William F. Elmquist

Also affiliated with United States Food and Drug Administration, Johns Hopkins University

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 31 papers. Top paper: “Methodological and analytical considerations for intra-operative microdialysis”.

Methodological and analytical considerations for intra-operative microdialysis

Fluids and Barriers of the CNS(2023)10.1186/s12987-023-00497-2

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0.453DataRank · unranked

7 citations

Karishma Rajani, Masum Rahman, Ju‐Hee Oh, Desmond Brown, Jaclyn F. White +8 more

β-Cyclodextrin-Poly (β-Amino Ester) Nanoparticles Are a Generalizable Strategy for High Loading and Sustained Release of HDAC Inhibitors

ChemRxiv(2020)10.26434/chemrxiv.12037335.v1

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0 citations

Martha Fowler, Afroz S. Mohammad, Wenqui Zhang, Cassandra Baker, Colton Broughton +5 more

β-Cyclodextrin-Poly (β-Amino Ester) Nanoparticles Are a Generalizable Strategy for High Loading and Sustained Release of HDAC Inhibitors

ChemRxiv(2020)10.26434/chemrxiv.12037335

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0DataRank · unranked

0 citations

Martha Fowler, Afroz S. Mohammad, Wenqui Zhang, Cassandra Baker, Colton Broughton +5 more

Brain Distribution of Berzosertib: An Ataxia Telangiectasia and Rad3-Related Protein Inhibitor for the Treatment of Glioblastoma

Journal of Pharmacology and Experimental Therapeutics(2021)10.1124/jpet.121.000845

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45 citations

Wenjuan Zhang, Danielle M. Burgenske, Minjee Kim, Afroz S. Mohammad, Sonja Dragojevic +5 more

Efflux Limits Tumor Drug Delivery Despite Disrupted BBB

Trends in Pharmacological Sciences(2021)10.1016/j.tips.2021.03.001

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19 citations

Jann N. Sarkaria, William F. Elmquist, Jessica I. Griffith

Factors Influencing Luciferase-Based Bioluminescent Imaging in Preclinical Models of Brain Tumor

Drug Metabolism and Disposition(2021)10.1124/dmd.121.000597

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12 citations

Shiv K. Gupta, Wenjuan Zhang, Surabhi Talele, Afroz S. Mohammad, Janice K. Laramy +5 more

Methods for intratumoral microdialysis probe targeting and validation in murine brain tumor models

Journal of Neuroscience Methods(2021)10.1016/j.jneumeth.2021.109321

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5 citations

Ian Olson, Joshua J. Jacobs, Cécile Riviere-Cazaux, Kirsten Burns, Lucas P. Carlstrom +8 more

Changes in the vasculature of human brain tumors: Implications for treatment

Neuro-Oncology(2021)10.1093/neuonc/noab220

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3 citations

Surabhi Talele, Jann N. Sarkaria, William F. Elmquist, Wenjuan Zhang

Activation of STAT3 through combined SRC and EGFR signaling drives resistance to a mitotic kinesin inhibitor in glioblastoma

Cell Reports(2022)10.1016/j.celrep.2022.110991

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31 citations

Athanassios Dovas, Michael Argenziano, Christian T. Meyer, Lauren Stopfer, Matei A. Banu +13 more

Convection enhanced delivery of EGFR targeting antibody-drug conjugates Serclutamab talirine and Depatux-M in glioblastoma patient-derived xenografts

Neuro-Oncology Advances(2022)10.1093/noajnl/vdac130

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13 citations

Michael S. Regan, Jessica I. Griffith, Sonia Jain, Sylwia A. Stopka, Danielle M. Burgenske +19 more

Central Nervous System Delivery of the Catalytic Subunit of DNA-Dependent Protein Kinase Inhibitor Peposertib as Radiosensitizer for Brain Metastases

Journal of Pharmacology and Experimental Therapeutics(2022)10.1124/jpet.121.001069

