Kirill A. Afonin

University of North Carolina at Charlotte

Also affiliated with Center for Nanoscale Science and Technology

Biochemistry, Genetics and Molecular BiologyEnvironmental ScienceImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 56 papers. Top paper: “Opportunities, Barriers, and a Strategy for Overcoming Translational Challenges to Therapeutic Nucleic Acid Nanotechnology”.

Opportunities, Barriers, and a Strategy for Overcoming Translational Challenges to Therapeutic Nucleic Acid Nanotechnology

ACS Nano(2020)10.1021/acsnano.0c04753

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100 citations

Marina A. Dobrovolskaia, George M. Church, Mark Bathe, Kirill A. Afonin

Retinoic acid inducible gene-I mediated detection of bacterial nucleic acids in human microglial cells

Journal of Neuroinflammation(2020)10.1186/s12974-020-01817-1

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44 citations

Justin R. Halman, Amanda R. Burmeister, Saralynn Currin, Emil F. Khisamutdinov, Kirill A. Afonin +2 more

The immunorecognition, subcellular compartmentalization, and physicochemical properties of nucleic acid nanoparticles can be controlled by composition modification

Nucleic Acids Research(2020)10.1093/nar/gkaa908

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45 citations

Justin R. Halman, Daniel K. Miller, Joseph S Cooper, Emil F. Khisamutdinov, Ian Marriott +2 more

Characterization of Cationic Bolaamphiphile Vesicles for siRNA Delivery into Tumors and Brain

Molecular Therapy — Nucleic Acids(2020)10.1016/j.omtn.2020.02.011

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34 citations

Mathias Viard, Kirill A. Afonin, K. C. Gupta, Mary Popov, Jacqueline Salotti +5 more

Exosomes as natural delivery carriers for programmable therapeutic nucleic acid nanoparticles (NANPs)

Advanced Drug Delivery Reviews(2021)10.1016/j.addr.2021.113835

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93 citations

Kirill A. Afonin, Weina Ke

Critical review of nucleic acid nanotechnology to identify gaps and inform a strategy for accelerated clinical translation

Advanced Drug Delivery Reviews(2021)10.1016/j.addr.2021.114081

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68 citations

Marina A. Dobrovolskaia, Weina Ke, Piotr Grodzinski, Mark Bathe, Kirill A. Afonin

Nucleic acid nanoparticles (NANPs) as molecular tools to direct desirable and avoid undesirable immunological effects

Advanced Drug Delivery Reviews(2021)10.1016/j.addr.2021.04.011

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64 citations

Morgan Chandler, Kirill A. Afonin, M. Brittany Johnson

Induction of Cytokines by Nucleic Acid Nanoparticles (NANPs) Depends on the Type of Delivery Carrier

Molecules(2021)10.3390/molecules26030652

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38 citations

Morgan Chandler, Edward Cedrone, Hannah S. Newton, Melina Richardson, Jie Xu +5 more

Simultaneous silencing of lysophosphatidylcholine acyltransferases 1-4 by nucleic acid nanoparticles (NANPs) improves radiation response of melanoma cells

Nanomedicine Nanotechnology Biology and Medicine(2021)10.1016/j.nano.2021.102418

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30 citations

María Cristina Rangel, Justin R. Halman, Morgan Chandler, Luciana Nogueira de Sousa Andrade, Silvina Odete-Bustos +8 more

Programmable DNA-augmented hydrogels for controlled activation of human lymphocytes

Nanomedicine Nanotechnology Biology and Medicine(2021)10.1016/j.nano.2021.102442

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11 citations

Morgan Chandler, Alexis Manning, Kirill A. Afonin, Erdem D. Tabdanov, Alexander S. Zhovmer

Controlled Organization of Inorganic Materials Using Biological Molecules for Activating Therapeutic Functionalities

ACS Applied Materials & Interfaces(2021)10.1021/acsami.1c09230

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12 citations

Brian Minevich, Brandon K. Roark, Mathias Viard, M. Brittany Johnson, Mehedi H. Rizvi +8 more

Editorial to “Journey into the immunological properties of engineered nanomaterials: There and back again”

Advanced Drug Delivery Reviews(2021)10.1016/j.addr.2021.114100

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0 citations

Kirill A. Afonin, África González‐Fernández, Marina A. Dobrovolskaia

Artificial Immune Cell, AI‐cell , a New Tool to Predict Interferon Production by Peripheral Blood Monocytes in Response to Nucleic Acid Nanoparticles

