Nikolay V. Dokholyan

Biochemistry, Genetics and Molecular BiologyMaterials ScienceComputer ScienceMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 173 papers. Top paper: “Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer’s Disease, Parkinson’s Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis”.

Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer’s Disease, Parkinson’s Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis

Chemical Reviews(2021)10.1021/acs.chemrev.0c01122

N/A

7.3DataRank · unranked

672 citations

Ayyalusamy Ramamoorthy, Bikash R. Sahoo, Jie Zheng, Peter Faller, John E. Straub +29 more

Modifications to the Framework Regions Eliminate Chimeric Antigen Receptor Tonic Signaling

Cancer Immunology Research(2021)10.1158/2326-6066.cir-20-0451

N/A

0.655DataRank · unranked

78 citations

Giovanni Fucà, Jian Wang, Venkat R. Chirasani, Zhiyuan Yao, Elena Dukhovlinova +14 more

Ab initio RNA folding by discrete molecular dynamics: From structure prediction to folding mechanisms

UNC Libraries(2020)10.17615/1f7f-bw37

N/A

0.593DataRank · unranked

8 citations

F. Ding, N. E. Broude, P. Chalasani, S. Sharma, Nikolay V. Dokholyan +1 more

Molecular basis and cellular functions of vinculin-actin directional catch bonding

Nature Communications(2023)10.1038/s41467-023-43779-x

N/A

0.552DataRank · unranked

18 citations

M. Ashhar I. Khan, Juilee N. Malavade, Nikolay V. Dokholyan, Brenton D. Hoffman, Sharon L. Campbell +1 more

An engineered N-acyltransferase-LOV2 domain fusion protein enables light-inducible allosteric control of enzymatic activity

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.103069

N/A

0.473DataRank · unranked

11 citations

Yashavantha L. Vishweshwaraiah, Venkat R. Chirasani, J.R. Pritchard, Nikolay V. Dokholyan, Joshua Reynolds

MedusaScore: An Accurate Force Field-Based Scoring Function for Virtual Drug Screening

UNC Libraries(2020)10.17615/f0ng-3h40

N/A

0.429DataRank · unranked

7 citations

Nikolay V. Dokholyan, Shuangye Yin, Lada Biedermannová, Jiřı́ Vondrášek

Allosteric inactivation of an engineered optogenetic GTPase

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2219254120

N/A

0.428DataRank · unranked

12 citations

Nikolay V. Dokholyan, Andrew L. Lee, Abha Jain

Urolithin A analog inhibits castration-resistant prostate cancer by targeting the androgen receptor and its variant, androgen receptor-variant 7

Frontiers in Pharmacology(2023)10.3389/fphar.2023.1137783

N/A

0.360DataRank · unranked

10 citations

Ashish Tyagi, Uttara Saran, Venkatesh Kolluru, Becca V. Baby, Venkat R. Chirasani +7 more

ASR490, a Small Molecule, Overrides Aberrant Expression of Notch1 in Colorectal Cancer

Molecular Cancer Therapeutics(2020)10.1158/1535-7163.mct-19-0949

N/A

0.269DataRank · unranked

5 citations

Balaji Chandrasekaran, Venkatesh Kolluru, Becca V. Baby, Cibi A. Sripathi, Murali K. Ankem +6 more

Adaptation-proof SARS-CoV-2 vaccine design

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.17.492310

N/A

0.208DataRank · unranked

3 citations

Brianna Hnath, Brendan Rackley, Jian Wang, Abhinay Gontu, Morgan Chandler +6 more

Yuel : Compound-Protein Interaction Prediction with High Generalizability

10.1101/2021.07.06.451043

N/A

0.165DataRank · unranked

2 citations

Nikolay V. Dokholyan, Jian Wang

Protein folding: Then and now

UNC Libraries(2020)10.17615/0reh-5583

N/A

0.165DataRank · unranked

2 citations

Shantanu Sharma, Adrian W.R. Serohijos, Shuangye Yin, Yiwen Chen, Kyle C. Wilcox +3 more

