Xi Chen

Also affiliated with Shanxi University, Second People's Hospital of Yunnan Province, Jiangsu Cancer Hospital, Sunesis (United States)

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 38 papers. Top paper: “Sex-specific DNA methylation differences in Alzheimer’s disease pathology”.

Sex-specific DNA methylation differences in Alzheimer’s disease pathology

Acta Neuropathologica Communications(2021)10.1186/s40478-021-01177-8

N/A

1.4DataRank · unranked

70 citations

Juan I. Young, Lissette Gomez, Tiago C. Silva, Michael A. Schmidt, Jesse Cai +4 more

Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection

eLife(2021)10.7554/elife.69975

N/A

0.742DataRank · unranked

34 citations

Jingjing Yu, Longyong Xu, Katharine Umphred-Wilson, Fanglue Peng, Yao Ding +9 more

Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer

Cancer Cell(2020)10.1016/j.ccell.2020.02.003

N/A

0.702DataRank · unranked

107 citations

Meenakshi Anurag, Jonathan T. Lei, Jin Cao, Purba Singh, Jianheng Peng +26 more

Development of a RIPK1 degrader to enhance antitumor immunity

Nature Communications(2024)10.1038/s41467-024-55006-2

N/A

0.643DataRank · unranked

26 citations

Dong Lu, Xiaoli Qi, Rishi R. Paudel, Hanfeng Lin, Bryan L. Holloman +8 more

IRE1α silences dsRNA to prevent taxane-induced pyroptosis in triple-negative breast cancer

Cell(2024)10.1016/j.cell.2024.09.032

N/A

0.621DataRank · unranked

62 citations

Fanglue Peng, Qin Luo, Yao Ding, Fei Yuan, Liting Zheng +43 more

IRE1α–XBP1 safeguards hematopoietic stem and progenitor cells by restricting pro-leukemogenic gene programs

Nature Immunology(2025)10.1038/s41590-024-02063-w

N/A

0.500DataRank · unranked

17 citations

Francheska Son, Akanksha Verma, Saswat Kumar Bal, Qianzi Tang, Rui Wang +16 more

Endoplasmic Reticulum Stress in Bone Metastases

Frontiers in Oncology(2020)10.3389/fonc.2020.01100

N/A

0DataRank · unranked

6 citations

Weijie Zhang, Xiang H.-F. Zhang, Xi Chen, Longyong Xu

EglN2 associates with the NRF1‐PGC1α complex and controls mitochondrial function in breast cancer

UNC Libraries(2020)10.17615/9qfx-7w41

N/A

0DataRank · unranked

3 citations

Xi Chen, Jing Zhang, Qing Zhang, Xingnan Zheng, Katherine M. Aird +9 more

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

UNC Libraries(2020)10.17615/qv76-mh95

N/A

0DataRank · unranked

1 citations

Wai Leong Tam, X. Shirley Liu, Sandra J. Shin, Myles Brown, Jenny C. Chang +19 more

Cellular heterogeneity–adjusted clonal methylation (CHALM) provides better prediction of gene expression

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.23.961813

N/A

0DataRank · unranked

1 citations

Jiejun Shi, Xiaodong Cui, Ya Cui, Jingyi Jessica Li, Ajay Goel +5 more

The Cerebrospinal Fluid Provides a Proliferative Niche for Neural Progenitor Cells

UNC Libraries(2020)10.17615/rtb0-jc59

N/A

0DataRank · unranked

0 citations

Mauro W. Zappaterra, Xi Chen, A. Joseph D’Ercole, Ping Ye, Thomas M. Maynard +9 more

AI-based language models powering drug discovery and development

Drug Discovery Today(2021)10.1016/j.drudis.2021.06.009

N/A

0DataRank · unranked

158 citations

Ruth Roberts, Madhu Lal‐Nag, Xi Chen, Ruili Huang, Weida Tong +1 more

Systematic functional interrogation of human pseudogenes using CRISPRi

Genome biology(2021)10.1186/s13059-021-02464-2

N/A

0DataRank · unranked

32 citations

Yunfei Wang, Caishang Zheng, Yanjun Wei, Jiakai Hou, Peng Zhang +9 more

Cellular Heterogeneity–Adjusted cLonal Methylation (CHALM) improves prediction of gene expression

