Timothy J. Purwin

Biochemistry, Genetics and Molecular BiologyMedicineImmunology and Microbiology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Merged pdf from ErbB3 Targeting Enhances the Effects of MEK Inhibitor in Wild-Type BRAF/NRAS Melanoma

(2023)10.1158/0008-5472.22419945

Top 100%

0DataRank

Top 100%0 citations

Timothy J. Purwin, Shea A. Heilman, Inna Chervoneva, Peter A. McCue, Adam C. Berger +5 more

Papers

Driven by 25 papers — median percentile 0. Top paper: “Metabolic Adaptations to MEK and CDK4/6 Cotargeting in Uveal Melanoma”.

Metabolic Adaptations to MEK and CDK4/6 Cotargeting in Uveal Melanoma

Molecular Cancer Therapeutics(2020)10.1158/1535-7163.mct-19-1016

N/A

0.524DataRank · unranked

32 citations

Timothy J. Purwin, Anna Han, Vivian Chua, Prem Patel, Usman Baqai +7 more

Gene signature reveals decreased SOX10-dependent transcripts in malignant cells from immune checkpoint inhibitor-resistant cutaneous melanomas

iScience(2023)10.1016/j.isci.2023.107472

N/A

0.438DataRank · unranked

11 citations

Signe Caksa, Ahmet Saçan, Claudia Capparelli, Andrew E. Aplin, Timothy J. Purwin

BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors

Oncogene(2020)10.1038/s41388-020-01554-y

N/A

0DataRank · unranked

48 citations

Timothy J. Purwin, Nelisa Bechtel, Connie Liao, Vivian Chua, Erin L. Seifert +6 more

Targeting BRD/BET proteins inhibits adaptive kinome upregulation and enhances the effects of BRAF/MEK inhibitors in melanoma

British Journal of Cancer(2020)10.1038/s41416-019-0724-y

N/A

0DataRank · unranked

27 citations

Claudia Capparelli, Dan A. Erkes, Timothy J. Purwin, Shea A. Heilman, Adam C. Berger +3 more

Roles of the BAP1 Tumor Suppressor in Cell Metabolism

Cancer Research(2021)10.1158/0008-5472.can-20-3430

N/A

0DataRank · unranked

59 citations

Timothy J. Purwin, Andrew E. Aplin, Anna Han

SOX10 requirement for melanoma tumor growth is due, in part, to immune-mediated effects

Cell Reports(2021)10.1016/j.celrep.2021.110085

N/A

0DataRank · unranked

39 citations

Manoela Tiago, Signe Caksa, Claudia Capparelli, Timothy J. Purwin, Gaurav Kumar +6 more

Correction to: BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors

Oncogene(2021)10.1038/s41388-021-01645-4

N/A

0DataRank · unranked

2 citations

Timothy J. Purwin, Nelisa Bechtel, Connie Liao, Vivian Chua, Erin L. Seifert +6 more

Targeting SOX10-deficient cells to reduce the dormant-invasive phenotype state in melanoma

Nature Communications(2022)10.1038/s41467-022-28801-y

N/A

0DataRank · unranked

100 citations

Timothy J. Purwin, McKenna Q. Glasheen, Signe Caksa, Manoela Tiago, Nicole A. Wilski +17 more

A Genome-Wide Screen Identifies PDPK1 as a Target to Enhance the Efficacy of MEK1/2 Inhibitors in NRAS Mutant Melanoma

Cancer Research(2022)10.1158/0008-5472.can-21-3217

N/A

0DataRank · unranked

26 citations

Mai Q. Nguyen, Nicole A. Wilski, Timothy J. Purwin, Mégane Vernon, Manoela Tiago +2 more

Pyruvate dehydrogenase inactivation causes glycolytic phenotype in BAP1 mutant uveal melanoma

Oncogene(2022)10.1038/s41388-021-02154-0

N/A

0DataRank · unranked

16 citations

Vivian Chua, Usman Baqai, Timothy J. Purwin, Nelisa Bechtel, Emily Hunter +7 more

Multi‐omics profiling shows BAP1 loss is associated with upregulated cell adhesion molecules in uveal melanoma

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.l7442

N/A

0DataRank · unranked

0 citations

Timothy J. Purwin, Vivian Chua, Anna Han, Nelisa Bechtel, Edward J. Hartsough +4 more

SOX10 Loss Sensitizes Melanoma Cells to Cytokine-Mediated Inflammatory Cell Death

Molecular Cancer Research(2023)10.1158/1541-7786.mcr-23-0290

N/A

0DataRank · unranked

13 citations

Signe Caksa, Casey D. Stefanski, Isabella V. Trachtenberg, Haley P. Wilson, Nicole A. Wilski +9 more

Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105418

N/A

0DataRank · unranked

7 citations

Alison Kurimchak, Isabella V. Trachtenberg, Timothy J. Purwin, Jelan I. Haj, Anna Han +10 more

Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth

Cancers(2023)10.3390/cancers15133451

N/A

0DataRank · unranked

10 citations

Dzmitry Mukha, Vivian Chua, Timothy J. Purwin, Manoela Tiago, Bhavik Modasia +15 more

Merged pdf from ErbB3 Targeting Enhances the Effects of MEK Inhibitor in Wild-Type BRAF/NRAS Melanoma

(2023)10.1158/0008-5472.22419945

Top 100%

0DataRank

Top 100%0 citations

Timothy J. Purwin, Shea A. Heilman, Inna Chervoneva, Peter A. McCue, Adam C. Berger +5 more

Merged pdf from ErbB3 Targeting Enhances the Effects of MEK Inhibitor in Wild-Type BRAF/NRAS Melanoma

INDIGO (University of Illinois at Chicago)(2023)10.1158/0008-5472.22419945.v1

Top 100%

0DataRank

Top 100%0 citations

Timothy J. Purwin, Shea A. Heilman, Inna Chervoneva, Peter A. McCue, Adam C. Berger +5 more

Data from Response and Resistance to Paradox-Breaking BRAF Inhibitor in Melanomas In Vivo and Ex Vivo

(2023)10.1158/1535-7163.c.6539317

N/A

0DataRank · unranked

0 citations

Curtis H. Kugel, Michael J. Vido, Adam C. Berger, Timothy J. Purwin, Allison Goldberg +6 more

Slow proliferation of BAP1-deficient uveal melanoma cells is associated with reduced S6 signaling and resistance to nutrient stress

Science Signaling(2024)10.1126/scisignal.adn8376

N/A

0DataRank · unranked

6 citations

Melisa Lopez-Anton, Mizue Terai, Ryota Tanaka, Usman Baqai, Timothy J. Purwin +13 more

Lineage commitment pathways epigenetically oppose oncogenic Gαq/11-YAP1 signaling in dormant disseminated uveal melanoma

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.05.583565

N/A

0DataRank · unranked

1 citations

Melisa Lopez Anton, Timothy J. Purwin, Lornella Seeneevassen, Vivian Chua, Francis Waltrich +10 more

Selective USP7 Inhibition Synergizes with MEK1/2 Inhibitor to Enhance Immune Responses and Potentiate Anti–PD-1 Therapy in NRAS-Mutant Melanoma

Journal of Investigative Dermatology(2025)10.1016/j.jid.2025.03.021

N/A

0DataRank · unranked

9 citations

Dinghao Wang, Timothy J. Purwin, Sophia Ran, Qi Yang, Qingrun Zhang +2 more

Elevated Transglutaminase-2 in SOX10-Deficient Melanoma Promotes Tumor Onset and Decreases Intratumoral CD4+ T Cells

Cancer Research(2025)10.1158/0008-5472.can-24-3267

N/A

0DataRank · unranked

2 citations

Timothy J. Purwin, Dan A. Erkes, Kristen M. DeRosa, Erica Kitterman, Samantha M. Barnada +13 more

Targeting TAZ-TEAD in minimal residual disease enhances the duration of targeted therapy in melanoma models

Nature Communications(2025)10.1038/s41467-025-64682-7

N/A

0DataRank · unranked

2 citations

Timothy J. Purwin, Panyu Chen, Somenath Chowdhury, George L. Mellor, K.X. Luo +10 more

FOXD3 Regulates VISTA Expression in Melanoma

Cell Reports(2020)10.1016/j.celrep.2019.12.036

N/A

0DataRank · unranked

85 citations

Meghan Knecht, Mehri Mollaee, Zhijiu Zhong, Dan A. Erkes, Peter A. McCue +9 more

Pyroptosis Modulates Multiple Immune Cell Populations in Targeted Therapy–Treated Melanoma

Cancer Immunology Research(2025)10.1158/2326-6066.cir-25-0444

N/A

0DataRank · unranked

2 citations

Dan A. Erkes, Timothy J. Purwin, Diana S. Melissaratos, Casey D. Stefanski, Signe Caksa +7 more

Targeting PHGDH Upregulation Reduces Glutathione Levels and Resensitizes Resistant NRAS-Mutant Melanoma to MAPK Kinase Inhibition

Journal of Investigative Dermatology(2020)10.1016/j.jid.2020.02.047

N/A

0DataRank · unranked

43 citations

Jessica L.F. Teh, Timothy J. Purwin, Inna Chervoneva, Michael A. Davies, Katherine L. Nathanson +5 more

Timothy J. Purwin

Indexed papers

Top data-sharing exemplar

Papers