Human transporter de-oligomerization regulates copper uptake into cells

Research Square(2024)10.21203/rs.3.rs-5456520/v1

N/A

0.104DataRank · unranked

1 citations

Meng‐Hsuan Wen, Huanhuan Chen, Guangjie Yan, Yuteng Zhang, Wenkai Chen +4 more

The rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosis

UNC Libraries(2020)10.17615/vn3t-aw26

N/A

0DataRank · unranked

7 citations

M. Caplow, Nikolay V. Dokholyan, S. D. Khare

RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme

UNC Libraries(2020)10.17615/rh9e-gx23

N/A

0DataRank · unranked

5 citations

Janusz M. Bujnicki, Feng Ding, Greggory M. Rice, Wipapat Kladwang, J.J. Trausch +41 more

Multiple Membrane-Cytoplasmic Domain Contacts in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Mediate Regulation of Channel Gating

UNC Libraries(2020)10.17615/mmwz-st78

N/A

0DataRank · unranked

5 citations

Tamás Hegedűs, Andrei A. Aleksandrov, Luba A. Aleksandrov, Adrian W.R. Serohijos, Nikolay V. Dokholyan +3 more

Prefusion spike protein stabilization through computational mutagenesis

Proteins Structure Function and Bioinformatics(2020)10.1002/prot.26025

N/A

0DataRank · unranked

5 citations

Jian Wang, Nikolay V. Dokholyan, Dong Yan Zhang

Natural Selection against Protein Aggregation on Self-Interacting and Essential Proteins in Yeast, Fly, and Worm

UNC Libraries(2020)10.17615/vm34-e107

N/A

0DataRank · unranked

5 citations

Nikolay V. Dokholyan, Yiwen Chen

On the significance of an RNA tertiary structure prediction

UNC Libraries(2020)10.17615/t0vq-d909

N/A

0DataRank · unranked

4 citations

K. M. Weeks, C. E. Hajdin, Nikolay V. Dokholyan, F. Ding

Imprint of evolution on protein structures

UNC Libraries(2020)10.17615/0sad-c810

N/A

0DataRank · unranked

4 citations

Eugene I. Shakhnovich, Boris E. Shakhnovich, G. Tiana, Nikolay V. Dokholyan

COMT gene locus: new functional variants

UNC Libraries(2020)10.17615/t3w9-4937

N/A

0DataRank · unranked

3 citations

Richard Ohrbach, Ilkka Reenilä, William Maixner, Samantha K. Segall, Marjo Piltonen +16 more

Structural Determinants of Skeletal Muscle Ryanodine Receptor Gating

UNC Libraries(2020)10.17615/e8ca-w452

N/A

0DataRank · unranked

1 citations

Yingwu Mei, Montserrat Samsó, Srinivas Ramachandran, Asima Chakraborty, Gerhard Meissner +2 more

Dynamics Intrinsic to Cystic Fibrosis Transmembrane Conductance Regulator Function and Stability

UNC Libraries(2020)10.17615/rdt8-r334

N/A

0DataRank · unranked

1 citations

P. Kota, P. A. Chong, Nikolay V. Dokholyan, Julie D. Forman‐Kay

Knowledge-Based Design of a Biosensor to Quantify Localized ERK Activation in Living Cells

UNC Libraries(2020)10.17615/aq71-e362

N/A

0DataRank · unranked

1 citations

Chia Wen Hsu, Nikolay V. Dokholyan, Melanie Kaufholz, Bastian Zimmermann, Onur Dağliyan +4 more

The structural heterogeneity of α-synuclein is governed by several distinct subpopulations with interconversion times slower than milliseconds

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.09.374991

N/A

0DataRank · unranked

5 citations

Sofia Zaer, Paz Drori, Joanna Zamel, Khalil Joron, Nir Kalisman +3 more

Computational approaches to understanding protein aggregation in neurodegeneration

UNC Libraries(2020)10.17615/5245-ge54

N/A

0DataRank · unranked

0 citations

Tandon, A., Proctor, E. A., Redler, R. L., Doo Nam Kim, Ding, F. +5 more

Prefusion spike protein stabilization through computational mutagenesis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.17.157081

N/A

0DataRank · unranked

0 citations

Jian Wang, Nikolay V. Dokholyan, Dong Yan Zhang

Identification of an Actin Binding Surface on Vinculin that Mediates Mechanical Cell and Focal Adhesion Properties

UNC Libraries(2020)10.17615/ev9w-xz44

N/A

0DataRank · unranked

0 citations

Sharon L. Campbell, Kai Shen, Sean M. Palmer, Karen M. Plevock, Caitlin E. Tolbert +8 more

