Xiaodong Cheng

Also affiliated with The University of Texas MD Anderson Cancer Center, Third Hospital of Hebei Medical University, Nanjing Hydraulic Research Institute

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 46 papers. Top paper: “Characterization of SETD3 methyltransferase–mediated protein methionine methylation”.

Characterization of SETD3 methyltransferase–mediated protein methionine methylation

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.014072

N/A

0.883DataRank · unranked

17 citations

Matthew V. Holt, J.R. Horton, Clayton B. Woodcock, Anamika Patel, Xing Zhang +4 more

Structural basis for the substrate specificity of Helix pomatia AMP deaminase and a chimeric ADGF adenosine deaminase

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110357

N/A

0.104DataRank · unranked

1 citations

J.R. Horton, George Tzertzinis, Jujun Zhou, Ira Schildkraut, Xiaodong Cheng +1 more

KRAB domain of ZFP568 disrupts TRIM28-mediated abnormal interactions in cancer cells

NAR Cancer(2020)10.1093/narcan/zcaa007

N/A

0DataRank · unranked

22 citations

Gundeep Kaur, Ren Ren, Yue Lu, Kevin Lin, Jia Li +7 more

Beta class amino methyltransferases from bacteria to humans: evolution and structural consequences

Nucleic Acids Research(2020)10.1093/nar/gkaa446

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0DataRank · unranked

37 citations

J.R. Horton, Xing Zhang, Robert Blumenthal, Xiaodong Cheng, Clayton B. Woodcock

A Role for N6-Methyladenine in DNA Damage Repair

Trends in Biochemical Sciences(2020)10.1016/j.tibs.2020.09.007

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0DataRank · unranked

27 citations

Robert Blumenthal, Xiaodong Cheng, Xing Zhang

The inactive Dnmt3b3 isoform preferentially enhances Dnmt3b-mediated DNA methylation

Genes & Development(2020)10.1101/gad.341925.120

N/A

0DataRank · unranked

91 citations

Ren Ren, Gundeep Kaur, Swanand Hardikar, Zhengzhou Ying, Lance Babcock +5 more

METTL5, an 18S rRNA-specific m 6 A methyltransferase, modulates expression of stress response genes

(2020)10.1101/2020.04.27.064162

N/A

0DataRank · unranked

16 citations

Qi Liu, Dan Yu, Kundhavai Natchiar, Chen Zhou, Chih-Hung Hsu +7 more

ZNF410 uniquely activates the NuRD component CHD4 to silence fetal hemoglobin expression

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.31.274324

N/A

0DataRank · unranked

4 citations

Ren Ren, Ruopeng Feng, Lana C. Ly, Yemin Lan, Zhe Zhang +15 more

Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia

Nature Cancer(2021)10.1038/s43018-021-00249-x

N/A

0DataRank · unranked

288 citations

Kathryn Keenan, Mark Cockerill, Wendy A. Kellner, Alexandra Stowell, Christian Sherk +57 more

MBD5 and MBD6 couple DNA methylation to gene silencing through the J-domain protein SILENZIO

Science(2021)10.1126/science.abg6130

N/A

0DataRank · unranked

92 citations

Brandon A. Boone, Luke Strauskulage, C. Jake Harris, Gundeep Kaur, Matthew A. Gladstone +9 more

Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions

Nucleic Acids Research(2021)10.1093/nar/gkab460

N/A

0DataRank · unranked

74 citations

J.R. Horton, Jie Yang, Taraneh Hajian, Masoud Vedadi, Cari A. Sagum +5 more

Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor.

Apollo (University of Cambridge)(2021)10.17863/cam.74923

N/A

0DataRank · unranked

63 citations

Chun‐Wei Chen, Venkatasubramaniam Sundaramurthy, Mikołaj Słabicki, Dapeng Hao, Caroline J. Watson +20 more

Structural basis for human ZBTB7A action at the fetal globin promoter

Cell Reports(2021)10.1016/j.celrep.2021.109759

N/A

0DataRank · unranked

32 citations

Ren Ren, Lana C. Ly, J.R. Horton, Fudong Li, Kate Quinlan +4 more

Clostridioides difficile specific DNA adenine methyltransferase CamA squeezes and flips adenine out of DNA helix

Nature Communications(2021)10.1038/s41467-021-23693-w

N/A

0DataRank · unranked

30 citations

J.R. Horton, Robert Blumenthal, Xing Zhang, Xiaodong Cheng, Jujun Zhou

Preferential CEBP binding to T:G mismatches and increased C-to-T human somatic mutations

