David C. Wedge

Also affiliated with Manchester University NHS Foundation Trust, Cancer Research UK Manchester Institute, NIHR Manchester Biomedical Research Centre, Manchester University

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

12.7Author DataRank

Indexed papers

6in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 6 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Pan-cancer analysis of whole genomes

Nature(2020)10.1038/s41586-020-1969-6

Top 3%

5.9DataRank

Top 3%3307 citations

Lauri A. Aaltonen, Federico Abascal, Adam Abeshouse, Hiroyuki Aburatani, David J. Adams +1244 more

Papers

Driven by 33 papers — median percentile 68. Top paper: “Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes”.

Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

Cell(2021)10.1016/j.cell.2021.03.009

N/A

7.3DataRank · unranked

560 citations

Ignaty Leshchiner, Kerstin Haase, Maxime Tarabichi, Jeff Wintersinger, Amit G. Deshwar +64 more

Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

Nature Genetics(2020)10.1038/s41588-019-0562-0

N/A

7.0DataRank · unranked

483 citations

Eva G. Alvarez, Adrian Baez‐Ortega, Jorge Zamora, Fran Supek, Jonas Demeulemeester +80 more

Pan-cancer analysis of whole genomes

Nature(2020)10.1038/s41586-020-1969-6

Top 3%

5.9DataRank

Top 3%3307 citations

Lauri A. Aaltonen, Federico Abascal, Adam Abeshouse, Hiroyuki Aburatani, David J. Adams +1244 more

Genomic and evolutionary classification of lung cancer in never smokers

Nature Genetics(2021)10.1038/s41588-021-00920-0

N/A

5.4DataRank · unranked

248 citations

Philippe Joubert, Naser Ansari‐Pour, Zhao Wei, Phuc H. Hoang, Rachel Lokanga +56 more

Uncovering novel mutational signatures by de novo extraction with SigProfilerExtractor

Cell Genomics(2022)10.1016/j.xgen.2022.100179

N/A

4.8DataRank · unranked

366 citations

Marcos Díaz‐Gay, Yang Wu, Mark Barnes, Raviteja Vangara, Erik N. Bergstrom +30 more

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes

Nature(2020)10.1038/s41586-020-1965-x

Top 5%

4.6DataRank

Top 5%668 citations

Federico Abascal, Jeremiah A. Wala, Ofer Shapira, Grace Tiao, Henrik Hornshøj +1240 more

A community effort to create standards for evaluating tumor subclonal reconstruction

Nature Biotechnology(2020)10.1038/s41587-019-0364-z

N/A

2.8DataRank · unranked

100 citations

Adriana Salcedo, Maxime Tarabichi, Shadrielle M. G. Espiritu, Amit G. Deshwar, Matei David +28 more

Germline MBD4 deficiency causes a multi-tumor predisposition syndrome

The American Journal of Human Genetics(2022)10.1016/j.ajhg.2022.03.018

N/A

1.9DataRank · unranked

79 citations

Hannah D. West, Edward Chew, Sara Galavotti, Christoffer Flensburg, Judith E. Grolleman +64 more

Germline determinants of the somatic mutation landscape in 2,642 cancer genomes

bioRxiv (Cold Spring Harbor Laboratory)(2017)10.1101/208330

Top 17%

1.2DataRank

Top 17%26 citations

Grace Tiao, Bin Zhu, Tobias Rausch, Francesc Muyas, Alan J. Robertson +108 more

Genetic and epigenetic intratumor heterogeneity impacts prognosis of lung adenocarcinoma

Nature Communications(2020)10.1038/s41467-020-16295-5

N/A

0.738DataRank · unranked

136 citations

Zhao Wei, Angela Cecilia Pesatori, Dario Consonni, Neil E. Caporaso, Tongwu Zhang +10 more

Genomic evolution shapes prostate cancer disease type

Cell Genomics(2024)10.1016/j.xgen.2024.100511

N/A

0.613DataRank · unranked

16 citations

Atef Sahli, Ruxandra Teslo, Vinayak Bhandari, Andreas Gruber, Aleksandra Ziubroniewicz +31 more

Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction

Nature Biotechnology(2024)10.1038/s41587-024-02250-y

Top 46%

0.396DataRank

Top 46%13 citations

Maxime Tarabichi, Alex Buchanan, Shadrielle M. G. Espiritu, Hongjiu Zhang, Kaiyi Zhu +83 more

Whole genome sequencing of 2,023 colorectal cancers reveals mutational landscapes, new driver genes and immune interactions

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.16.515599

Top 50%

0.353DataRank

Top 50%9 citations

Andreas Gruber, Ben Kinnersley, Daniel Chubb, Anna Frangou, Giulio Caravagna +29 more

Microbiome analysis of 940 lung cancers in never-smokers reveals lack of clinically relevant associations

Nature Communications(2025)10.1038/s41467-025-66780-y

Top 61%

0.241DataRank

Top 61%4 citations

Tongwu Zhang, Zhao Wei, Phuc H. Hoang, Samuel Anyaso‐Samuel, Jian Sang +57 more

Author Correction: Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

Communications Biology(2022)10.1038/s42003-022-03769-z

N/A

0.165DataRank · unranked

2 citations

Lars Feuerbach, Chen Hong, David Mas-Ponte, Randi Istrup Pedersen, PCAWG Drivers and Functional Interpretation Group +1255 more

Crowd-sourced benchmarking of single-sample tumour subclonal reconstruction

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.14.495937

N/A

0.104DataRank · unranked

1 citations

Maxime Tarabichi, Alex Buchanan, Shadrielle M. G. Espiritu, Hongjiu Zhang, Kaiyi Zhu +24 more

Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.28.359240

N/A

0DataRank · unranked

2 citations

Yonglan Zheng, Jason J. Pitt, Stefan C. Dentro, Toshio F. Yoshimatsu, Ayodele Sanni +21 more

The genomic and epigenomic evolutionary history of papillary renal cell carcinomas

Nature Communications(2020)10.1038/s41467-020-16546-5

N/A

0DataRank · unranked

37 citations

Maria Luana Poeta, Manuela Costantini, Tongwu Zhang, Jianxin Shi, Steno Sentinelli +21 more

Whole genome sequencing of 2,023 colorectal cancers reveals mutational landscapes, new driver genes and immune interactions

Research Square(2022)10.21203/rs.3.rs-2273265/v1

N/A

0DataRank · unranked

3 citations

Alex J. Cornish, Andreas Gruber, Richard S. Houlston, Amit Sud, Philip Law +29 more

Chromothripsis orchestrates leukemic transformation in blast phase MPN through targetable amplification of DYRK1A

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.08.570880

N/A

0DataRank · unranked

4 citations

BH Yip, Giulia Orlando, Hemant Goyal, Simeng Wen, Jing Wen +27 more

The genomic landscape of 2,023 colorectal cancers

Nature(2024)10.1038/s41586-024-07747-9

N/A

0DataRank · unranked

158 citations

Andreas Gruber, Ben Kinnersley, Daniel Chubb, Anna Frangou, Giulio Caravagna +31 more

Tracing Lung Cancer Risk Factors Through Mutational Signatures in Never-Smokers

American Journal of Epidemiology(2020)10.1093/aje/kwaa234

N/A

0DataRank · unranked

42 citations

Naoise C. Synnott, Jennifer Rosenbaum, Tongwu Zhang, Bin Zhu, Jianxin Shi +17 more

Prostate cancer evolution from multilineage primary to single lineage metastases with implications for liquid biopsy

Nature Communications(2020)10.1038/s41467-020-18843-5

N/A

0DataRank · unranked

79 citations

Е. В. Рябченко, Sinja Taavitsainen, Matti Kankainen, Gunes Gundem, Daniel Brewer +13 more

Genomes and epigenomes of matched normal and tumor breast tissue reveal diverse evolutionary trajectories and tumor-host interactions

The American Journal of Human Genetics(2024)10.1016/j.ajhg.2024.10.005

N/A

0DataRank · unranked

4 citations

Avraam Tapinos, Hela Koka, Priscilla Ming Yi Lee, Tongwu Zhang, Wei Zhu +21 more

APOBEC shapes tumor evolution and age at onset of lung cancer in smokers

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.02.587805

N/A

0DataRank · unranked

5 citations

Jian Sang, Phuc H. Hoang, Wei Zhao, Jennifer Rosenbaum, Kofi Ennu Johnson +26 more

The mutagenic forces shaping the genomes of lung cancer in never smokers

Nature(2025)10.1038/s41586-025-09219-0

N/A

0DataRank · unranked

43 citations

Tongwu Zhang, Phuc H. Hoang, Charles Leduc, Marina K. Baine, William D. Travis +64 more

Pathogenic variants reveal candidate genes for prostate cancer germline testing for men of African ancestry

Nature Communications(2025)10.1038/s41467-025-63865-6

N/A

0DataRank · unranked

11 citations

Pamela X. Y. Soh, Jue Jiang, Tumisang M. N. Mbeki, Melanie Louw, Daniel Burns +84 more

Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast-phase MPN through targetable overexpression of DYRK1A

Nature Genetics(2025)10.1038/s41588-025-02190-6

N/A

0DataRank · unranked

9 citations

Bon Ham Yip, Giulia Orlando, Jeremy Q. Wen, Sean Wen, Harsh Goyal +36 more

APOBEC affects tumor evolution and age at onset of lung cancer in smokers

Nature Communications(2025)10.1038/s41467-025-59923-8

N/A

0DataRank · unranked

9 citations

Jian Sang, Phuc H. Hoang, Zhao Wei, Jennifer Rosenbaum, Kofi Ennu Johnson +26 more

Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower

Nature Communications(2022)10.1038/s41467-022-32343-8

N/A

0DataRank · unranked

0 citations

PCAWG Drivers and Functional Interpretation Working Group, Federico Abascal, Samirkumar B. Amin, Pratiti Bandopadhayay, Rameen Beroukhim +1242 more

Causes of evolutionary divergence in prostate cancer.

PubMed(2025)10.48550/arxiv.2503.13189

N/A

0DataRank · unranked

0 citations

Atef Sahli, Valeriia Haberland, Aleksandra Ziuboniewicz, Christopher L. Wirth, G. Steven Bova +50 more

Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes

Nature Communications(2021)10.1038/s41467-021-27079-w

N/A

0DataRank · unranked

67 citations

Yonglan Zheng, Toshio F. Yoshimatsu, Ayodele Sanni, Mustapha Ajani, J.-P. de Reynier +23 more

Revealing the Drivers Underlying Distinct Evolutionary Trajectories in Lung Adenocarcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.64898/2025.12.19.695410

N/A

0DataRank · unranked

0 citations

Tongwu Zhang, Marcos Díaz-Gay, Christopher D. Steele, Phuc H. Hoang, Yang Yang +56 more

David C. Wedge

Indexed papers

Top data-sharing exemplar

Papers