Bruce A. Posner

The University of Texas Southwestern Medical Center

Biochemistry, Genetics and Molecular BiologyComputer ScienceMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 35 papers. Top paper: “Aryl Sulfonamide Inhibits Entry and Replication of Diverse Influenza Viruses via the Hemagglutinin Protein”.

Aryl Sulfonamide Inhibits Entry and Replication of Diverse Influenza Viruses via the Hemagglutinin Protein

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00304

N/A

0.449DataRank · unranked

19 citations

Matthew A. Esparza, Jue Liang, Prasanna Bhat, Jacinth Naidoo, Briana L. McGovern +9 more

GSK3 inhibition reduces ECM production and prevents age-related macular degeneration–like pathology

JCI Insight(2024)10.1172/jci.insight.178050

N/A

0.321DataRank · unranked

7 citations

Antonio Ortega, Gracen E. Collier, Steffi Daniel, Krista N. Thompson, Melissa K. McCoy +3 more

Covalent inhibition of the SARS-CoV-2 NiRAN domain via an active-site cysteine

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.108378

N/A

0.181DataRank · unranked

2 citations

Adam Osinski, Abir Majumdar, Jennifer L. Eitson, Monika I. Antczak, Krzysztof Pawłowski +7 more

Contrasting interferon-mediated antiviral responses in human lung adenocarcinoma cells

Journal of Virology(2025)10.1128/jvi.00469-25

N/A

0.104DataRank · unranked

1 citations

Sara S. El Zahed, Umut Karakus, Hanspeter Niederstrasser, Boning Gao, Kimberly Batten +9 more

Concerted cell and in vivo screen for pancreatic ductal adenocarcinoma (PDA) chemotherapeutics

Scientific Reports(2020)10.1038/s41598-020-77373-8

N/A

0DataRank · unranked

3 citations

Shreoshi Pal Choudhuri, Ozhan Ocal, Yalda Zolghadri, Victor Pashkov, Hanspeter Niederstrasser +9 more

Total synthesis of (+)-spiroindimicin A and congeners unveils their antiparasitic activity

Chemical Science(2021)10.1039/d1sc02838c

N/A

0DataRank · unranked

26 citations

S. Ray, Leah S. Imlay, Lauren T. Callaghan, Hanspeter Niederstrasser, Prema L. Mallipeddi +5 more

Chemical screening identifies novel small molecule activators of natural killer cell cytotoxicity against cancer cells

Cancer Immunology Immunotherapy(2021)10.1007/s00262-021-03117-w

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0DataRank · unranked

7 citations

Sheela Karunanithi, Bruce A. Posner, Hanspeter Niederstrasser, Hong Cheng, Yuriy Federov +6 more

Total Synthesis of (+)-Spiroindimicin A via Asymmetric Palladium-Catalyzed Spirocyclization

ChemRxiv(2021)10.26434/chemrxiv.14515014.v1

N/A

0DataRank · unranked

1 citations

S. Ray, Leah S. Imlay, Lauren Callaghan, Hanspeter Niederstrasser, Prema L. Mallipeddi +5 more

Total Synthesis of (+)-Spiroindimicin A via Asymmetric Palladium-Catalyzed Spirocyclization

ChemRxiv(2021)10.26434/chemrxiv.14515014

N/A

0DataRank · unranked

0 citations

S. Ray, Leah S. Imlay, Lauren Callaghan, Hanspeter Niederstrasser, Prema L. Mallipeddi +5 more

Repurposed dihydroorotate dehydrogenase inhibitors with efficacy against drug-resistant Acinetobacter baumannii

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2213116119

N/A

0DataRank · unranked

16 citations

Timothy C. Umland, Xiaoyi Deng, Farah El Mazouni, Sreekanth Kokkonda, Ruth Olson +11 more

Targeting ESR1 mutation–induced transcriptional addiction in breast cancer with BET inhibition

JCI Insight(2022)10.1172/jci.insight.151851

N/A

0DataRank · unranked

11 citations

Qian Wang, Sunil Kumar, Venkat S. Malladi, Szu‐Yuan Wu, Shuguang Wei +19 more

Small Molecule-mediated Insulin Hypersecretion Induces Transient ER Stress Response and Loss of Beta Cell Function