Nucleic Acids Research(2021)10.1093/nar/gkab276

N/A

0DataRank · unranked

19 citations

J.R. Horton, Kadir C. Akdemir, Jia Li, Yun Huang, Janani Kumar +4 more

Chemoproteomic study uncovers HemK2/KMT9 as a new target for NTMT1 bisubstrate inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.13.439666

N/A

0DataRank · unranked

0 citations

Ying Meng, Dan Yu, Nicholas Noinaj, Xiaodong Cheng, Rong Huang +1 more

Structural characterization of dicyanopyridine containing DNMT1-selective, non-nucleoside inhibitors

Structure(2022)10.1016/j.str.2022.03.009

N/A

0DataRank · unranked

33 citations

Sarath Pathuri, Kristen Wong, Ren Ren, Lourdes Rueda, David T. Fosbenner +7 more

Mediating and maintaining methylation while minimizing mutation: Recent advances on mammalian DNA methyltransferases

Current Opinion in Structural Biology(2022)10.1016/j.sbi.2022.102433

N/A

0DataRank · unranked

14 citations

Robert Blumenthal, Xiaodong Cheng

Enzymatic characterization of mRNA cap adenosine-N6 methyltransferase PCIF1 activity on uncapped RNAs

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.101751

N/A

0DataRank · unranked

15 citations

Nan Dai, Eric J. Wolf, Ivan R. Corrêa, Jujun Zhou, Tao P. Wu +4 more

Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence

Journal of Medicinal Chemistry(2022)10.1021/acs.jmedchem.2c01789

N/A

0DataRank · unranked

10 citations

J.R. Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu +12 more

A complete methyl-lysine binding aromatic cage constructed by two domains of PHF2

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102862

N/A

0DataRank · unranked

6 citations

Jujun Zhou, Qin Chen, Xing Zhang, Mark T. Bedford, Xiaodong Cheng +1 more

GSK-3484862 targets DNMT1 for degradation in cells

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.03.514954

N/A

0DataRank · unranked

1 citations

Yang Zeng, Jee Won Hwang, Bigang Liu, Nan Dai, Ivan R Corrêa +6 more

Deficient regulation of the epithelial Na + channel (ENaC) activity and impaired urinary conservation of Na + in Epac1 ‐/‐ and Epac2 ‐/‐ mice

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r3539

N/A

0DataRank · unranked

0 citations

Viktor Tomilin, Kyrylo Pyrshev, Anna Stavniichuk, Fang Mei, Xiaodong Cheng +2 more

GSK-3484862 targets DNMT1 for degradation in cells

NAR Cancer(2023)10.1093/narcan/zcad022

N/A

0DataRank · unranked

54 citations

Bigang Liu, Yang Zeng, Jee Won Hwang, Nan Dai, Ivan R Corrêa +6 more

Structures of CTCF–DNA complexes including all 11 zinc fingers

Nucleic Acids Research(2023)10.1093/nar/gkad594

N/A

0DataRank · unranked

44 citations

J.R. Horton, Bin Liu, Victor G. Corces, Robert Blumenthal, Xing Zhang +2 more

Structural basis for transcription factor ZBTB7A recognition of DNA and effects of ZBTB7A somatic mutations that occur in human acute myeloid leukemia

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.102885

N/A

0DataRank · unranked

17 citations

J.R. Horton, Qin Chen, Jie Yang, Bin Liu, Yun Huang +4 more

C2H2 Zinc Finger Transcription Factors Associated with Hemoglobinopathies

Journal of Molecular Biology(2023)10.1016/j.jmb.2023.168343

N/A

0DataRank · unranked

14 citations

Fangfang Xia, Xiaotian Zhang, Robert Blumenthal, Xiaodong Cheng, Xing Zhang

Allosteric autoregulation of DNA binding via a DNA-mimicking protein domain: a biophysical study of ZNF410–DNA interaction using small angle X-ray scattering

Nucleic Acids Research(2023)10.1093/nar/gkac1274

N/A

0DataRank · unranked

13 citations

Ren Ren, Michal Hammel, J.R. Horton, Jie Yang, Yu Cao +8 more

Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase

ACS Chemical Biology(2023)10.1021/acschembio.3c00035

N/A

0DataRank · unranked

7 citations

Youchao Deng, Iredia D. Iyamu, J.R. Horton, Dan Yu, Taraneh Hajian +8 more

Biochemical and structural characterization of the first-discovered metazoan DNA cytosine-N4 methyltransferase from the bdelloid rotifer Adineta vaga

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105017

N/A

0DataRank · unranked

6 citations

J.R. Horton, Gundeep Kaur, Qin Chen, Xuwen Li, Fabian Mendoza +5 more

The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.15.571946

N/A

0DataRank · unranked

2 citations

Ren Ren, Zhengzhou Ying, J.R. Horton, Matthew D. Bramble, Bin Liu +7 more

Updated understanding of the protein–DNA recognition code used by C2H2 zinc finger proteins