Computational Studies Reveal Phosphorylation-dependent Changes in the Unstructured R Domain of CFTR

UNC Libraries(2020)10.17615/dpsz-v306

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, John R. Riordan, Tamás Hegedűs, Adrian W.R. Serohijos, Lihua He

Rigid substructure search

UNC Libraries(2020)10.17615/g5c8-wz70

N/A

0DataRank · unranked

0 citations

Anastassia N. Alexandrova, Nikolay V. Dokholyan, David Shirvanyants

Solving protein structures using short-distance cross-linking constraints as a guide for discrete molecular dynamics simulations

UNC Libraries(2020)10.17615/49hd-1e89

N/A

0DataRank · unranked

0 citations

Christoph H. Borchers, Evgeniy V. Petrotchenko, Nicholas I. Brodie, Konstantin I. Popov, Nikolay V. Dokholyan

Discrete Molecular Dynamics Distinguishes Nativelike Binding Poses from Decoys in Difficult Targets

UNC Libraries(2020)10.17615/v9jg-9039

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Shuangye Yin, Alexander Tropsha, Elizabeth A. Proctor

Energetic and Structural Basis for Activation of the Epithelial Sodium Channel by Matriptase

Figshare(2020)10.17615/c3fq-z529

N/A

0DataRank · unranked

0 citations

Hong Dang, Agustı́n Garcı́a-Caballero, Nikolay V. Dokholyan, M. Jackson Stutts, Pradeep Kota +1 more

Light Regulation of Protein Dimerization and Kinase Activity in Living Cells Using Photocaged Rapamycin and Engineered FKBP

Figshare(2020)10.17615/5pz5-7c82

N/A

0DataRank · unranked

0 citations

Andrei V. Karginov, Yan Zou, Nikolay V. Dokholyan, Pradeep Kota, Klaus M. Hahn +3 more

The N-terminal Domain Allosterically Regulates Cleavage and Activation of the Epithelial Sodium Channel

UNC Libraries(2020)10.17615/4twx-3c24

N/A

0DataRank · unranked

0 citations

Yan L. Dang, M. Jackson Stutts, Hong He, Guilherme J. M. Garcia, Pradeep Kota +5 more

iFoldRNA: three-dimensional RNA structure prediction and folding

UNC Libraries(2020)10.17615/f0ht-5585

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Feng Ding, Shantanu Sharma

Allosteric Modulation Balances Thermodynamic Stability and Restores Function of ΔF508 CFTR

UNC Libraries(2020)10.17615/xppw-vb14

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Santiago Reyes, Alexey E. Alekseev, Pradeep Kota, Martina Gentzsch +6 more

Gaia: automated quality assessment of protein structure models

UNC Libraries(2020)10.17615/t2ch-ad23

N/A

0DataRank · unranked

0 citations

Pradeep Kota, Srinivas Ramachandran, Feng Ding, Nikolay V. Dokholyan

Restoration of R117H CFTR folding and function in human airway cells through combination treatment with VX-809 and VX-770

UNC Libraries(2020)10.17615/pgag-s631

N/A

0DataRank · unranked

0 citations

Deborah M. Cholon, Jhuma Das, Pattarawut Sopha, Nikolay V. Dokholyan, Imron G. Chaudhry +6 more

Principles for Understanding the Accuracy of SHAPE-Directed RNA Structure Modeling

UNC Libraries(2020)10.17615/wv1r-nd02

N/A

0DataRank · unranked

0 citations

Christine E. Hajdin, Kevin M. Weeks, Oleg V. Favorov, David H. Mathews, Christopher W. Leonard +2 more

Glutathionylation at Cys-111 Induces Dissociation of Wild Type and FALS Mutant SOD1 Dimers

Figshare(2020)10.17615/004f-1j62

N/A

0DataRank · unranked

0 citations

Elizabeth A. Proctor, Rachel L. Redler, Kyle C. Wilcox, Lanette Fee, Michael Caplow +1 more

A Didactic Model of Macromolecular Crowding Effects on Protein Folding

UNC Libraries(2020)10.17615/ffcf-0b43

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Allen P. Minton, Douglas Tsao

A Structural Model of the Pore-Forming Region of the Skeletal Muscle Ryanodine Receptor (RyR1)

