🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Isak W. Tengesdal

Stanford University

ORCID: 0000-0002-8037-0428
Biochemistry, Genetics and Molecular BiologyImmunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile
0Author DataRank

Indexed papers

0in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 7 papers. Top paper: “Dapansutrile, an oral selective NLRP3 inflammasome inhibitor, for treatment of gout flares: an open-label, dose-adaptive, proof-of-concept, phase 2a trial”.

Dapansutrile, an oral selective NLRP3 inflammasome inhibitor, for treatment of gout flares: an open-label, dose-adaptive, proof-of-concept, phase 2a trial

The Lancet Rheumatology(2020)10.1016/s2665-9913(20)30065-5
N/A
0DataRank · unranked
296 citations

Tim Jansen, M. Janssen, Antoaneta Comarniceanu, M. Efdé, Isak W. Tengesdal +8 more

Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2000915118
N/A
0DataRank · unranked
194 citations

Dinoop Ravindran Menon, Douglas G. Osborne, C. Preston Neff, Nicholas E. Powers, Fabia Gamboni +17 more

Tumor NLRP3-Derived IL-1β Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression

Frontiers in Immunology(2021)10.3389/fimmu.2021.661323
N/A
0DataRank · unranked
127 citations

Alberto Dinarello, Nicholas E. Powers, Matthew A. Burchill, Leo A. B. Joosten, Carlo Marchetti +2 more

The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity

Cell Reports(2021)10.1016/j.celrep.2021.108955
N/A
0DataRank · unranked
72 citations

Isak W. Tengesdal, Mark S. Gresnigt, Travis Nemkov, Rob J.W. Arts, Jorge Domínguez‐Andrés +16 more

Activation of Host-NLRP3 Inflammasome in Myeloid Cells Dictates Response to Anti-PD-1 Therapy in Metastatic Breast Cancers

Pharmaceuticals(2022)10.3390/ph15050574
N/A
0DataRank · unranked
23 citations

Suzhao Li, Nicholas E. Powers, Makenna May, C. Preston Neff, Leo A. B. Joosten +3 more

IL-38 Gene Deletion Worsens Murine Colitis

Frontiers in Immunology(2022)10.3389/fimmu.2022.840719
N/A
0DataRank · unranked
16 citations

Ruth X. Wang, Jesús Amo‐Aparicio, J. Scott Lee, Alexander S. Dowdell, Isak W. Tengesdal +5 more

NLRP3 and cancer: Pathogenesis and therapeutic opportunities

Pharmacology & Therapeutics(2023)10.1016/j.pharmthera.2023.108545
N/A
0DataRank · unranked
49 citations

Charles A. Dinarello, Carlo Marchetti, Isak W. Tengesdal