Current Opinion in Structural Biology(2024)10.1016/j.sbi.2024.102836

N/A

0DataRank · unranked

34 citations

Robert Blumenthal, Xiaodong Cheng, Xing Zhang

Quinoline-based compounds can inhibit diverse enzymes that act on DNA

Cell chemical biology(2024)10.1016/j.chembiol.2024.09.007

N/A

0DataRank · unranked

8 citations

Qin Chen, Ren Ren, Jie Yang, Bigang Liu, J.R. Horton +14 more

DNA-binding proteins from MBD through ZF to BEN: recognition of cytosine methylation status by one arginine with two conformations

Nucleic Acids Research(2024)10.1093/nar/gkae832

N/A

0DataRank · unranked

7 citations

Robert Blumenthal, Xiaodong Cheng, Xing Zhang

SART3 reads methylarginine-marked glycine- and arginine-rich motifs

Cell Reports(2024)10.1016/j.celrep.2024.114459

N/A

0DataRank · unranked

5 citations

Jujun Zhou, Wei He, Rongjie Fu, Leilei Shi, Ngoc Khoi Dang +5 more

TREX2 deficiency suppresses spontaneous and genotoxin-associated mutagenesis

Cell Reports(2024)10.1016/j.celrep.2023.113637

N/A

0DataRank · unranked

3 citations

Mi‐Young Son, Xiaodong Cheng, Jun Ho Ko, Patrick Sung, Paul Hasty +1 more

Keep Fingers on the CpG Islands

Epigenomes(2024)10.3390/epigenomes8020023

N/A

0DataRank · unranked

1 citations

Robert Blumenthal, Xiaodong Cheng, Xing Zhang

One form and two functions: MBD of SETDB2 is a protein-interacting domain

Structure(2024)10.1016/j.str.2024.01.009

N/A

0DataRank · unranked

1 citations

Taiping Chen, Xiaodong Cheng, Jujun Zhou

Brain and cancer associated binding domain mutations provide insight into CTCF’s relationship with chromatin and its ability to act as a chromatin organizer

Research Square(2024)10.21203/rs.3.rs-4670379/v1

N/A

0DataRank · unranked

1 citations

Catherine Do, Guimei Jiang, Giulia Cova, Christos C. Katsifis, Domenic N. Narducci +12 more

Dual histone methyl reader ZCWPW1 facilitates repair of meiotic double strand breaks in male mice

eLife(2020)10.7554/elife.53360

N/A

0DataRank · unranked

47 citations

Jacob Paiano, Melania Bruno, Wei Wu, Sarath Pathuri, Xing Zhang +5 more

Multimeric transcription factor BCL11A utilizes two zinc-finger tandem arrays to bind clustered short sequence motifs

Nature Communications(2025)10.1038/s41467-025-58998-7

N/A

0DataRank · unranked

9 citations

Meigen Yu, Jujun Zhou, Melody Tran, Rithvi R Anakal, Yue Lu +6 more

Structure–Activity Relationship Studies of DNA Methyltransferase 1 Monovalent Degraders

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.4c02161

N/A

0DataRank · unranked

5 citations

Youngeun Lee, Yulin Han, Yue Zhong, Jujun Zhou, Joel Hrit +9 more

GSK-3484862, a DNMT1 degrader, promotes DNMT3B expression in lung cancer cells

NAR Cancer(2025)10.1093/narcan/zcaf018

N/A

0DataRank · unranked

5 citations

Swanand Hardikar, Kimie Kondo, Nan Dai, Ivan R Corrêa, Mo Yu +5 more

Nuclear poly(A)-binding protein and nucleolin utilize their RNA recognition motifs to read PAR chains

Nucleic Acids Research(2025)10.1093/nar/gkaf1090

N/A

0DataRank · unranked

2 citations

Morgan Dasovich, J.R. Horton, Hongrui Liu, Qiansheng Zhan, Swarnalatha Manickavinayaham +9 more

Quinoline-based compounds can inhibit diverse enzymes that act on DNA

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.03.587980

N/A

0DataRank · unranked

0 citations

Qin Chen, Ren Ren, Jie Yang, Bigang Liu, J.R. Horton +13 more

Biochemical and structural basis for YTH domain of human YTHDC1 binding to methylated adenine in DNA

Nucleic Acids Research(2020)10.1093/nar/gkaa604

N/A

0DataRank · unranked

47 citations

J.R. Horton, Jujun Zhou, Mark T. Bedford, Robert Blumenthal, Xing Zhang +2 more