UNC Libraries(2020)10.17615/2pe9-4h32

N/A

0DataRank · unranked

0 citations

Adrian W.R. Serohijos, Le Xu, Srinivas Ramachandran, Nikolay V. Dokholyan, Gerhard Meissner

A Structural Model for Vinculin Insertion into PIP 2 -Containing Membranes and the Effect of Insertion on Vinculin Activation and Localization

UNC Libraries(2020)10.17615/can9-va51

N/A

0DataRank · unranked

0 citations

Clare M. Waterman, Mihir Pershad, Caitlin E. Tolbert, Srinivas Ramachandran, Arpit Tandon +4 more

Non-canonical Bromodomain within DNA-PKcs Promotes DNA Damage Response and Radioresistance through Recognizing an IR-Induced Acetyl-Lysine on H2AX

UNC Libraries(2020)10.17615/mned-p064

N/A

0DataRank · unranked

0 citations

Feng Liu, Jian Jin, Nikolay V. Dokholyan, Xian Chen, Brian D. Strahl +9 more

Direct identification of base-paired RNA nucleotides by correlated chemical probing

UNC Libraries(2020)10.17615/4wac-ga43

N/A

0DataRank · unranked

0 citations

A. Krokhotin, Nikolay V. Dokholyan, Kevin M. Weeks, Anthony M. Mustoe

Flanking Bases Influence the Nature of DNA Distortion by Platinum 1,2-Intrastrand (GG) Cross-Links

UNC Libraries(2020)10.17615/m4ef-pb13

N/A

0DataRank · unranked

0 citations

Stephen G. Chaney, Sharon L. Campbell, Candice L. King, James A. Swenberg, Shantanu Sharma +6 more

Engineering extrinsic disorder to control protein activity in living cells

UNC Libraries(2020)10.17615/dz8z-st19

N/A

0DataRank · unranked

0 citations

Ilme Schlichting, Pei‐Hsuan Chu, Miroslaw Tarnawski, Klaus M. Hahn, Nikolay V. Dokholyan +2 more

Three-dimensional RNA structure refinement by hydroxyl radical probing

UNC Libraries(2020)10.17615/8erj-np72

N/A

0DataRank · unranked

0 citations

Christopher A. Lavender, Feng Ding, Nikolay V. Dokholyan, Kevin M. Weeks

Traffic within the Cytochrome b 6 f Lipoprotein Complex: Gating of the Quinone Portal

UNC Libraries(2020)10.17615/8e8b-bm47

N/A

0DataRank · unranked

0 citations

Elizabeth A. Proctor, Eiki Yamashita, S. Saif Hasan, Nikolay V. Dokholyan, William A. Cramer

Automated minimization of steric clashes in protein structures

UNC Libraries(2020)10.17615/kcd9-3213

N/A

0DataRank · unranked

0 citations

Feng Ding, Srinivas Ramachandran, Pradeep Kota, Nikolay V. Dokholyan

Regulation of the epithelial Na+ channel and airway surface liquid volume by serine proteases

UNC Libraries(2020)10.17615/y9bg-2s82

N/A

0DataRank · unranked

0 citations

M. Jackson Stutts, Erol Gaillard, Martina Gentzsch, Nikolay V. Dokholyan, Robert Tarran +1 more

Local Unfolding of Cu, Zn Superoxide Dismutase Monomer Determines the Morphology of Fibrillar Aggregates

UNC Libraries(2020)10.17615/0948-hd95

N/A

0DataRank · unranked

0 citations

Feng Ding, Nikolay V. Dokholyan, Nobuyuki Nukina, Yoshiaki Furukawa

Structure modeling of RNA using sparse NMR constraints

UNC Libraries(2020)10.17615/gp3h-p817

N/A

0DataRank · unranked

0 citations

Qi Zhang, Benfeard Williams, Arpit Tandon, Nikolay V. Dokholyan, Bo Zhao +2 more

Regulatory Insertion Removal Restores Maturation, Stability and Function of ΔF508 CFTR

UNC Libraries(2020)10.17615/zf61-3n19

N/A

0DataRank · unranked

0 citations

Pradeep Kota, Andrei A. Aleksandrov, Luba A. Aleksandrov, Tim Kåre Jensen, Liying Cui +4 more