Small(2022)10.1002/smll.202204941

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58 citations

Sankalp Jain, Justin R. Halman, Enping Hong, Marina A. Dobrovolskaia, Alexey Zakharov +2 more

Expanding Structural Space for Immunomodulatory Nucleic Acid Nanoparticles via Spatial Arrangement of Their Therapeutic Moieties

Advanced Functional Materials(2022)10.1002/adfm.202205581

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29 citations

Lewis A. Rolband, M. Brittany Johnson, Da Shi, Yelixza I. Avila, Edward Cedrone +9 more

Anhydrous Nucleic Acid Nanoparticles for Storage and Handling at Broad Range of Temperatures

Small(2022)10.1002/smll.202104814

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25 citations

Morgan Chandler, Justin R. Halman, Damian Beasock, Adam B. Fessler, Riley Q. McKeough +9 more

Biomotors, viral assembly, and RNA nanobiotechnology: Current achievements and future directions

Computational and Structural Biotechnology Journal(2022)10.1016/j.csbj.2022.11.007

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23 citations

Damian Beasock, Yang Wang, Yao-Gen Shu, Jonathan D. Dinman, Tamar Schlick +13 more

Discrimination of RNA fiber structures using solid-state nanopores

Nanoscale(2022)10.1039/d1nr08002d

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20 citations

Morgan Chandler, Christopher Maffeo, Ali Fallahi, Amr Makhamreh, Justin R. Halman +4 more

Adaptation‐Proof SARS‐CoV‐2 Vaccine Design

Advanced Functional Materials(2022)10.1002/adfm.202206055

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14 citations

Brianna Hnath, Brendan Rackley, Jian Wang, Abhinay Gontu, Morgan Chandler +6 more

Adaptation-proof SARS-CoV-2 vaccine design

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.17.492310

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3 citations

Brianna Hnath, Brendan Rackley, Jian Wang, Abhinay Gontu, Morgan Chandler +6 more

Artificial immune cell, AI-cell , a new tool to predict interferon production by peripheral blood monocytes in response to nucleic acid nanoparticles

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.28.501902

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2 citations

Sankalp Jain, Justin R. Halman, Enping Hong, Marina A. Dobrovolskaia, Alexey Zakharov +2 more

Editorial to “Molecular engineering of biomaterials programmed to operate in living systems”

Advanced Drug Delivery Reviews(2022)10.1016/j.addr.2022.114669

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0 citations

Nikolay V. Dokholyan, Kirill A. Afonin

Therapeutic immunomodulation by rationally designed nucleic acids and nucleic acid nanoparticles

Frontiers in Immunology(2023)10.3389/fimmu.2023.1053550

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22 citations

Elizabeth Skelly, Damian Beasock, Ian Marriott, M. Brittany Johnson, Jacqueline Salotti +2 more

Optical, structural, and biological properties of silver nanoclusters formed within the loop of a C-12 hairpin sequence

Nanoscale Advances(2023)10.1039/d3na00092c

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14 citations

Nolan Marshall, Liam Yourston, Lewis A. Rolband, Damian Beasock, Leyla Danai +4 more

Change in Lipofectamine Carrier as a Tool to Fine-Tune Immunostimulation of Nucleic Acid Nanoparticles

Molecules(2023)10.3390/molecules28114484

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13 citations

Yasmine Radwan, Jie Xu, Jeffrey D. Clogston, Marina A. Dobrovolskaia, Kirill A. Afonin +1 more

Demonstrating the Synthesis and Antibacterial Properties of Nanostructured Silver

Journal of Chemical Education(2023)10.1021/acs.jchemed.3c00125

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9 citations

Varsha Godakhindi, Juan L. Vivero‐Escoto, Kirill A. Afonin, Lewis A. Rolband

Characterization of RNA Nanoparticles and Their Dynamic Properties Using Atomic Force Microscopy

Methods in molecular biology(2023)10.1007/978-1-0716-3417-2_12

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4 citations

Yelixza I. Avila, Kirill A. Afonin, Alexey V. Krasnoslobodtsev, Alexander Lushnikov

Toehold-Mediated Shape Transition of Nucleic Acid Nanoparticles

ACS Applied Materials & Interfaces(2023)10.1021/acsami.3c01604

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10 citations

Nathan McCann, Erwin Doe, Hannah Hayth, Kheiria Benkato, M. Brittany Johnson +4 more

Nanoscale metal-organic frameworks for the delivery of nucleic acids to cancer cells

