana DosSantos +12 more

Blocking AMPKαS496 phosphorylation improves mitochondrial dynamics and hyperglycemia in aging and obesity

Cell chemical biology(2023)10.1016/j.chembiol.2023.09.017

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16 citations

Balamurugan Ramatchandirin, Ting Liu, Risa M. Wolf, Arisa Ikeda, Sally Radovick +5 more

A nucleotide diphosphate kinase mediates tethering between mitochondria prior to fusion

The Journal of Cell Biology(2023)10.1083/jcb.202309037

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1 citations

Miho Iijima, Hiromi Sesaki, Arisa Ikeda

Lysosomes drive the piecemeal removal of mitochondrial inner membrane

Nature(2024)10.1038/s41586-024-07835-w

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114 citations

Claudio Bussi, Antony Fearns, Mariana Capurro, Xiao‐Dong Gao, Hiromi Sesaki +3 more

Slc25a3-dependent copper transport controls flickering-induced Opa1 processing for mitochondrial safeguard

Developmental Cell(2024)10.1016/j.devcel.2024.06.008

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31 citations

Shubhrajit Roy, Svetlana Lutsenko, Miho Iijima, Hiromi Sesaki, Daisuke Murata

mCAUSE: Prioritizing mitochondrial targets that alleviate pancreatic cancer cell phenotypes

iScience(2024)10.1016/j.isci.2024.110880

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8 citations

Fumiya Ito, Gongyu Tang, Wakiko Iwata, Nelson Yeung, Junior J. West +5 more

Mechanistic insights into metabolic function of dynamin-related protein 1

Journal of Lipid Research(2024)10.1016/j.jlr.2024.100633

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7 citations

Katherine Pham, Jazmin Ysaguirre, Iqbal Mahmud, Lin Tan, Bo Wei +8 more

Systemic phospho-defective and phospho-mimetic Drp1 mice exhibit normal growth and development with altered anxiety-like behavior

iScience(2024)10.1016/j.isci.2024.109874

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6 citations

Miho Iijima, Hiromi Sesaki, Arisa Ikeda

OPA1 protects intervertebral disc and knee joint health in aged mice by maintaining the structure and metabolic functions of mitochondria

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.17.576115

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4 citations

Miriam Hernandaz-Meadows, Ashley Coleman, Kimheak Sao, Kameron L. Inguito, Owen Haslam +5 more

The loss of OPA1 accelerates intervertebral disc degeneration and osteoarthritis in aged mice

Research Square(2024)10.21203/rs.3.rs-3950044/v1

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3 citations

Vedavathi Madhu, Miriam Hernandez-Meadows, Ashley Coleman, Kimheak Sao, Kameron L. Inguito +5 more

Protocol for measuring mitochondrial size in mouse and human liver tissues

STAR Protocols(2024)10.1016/j.xpro.2024.102842

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0 citations

Miho Iijima, Arisa Ikeda, Alexia Pearah, Sally Radovick, Fredric E. Wondisford +3 more

The loss of OPA1 accelerates intervertebral disc degeneration and osteoarthritis in aged mice

Nature Communications(2025)10.1038/s41467-025-60933-9

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16 citations

Miriam Hernandez-Meadows, Ashley Coleman, Kimheak Sao, Kameron L. Inguito, Owen Haslam +6 more

Mitochondrial fission controls astrocyte morphogenesis and organization in the cortex

The Journal of Cell Biology(2025)10.1083/jcb.202410130

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6 citations

Sprihaa Kolanukuduru, Valentina Ramirez, Boyu Lyu, Gracie Manigault, Gabrielle Séjourné +4 more

Genetic disruption of mitochondrial dynamics and stasis leads to liver injury and tumorigenesis

Journal of Clinical Investigation(2025)10.1172/jci194441

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3 citations

Xiaoli Wei, Mengwei Niu, Chen Zhang, Zheyun Peng, Wanqing Liu +10 more

Context-dependent inhibitory roles of RhoA in 3D invasive cell migration within the extracellular matrix

Cell Reports(2025)10.1016/j.celrep.2025.116649

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1 citations

Yoshihiro Adachi, Junior J. West, Andrew J. Ewald, Yi Zheng, Laura D. Wood +4 more

GRHL2-HER3 and E-cadherin mediate EGFR-bypass drug resistance in lung cancer cells

Frontiers in Cell and Developmental Biology(2025)10.3389/fcell.2024.1511190

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1 citations

Wakiko Iwata, Yoshihiro Adachi, Hiromi Sesaki, Miho Iijima, Fumiya Ito