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16 citations

Wenjuan Zhang, Ju‐Hee Oh, Danielle M. Burgenske, Ann C. Mladek, Sonja Dragojevic +3 more

Murine Central Nervous System and Bone Marrow Distribution of the Aurora A Kinase Inhibitor Alisertib: Pharmacokinetics and Exposure at the Sites of Efficacy and Toxicity

Journal of Pharmacology and Experimental Therapeutics(2022)10.1124/jpet.122.001268

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16 citations

Erica A. Power, Wenjuan Zhang, David J. Daniels, William F. Elmquist, Ju‐Hee Oh

Central Nervous System Distribution of the Ataxia-Telangiectasia Mutated Kinase Inhibitor AZD1390: Implications for the Treatment of Brain Tumors

Journal of Pharmacology and Experimental Therapeutics(2022)10.1124/jpet.122.001230

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11 citations

Wenjuan Zhang, Jiajia Chen, Shiv K. Gupta, Danielle M. Burgenske, Jann N. Sarkaria +2 more

Delivery versus Potency in Treating Brain Tumors: BI-907828, a MDM2-p53 Antagonist with Limited BBB Penetration but Significant In Vivo Efficacy in Glioblastoma

Molecular Cancer Therapeutics(2023)10.1158/1535-7163.mct-23-0217

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8 citations

Rachael A. Vaubel, Ju-Hee Oh, Ann C. Mladek, Surabhi Talele, Wenqiu Zhang +5 more

Overcoming translational barriers in H3K27-altered diffuse midline glioma: Increasing the drug-tumor residence time

Neuro-Oncology Advances(2023)10.1093/noajnl/vdad033

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5 citations

Julian S. Rechberger, Liang Zhang, Ju‐Hee Oh, Jacob B. Anderson, Cody L. Nesvick +5 more

Central Nervous System Distribution of Panobinostat in Preclinical Models to Guide Dosing for Pediatric Brain Tumors

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.123.001826

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4 citations

Ju‐Hee Oh, Wenjuan Zhang, Sneha Rathi, Jon D. Larson, Robert J. Wechsler‐Reya +3 more

WSD-0922, a novel brain-penetrant inhibitor of epidermal growth factor receptor, promotes survival in glioblastoma mouse models

Neuro-Oncology Advances(2023)10.1093/noajnl/vdad066

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5 citations

Sylwia A. Stopka, Ju‐Hee Oh, Ann C. Mladek, Danielle M. Burgenske, Michael S. Regan +15 more

Bystander Effects, Pharmacokinetics, and Linker-Payload Stability of EGFR-Targeting Antibody-Drug Conjugates Losatuxizumab Vedotin and Depatux-M in Glioblastoma Models

Clinical Cancer Research(2024)10.1158/1078-0432.ccr-24-0426

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30 citations

Jessica I. Griffith, Kendra A. Porath, Sneha Rathi, Jiayan Le, Tugce I. Pasa +14 more

DNA-PK Inhibition Shows Differential Radiosensitization in Orthotopic GBM PDX Models Based on DDR Pathway Deficits

Molecular Cancer Therapeutics(2024)10.1158/1535-7163.mct-24-0003

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12 citations

Emily J. Smith, Michael S. Regan, Sylwia A. Stopka, Gerard Baquer, Zhiyi Xue +19 more

Differential Distribution of the DNA-PKcs Inhibitor Peposertib Selectively Radiosensitizes Patient-derived Melanoma Brain Metastasis Xenografts

Molecular Cancer Therapeutics(2024)10.1158/1535-7163.mct-23-0552

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12 citations

Sonja Dragojevic, Cameron M. Callaghan, Emily J. Smith, Surabhi Talele, Wenjuan Zhang +15 more

Central nervous system distributional kinetics of selected histone deacetylase inhibitors

Journal of Pharmacology and Experimental Therapeutics(2024)10.1124/jpet.124.002170

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6 citations

Ju‐Hee Oh, Wenjuan Zhang, Courtney C. Aldrich, Rachael W. Sirianni, William F. Elmquist +1 more