Nature Communications(2021)10.1038/s41467-020-20492-7

N/A

0DataRank · unranked

29 citations

Jiejun Shi, Xiaodong Cui, Ya Cui, Jingyi Jessica Li, Ajay Goel +5 more

Transglutaminase 2 Maintains Hepatocyte Growth Factor Signaling to Enhance the Cancer Cell Phenotype

Molecular Cancer Research(2021)10.1158/1541-7786.mcr-21-0306

N/A

0DataRank · unranked

8 citations

Gautam Adhikary, Suruchi Shrestha, Wen Xu, Jeffrey W. Keillor, Warren Naselsky +2 more

Notch-Induced Endoplasmic Reticulum-Associated Degradation Governs Thymocyte β−Selection

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.06.443041

N/A

0DataRank · unranked

0 citations

Jingjing Yu, Longyong Xu, Katharine Umphred-Wilson, Fanglue Peng, Yao Ding +9 more

Sex-specific DNA methylation changes in Alzheimer’s disease pathology

medRxiv(2021)10.1101/2021.03.01.21252029

N/A

0DataRank · unranked

0 citations

Juan I. Young, Lissette Gomez, Tiago C. Silva, Michael A. Schmidt, Jesse Cai +4 more

Bone Metastasis Initiation Is Coupled with Bone Remodeling through Osteogenic Differentiation of NG2+ Cells

Cancer Discovery(2022)10.1158/2159-8290.cd-22-0220

N/A

0DataRank · unranked

37 citations

Zhan Xu, Xiaoxin Hao, Tiancheng He, Jiasong Li, Yichao Shen +19 more

STAT5 confers lactogenic properties in breast tumorigenesis and restricts metastatic potential

Oncogene(2022)10.1038/s41388-022-02500-w

N/A

0DataRank · unranked

9 citations

Amy T. Ku, Jie Dong, Fei Yue, Weiyu Jiang, Ahmed Atef Ibrahim +14 more

Selective expression of neurodegenerative diseases-related mutant p150Glued in midbrain dopaminergic neurons causes progressive degeneration of nigrostriatal pathway

Ageing and Neurodegenerative Diseases(2022)10.20517/and.2022.07

N/A

0DataRank · unranked

1 citations

Carmelo Sgobio, Xuan Yang, Peng Yu, Xi Chen, Lixin Sun +3 more

VPS35 and α-Synuclein Fail to Interact to Modulate Neurodegeneration in Rodent Models of Parkinson’s Disease

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.07.519521

N/A

0DataRank · unranked

1 citations

Elpida Tsika, Nathan Levine, Darren J. Moore, Xi Chen

Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors

Science(2023)10.1126/science.abn4180

N/A

0DataRank · unranked

113 citations

Xuan Lu, Jin Cao, Qin Luo, Yao Ding, Fanglue Peng +34 more

CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer

Journal of Clinical Investigation(2023)10.1172/jci159940

N/A

0DataRank · unranked

46 citations

Yanjun Wei, Peng Zhang, Longyong Xu, Zhenzhen Zhang, Kangyu Lin +14 more

VPS35 and α-Synuclein fail to interact to modulate neurodegeneration in rodent models of Parkinson’s disease

Molecular Neurodegeneration(2023)10.1186/s13024-023-00641-4

N/A

0DataRank · unranked

8 citations

Elpida Tsika, Nathan Levine, Darren J. Moore, Xi Chen

Application of Proteostasis Regulators in GABAA Receptor Misfolding Diseases

Journal of Biomedical Research & Environmental Sciences(2023)10.37871/jbres1843

N/A

0DataRank · unranked

6 citations

Ting-Wei Mu, Yajuan Wang, Xi Chen

Cyclophilin A supports translation of intrinsically disordered proteins and affects haematopoietic stem cell ageing

