🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Benoı̂t Laleu

Medicines for Malaria Venture

ORCID: 0000-0002-7530-2113
MedicineComputer ScienceMaterials Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile
0Author DataRank

Indexed papers

0in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 13 papers. Top paper: “Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series”.

Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00173
N/A
0DataRank · unranked
47 citations

Xiaoyi Deng, Shawn Watts, Goran Krilov, Aleksey I. Gerasyuto, Sreekanth Kokkonda +39 more

The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance

Cell chemical biology(2021)10.1016/j.chembiol.2021.06.006
N/A
0DataRank · unranked
30 citations

Ioanna Deni, Charisse Flerida A. Pasaje, John Okombo, Jessica L. Bridgford, Nina F. Gnädig +28 more

Piperidine-4-Carboxamides Target DNA Gyrase in Mycobacterium abscessus

Antimicrobial Agents and Chemotherapy(2021)10.1128/aac.00676-21
N/A
0DataRank · unranked
29 citations

Andreas Beuchel, Abdeldjalil Madani, Nadine Álvarez, Chao Chen, Wassihun Wedajo Aragaw +7 more

A fast-killing tyrosine amide (( S )-SW228703) with blood and liver-stage antimalarial activity associated with the Cyclic Amine Resistance Locus ( Pf CARL)

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.16.512381
N/A
0DataRank · unranked
0 citations

Aloysus K. Lawong, Suraksha Gahalawat, Ashwani Kumar, Chao Xing, Nimisha Mittal +12 more

Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation

Nature Communications(2023)10.1038/s41467-023-36921-2
N/A
0DataRank · unranked
31 citations

Charisse Flerida A. Pasaje, Robert L. Summers, Pamela Magistrado-Coxen, Kyra A. Schindler, Victoriano Corpas‐López +25 more

Fast-Killing Tyrosine Amide (( S )-SW228703) with Blood- and Liver-Stage Antimalarial Activity Associated with the Cyclic Amine Resistance Locus ( Pf CARL)

ACS Infectious Diseases(2023)10.1021/acsinfecdis.2c00527
N/A
0DataRank · unranked
10 citations

Aloysus K. Lawong, Suraksha Gahalawat, Ashwani Kumar, Chao Xing, Nimisha Mittal +12 more

Oxidative stress changes the effectiveness of artemisinin in Plasmodium falciparum

mBio(2024)10.1128/mbio.03169-23
N/A
0DataRank · unranked
19 citations

Debora Cassandra, Shulin Xu, Benoı̂t Laleu, Jeremy N. Burrows, John H. Adams +1 more

Structure-Based Discovery and Development of Highly Potent Dihydroorotate Dehydrogenase Inhibitors for Malaria Chemoprevention

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c02394
N/A
0DataRank · unranked
11 citations

Roger V. Bonnert, Jet Tsien, Xiaoyi Deng, Chris Higgs, Farah El Mazouni +39 more

Identification of potent and reversible piperidine carboxamides that are species-selective orally active proteasome inhibitors to treat malaria

Cell chemical biology(2024)10.1016/j.chembiol.2024.07.001
N/A
0DataRank · unranked
15 citations

Suraksha Gahalawat, S. Ray, Nhi Ho, Yan Han, Kurt E. Ward +29 more

Identification of α-Azacyclic Acetamide-Based Inhibitors of P. falciparum Na + Pump ( Pf ATP4) with Fast-Killing Asexual Blood-Stage Antimalarial Activity by Phenotypic Screening

ACS Infectious Diseases(2025)10.1021/acsinfecdis.5c00436
N/A
0DataRank · unranked
3 citations

Leah S. Imlay, Vandana Thathy, Kate J. Fairhurst, Adele M. Lehane, Aloysus K. Lawong +13 more

Identification of α-azacyclic acetamide-based inhibitors of P. falciparum Na + pump ( Pf ATP4) with fast-killing asexual blood-stage antimalarial activity by phenotypic screening

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.20.655166
N/A
0DataRank · unranked
0 citations

Leah S. Imlay, Vandana Thathy, Kate J. Fairhurst, Adele M. Lehane, Aloysus K. Lawong +13 more

Optimization of species-selective reversible proteasome inhibitors for the treatment of malaria

ChemRxiv(2025)10.26434/chemrxiv-2025-f64v2
N/A
0DataRank · unranked
0 citations

S. Ray, Xiaoyu Zhang, Xiaoyi Deng, Yan Han, Aloysus K. Lawong +21 more

Optimization of species-selective reversible proteasome inhibitors for the treatment of malaria

ChemRxiv(2025)10.26434/chemrxiv-2025-f64v2-v2
N/A
0DataRank · unranked
0 citations

S. Ray, Xiaoyu Zhang, Xiaoyi Deng, Yan Han, Zhe Chen +22 more