Eytan Ruppin

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 5%percentile

0.500Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Synthetic lethality-based prediction of anti-SARS-CoV-2 targets

iScience(2022)10.1016/j.isci.2022.104311

Top 38%

0.500DataRank

Top 38%10 citations

Kuoyuan Cheng, Nishanth Ulhas Nair, Laura Martin‐Sancho, Sanju Sinha, Yuan Pu +7 more

Papers

Driven by 119 papers — median percentile 31. Top paper: “Identification of bacteria-derived HLA-bound peptides in melanoma”.

Identification of bacteria-derived HLA-bound peptides in melanoma

Nature(2021)10.1038/s41586-021-03368-8

N/A

7.4DataRank · unranked

444 citations

Adi Nagler, Deborah Nejman, Michal Alon, Chaya Barbolin, Eilon Barnea +48 more

Evolution of delayed resistance to immunotherapy in a melanoma responder

Nature Medicine(2021)10.1038/s41591-021-01331-8

N/A

3.6DataRank · unranked

137 citations

Jia‐Ren Lin, Emily Robitschek, Gyulnara G. Kasumova, Alex Heyde, Alvin Shi +35 more

Predicting tissue-specific gene expression from whole blood transcriptome

Science Advances(2021)10.1126/sciadv.abd6991

N/A

2.6DataRank · unranked

92 citations

Kun Wang, Eytan Ruppin, Sridhar Hannenhalli, Mahashweta Basu

In vitro and in vivo identification of clinically approved drugs that modify ACE2 expression

Molecular Systems Biology(2020)10.15252/msb.20209628

N/A

2.3DataRank · unranked

59 citations

Kuoyuan Cheng, Alejandro A. Schäffer, Kenneth Aldape, Eyal Schiff, Eytan Ruppin +1 more

Genome‐scale metabolic modeling reveals SARS‐CoV‐2‐induced metabolic changes and antiviral targets

Molecular Systems Biology(2021)10.15252/msb.202110260

N/A

1.3DataRank · unranked

49 citations

Laura Martin‐Sancho, Lipika R. Pal, Yuan Pu, Laura Riva, Xin Yin +5 more

Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

Nature(2020)10.1038/s41586-020-2577-1

N/A

1.0DataRank · unranked

858 citations

Shuofeng Yuan, Xin Yin, Laura Martin‐Sancho, Naoko Matsunaga, Lars Pache +40 more

Large-scale study of antibody titer decay following BNT162b2 mRNA vaccine or SARS-CoV-2 infection

medRxiv(2021)10.1101/2021.08.19.21262111

N/A

0.721DataRank · unranked

121 citations

Yotam Shenhar, Ilan Green, Eugene Merzon, Avivit Golan‐Cohen, Alejandro A. Schäffer +4 more

LORIS robustly predicts patient outcomes with immune checkpoint blockade therapy using common clinical, pathologic and genomic features

Nature Cancer(2024)10.1038/s43018-024-00772-7

N/A

0.712DataRank · unranked

114 citations

Yingying Cao, Hannah J. Sfreddo, Saugato Rahman Dhruba, Se‐Hoon Lee, Cristina Valero +5 more

Impact of the methylation classifier and ancillary methods on CNS tumor diagnostics

Neuro-Oncology(2021)10.1093/neuonc/noab227

N/A

0.704DataRank · unranked

108 citations

Zied Abdullaev, Drew Pratt, Hye‐Jung Chung, Shannon Skarshaug, Valerie Zgonc +25 more

Comparative Evaluation of LLMs in Clinical Oncology

NEJM AI(2024)10.1056/aioa2300151

N/A

0.694DataRank · unranked

101 citations

Deepak Dinakaran, Shuang G. Zhao, Eytan Ruppin, Barış Türkbey, Deborah E. Citrin +2 more

Transcriptomic Profiling of Plasma Extracellular Vesicles Enables Reliable Annotation of the Cancer-Specific Transcriptome and Molecular Subtype

Cancer Research(2024)10.1158/0008-5472.can-23-4070

N/A

0.692DataRank · unranked

21 citations

Jaewon J. Lee, Vittorio Branchi, Kimal Rajapakshe, Zhichao Xu, Naishu Kui +13 more

Reply to: ‘IMPRES does not reproducibly predict response to immune checkpoint blockade therapy in metastatic melanoma’

