Jeffrey R. Holt

Also affiliated with Boston Children's Hospital, Harvard University, Boston Children's Museum

NeuroscienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 18 papers. Top paper: “Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels”.

Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels

eLife(2023)10.7554/elife.89719

N/A

0.536DataRank · unranked

14 citations

Wei-Hsiang Weng, Katie S. Kindt, Hui Ho Vanessa Chang, Jonathan S. Montgomery, Evan M. Ratzan +12 more

Single and Dual Vector Gene Therapy with AAV9-PHP.B Rescues Hearing in Tmc1 Mutant Mice

Molecular Therapy(2020)10.1016/j.ymthe.2020.11.016

N/A

0DataRank · unranked

81 citations

Paola Solanes, Carl Nist-Lund, Sofia Spataro, Olga Shubina-Oleinik, Irina Marcovich +4 more

Evolution and function of Tmc genes in mammalian hearing

Current Opinion in Physiology(2020)10.1016/j.cophys.2020.06.011

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0DataRank · unranked

22 citations

Jeffrey R. Holt, Irina Marcovich

A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear

UNC Libraries(2020)10.17615/trz2-j317

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0DataRank · unranked

0 citations

Konstantina M. Stanković, Sarah Wassmer, Lukas D. Landegger, Luk H. Vandenberghe, Sarah D. Gluck +6 more

Putting the Pieces Together: the Hair Cell Transduction Complex

Journal of the Association for Research in Otolaryngology(2021)10.1007/s10162-021-00808-0

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0DataRank · unranked

25 citations

Mélanie Tobin, Johannes Elferich, Eric Gouaux, Ángela Ballesteros, Zhiqiang Yan +3 more

Optimized AAV Vectors for TMC1 Gene Therapy in a Humanized Mouse Model of DFNB7/11

Biomolecules(2022)10.3390/biom12070914

N/A

0DataRank · unranked

30 citations

Nicholas K. Baer, Olga Shubina-Oleinik, Rachel J. Eclov, Clayton W. Beard, Jeffrey R. Holt +1 more

Hearing Preservation and Spatial Hearing Outcomes After Cochlear Implantation in Children With TMPRSS3 Mutations

Otology & Neurotology(2022)10.1097/mao.0000000000003747

N/A

0DataRank · unranked

2 citations

Alejandro García, Shelly P. Godar, Jeffrey R. Holt, Daniel J. Lee, Ruth Y. Litovsky +1 more

TMEM63 proteins function as monomeric high-threshold mechanosensitive ion channels

Neuron(2023)10.1016/j.neuron.2023.07.006

N/A

0DataRank · unranked

84 citations

Shaun Rawson, Zhangfei Shen, Elakkiya Tamilselvan, Harper E. Smith, Julia Halford +7 more

Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.26.542533

N/A

0DataRank · unranked

10 citations

Wei-Hsiang Weng, Katie S. Kindt, Hui Ho Vanessa Chang, Jonathan S. Montgomery, Evan M. Ratzan +12 more

TMC function, dysfunction, and restoration in mouse vestibular organs

Frontiers in Neurology(2024)10.3389/fneur.2024.1356614

N/A

0DataRank · unranked

16 citations

John Lee, Margot A. Madison, Hong Zhu, Wu Zhou, Gwenaëlle S. G. Géléoc +2 more

Sensory transduction in auditory hair cells—PIEZOs can’t touch this

The Journal of General Physiology(2024)10.1085/jgp.202413585

N/A

0DataRank · unranked

10 citations

Robert Fettiplace, Ulrich Müller, Jeffrey R. Holt

Structural and functional basis of mechanosensitive TMEM63 channelopathies

Neuron(2025)10.1016/j.neuron.2025.05.009

N/A

0DataRank · unranked

11 citations

Augustus J. Lowry, Harper E. Smith, Jiale Xie, Shaun Rawson, Chen Wang +6 more

Mammalian TMC1 or 2 are necessary for scramblase activity in auditory hair cells

Hearing Research(2025)10.1016/j.heares.2025.109229

N/A

0DataRank · unranked

10 citations

Irina Marcovich, Cristobal von Muhlenbrock Rodriguez, S. O'Malley, Runjia Cui, Ángela Ballesteros +2 more

Endocochlear potential contributes to hair cell death in TMPRSS3 hearing loss

Journal of Clinical Investigation(2025)10.1172/jci186395

N/A

0DataRank · unranked

6 citations

Yuan-Siao Chen, Stephanie L. Rouse, Xiaohan Wang, Janmaris Marin Fermin, Kevin T. Booth +13 more

A contemporary view of mechanosensory transduction in auditory hair cells

Biophysical Journal(2025)10.1016/j.bpj.2025.06.015

N/A

0DataRank · unranked

3 citations

Jeffrey R. Holt, Matthew Mun

Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels

eLife(2025)10.7554/elife.89719.3

N/A

0DataRank · unranked

0 citations

Wei-Hsiang Weng, Katie S. Kindt, Hui Ho Vanessa Chang, Jonathan S. Montgomery, Evan M. Ratzan +12 more

The Mechanosensory Transduction Machinery in Inner Ear Hair Cells

Annual Review of Biophysics(2020)10.1146/annurev-biophys-062420-081842

N/A

0DataRank · unranked

111 citations

Jeffrey R. Holt, Zheng Wang

TMEM145 is a Principal Component of Outer Hair Cell Stereocilia

SSRN Electronic Journal(2025)10.2139/ssrn.5279354

N/A

0DataRank · unranked

0 citations

Marisa Flook, Antonia Löhnes, Sherylanne Newton, Vijay Renigunta, Saskia Hanemaaijer +6 more