P. R. Watson

Biochemistry, Genetics and Molecular BiologyMedicineAgricultural and Biological Sciences

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 20 papers. Top paper: “Structural analysis of histone deacetylase 8 mutants associated with Cornelia de Lange Syndrome spectrum disorders”.

Structural analysis of histone deacetylase 8 mutants associated with Cornelia de Lange Syndrome spectrum disorders

Journal of Structural Biology(2020)10.1016/j.jsb.2020.107681

N/A

0.533DataRank · unranked

9 citations

Nicholas J. Porter, Christophe Decroos, Matthew S. Lee, P. R. Watson, Sarah E. Raible +4 more

A Novel Zinc Binding Group for HDAC6 Inhibition

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r3604

N/A

0.430DataRank · unranked

12 citations

P. R. Watson, Beate König, Finn K. Hansen, David W. Christianson, Abigail D. Cragin

Investigation of All Disease-Relevant Lysine Acetylation Sites in α-Synuclein Enabled by Non-canonical Amino Acid Mutagenesis

eLife(2025)10.7554/elife.109043

N/A

0.110DataRank · unranked

1 citations

Minghao Li, Grace Park, Jennifer Ramirez, Hudson Lee, P. R. Watson +10 more

Aromatic C‐F Interactions Influence Binding Mode of Inhibitors in HDAC6

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r2257

N/A

0DataRank · unranked

0 citations

Jacob M. Hooker, David W. Christianson, P. R. Watson

Difluoromethyl-1,3,4-oxadiazoles Are Selective, Mechanism-Based, and Essentially Irreversible Inhibitors of Histone Deacetylase 6

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c01345

N/A

0DataRank · unranked

48 citations

P. R. Watson, Nina Reßing, Abigail D. Cragin, Linda Schäker‐Hübner, David W. Christianson +2 more

Structure and Function of Kdac1, a Class II Deacetylase from the Multidrug-Resistant Pathogen Acinetobacter baumannii

Biochemistry(2023)10.1021/acs.biochem.3c00288

N/A

0DataRank · unranked

9 citations

David W. Christianson, P. R. Watson

Crystal structure of histone deacetylase 6 complexed with (R)-lipoic acid, an essential cofactor in central carbon metabolism

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105228

N/A

0DataRank · unranked

9 citations

Juana Goulart Stollmaier, David W. Christianson, P. R. Watson

Macrocyclic Octapeptide Binding and Inferences on Protein Substrate Binding to Histone Deacetylase 6

ACS Chemical Biology(2023)10.1021/acschembio.3c00113

N/A

0DataRank · unranked

7 citations

Suchetana Gupta, Parisa Hosseinzadeh, Benjamin P. Brown, David Baker, David W. Christianson +1 more

Crystal Structure of Histone Deacetylase 6 Complexed with ( R )-Lipoic Acid, an Essential Cofactor in Central Carbon Metabolism

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.08.552419

N/A

0DataRank · unranked

3 citations

Juana Goulart Stollmaier, David W. Christianson, P. R. Watson

Difluoromethyl-1,3,4-oxadiazoles are selective, mechanism-based, and essentially irreversible inhibitors of histone deacetylase 6

ChemRxiv(2023)10.26434/chemrxiv-2023-6kt1w-v3

N/A

0DataRank · unranked

2 citations

P. R. Watson, Nina Reßing, Abigail D. Cragin, Linda Schäker‐Hübner, David W. Christianson +2 more

Difluoromethyl-1,3,4-oxadiazoles are selective, mechanism-based, and essentially irreversible inhibitors of histone deacetylase 6

ChemRxiv(2023)10.26434/chemrxiv-2023-6kt1w-v4

N/A

0DataRank · unranked

1 citations

P. R. Watson, Nina Reßing, Abigail D. Cragin, Linda Schäker‐Hübner, David W. Christianson +2 more

Difluoromethyl-1,3,4-oxadiazoles are selective, mechanism-based, and essentially irreversible inhibitors of histone deacetylase 6

ChemRxiv(2023)10.26434/chemrxiv-2023-6kt1w

N/A

0DataRank · unranked

0 citations

P. R. Watson, Nina Reßing, Abigail D. Cragin, Linda Schäker‐Hübner, David W. Christianson +2 more

Difluoromethyl-1,3,4-oxadiazoles are selective, mechanism-based, and essentially irreversible inhibitors of histone deacetylase 6

ChemRxiv(2023)10.26434/chemrxiv-2023-6kt1w-v2

N/A

0DataRank · unranked

0 citations

P. R. Watson, Nina Reßing, Abigail D. Cragin, Linda Schäker‐Hübner, David W. Christianson +2 more

Design, Synthesis, and Structural Evaluation of Acetylated Phenylthioketone Inhibitors of HDAC10

ACS Medicinal Chemistry Letters(2024)10.1021/acsmedchemlett.4c00293

N/A

0DataRank · unranked

4 citations

P. R. Watson, David W. Christianson, Juana Goulart Stollmaier

Exploring Alternative Zinc-Binding Groups in Histone Deacetylase (HDAC) Inhibitors Uncovers DS-103 as a Potent Ethylhydrazide-Based HDAC Inhibitor with Chemosensitizing Properties

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.4c02373

N/A

0DataRank · unranked

13 citations

Lukas Biermann, P. R. Watson, Jingyu Li, Beate König, Matthew N. Gaynes +11 more

Investigation of Disease-Relevant Lysine Acetylation Sites in α-Synuclein Enabled by Non-canonical Amino Acid Mutagenesis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.21.634178

N/A

0DataRank · unranked

5 citations

Minghao Li, Grace Park, Jennifer Ramirez, Hudson Lee, P. R. Watson +10 more

Integrating computational design with crystallographic validation

Methods in enzymology on CD-ROM/Methods in enzymology(2025)10.1016/bs.mie.2025.08.030

N/A

0DataRank · unranked

0 citations

Fátima Pardo‐Ávila, Parisa Hosseinzade, P. R. Watson

Investigation of All Disease-Relevant Lysine Acetylation Sites in α-Synuclein Enabled by Non-canonical Amino Acid Mutagenesis

eLife(2025)10.7554/elife.109043.1

N/A

0DataRank · unranked

0 citations

Minghao Li, Grace Park, Jennifer Ramirez, Hudson Lee, P. R. Watson +10 more

Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites

Nature Communications(2021)10.1038/s41467-021-23609-8

N/A

0DataRank · unranked

95 citations

P. R. Watson, Timothy W. Craven, Xinting Li, Stephen Rettie, Fátima Pardo‐Ávila +13 more

Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6

Biochemistry(2022)10.1021/acs.biochem.2c00332

N/A

0DataRank · unranked

10 citations

Ping Bai, Changning Wang, Abigail D. Cragin, Jacob M. Hooker, David W. Christianson +1 more