Nature Medicine(2019)10.1038/s41591-019-0646-5

N/A

0.685DataRank · unranked

11 citations

Joo Sang Lee, Eytan Ruppin, Noam Auslander

A landscape of response to drug combinations in non-small cell lung cancer

Nature Communications(2023)10.1038/s41467-023-39528-9

N/A

0.604DataRank · unranked

55 citations

Patricia Greninger, Xiaohu Zhang, Adam Friedman, Arnaud Amzallag, Eliane Cortez +25 more

The landscape of receptor-mediated precision cancer combination therapy via a single-cell perspective

Nature Communications(2022)10.1038/s41467-022-29154-2

N/A

0.550DataRank · unranked

38 citations

Pattara Sukprasert, Rahulsimham Vegesna, Sanju Sinha, Fiorella Schischlik, Natalie Artzi +4 more

A machine learning model reveals expansive downregulation of ligand-receptor interactions that enhance lymphocyte infiltration in melanoma with developed resistance to immune checkpoint blockade

Nature Communications(2024)10.1038/s41467-024-52555-4

N/A

0.540DataRank · unranked

14 citations

Binbin Wang, Di Wu, Saugato Rahman Dhruba, Matthew Nagy, Sushant Patkar +5 more

Synthetic lethality-based prediction of anti-SARS-CoV-2 targets

iScience(2022)10.1016/j.isci.2022.104311

Top 38%

0.500DataRank

Top 38%10 citations

Kuoyuan Cheng, Nishanth Ulhas Nair, Laura Martin‐Sancho, Sanju Sinha, Yuan Pu +7 more

Genomic and transcriptomic analyses identify a prognostic gene signature and predict response to therapy in pleural and peritoneal mesothelioma

Cell Reports Medicine(2023)10.1016/j.xcrm.2023.100938

N/A

0.500DataRank · unranked

27 citations

Qun Jiang, Jun S. Wei, Vikram Misra, Betsy Morrow, Chimene Kesserwan +11 more

Loss of tumor suppressors promotes inflammatory tumor microenvironment and enhances LAG3+T cell mediated immune suppression

Nature Communications(2024)10.1038/s41467-024-50262-8

N/A

0.464DataRank · unranked

21 citations

Zhiguang Xiao, Jae Young So, Abdul Ahad, Selina Montoya, Woo Yong Park +15 more

Single-cell methylation sequencing data reveal succinct metastatic migration histories and tumor progression models

Genome Research(2023)10.1101/gr.277608.122

N/A

0.373DataRank · unranked

11 citations

Xuan Cindy Li, Farid Rashidi Mehrabadi, Alejandro A. Schäffer, Drew Pratt, David R. Crawford +8 more

Prediction of cancer treatment response from histopathology images through imputed transcriptomics.

Journal of Clinical Oncology(2023)10.1200/jco.2023.41.16_suppl.1551

N/A

0.292DataRank · unranked

6 citations

Gal Dinstag, Leandro C. Hermida, Doreen S. Ben-Zvi, Chani Stossel, Tejas Patil +15 more

Reusability report: Leveraging supervised learning to uncover phenotype-relevant biology from single-cell RNA sequencing data

Nature Machine Intelligence(2024)10.1038/s42256-024-00804-y

N/A

0.241DataRank · unranked

4 citations

Tiangen Chang, Sahil Sahni, Eytan Ruppin, Yingying Cao

Chromosome 7 to the rescue: overcoming chromosome 10 loss in gliomas

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.17.576103

N/A

0.208DataRank · unranked

3 citations

Alejandro A. Schäffer, Michael Gertz, Kuoyuan Cheng, Johanna Zerbib, Avinash Sahu +6 more

Fraction of copy-number alterations significantly predicts survival following immunotherapy in a few cancers

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.28.522101

N/A

0.208DataRank · unranked

3 citations

Yingying Cao, Eldad D. Shulman, Alejandro A. Schäffer, Eytan Ruppin, Tiangen Chang

Predicting patient treatment response and resistance via single-cell transcriptomics of their tumors

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.11.475728

N/A

0.208DataRank · unranked

3 citations

Rahulsimham Vegesna, Saugato Rahman Dhruba, Wei Wu, D. Lucas Kerr, Oleg V. Stroganov +9 more

Single-cell methylation sequencing data reveal succinct metastatic migration histories and tumor progression models