Structural Mechanism of S-Adenosyl Methionine Binding to Catechol O-Methyltransferase

UNC Libraries(2020)10.17615/k44r-vq15

N/A

0DataRank · unranked

0 citations

Douglas Tsao, Nikolay V. Dokholyan, Luda Diatchenko

ApoE4-specific Misfolded Intermediate Identified by Molecular Dynamics Simulations

UNC Libraries(2020)10.17615/v5hc-qz44

N/A

0DataRank · unranked

0 citations

Jhuma Das, Benfeard Williams, Nikolay V. Dokholyan, Marino Convertino

Macromolecular crowding induces polypeptide compaction and decreases folding cooperativity

UNC Libraries(2020)10.17615/a398-6s98

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Douglas Tsao

A Phosphomimetic Mutation Stabilizes SOD1 and Rescues Cell Viability in the Context of an ALS-Associated Mutation

UNC Libraries(2020)10.17615/38be-7s73

N/A

0DataRank · unranked

0 citations

Wenjun Cui, Yazhong Tao, Nikolay V. Dokholyan, James M. Fay, Elizabeth A. Proctor +2 more

Applications of Discrete Molecular Dynamics in biology and medicine

UNC Libraries(2020)10.17615/bf0f-nz11

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Elizabeth A. Proctor

Approaches for probing the sequence space of substrates recognized by molecular chaperones

UNC Libraries(2020)10.17615/tkkz-qb77

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Pradeep Kota

Identification and Rational Redesign of Peptide Ligands to CRIP1, A Novel Biomarker for Cancers

UNC Libraries(2020)10.17615/vmr7-2w77

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Gina Tassone, Adrian W.R. Serohijos, Dennis C. Sgroi, James P. Basilion +3 more

Thermodynamic Stability of Histone H3 Is a Necessary but not Sufficient Driving Force for its Evolutionary Conservation

UNC Libraries(2020)10.17615/trh0-9q98

N/A

0DataRank · unranked

0 citations

Brian D. Strahl, Lisa Vogel, Srinivas Ramachandran, Nikolay V. Dokholyan

Statistical Analysis of SHAPE-Directed RNA Secondary Structure Modeling

UNC Libraries(2020)10.17615/5ybt-4921

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Kevin M. Weeks, Srinivas Ramachandran, Feng Ding

Differential Regulation of 6- and 7-Transmembrane Helix Variants of μ-Opioid Receptor in Response to Morphine Stimulation

UNC Libraries(2020)10.17615/30r1-4284

N/A

0DataRank · unranked

0 citations

Reza Sharif‐Naeini, Brian L. Schmidt, Josée Gauthier, Marino Convertino, William Maixner +5 more

Physical Microscopic Model of Proteins Under Force

UNC Libraries(2020)10.17615/qwta-g502

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan

Computational Design of a PAK1 Binding Protein

UNC Libraries(2020)10.17615/t43c-a350

N/A

0DataRank · unranked

0 citations

Brian Kuhlman, Ramesh K. Jha, Thomas Szyperski, Yibing Wu, Andrew Leaver-Fay +3 more

Cheminformatics Meets Molecular Mechanics: A Combined Application of Knowledge-Based Pose Scoring and Physical Force Field-Based Hit Scoring Functions Improves the Accuracy of Structure-Based Virtual Screening

Figshare(2020)10.17615/y79v-wy82

N/A

0DataRank · unranked

0 citations

Xiang S. Wang, Shubin Liu, Alexander Tropsha, Shuangye Yin, Nikolay V. Dokholyan +1 more

N-terminal strands of filamin Ig domains act as a conformational switch under biological forces

UNC Libraries(2020)10.17615/tp2w-9w11

N/A

0DataRank · unranked

0 citations

Feng Ding, Nikolay V. Dokholyan, Brenda Temple, Barry Kesner

Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels

UNC Libraries(2020)10.17615/72jx-xg45

N/A

0DataRank · unranked

0 citations

Daniel A. Pasek, Gerhard Meissner, Ashutosh Tripathy, Srinivas Ramachandran, Nikolay V. Dokholyan +1 more

Predicting the functional consequences of non-synonymous single nucleotide polymorphisms in IL8 gene