Endocrinology(2022)10.1210/endocr/bqac081

N/A

0DataRank · unranked

5 citations

Gitanjali Roy, Derk D. Binns, Magdalena Grzemska, Luiz F. Barella, Fiona Armoo +7 more

Small molecule-mediated insulin hypersecretion induces transient unfolded protein response and loss of beta cell function

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.07.482881

N/A

0DataRank · unranked

0 citations

Gitanjali Roy, Derk D. Binns, Magdalena Grzemska, Luiz F. Barella, Fiona Armoo +7 more

A fast-killing tyrosine amide (( S )-SW228703) with blood and liver-stage antimalarial activity associated with the Cyclic Amine Resistance Locus ( Pf CARL)

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.16.512381

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0DataRank · unranked

0 citations

Aloysus K. Lawong, Suraksha Gahalawat, Ashwani Kumar, Chao Xing, Nimisha Mittal +12 more

IDR-targeting compounds suppress HPV genome replication via disruption of phospho-BRD4 association with DNA damage response factors

Molecular Cell(2023)10.1016/j.molcel.2023.11.022

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0DataRank · unranked

28 citations

Hsien‐Tsung Lai, N. Sanjib Banerjee, Zonghui Ma, Juan F. Santana, Shuguang Wei +11 more

Fast-Killing Tyrosine Amide (( S )-SW228703) with Blood- and Liver-Stage Antimalarial Activity Associated with the Cyclic Amine Resistance Locus ( Pf CARL)

ACS Infectious Diseases(2023)10.1021/acsinfecdis.2c00527

N/A

0DataRank · unranked

10 citations

Aloysus K. Lawong, Suraksha Gahalawat, Ashwani Kumar, Chao Xing, Nimisha Mittal +12 more

Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules

Cell chemical biology(2023)10.1016/j.chembiol.2023.07.017

N/A

0DataRank · unranked

7 citations

Min Fang, Jiwoong Kim, Baiyun Wang, Elisa Lin, Vishal Khivansara +16 more

LIMS-Kinase provides sensitive and generalizable label-free in vitro measurement of kinase activity using mass spectrometry

Cell Reports Physical Science(2023)10.1016/j.xcrp.2023.101599

N/A

0DataRank · unranked

2 citations

Melissa K. McCoy, Lianbo Li, Bruce A. Posner, Kenneth D. Westover, Cynthia J. Meyer

Modular Total Synthesis of the 5/5-Spirocyclic Spiroindimicins

ChemRxiv(2023)10.26434/chemrxiv-2023-zcrr5

N/A

0DataRank · unranked

3 citations

Tiffany A. Brisco, S. Ray, Arani Datta, Xiaoyu Zhang, Zhen Zhang +8 more

A cholesterol-binding bacterial toxin provides a strategy for identifying a specific Scap inhibitor that blocks lipid synthesis in animal cells

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2318024121

N/A

0DataRank · unranked

12 citations

Jared Smothers, Daphne Rye, Shreya Endapally, Hong Chen, Shili Li +6 more

Benzoxazole-derivatives enhance progranulin expression and reverse the aberrant lysosomal proteome caused by GRN haploinsufficiency

Nature Communications(2024)10.1038/s41467-024-50076-8

N/A

0DataRank · unranked

8 citations

Charlotte Guhl, Gordon C. Werthmann, Danielle Dixon, Basar Cenik, Yesu Addepalli +9 more

Synergistic and antagonistic drug interactions are prevalent but not conserved across acute myeloid leukemia cell lines

Research Square(2024)10.21203/rs.3.rs-4159724/v1

N/A

0DataRank · unranked

0 citations

Fatma N. Kalkan, Mustafa Yıldız, N. Ezgi Wood, Michael Farid, Melissa K. McCoy +5 more

Synthesis of the 5/5-spiroindimicin alkaloids: development of a general synthetic approach and biological investigations

Organic & Biomolecular Chemistry(2024)10.1039/d4ob01552e

N/A

0DataRank · unranked

0 citations

Tiffany A. Brisco, S. Ray, Arani Datta, Xiaoyu Zhang, Zhen Zhang +8 more

Synergistic and antagonistic drug interactions are prevalent but not conserved across acute myeloid leukemia cell lines