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.22.436475

N/A

0.165DataRank · unranked

2 citations

Xuan Cindy Li, Farid Rashidi Mehrabadi, Alejandro A. Schäffer, Drew Pratt, David R. Crawford +8 more

Cross-Species Analysis of Protein-protein Interaction Networks

Computational Biology(2008)10.1007/978-1-84800-125-1_9

N/A

0.133DataRank · unranked

1 citations

Eytan Ruppin, Roded Sharan, Nir Yosef

Supplementary Figure from AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer

(2023)10.1158/2159-8290.22541643

N/A

0.128DataRank · unranked

1 citations

Nishanth Belugali Nataraj, Joo Sang Lee, Benny Zhitomirsky, Yaara Oren, Sara Oster Flayshman +34 more

Cross-species identification of cancer-resistance associated genes uncovers their relevance to human cancer risk

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.19.444895

N/A

0.104DataRank · unranked

1 citations

Kuoyuan Cheng, Lamis Naddaf, Elad Sharon, Lipika R. Pal, Padma Sheila Rajagopal +7 more

Phylogenetic analysis of longitudinal melanoma samples to reveal convergent evolution and markers of immunotherapy resistance.

Journal of Clinical Oncology(2018)10.1200/jco.2018.36.15_suppl.9581

N/A

0.104DataRank · unranked

1 citations

Gao Zhang, Alvin Shi, Benjamin Izar, Alexander Heyde, Gyulnara G. Kasumova +14 more

The tumour microenvironment shapes innate lymphoid cells in patients with hepatocellular carcinoma

Gut(2021)10.1136/gutjnl-2021-325288

N/A

0DataRank · unranked

116 citations

E. Michael Gertz, Alejandro A. Schäffer, Amanda J. Craig, Benjamin Ruf, Varun Subramanyam +22 more

Synthetic lethality-mediated precision oncology via the tumor transcriptome

Cell(2021)10.1016/j.cell.2021.03.030

N/A

0DataRank · unranked

159 citations

Nishanth Ulhas Nair, Gal Dinstag, Lesley M. Chapman, Youngmin Chung, Kun Wang +18 more

Serine Biosynthesis Is a Metabolic Vulnerability in IDH2-Driven Breast Cancer Progression

Cancer Research(2021)10.1158/0008-5472.can-19-3020

N/A

0DataRank · unranked

55 citations

Joo Sang Lee, Tamar Shami, Michal Harel, Lir Beck, Michael Selitrennik +5 more

Elapsed time since BNT162b2 vaccine and risk of SARS-CoV-2 infection: test negative design study

BMJ(2021)10.1136/bmj-2021-067873

N/A

0DataRank · unranked

167 citations

Eugene Merzon, Alejandro A. Schäffer, Yotam Shenhar, Ilan Green, Avivit Golan‐Cohen +4 more

A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing

Nature Communications(2021)10.1038/s41467-021-26788-6

N/A

0DataRank · unranked

47 citations

Karina Barbosa, Kuoyuan Cheng, Mark D.M. Leiserson, Prashant Jain, Anagha Deshpande +8 more

Cysteine and Folate Metabolism Are Targetable Vulnerabilities of Metastatic Colorectal Cancer

Cancers(2021)10.3390/cancers13030425

N/A

0DataRank · unranked

25 citations

Carles Foguet, Míriam Tarrado‐Castellarnau, Silvia Marín, Xavier Hernandez‐Alias, Jordi Perarnau +8 more

Integration of adeno-associated virus (AAV) into the genomes of most Thai and Mongolian liver cancer patients does not induce oncogenesis

BMC Genomics(2021)10.1186/s12864-021-08098-9

N/A

0DataRank · unranked

24 citations

Dana A. Dominguez, Lesley M. Chapman, E. Michael Gertz, Anuradha Budhu, Marshonna Forgues +10 more

A Transcriptionally Distinct Subpopulation of Healthy Acinar Cells Exhibit Features of Pancreatic Progenitors and PDAC

Cancer Research(2021)10.1158/0008-5472.can-21-0427

N/A

0DataRank · unranked

18 citations

Arashdeep Singh, Farid Rashidi Mehrabadi, Li Wang, Eytan Ruppin, H. Efsun Arda +2 more

Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma

Nature Communications(2021)10.1038/s41467-021-21804-1

N/A

0DataRank · unranked

243 citations

Joo Sang Lee, Chi Ma, Laurence P. Diggs, S. Heinrich, Ching-Wen Chang +9 more

Elapsed time since BNT162b2 vaccine and risk of SARS-CoV-2 infection in a large cohort

medRxiv(2021)10.1101/2021.08.03.21261496

N/A

0DataRank · unranked

72 citations

Eugene Merzon, Alejandro A. Schäffer, Yotam Shenhar, Ilan Green, Avivit Golan‐Cohen +4 more

Genome-scale metabolic modeling reveals SARS-CoV-2-induced metabolic changes and antiviral targets

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.27.428543

N/A

0DataRank · unranked

8 citations

Laura Martin-Sancho, Lipika R. Pal, Yuan Pu, Laura Riva, Xin Yin +5 more

A landscape of synergistic drug combinations in non-small-cell lung cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.03.447011

N/A

0DataRank · unranked

5 citations

Patricia Greninger, Adam Friedman, Arnaud Amzallag, Eliane Cortez, Avinash Sahu +16 more

Deconvolving clinically relevant cellular immune crosstalk from bulk gene expression using CODEFACS and LIRICS

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.20.427515

N/A

0DataRank · unranked

2 citations

Sushant Patkar, Joo Sang Lee, E. Michael Gertz, Welles Robinson, Fiorella Schischlik +4 more

Systematic investigation of cytokine signaling activity at the tissue and single-cell levels

Nature Methods(2021)10.1038/s41592-021-01274-5

N/A

0DataRank · unranked

261 citations

Yu Zhang, Beibei Ru, Yu-an Yang, Trang Vu, Rohit Paul +7 more

Using a recently approved tumor mutational burden biomarker to stratify patients for immunotherapy may introduce a sex bias

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.28.446208

N/A

0DataRank · unranked

2 citations

Sanju Sinha, Kuoyuan Cheng, Sanna Madan, Ayelet Erez, Bríd M. Ryan +4 more

A transcriptionally distinct subpopulation of healthy acinar cells exhibit features of pancreatic progenitors and PDAC

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.04.425042

N/A

0DataRank · unranked

1 citations

Arashdeep Singh, Farid Rashidi, Li Wang, Eytan Ruppin, Efsun Arda +2 more

Data from AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer

(2023)10.1158/2159-8290.c.6549711.v1

N/A

0DataRank · unranked

0 citations

Nishanth Belugali Nataraj, Joo Sang Lee, Benny Zhitomirsky, Yaara Oren, Sara Oster Flayshman +34 more

Sex biases in cancer and autoimmune disease incidence are strongly positively correlated with mitochondrial gene expression across human tissues

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.07.459207

N/A

0DataRank · unranked

1 citations

Sanju Sinha, Nishanth Ulhas Nair, Bríd M. Ryan, Jill S. Barnholtz‐Sloan, Stephen M. Mount +8 more

Pan-cancer analysis of patient tumor single-cell transcriptomes identifies promising selective and safe CAR targets in head and neck cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.29.462485

N/A

0DataRank · unranked

1 citations

Sanju Sinha, J. Silvio Gutkind, Ezra E.W. Cohen, Alejandro A. Schäffer, Eytan Ruppin +1 more

Synthetic lethality-based prediction of anti-SARS-CoV-2 targets

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.14.460408

N/A

0DataRank · unranked

0 citations

Kuoyuan Cheng, Nishanth Ulhas Nair, Laura Martin‐Sancho, Sanju Sinha, Yuan Pu +7 more

A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing

Research Square(2021)10.21203/rs.3.rs-199044/v1

N/A

0DataRank · unranked

0 citations

Karina Guerra, Kuoyuan Cheng, Mark D.M. Leiserson, Prashant Jain, Anagha Deshpande +8 more

Astrocyte immunometabolic regulation of the tumour microenvironment drives glioblastoma pathogenicity

Brain(2022)10.1093/brain/awac222

N/A

0DataRank · unranked

114 citations

Bar Philosof, Noga Budick-Harmelin, Tom Chernobylsky, A. Ron, Rotem Katzir +11 more

RETRACTED ARTICLE: Predicting cancer prognosis and drug response from the tumor microbiome

