🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Galina I. Lepesheva

Vanderbilt University

ORCID: 0000-0002-6975-1131
MedicinePharmacology, Toxicology and PharmaceuticsChemistryBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile
0Author DataRank

Indexed papers

0in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 13 papers. Top paper: “A requirement for an active proton delivery network supports a compound I-mediated C–C bond cleavage in CYP51 catalysis”.

A requirement for an active proton delivery network supports a compound I-mediated C–C bond cleavage in CYP51 catalysis

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.014064
N/A
1.1DataRank · unranked
38 citations

Z. Wawrzak, F. Peter Guengerich, Galina I. Lepesheva, Tatiana Y. Hargrove

The Clinically Approved Antifungal Drug Posaconazole Inhibits Human Cytomegalovirus Replication

Antimicrobial Agents and Chemotherapy(2020)10.1128/aac.00056-20
N/A
0DataRank · unranked
37 citations

Anna Luganini, Marta Celegato, Giorgio Palù, Giorgio Gribaudo, Galina I. Lepesheva +2 more

The antifungal drug isavuconazole inhibits the replication of human cytomegalovirus (HCMV) and acts synergistically with anti-HCMV drugs

Antiviral Research(2021)10.1016/j.antiviral.2021.105062
N/A
0DataRank · unranked
8 citations

Marta Celegato, Anna Luganini, Giorgio Gribaudo, Galina I. Lepesheva, Arianna Loregian +1 more

Unravelling the role of transient redox partner complexes in P450 electron transfer mechanics

Scientific Reports(2022)10.1038/s41598-022-20671-0
N/A
0DataRank · unranked
13 citations

David C. Lamb, Jarrod A. Smith, Z. Wawrzak, Steven L. Kelly, Galina I. Lepesheva +1 more

P450 electron transfer mechanics: unravelling the evolutionary role of transient redox protein complexes

Research Square(2022)10.21203/rs.3.rs-1816943/v1
N/A
0DataRank · unranked
0 citations

Tatiana Y. Hargrove, David C. Lamb, Jarrod A. Smith, Z. Wawrzak, Steven L. Kelly +1 more

Processive kinetics in the three-step lanosterol 14α-demethylation reaction catalyzed by human cytochrome P450 51A1

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104841
N/A
0DataRank · unranked
21 citations

Molly E. Sullivan, Yasuhiro Tateishi, Tatiana Y. Hargrove, Galina I. Lepesheva, F. Peter Guengerich +1 more

Structural modeling of cytochrome P450 51 from a deep-sea fish points to a novel structural feature in other CYP51s

Journal of Inorganic Biochemistry(2023)10.1016/j.jinorgbio.2023.112241
N/A
0DataRank · unranked
6 citations

David C. Lamb, Steven L. Kelly, Galina I. Lepesheva, John J. Stegeman, Jared V. Goldstone

A First-in-Class Pyrazole-isoxazole Enhanced Antifungal Activity of Voriconazole: Synergy Studies in an Azole-Resistant Candida albicans Strain, Computational Investigation and in Vivo Validation in a Galleria mellonella Fungal Infection Model

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01109
N/A
0DataRank · unranked
13 citations

Pasquale Russomanno, Simona Barone, B Botella Mateu, Antonella Ilenia Alfano, Martina Miranda +12 more

Oxygen‐18 Labeling Reveals a Mixed Fe−O Mechanism in the Last Step of Cytochrome P450 51 Sterol 14α‐Demethylation

Angewandte Chemie International Edition(2024)10.1002/anie.202317711
N/A
0DataRank · unranked
24 citations

Yasuhiro Tateishi, Tatiana Y. Hargrove, Galina I. Lepesheva, F. Peter Guengerich, Kevin D. McCarty

Unique structural features in a deep-sea CYP51 relate to high pressure adaptation

Research Square(2024)10.21203/rs.3.rs-5589110/v1
N/A
0DataRank · unranked
0 citations

Tatiana Y. Hargrove, David C. Lamb, Z. Wawrzak, G. Minasov, Jared V. Goldstone +3 more

A bypass gateway from cholesterol to sex steroid biosynthesis circumnavigates CYP17A1

Nature Communications(2025)10.1038/s41467-025-66558-2
N/A
0DataRank · unranked
4 citations

Yoon-Mi Chung, Mohammad Alyamani, Yijing Dai, Kevin D. McCarty, Evan Roberts +13 more

Concerning P450 Evolution: Structural Analyses Support Bacterial Origin of Sterol 14α-Demethylases

Molecular Biology and Evolution(2020)10.1093/molbev/msaa260
N/A
0DataRank · unranked
39 citations

Tatiana Y. Hargrove, Bin Zhao, Z. Wawrzak, Jared V. Goldstone, William David Nes +5 more

Unique Structural Features Relate to Evolutionary Adaptation of Cytochrome P450 in the Abyssal Zone

International Journal of Molecular Sciences(2025)10.3390/ijms26125689
N/A
0DataRank · unranked
1 citations

David C. Lamb, Z. Wawrzak, G. Minasov, Jared V. Goldstone, Steven L. Kelly +3 more