John D. Crispino

Also affiliated with International Society for Experimental Hematology

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 20 papers. Top paper: “DYRK1A inhibition results in MYC and ERK activation rendering KMT2A-R acute lymphoblastic leukemia cells sensitive to BCL2 inhibition”.

DYRK1A inhibition results in MYC and ERK activation rendering KMT2A-R acute lymphoblastic leukemia cells sensitive to BCL2 inhibition

Leukemia(2025)10.1038/s41375-025-02575-w

N/A

0.219DataRank · unranked

3 citations

Gerald Wertheim, Shikha Gaur, John Chukinas, Joseph P. Loftus, Sung June Lee +15 more

Constitutive Activation of RAS/MAPK Pathway Cooperates with Trisomy 21 and Is Therapeutically Exploitable in Down Syndrome B-cell Leukemia

Clinical Cancer Research(2020)10.1158/1078-0432.ccr-19-3519

N/A

0DataRank · unranked

23 citations

Aurélie Siret, Cathy Ignacimouttou, Kunjal Panchal, M’Boyba Diop, Silvia Jenni +25 more

DYRK1A regulates B cell acute lymphoblastic leukemia through phosphorylation of FOXO1 and STAT3

Journal of Clinical Investigation(2021)10.1172/jci135937

N/A

0DataRank · unranked

90 citations

Malini Rammohan, Paul Lee, Anouchka P. Laurent, Qiang Wen, Praveen Suraneni +18 more

Clinical and biological aspects of myeloid leukemia in Down syndrome

Leukemia(2021)10.1038/s41375-021-01414-y

N/A

0DataRank · unranked

36 citations

Kenneth J. Caldwell, John D. Crispino, Jamie E. Flerlage, Austin Boucher

LKB1/ STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms

Cancer Discovery(2021)10.1158/2159-8290.cd-20-1353

N/A

0DataRank · unranked

46 citations

Praveen Suraneni, Hamza Celik, Andrew Volk, Qiang Wen, Te Ling +20 more

The Role of Megakaryocytes in Myelofibrosis

Hematology/Oncology Clinics of North America(2021)10.1016/j.hoc.2020.11.004

N/A

0DataRank · unranked

33 citations

Anna Ritá Migliaccio, John D. Crispino, Johanna Melo‐Cardenas

Building the Future Therapies for Down Syndrome: The Third International Conference of the T21 Research Society

Molecular Syndromology(2021)10.1159/000514437

N/A

0DataRank · unranked

10 citations

Yann Hérault, Pablo Helguera, María Martínez de Lagrán, Anna Vazquez, Bradley T. Christian +29 more

IL-13/IL-4 signaling contributes to fibrotic progression of the myeloproliferative neoplasms

Blood(2022)10.1182/blood.2022017326

N/A

0DataRank · unranked

64 citations

Lavanya Bezavada, Jeremy Chase Crawford, Sandeep Gurbuxani, Anitria Cotton, Guolian Kang +10 more

PU.1-c-Jun interaction is crucial for PU.1 function in myeloid development

Communications Biology(2022)10.1038/s42003-022-03888-7

N/A

0DataRank · unranked

46 citations

Boris Bartholdy, Yukiya Yamamoto, Erica Evans, Meritxell Alberich-Jordà, Philipp B. Staber +9 more

Discovery of a signaling feedback circuit that defines interferon responses in myeloproliferative neoplasms

Nature Communications(2022)10.1038/s41467-022-29381-7

N/A

0DataRank · unranked

25 citations

Jeremy Q. Wen, Ewa M. Kościuczuk, Frank Eckerdt, Elspeth M. Beauchamp, Chidera V. Oku +14 more

Gata1s mutant mice display persistent defects in the erythroid lineage

Blood Advances(2022)10.1182/bloodadvances.2022008124

N/A

0DataRank · unranked

11 citations

Kevin Zhang, Jiayue Yang, Sandeep Gurbuxani, John D. Crispino, Te Ling

Pharmacologic Inhibition of DYRK1A Results in MYC Hyperactivation and ERK Hyperphosphorylation rendering KMT2A -R ALL Cells Sensitive to BCL2 Inhibition

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.02.510349

N/A

0DataRank · unranked

0 citations

V.S.S. Abhinav Ayyadevara, Gerald Wertheim, John Chukinas, Joseph P. Loftus, Sung June Lee +13 more

Down syndrome and leukemia: from basic mechanisms to clinical advances

Haematologica(2023)10.3324/haematol.2023.283225

N/A

0DataRank · unranked

57 citations

Jean‐Pierre Bourquin, John D. Crispino, Sergi Cuartero, Henrik Hasle, Johann Hitzler +10 more

Building synthetic biosensors using red blood cell proteins

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.16.571988

N/A

0DataRank · unranked

4 citations

Taylor F. Gunnels, Te Ling, Kelly A. Sarnese, John D. Crispino, Joshua N. Leonard +1 more

Disruption of cotranscriptional splicing suggests RBM39 is a therapeutic target in acute lymphoblastic leukemia

Blood(2024)10.1182/blood.2024024281

N/A

0DataRank · unranked

4 citations

Ethan Harris, Jacquelyn Myers, Rashid Mehmood, Anitria Cotton, Hazheen K. Shirnekhi +16 more

Building Synthetic Biosensors Using Red Blood Cell Proteins

ACS Synthetic Biology(2024)10.1021/acssynbio.3c00754

N/A

0DataRank · unranked

3 citations

Taylor F. Gunnels, Te Ling, Kelly A. Sarnese, John D. Crispino, Joshua N. Leonard +1 more

Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast-phase MPN through targetable overexpression of DYRK1A

Nature Genetics(2025)10.1038/s41588-025-02190-6

N/A

0DataRank · unranked

9 citations

Bon Ham Yip, Giulia Orlando, Jeremy Q. Wen, Sean Wen, Harsh Goyal +36 more

Modeling GATA2 deficiency in mice: the R396Q mutation disrupts normal hematopoiesis

Leukemia(2025)10.1038/s41375-024-02508-z

N/A

0DataRank · unranked

4 citations

Rashid Mehmood, Diana Sá da Bandeira, Anitria Cotton, Jonathon Klein, Shondra M. Pruett‐Miller +4 more

FBXO11 is a candidate tumor suppressor in the leukemic transformation of myelodysplastic syndrome

Blood Cancer Journal(2020)10.1038/s41408-020-00362-7

N/A

0DataRank · unranked

33 citations

Christian Marinaccio, Lyndsey Bolanos, Wendy D. Haffey, Kenneth D. Greis, Daniel T. Starczynowski +2 more

RPS19 and RPL5 Haploinsufficient Models Reveal Divergent Ribosomal Subunit Controls of Fetal Hematopoiesis

Research Square(2025)10.21203/rs.3.rs-7563799/v1

N/A

0DataRank · unranked

0 citations

Yuefeng Tang, Te Ling, Rashid Mehmood, Alexis Bertrand, Julien Papoin +22 more