International Journal of Pharmaceutics X(2023)10.1016/j.ijpx.2023.100161

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7 citations

Morgan Chandler, Yelixza I. Avila, Sandra I Arroyo-Becker, G. Patriarche, Antonio Vargas‐Berenguel +4 more

Structural Characterization of Nucleic Acid Nanoparticles Using SAXS and SAXS-Driven MD

Methods in molecular biology(2023)10.1007/978-1-0716-3417-2_4

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6 citations

Kriti Chopra, Lewis A. Rolband, Leyla Danai, Shirish Chodankar, Lin Yang +2 more

Structural Characterization of DNA-Templated Silver Nanoclusters by Energy Dispersive Spectroscopy

Methods in molecular biology(2023)10.1007/978-1-0716-3417-2_10

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6 citations

Kirill A. Afonin, Damian Beasock

cGAS Mediates the Inflammatory Responses of Human Microglial Cells to Genotoxic DNA Damage

Inflammation(2023)10.1007/s10753-023-01946-8

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6 citations

Yasmine Radwan, Christine Richardson, Shan Yan, Kirill A. Afonin, Ian Marriott +1 more

Synthesis of DNA-Templated Silver Nanoclusters and the Characterization of Their Optical Properties and Biological Activity

Methods in molecular biology(2023)10.1007/978-1-0716-3417-2_21

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2 citations

Lewis A. Rolband, Damian Beasock, Kirill A. Afonin, Elizabeth Skelly

Characterization of PAMAM Dendrimers for the Delivery of Nucleic Acid Nanoparticles

Methods in molecular biology(2023)10.1007/978-1-0716-3417-2_17

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2 citations

Laura Rebolledo, Melanie Andrade-Muñoz, Kirill A. Afonin, Yelixza I. Avila

RNA nanoparticles for targeted therapies of triple-negative breast cancers

Molecular Therapy — Nucleic Acids(2023)10.1016/j.omtn.2023.08.013

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2 citations

Eva J. Ge, Kirill A. Afonin, Leyla Danai

Anticoagulant Activity of Nucleic Acid Nanoparticles (NANPs) Assessed by Thrombin Generation Dynamics on a Fully Automated System

Methods in molecular biology(2023)10.1007/978-1-0716-3417-2_23

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4 citations

Bárbara Gomes Barion, Tânia Rúbia Flores da Rocha, Alex Rolband, Kirill A. Afonin, Roger Chammas +1 more

Small Volume Microrheology to Evaluate Viscoelastic Properties of Nucleic Acid-Based Supra-Assemblies

Methods in molecular biology(2023)10.1007/978-1-0716-3417-2_11

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1 citations

Joel Petersen, Elizabeth Skelly, Kirill A. Afonin, Alexey V. Krasnoslobodtsev, A. K. Gupta

Aptamer Conjugated RNA/DNA Hybrid Nanostructures Designed for Efficient Regulation of Blood Coagulation

Methods in molecular biology(2023)10.1007/978-1-0716-3417-2_19

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1 citations

Weina Ke, Kirill A. Afonin, Lewis A. Rolband

Dynamic Nanostructures for Conditional Activation and Deactivation of Biological Pathways

Methods in molecular biology(2023)10.1007/978-1-0716-3417-2_22

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1 citations

Laura P. Rebolledo, Martin Panigaj, Kirill A. Afonin, Yasmine Radwan

Editorial: Delivering nucleic acids to immune and non-immune cells

Frontiers in Immunology(2023)10.3389/fimmu.2023.1237506

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1 citations

Francesca Re, Diana Boraschi, Kirill A. Afonin

Special Issue “Nanotechnology to Overcome the World’s Most Critical Health Issues: Liposomes and Beyond—A Themed Issue Dedicated to Professor Yechezkel Barenholz”

Molecules(2023)10.3390/molecules28124788

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0 citations

Kirill A. Afonin, Marina A. Dobrovolskaia

Assessment of Intracellular Compartmentalization of RNA Nanostructures

Methods in molecular biology(2023)10.1007/978-1-0716-3417-2_14

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0 citations

Kirill A. Afonin, M. Brittany Johnson, Yasmine Radwan

Discriminating Immunorecognition Pathways Activated by RNA Nanostructures

Methods in molecular biology(2023)10.1007/978-1-0716-3417-2_15

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0 citations

M. Brittany Johnson, Kirill A. Afonin, Leyla Danai

Cracking the Code: Enhancing Molecular Tools for Progress in Nanobiotechnology

ACS Applied Bio Materials(2024)10.1021/acsabm.4c00432

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8 citations

Laura P. Rebolledo, Elizabeth Skelly, Renata de Freitas Saito, Hui Wei, David M.J. Lilley +16 more