Nature Communications(2022)10.1038/s41467-022-30512-3

N/A

0DataRank · unranked

62 citations

E. Michael Gertz, Eytan Ruppin, Leandro C. Hermida

Deconvolving Clinically Relevant Cellular Immune Cross-talk from Bulk Gene Expression Using CODEFACS and LIRICS Stratifies Patients with Melanoma to Anti–PD-1 Therapy

Cancer Discovery(2022)10.1158/2159-8290.cd-21-0887

N/A

0DataRank · unranked

61 citations

Sushant Patkar, Joo Sang Lee, E. Michael Gertz, Welles Robinson, Fiorella Schischlik +4 more

Clinically oriented prediction of patient response to targeted and immunotherapies from the tumor transcriptome

Med(2022)10.1016/j.medj.2022.11.001

N/A

0DataRank · unranked

42 citations

Eldad D. Shulman, Efrat Elis, Doreen S. Ben-Zvi, Omer Tirosh, Eden Maimon +26 more

Predicting cancer prognosis and drug response from the tumor microbiome

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.21.214148

N/A

0DataRank · unranked

0 citations

E. Michael Gertz, Eytan Ruppin, Leandro C. Hermida

Immune Determinants of the Association between Tumor Mutational Burden and Immunotherapy Response across Cancer Types

Cancer Research(2022)10.1158/0008-5472.can-21-2542

N/A

0DataRank · unranked

43 citations

Sanju Sinha, Cristina Valero, Alejandro A. Schäffer, Kenneth Aldape, Kevin Litchfield +4 more

Race is a key determinant of the human intratumor microbiome

Cancer Cell(2022)10.1016/j.ccell.2022.08.007

N/A

0DataRank · unranked

34 citations

Yuan Liu, Leandro C. Hermida, E. Michael Gertz, Zhao Zhang, Qiang Li +4 more

MPAPASS software enables stitched multiplex, multidimensional EV repertoire analysis and a standard framework for reporting bead-based assays

Cell Reports Methods(2022)10.1016/j.crmeth.2021.100136

N/A

0DataRank · unranked

27 citations

Bryce Killingsworth, Julia Kepley, Tim Traynor, Sean Cook, Jason E. Savage +32 more

Strain level microbial detection and quantification with applications to single cell metagenomics

Nature Communications(2022)10.1038/s41467-022-33869-7

N/A

0DataRank · unranked

14 citations

Alejandro A. Schäffer, Welles Robinson, Junyan Xu, Eytan Ruppin, A. Funda Ergun +3 more

The Landscape of Receptor-Mediated Precision Cancer Combination Therapy: A Single-Cell Perspective

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.28.923532

N/A

0DataRank · unranked

0 citations

Pattara Sukprasert, Rahulsimham Vegesna, Sanju Sinha, Fiorella Schischlik, Natalie Artzi +4 more

Sex Biases in Cancer and Autoimmune Disease Incidence Are Strongly Positively Correlated with Mitochondrial Gene Expression across Human Tissues

Cancers(2022)10.3390/cancers14235885

N/A

0DataRank · unranked

2 citations

Sanju Sinha, Nishanth Ulhas Nair, Bríd M. Ryan, Jill S. Barnholtz‐Sloan, Stephen M. Mount +8 more

Prediction of cancer treatment response from histopathology images through imputed transcriptomics

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.07.495219

N/A

0DataRank · unranked

9 citations

Gal Dinstag, Leandro C. Hermida, Doreen S. Ben-Zvi, Efrat Elis, Katherine Caley +25 more

Predicting patient treatment response and resistance via single-cell transcriptomics of their tumors.

Journal of Clinical Oncology(2022)10.1200/jco.2022.40.16_suppl.e20540

N/A

0DataRank · unranked

5 citations

Rahulsimham Vegesna, Saugato Rahman Dhruba, Wei Wu, D. Lucas Kerr, Oleg V. Stroganov +9 more

Whole exome precision oncology targeting synthetic lethal vulnerabilities across the tumor transcriptome

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.16.951699

N/A

0DataRank · unranked

1 citations

Nishanth Ulhas Nair, Lesley M. Chapman, Sanju Sinha, Kun Wang, Houngui Cha +10 more

scRNA-seq analysis of colon and esophageal tumors uncovers abundant microbial reads in myeloid cells undergoing proinflammatory transcriptional alterations