Scientific Reports(2025)10.1038/s41598-025-03242-x

N/A

0DataRank · unranked

4 citations

Muhammed Sadik Yildiz, N. Ezgi Wood, Michael Farid, Melissa K. McCoy, Milo M. Lin +5 more

Identification of α-Azacyclic Acetamide-Based Inhibitors of P. falciparum Na + Pump ( Pf ATP4) with Fast-Killing Asexual Blood-Stage Antimalarial Activity by Phenotypic Screening

ACS Infectious Diseases(2025)10.1021/acsinfecdis.5c00436

N/A

0DataRank · unranked

3 citations

Leah S. Imlay, Vandana Thathy, Kate J. Fairhurst, Adele M. Lehane, Aloysus K. Lawong +13 more

Benchmarking and optimizing Perturb-seq in differentiating human pluripotent stem cells

Stem Cell Reports(2025)10.1016/j.stemcr.2025.102713

N/A

0DataRank · unranked

1 citations

Yihan Wang, Sean C. Goetsch, Vrushali Pandit, Lei Wang, Huan Zhao +29 more

Benchmarking and optimizing Perturb-seq in differentiating human pluripotent stem cells

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.21.633969

N/A

0DataRank · unranked

2 citations

Yihan Wang, Sean C. Goetsch, Vrushali Pandit, Lei Wang, Huan Zhao +29 more

Select azo compounds post-translationally modulate HTRA1 abundance and activity potentially through interactions at the trimer interface

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.13.651909

N/A

0DataRank · unranked

0 citations

Seungje Jeon, Sofia Bali, Sophia M. DiCesare, Ali Abbas, Steffi Daniel +8 more

Identification of α-azacyclic acetamide-based inhibitors of P. falciparum Na + pump ( Pf ATP4) with fast-killing asexual blood-stage antimalarial activity by phenotypic screening

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.20.655166

N/A

0DataRank · unranked

0 citations

Leah S. Imlay, Vandana Thathy, Kate J. Fairhurst, Adele M. Lehane, Aloysus K. Lawong +13 more

Select Azo Compounds Post-translationally Modulate HTRA1 Abundance and Activity Potentially through Interactions at the Trimer Interface

ACS Chemical Biology(2025)10.1021/acschembio.4c00818

N/A

0DataRank · unranked

0 citations

Seungje Jeon, Sofia Bali, Sophia M. DiCesare, Ali Abbas, Steffi Daniel +8 more

Interaction between the autophagy protein Beclin 1 and Na+,K+-ATPase during starvation, exercise, and ischemia

JCI Insight(2020)10.1172/jci.insight.133282

N/A

0DataRank · unranked

53 citations

Yang Liu, Vanessa Ginet, Mingjun Shi, Jihoon Nah, Zhongju Zou +11 more

Identification of BET inhibitors (BETi) against solitary fibrous tumor (SFT) through high-throughput screening (HTS)

Neoplasia(2025)10.1016/j.neo.2025.101244

N/A

0DataRank · unranked

0 citations

David S. Moura, Yi Li, Jesús M. López Martí, Paulino Gómez‐Puertas, John T. Nguyen +7 more

Chemical intervention of influenza virus mRNA nuclear export

PLoS Pathogens(2020)10.1371/journal.ppat.1008407

N/A

0DataRank · unranked

19 citations

Amir Mor, Hanspeter Niederstrasser, Kris M. White, Alexander D. White, Ke Zhang +14 more

Simultaneous Control of Endogenous and User-Defined Genetic Pathways Using Unique ecDHFR Pharmacological Chaperones

Cell chemical biology(2020)10.1016/j.chembiol.2020.03.006

N/A

0DataRank · unranked

14 citations

DaNae R. Woodard, Steffi Daniel, Hui Peng, Prema L. Mallipeddi, Hanspeter Niederstrasser +6 more

Single-cell-level screening method for migratory cancer cells and its potential feasibility in high-throughput manner

Biofabrication(2020)10.1088/1758-5090/ab9315

N/A

0DataRank · unranked

6 citations

Hanspeter Niederstrasser, Rami Barakat, Zaid Haddadin, Sandra Rose Miller, Bruce A. Posner +2 more