Nature Cell Biology(2024)10.1038/s41556-024-01387-x

N/A

0DataRank · unranked

24 citations

Polina Iakova, Charles G. Lee, Shannon E. Moree, Xuan Lu, Gandhar Datar +15 more

A novel small molecule inhibitor of CD73 triggers immune-mediated multiple myeloma cell death

Blood Cancer Journal(2024)10.1038/s41408-024-01019-5

N/A

0DataRank · unranked

17 citations

Ting Du, Xueping Wan, Yan Song, Sindhu C Pillai, Md. Abu Musa +15 more

DNA Methylation Signature of a Lifestyle-based Resilience Index for Cognitive Health

Research Square(2024)10.21203/rs.3.rs-5423573/v1

N/A

0DataRank · unranked

2 citations

Wei Zhang, David Lukacsovich, Juan I. Young, Lissette Gomez, Michael A. Schmidt +6 more

Prolyl hydroxylase substrate adenylosuccinate lyase is an oncogenic driver in triple negative breast cancer

UNC Libraries(2024)10.17615/cca8-2d34

N/A

0DataRank · unranked

0 citations

Xi Chen, Baek Kim, Charles M. Perou, T.S Ptacek, Jean-Marc Simon +16 more

Crotonylation sensitizes IAPi-induced disruption of latent HIV by enhancing p100 cleavage into p52

UNC Libraries(2024)10.17615/8y53-ag31

N/A

0DataRank · unranked

0 citations

Guochun Jiang, Dajiang Li, David M. Margolis, Nancie M. Archin, Xi Chen +6 more

Carnosol attenuates Ang II-induced renal injury by p62-KEAP1-NRF2 signaling pathway

Toxicology and Applied Pharmacology(2025)10.1016/j.taap.2025.117528

N/A

0DataRank · unranked

2 citations

Ying‐Yong Zhao, Qingqing Zhao, Diyun Xu, Xi Chen, Jibo Han +4 more

Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease

Nature Communications(2020)10.1038/s41467-020-19791-w

N/A

0DataRank · unranked

159 citations

Tiago C. Silva, Juan I. Young, Lissette Gomez, Michael A. Schmidt, Kara L. Hamilton‐Nelson +5 more

Foxp3 M370I mutation allows the activation of T effector programs in regulatory T cells 3759

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.1524

N/A

0DataRank · unranked

0 citations

Angela M. Thornton, Kole Tison, Sung-Hwan Yoon, Joseph G. Gillen, Hyunwoo Chung +10 more

Inhibition of the MYC-Regulated Glutaminase Metabolic Axis Is an Effective Synthetic Lethal Approach for Treating Chemoresistant Ovarian Cancers

Cancer Research(2020)10.1158/0008-5472.can-19-3971

N/A

0DataRank · unranked

88 citations

Jiaxin Hong, Ryoichi Asaka, Shiho Asaka, Fang‐Chi Hsu, Yohan Suryo Rahmanto +15 more

12-h clock regulation of genetic information flow by XBP1s

PLoS Biology(2020)10.1371/journal.pbio.3000580

N/A

0DataRank · unranked

74 citations

Heather Ballance, Huan Meng, Naomi Gonzalez, Sam-Moon Kim, Leymaan Abdurehman +10 more

Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1922184117

N/A

0DataRank · unranked

71 citations

Elpida Tsika, Kaela Kelly, Nathan Levine, Xi Chen, Andrew B. West +4 more

Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions

Nature Cell Biology(2020)10.1038/s41556-020-00581-x

N/A

0DataRank · unranked

59 citations

Xia Liu, Fanglue Peng, Weijie Zhang, Liting Zheng, Yao Ding +22 more

Critical Roles of a RhoGEF-Anillin Module in Septin Architectural Remodeling during Cytokinesis

Current Biology(2020)10.1016/j.cub.2020.02.023

N/A

0DataRank · unranked

37 citations

Kangji Wang, Tatyana Svitkina, Erfei Bi, Xi Chen