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.14.096230

N/A

0DataRank · unranked

5 citations

Joshua K. Stone, Fiorella Schischlik, Billel Gasmi, Michael C. Kelly, Charlie Seibert +13 more

Predicting COVID-19 severity using major risk factors and received vaccines

medRxiv(2022)10.1101/2021.12.31.21268575

N/A

0DataRank · unranked

2 citations

Alejandro A. Schäffer, Eugene Merzon, Ilan Green, Eli Magen, Avivit Golan‐Cohen +3 more

Altered Gene Expression in Excitatory Neurons is Associated with Alzheimer’s Disease and Its Higher Incidence in Women

Research Square(2022)10.21203/rs.3.rs-1953485/v1

N/A

0DataRank · unranked

2 citations

Jielin Xu, Feixiong Cheng, Eytan Ruppin, Alejandro A. Schäffer, A. Xavier Garcia

Deep characterization of cancer drugs mechanism of action by integrating large-scale genetic and drug screens

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.17.512424

N/A

0DataRank · unranked

2 citations

Neelam Sinha, Eytan Ruppin, Sanju Sinha

Predicting patient treatment response and resistance via single-cell transcriptomics of their tumors

Research Square(2022)10.21203/rs.3.rs-1641376/v1

N/A

0DataRank · unranked

0 citations

Sanju Sinha, Rahulsimham Vegesna, Ashwin V. Kammula, Saugato Rahman Dhruba, Wei Wu +14 more

Identification of drugs associated with reduced severity of COVID-19: A case-control study in a large population

medRxiv(2020)10.1101/2020.10.13.20211953

N/A

0DataRank · unranked

21 citations

Alejandro A. Schäffer, Assi Cicurel, Ilan Feldhamer, Ameer Tal, Kuoyuan Cheng +5 more

Systematic Cell Line-Based Identification of Drugs Modifying ACE2 Expression

Preprints.org(2020)10.20944/preprints202003.0446.v1

N/A

0DataRank · unranked

23 citations

Kuoyuan Cheng, Kenneth Aldape, Eyal Schiff, Eytan Ruppin, Sanju Sinha

Optimizing cancer immunotherapy response prediction by tumor aneuploidy score and fraction of copy number alterations

npj Precision Oncology(2023)10.1038/s41698-023-00408-6

N/A

0DataRank · unranked

20 citations

Yingying Cao, Eldad D. Shulman, Uri Ben‐David, Alejandro A. Schäffer, Eytan Ruppin +1 more

Glucose-6-phosphate dehydrogenase deficiency and long-term risk of immune-related disorders

Frontiers in Immunology(2023)10.3389/fimmu.2023.1232560

N/A

0DataRank · unranked

18 citations

Alejandro A. Schäffer, Matitiahu Berkovitch, David Ozeri, Eugene Merzon, Ilan Green +5 more

Glucose-6-Phosphate Dehydrogenase Deficiency and Coronavirus Disease 2019

Clinical Infectious Diseases(2023)10.1093/cid/ciad348

N/A

0DataRank · unranked

13 citations

Matitiahu Berkovitch, Eugene Merzon, Avivit Golan‐Cohen, Ilan Green, Eytan Ruppin +3 more

Pan-Cancer Analysis of Patient Tumor Single-Cell Transcriptomes Identifies Promising Selective and Safe Chimeric Antigen Receptor Targets in Head and Neck Cancer

Cancers(2023)10.3390/cancers15194885

N/A

0DataRank · unranked

6 citations

Sanju Sinha, Tiangen Chang, J. Silvio Gutkind, Ezra E.W. Cohen, Alejandro A. Schäffer +2 more

Higher prevalence of homologous recombination deficiency in tumors from African Americans versus European Americans

Nature Cancer(2020)10.1038/s43018-019-0009-7

N/A

0DataRank · unranked

45 citations

Khadijah A. Mitchell, Adriana Zingone, Elise D. Bowman, Neelam Sinha, Alejandro A. Schäffer +4 more

Single-Cell–Derived Primary Rectal Carcinoma Cell Lines Reflect Intratumor Heterogeneity Associated with Treatment Response

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-19-1984

N/A

0DataRank · unranked

13 citations

Lena Anthuber, Daniela Hirsch, Darawalee Wangsa, Justin Lack, Nicole E. McNeil +17 more

Prediction of cancer treatment response from histopathology images through imputed transcriptomics