Modeling the Acute Mucosal Toxicity of Fractionated Radiotherapy Combined with the ATM Inhibitor WSD0628

Molecular Cancer Therapeutics(2024)10.1158/1535-7163.mct-24-0664

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4 citations

Sneha Rathi, Margaret A. Connors, Michael P. Grams, Rachael A. Vaubel, Katrina K. Bakken +13 more

Pharmacokinetics of Panobinostat: Interspecies Difference in Metabolic Stability

Journal of Pharmacology and Experimental Therapeutics(2024)10.1124/jpet.123.002051

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2 citations

Ju‐Hee Oh, Wenjuan Zhang, Courtney C. Aldrich, Rachael W. Sirianni, William F. Elmquist +1 more

The novel brain penetrant ataxia-telangiectasia mutated inhibitor WSD0628 provides robust radiosensitization of brain tumor patient-derived xenografts

Neuro-Oncology(2025)10.1093/neuonc/noaf102

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7 citations

Ann C. Mladek, Sneha Rathi, Sonia Jain, Rachael A. Vaubel, Lateef A Odukoya +17 more

PK-PD-efficacy modeling of brigimadlin in MDM2-amplified glioblastoma.

Journal of Clinical Oncology(2024)10.1200/jco.2024.42.16_suppl.2071

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0 citations

Wenjuan Zhang, Danielle M. Burgenske, Katie L. Waller, Paul A. Decker, Matt Kosel +13 more

Pre-clinical modeling of navtemadlin pharmacokinetics (PK), pharmacodynamics (PD), and efficacy in glioblastoma, IDH-wildtype.

Journal of Clinical Oncology(2024)10.1200/jco.2024.42.16_suppl.2012

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0DataRank · unranked

0 citations

Wenjuan Zhang, Ann C. Mladek, Tugce I. Pasa, Katie L. Waller, Sylwia A. Stopka +15 more

Factors Influencing the Central Nervous System (CNS) Distribution of the Ataxia Telangiectasia Mutated and Rad3-Related Inhibitor Elimusertib (BAY1895344): Implications for the Treatment of CNS Tumors

Journal of Pharmacology and Experimental Therapeutics(2024)10.1124/jpet.123.002002

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0DataRank · unranked

0 citations

Ann C. Mladek, Ju‐Hee Oh, Sonja Dragojevic, Danielle M. Burgenske, Wenjuan Zhang +10 more

The impact of therapeutic radiation on drug distribution across the blood-brain barrier in normal mouse brain and orthotopic glioblastoma tumors

Neuro-Oncology(2025)10.1093/neuonc/noaf093

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4 citations

Michael P. Grams, Rajneet K. Oberoi, Ju‐Hee Oh, Paul A. Decker, Terence T. Sio +12 more

Preclinical Modeling of Navtemadlin Pharmacokinetics, Pharmacodynamics, and Efficacy in IDH–Wild-type Glioblastoma

Clinical Cancer Research(2025)10.1158/1078-0432.ccr-25-0244

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2 citations

Wenjuan Zhang, Ju-Hee Oh, Ann C. Mladek, Tugce I. Pasa, Jennifer Gantchev +24 more

Enhancing Brain Retention of a KIF11 Inhibitor Significantly Improves its Efficacy in a Mouse Model of Glioblastoma

Scientific Reports(2020)10.1038/s41598-020-63494-7

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28 citations

Rajappa S. Kenchappa, Afroz S. Mohammad, Karen E. Parrish, Minjee Kim, James F. Crish +7 more

Pharmacokinetic-pharmacodynamic-efficacy modeling of the MDM2 inhibitor brigimadlin in glioblastoma patient-derived xenografts

Neuro-Oncology Advances(2025)10.1093/noajnl/vdaf259

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0DataRank · unranked

0 citations

Wenjuan Zhang, Nishika Karbhari, Ju-Hee Oh, Katie L. Waller, Ann C. Mladek +16 more