UNC Libraries(2020)10.17615/525e-fd10

N/A

0DataRank · unranked

0 citations

Vinod Kumar Yadav, Gourav Dhiman, Deepak Kala, Nikolay V. Dokholyan, A. Krokhotin +1 more

Engineered allosteric activation of kinases in living cells

UNC Libraries(2020)10.17615/xfxv-8h61

N/A

0DataRank · unranked

0 citations

Klaus M. Hahn, Pradeep Kota, Nikolay V. Dokholyan, Andrei V. Karginov, Feng Ding

Predicting Binding Affinity of CSAR Ligands Using Both Structure-Based and Ligand-Based Approaches

UNC Libraries(2020)10.17615/733t-6r44

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Eugene Muratov, Feng Ding, Denis Fourches, Alexander Tropsha

Structural and Thermodynamic Effects of Post-translational Modifications in Mutant and Wild Type Cu, Zn Superoxide Dismutase

UNC Libraries(2020)10.17615/ghd8-9n16

N/A

0DataRank · unranked

0 citations

Feng Ding, Elizabeth A. Proctor, Nikolay V. Dokholyan

Transmembrane helical interactions in the CFTR channel pore

UNC Libraries(2020)10.17615/qpwq-8t78

N/A

0DataRank · unranked

0 citations

Andrei A. Aleksandrov, Lihua He, Jhuma Das, Liying Cui, Nikolay V. Dokholyan +1 more

Submillisecond Elastic Recoil Reveals Molecular Origins of Fibrin Fiber Mechanics

UNC Libraries(2020)10.17615/qz58-w135

N/A

0DataRank · unranked

0 citations

Feng Ding, E. Timothy O’Brien, Richard Superfine, Nikolay V. Dokholyan, Nathan E. Hudson +4 more

Non-native Soluble Oligomers of Cu/Zn Superoxide Dismutase (SOD1) Contain a Conformational Epitope Linked to Cytotoxicity in Amyotrophic Lateral Sclerosis (ALS)

UNC Libraries(2020)10.17615/je7q-ev31

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Rachel L. Redler, Michael Caplow, Lanette Fee, James M. Fay

A structural model reveals energy transduction in dynein

UNC Libraries(2020)10.17615/vz5t-ex52

N/A

0DataRank · unranked

0 citations

T. C. Elston, Nikolay V. Dokholyan, A. W. R. Serohijos, F. Ding, Y. Chen

Rational coupled dynamics network manipulation rescues disease-relevant mutant cystic fibrosis transmembrane conductance regulator

UNC Libraries(2020)10.17615/fg5n-5z75

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Andrei A. Aleksandrov, Elizabeth A. Proctor, Lihua He, John R. Riordan +1 more

Structural Basis for μ-Opioid Receptor Binding and Activation

UNC Libraries(2020)10.17615/ajfv-y762

N/A

0DataRank · unranked

0 citations

Luda Diatchenko, William Maixner, Nikolay V. Dokholyan, Adrian W.R. Serohijos, Feng Ding +3 more

Fingerprint-based structure retrieval using electron density

UNC Libraries(2020)10.17615/ay2s-jm96

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Shuangye Yin

Gain-of-Function Mutation W493R in the Epithelial Sodium Channel Allosterically Reconfigures Intersubunit Coupling

UNC Libraries(2020)10.17615/hdex-ks42

N/A

0DataRank · unranked

0 citations

Pradeep Kota, Yan L. Dang, Onur Dağliyan, Hong S. He, Mahmoud Shobair +2 more

Identification of a consensus motif in substrates bound by a Type I Hsp40

UNC Libraries(2020)10.17615/b35c-mk48

N/A

0DataRank · unranked

0 citations

P. Kota, Nikolay V. Dokholyan, D. M. Cyr, D. W. Summers, H.-Y. Ren

Cu,Zn-Superoxide Dismutase without Zn Is Folded but Catalytically Inactive

UNC Libraries(2020)10.17615/tyqz-hm62

N/A

0DataRank · unranked

0 citations

Elizabeth A. Proctor, Rachel L. Redler, Sean Nedd, Nikolay V. Dokholyan, Anastassia N. Alexandrova

Structural basis for the sequence-dependent effects of platinum–DNA adducts

UNC Libraries(2020)10.17615/qb08-4g56

N/A

0DataRank · unranked

0 citations

Srinivas Ramachandran, Brenda Temple, Stephen G. Chaney, Nikolay V. Dokholyan

New Models of Tetrahymena Telomerase RNA from Experimentally Derived Constraints and Modeling