Research Square(2023)10.21203/rs.3.rs-3193270/v1

N/A

0DataRank · unranked

6 citations

Danh-Tai Hoang, Gal Dinstag, Leandro C. Hermida, Doreen S. Ben-Zvi, Efrat Elis +25 more

Predicting tumor immune microenvironment and checkpoint therapy response of head & neck cancer patients from blood immune single-cell transcriptomics

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.17.524455

N/A

0DataRank · unranked

4 citations

Tiangen Chang, Fiorella Schischlik, Kun Wang, Sanju Sinha, Sridhar Hannenhalli +3 more

Charting the transcriptomic landscape of primary and metastatic cancers in relation to their origin and target normal tissues

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.30.564810

N/A

0DataRank · unranked

4 citations

Camilo Calvo-Alcañiz, Padma Sheila Rajagopal, Stefano Scalera, Valeria Canu, Sanju Sinha +9 more

Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency and Long-Term Risk of Immune-Related diseases

medRxiv(2023)10.1101/2023.03.23.23287616

N/A

0DataRank · unranked

3 citations

Alejandro A. Schäffer, Matitiahu Berkovitch, David Ozeri, Eugene Merzon, Ilan Green +5 more

Deactivation of ligand-receptor interactions enhancing lymphocyte infiltration drives melanoma resistance to Immune Checkpoint Blockade

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.20.558683

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2 citations

Binbin Wang, Di Wu, Saugato Rahman Dhruba, Matthew Nagy, Sushant Patkar +4 more

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Research Square(2023)10.21203/rs.3.rs-2644875/v1

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1 citations

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bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.29.569032

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1 citations

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bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.17.524482

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0 citations

Kun Wang, Peng Jiang, Eytan Ruppin, Binbin Wang

Data from A Transcriptionally Distinct Subpopulation of Healthy Acinar Cells Exhibit Features of Pancreatic Progenitors and PDAC

(2023)10.1158/0008-5472.c.6512943.v1

Top 100%

0DataRank

Top 100%0 citations

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Robust prediction of patient outcomes with immune checkpoint blockade therapy for cancer using common clinical, pathologic, and genomic features

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.04.547697

N/A

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0 citations

Yingying Cao, Hannah J. Sfreddo, Saugato Rahman Dhruba, Se‐Hoon Lee, Cristina Valero +5 more

Robust prediction of patient outcomes with immune checkpoint blockade therapy for cancer using common clinical, pathologic, and genomic features

Research Square(2023)10.21203/rs.3.rs-3087126/v1

N/A

0DataRank · unranked

0 citations

Tiangen Chang, Yingying Cao, Hannah Sfreddo, Saugato Rahman Dhruba, Se‐Hoon Lee +5 more

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Nature Cancer(2024)10.1038/s43018-024-00793-2

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141 citations

Gal Dinstag, Eldad D. Shulman, Leandro C. Hermida, Doreen S. Ben-Zvi, Efrat Elis +26 more

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Cancer Research(2020)10.1158/0008-5472.can-19-1184

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50 citations

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Cancer Research(2020)10.1158/0008-5472.can-20-0125

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68 citations

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Nature Communications(2024)10.1038/s41467-024-46945-x

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58 citations

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Cancer Discovery(2024)10.1158/2159-8290.cd-23-0309

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36 citations

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Med(2024)10.1016/j.medj.2023.12.009

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32 citations

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npj Genomic Medicine(2024)10.1038/s41525-024-00397-w

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23 citations

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Annals of Oncology(2024)10.1016/j.annonc.2024.11.008

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22 citations

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Supplementary Figure from AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer

Figshare(2023)10.1158/2159-8290.22541643.v1

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0DataRank · unranked

0 citations

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Supplementary Data from AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer

(2023)10.1158/2159-8290.22541646

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0 citations

Nishanth Belugali Nataraj, Joo Sang Lee, Benny Zhitomirsky, Yaara Oren, Sara Oster Flayshman +34 more

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Cancer Research Communications(2024)10.1158/2767-9764.crc-24-0092

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10 citations

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18 citations

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Figshare(2023)10.1158/2159-8290.22541652.v1

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0DataRank · unranked

0 citations

Nishanth Belugali Nataraj, Joo Sang Lee, Benny Zhitomirsky, Yaara Oren, Sara Oster Flayshman +34 more