Immunostimulatory nucleic acid nanoparticles (NANPs) augment protective osteoblast and osteoclast type I interferon responses to Staphylococcus aureus

Nanomedicine Nanotechnology Biology and Medicine(2024)10.1016/j.nano.2024.102762

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7 citations

Yelixza I. Avila, Damian Beasock, Yasmine Radwan, Samantha R. Suptela, Ian Marriott +3 more

The Reduction of Traumatic Spinal Cord Secondary Injury by Anti-RhoA siRNA Functionalized Nucleic Acid Nanoparticles (NANPs)

RNA NanoMed(2024)10.59566/isrnn.2024.0101079

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1 citations

Damian Beasock, Morgan Chandler, Yasmine Radwan, Martin Panigaj, Zhen Liao +5 more

A Piecewise Design Approach to Engineering a Miniature ACE2 Mimic to Bind SARS-CoV-2

ACS Applied Bio Materials(2024)10.1021/acsabm.4c00222

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3 citations

Brianna Hnath, Jian Wang, Morgan Chandler, Arnab Mukherjee, Neela H. Yennawar +4 more

Design and Characterization of Compact, Programmable, Multistranded Nonimmunostimulatory Nucleic Acid Nanoparticles Suitable for Biomedical Applications

Biochemistry(2024)10.1021/acs.biochem.3c00615

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2 citations

Leyla Danai, Abigail Coffman, Yasmine Radwan, M. P. Teter, Hannah Hayth +9 more

A modular platform for nucleic acid-driven multimerization of nanobodies for advanced molecular imaging

Molecular Therapy — Nucleic Acids(2024)10.1016/j.omtn.2024.102367

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0 citations

Nathalia Leal Santos, Kirill A. Afonin, Laura P. Rebolledo

Changes in Generations of PAMAM Dendrimers and Compositions of Nucleic Acid Nanoparticles Govern Delivery and Immune Recognition

ACS Biomaterials Science & Engineering(2025)10.1021/acsbiomaterials.5c00336

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9 citations

Laura P. Rebolledo, Nathalia Leal Santos, Brandon Rawlins, Yasmine Radwan, Melanie Andrade-Muñoz +7 more

Nucleic Acid Nanoparticles Redefine Traditional Regulatory Terminology: The Blurred Line between Active Pharmaceutical Ingredients and Excipients

ACS Nano Medicine(2025)10.1021/acsnanomed.5c00070

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7 citations

Martin Panigaj, Laura Rebolledo, Hari Bhaskaran, Kirill A. Afonin, Seraphim Kozlov

Chemical Composition and Backbone Modifications Define Deformability of Nucleic Acid Nanoparticles

ACS Nano(2025)10.1021/acsnano.5c04293

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6 citations

Martin Panigaj, Yasmine Radwan, Hemani Chhabra, Yu Chen, Aleksei Aksimentiev +3 more

Autonomous Nucleic Acid and Protein Nanocomputing Agents Engineered to Operate in Living Cells

ACS Nano(2025)10.1021/acsnano.4c13663

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10 citations

Tanaya Basu Roy, Elizabeth Skelly, Morgan Chandler, Jian Wang, E. Srinivasan +4 more

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

Advanced Functional Materials(2025)10.1002/adfm.202508122

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6 citations

Anh Ha, Morgan Chandler, Nathalia Leal Santos, Tae‐Jin Kim, Hannah S. Newton +3 more

From Sequence to Response: AI‐Guided Prediction of Nucleic Acid Nanoparticles Immune Recognitions

Small(2025)10.1002/smll.202509459

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6 citations

Sankalp Jain, Jessica Shea, Quinton Krueger, Erwin Doe, Daniel K. Miller +8 more

Nucleic acid nanobiosystems for cancer theranostics: an overview of emerging trends and challenges

Nanomedicine(2025)10.1080/17435889.2025.2501919

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3 citations

Luciana Nogueira de Sousa Andrade, Marcio C. Bajgelman, Lawrence Banks, XANDRA O. BREAKEFIELD, Marina A. Dobrovolskaia +10 more

Spatially Organized DNA-templated Silver Nanoclusters as Potent Antimicrobial Agents for ESKAPE Infections

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.02.680010

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2 citations

Krishna Majithia, Laura P. Rebolledo, Camila Rizek, Sílvia Figueiredo Costa, Alora R. Dunnavant +9 more