Figshare(2020)10.17615/6xfg-y091

N/A

0DataRank · unranked

0 citations

Daud Cole, Nikolay V. Dokholyan, Laura N. Bonifacio, Feng Ding, Vijay G. Sekaran +2 more

Kinetic models for the coordinated stepping of cytoplasmic dynein

UNC Libraries(2020)10.17615/9qzd-vd70

N/A

0DataRank · unranked

0 citations

Timothy C. Elston, Denis Tsygankov, Nikolay V. Dokholyan, Adrian W.R. Serohijos

Native-like RNA Tertiary Structures Using a Sequence-Encoded Cleavage Agent and Refinement by Discrete Molecular Dynamics

UNC Libraries(2020)10.17615/y5qt-y449

N/A

0DataRank · unranked

0 citations

Kevin M. Weeks, Christopher W. Leonard, Costin M. Gherghe, Feng Ding, Nikolay V. Dokholyan

Multiscale approaches for studying energy transduction in dynein

UNC Libraries(2020)10.17615/dd2t-fq52

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Timothy C. Elston, Denis Tsygankov, Shubin Liu, Adrian W.R. Serohijos

A Physical Model Reveals the Mechanochemistry Responsible for Dynein's Processive Motion

UNC Libraries(2020)10.17615/y7mq-vr80

N/A

0DataRank · unranked

0 citations

Denis Tsygankov, Nikolay V. Dokholyan, Adrian W.R. Serohijos, Timothy C. Elston

The structural heterogeneity of α-synuclein is governed by several distinct subpopulations with interconversion times slower than milliseconds

Structure(2021)10.1016/j.str.2021.05.002

N/A

0DataRank · unranked

58 citations

Sofia Zaer, Paz Drori, Joanna Zamel, Khalil Joron, Nir Kalisman +3 more

SOD1 oligomers in amyotrophic lateral sclerosis

Current Opinion in Structural Biology(2021)10.1016/j.sbi.2020.12.002

N/A

0DataRank · unranked

39 citations

Nikolay V. Dokholyan, Esther Choi

Direct Mapping of Higher-Order RNA Interactions by SHAPE-JuMP

Biochemistry(2021)10.1021/acs.biochem.1c00270

N/A

0DataRank · unranked

37 citations

Catherine A. Giannetti, Gillian Houlihan, Matthew J. Smola, Greggory M. Rice, Jian Wang +5 more

Engineering an Allosteric Control of Protein Function

The Journal of Physical Chemistry B(2021)10.1021/acs.jpcb.0c11640

N/A

0DataRank · unranked

35 citations

Jiaxing Chen, Nikolay V. Dokholyan, Yashavantha L. Vishweshwaraiah

GPU-Accelerated Flexible Molecular Docking

The Journal of Physical Chemistry B(2021)10.1021/acs.jpcb.0c09051

N/A

0DataRank · unranked

34 citations

Jian Wang, Huaipan Jiang, Yilin Feng, Mehrdad Mahdavi, Kamesh Madduri +3 more

Mechanical Counterbalance of Kinesin and Dynein Motors in a Microtubular Network Regulates Cell Mechanics, 3D Architecture, and Mechanosensing

ACS Nano(2021)10.1021/acsnano.1c04435

N/A

0DataRank · unranked

22 citations

Alexis Manning, Chynna Smith, James B. Hayes, Dylan T. Burnette, Jian Wang +5 more

Structure of prion β‐oligomers as determined by short‐distance crosslinking constraint‐guided discrete molecular dynamics simulations

PROTEOMICS(2021)10.1002/pmic.202000298

N/A

0DataRank · unranked

18 citations

Konstantin I. Popov, Evgeniy V. Petrotchenko, Nikolay V. Dokholyan, Christoph H. Borchers, Jason J. Serpa

Mapping co‐regulatory interactions among ligand‐binding sites in ryanodine receptor 1