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Cancer Discovery(2024)10.1158/2159-8290.cd-23-1422

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12 citations

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10 citations

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iScience(2024)10.1016/j.isci.2024.109926

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0DataRank · unranked

2 citations

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Supplementary Data from AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer

Figshare(2023)10.1158/2159-8290.22541646.v1

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0 citations

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Microenvironment Shapes Small Cell Lung Cancer Neuroendocrine States and Presents Therapeutic Opportunities

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.09.579028

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6 citations

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Supplementary Data from AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer

(2023)10.1158/2159-8290.22541649

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0DataRank · unranked

0 citations

Nishanth Belugali Nataraj, Joo Sang Lee, Benny Zhitomirsky, Yaara Oren, Sara Oster Flayshman +34 more

Hallmarks of artificial intelligence contributions to precision oncology

Nature Cancer(2025)10.1038/s43018-025-00917-2

N/A

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55 citations

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Translation dysregulation in cancer as a source for targetable antigens

Cancer Cell(2025)10.1016/j.ccell.2025.03.003

N/A

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21 citations

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Longitudinal liquid biopsy identifies an early predictive biomarker of immune checkpoint blockade response in head and neck squamous cell carcinoma

Nature Communications(2025)10.1038/s41467-025-63538-4

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12 citations

Robert Saddawi‐Konefka, Lauren Clubb, Shiqi Tang, Di Wu, Sumit Mukherjee +11 more

Re-epithelialization of cancer cells increases autophagy and DNA damage: Implications for breast cancer dormancy and relapse

Science Signaling(2025)10.1126/scisignal.ado3473

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8 citations

Suvendu Giri, Rishita Chatterjee, Arturo Simoni-Nieves, Maha Abedrabbo, Alessandro Genna +37 more

Path2Omics Enhances Transcriptomic and Methylation Prediction Accuracy from Tumor Histopathology

Cancer Research(2025)10.1158/0008-5472.can-25-4350

N/A

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5 citations

Eldad D. Shulman, Saugato Rahman Dhruba, Nishanth Ulhas Nair, Ranjan Kumar Barman, Thomas Cantore +10 more

DeepTarget predicts anti-cancer mechanisms of action of small molecules by integrating drug and genetic screens

npj Precision Oncology(2025)10.1038/s41698-025-01111-4

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2 citations

Neelam Sinha, Marlenne Perales, Adi V Tarrab, Trinh Nguyen, Lihe Liu +16 more

Finding Multiple Optimal Solutions to an Integer Linear Program by Random Perturbations of Its Objective Function

Algorithms(2025)10.3390/a18030140

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2 citations

Pattara Sukprasert, Eytan Ruppin, Samir Khuller, Alejandro A. Schäffer, Noah Schulhof

Enhanced prediction of breast cancer patient response to chemotherapy by integrating deconvolved expression patterns of immune, stromal and tumor cells

Cancer Letters(2025)10.1016/j.canlet.2025.218101

N/A

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1 citations

Sahil Sahni, Binbin Wang, Di Wu, Padma Sheila Rajagopal, Yael Schmidt +7 more

Finding Multiple Optimal Solutions to an Integer Linear Program by Random Perturbations of its Objective Function

Preprints.org(2025)10.20944/preprints202501.1518.v1

N/A

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0 citations

Pattara Sukprasert, Eytan Ruppin, Samir Khuller, Alejandro A. Schäffer, Noah Schulhof

Pan-cancer prediction of tumor immune activation and response to immune checkpoint blockade from tumor transcriptomics and histopathology

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.27.661875

N/A

0DataRank · unranked

0 citations

Sumeet Patiyal, Lipika R. Pal, Tiangen Chang, Sumona Biswas, Saugato Rahman Dhruba +36 more

Supplementary Data from AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer

Figshare(2023)10.1158/2159-8290.22541649.v1

N/A

0DataRank · unranked

0 citations

Nishanth Belugali Nataraj, Joo Sang Lee, Benny Zhitomirsky, Yaara Oren, Sara Oster Flayshman +34 more

Data from AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer

(2023)10.1158/2159-8290.c.6549711

N/A

0DataRank · unranked

0 citations

Nishanth Belugali Nataraj, Joo Sang Lee, Benny Zhitomirsky, Yaara Oren, Sara Oster Flayshman +34 more

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