Proteins Structure Function and Bioinformatics(2021)10.1002/prot.26228

N/A

0DataRank · unranked

5 citations

Konstantin I. Popov, Gerhard Meissner, Nikolay V. Dokholyan, Venkat R. Chirasani

GM1 mediates the formation and maintenance of cytotoxic Aβ oligomers

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.22.453392

N/A

0DataRank · unranked

0 citations

Jian Wang, Rebecca M. Fleeman, Madison K. Kuhn, Matthew T. Swulius, Elizabeth A. Proctor +2 more

Robust and Efficient Assessment of Potency (REAP): A Quantitative Tool for Dose-response Curve Estimation

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.20.469388

N/A

0DataRank · unranked

0 citations

Xinyi Liu, Xinying Fang, Vernon M. Chinchilli, Michael Wang, Honggang Wang +4 more

Intra- and Inter-Subunit Disulfide Bond Formation Is Nonessential in Adeno-Associated Viral Capsids

UNC Libraries(2021)10.17615/qbp2-t928

N/A

0DataRank · unranked

0 citations

Aravind Asokan, Nagesh Pulicherla, Pradeep Kota, Nikolay V. Dokholyan

Topological Determinants of Protein Domain Swapping

UNC Libraries(2021)10.17615/8r14-9196

N/A

0DataRank · unranked

0 citations

Sharon L. Campbell, Kirk C. Prutzman, Feng Ding, Nikolay V. Dokholyan

mRNA vaccines for cancer immunotherapy

Frontiers in Immunology(2022)10.3389/fimmu.2022.1029069

N/A

0DataRank · unranked

163 citations

Nikolay V. Dokholyan, Yashavantha L. Vishweshwaraiah

AlphaFold illuminates half of the dark human proteins

Current Opinion in Structural Biology(2022)10.1016/j.sbi.2022.102372

N/A

0DataRank · unranked

91 citations

Joel Berendzen, Amy O. Stevens, Yi He, Jian Wang, Nikolay V. Dokholyan +2 more

Predicting Protein–Ligand Docking Structure with Graph Neural Network

Journal of Chemical Information and Modeling(2022)10.1021/acs.jcim.2c00127

N/A

0DataRank · unranked

70 citations

Jian Wang, Weilin Cong, Yihe Huang, Morteza Ramezani, Anup Sarma +4 more

Anhydrous Nucleic Acid Nanoparticles for Storage and Handling at Broad Range of Temperatures

Small(2022)10.1002/smll.202104814

N/A

0DataRank · unranked

25 citations

Morgan Chandler, Justin R. Halman, Damian Beasock, Adam B. Fessler, Riley Q. McKeough +9 more

Toxic SOD1 trimers are off-pathway in the formation of amyloid-like fibrils in ALS

Biophysical Journal(2022)10.1016/j.bpj.2022.04.037

N/A

0DataRank · unranked

20 citations

Nikolay V. Dokholyan, Brianna Hnath

Activation of Disulfide Redox Switch in REDD1 Promotes Oxidative Stress Under Hyperglycemic Conditions

Diabetes(2022)10.2337/db22-0355

N/A

0DataRank · unranked

15 citations

Congzhou M. Sha, Siddharth Sunilkumar, Allyson L. Toro, Ashley M. VanCleave, Scot R. Kimball +3 more

Whole proteome mapping of compound-protein interactions

Current Research in Chemical Biology(2022)10.1016/j.crchbi.2022.100035

N/A

0DataRank · unranked

13 citations

Jian Wang, Congzhou M. Sha, Wesley M. Raup‐Konsavage, Kent E. Vrana, Nikolay V. Dokholyan +1 more

NeuralDock: Rapid and Conformation-Agnostic Docking of Small Molecules

Frontiers in Molecular Biosciences(2022)10.3389/fmolb.2022.867241

N/A

0DataRank · unranked

9 citations

Jian Wang, Nikolay V. Dokholyan, Congzhou M. Sha

Monosialotetrahexosylganglioside Promotes Early Aβ42 Oligomer Formation and Maintenance

ACS Chemical Neuroscience(2022)10.1021/acschemneuro.2c00221

N/A

0DataRank · unranked

15 citations

Jian Wang, Rebecca M. Fleeman, Madison K. Kuhn, Matthew T. Swulius, Elizabeth A. Proctor +2 more

Adaptation‐Proof SARS‐CoV‐2 Vaccine Design

Advanced Functional Materials(2022)10.1002/adfm.202206055

N/A

0DataRank · unranked

14 citations

Brianna Hnath, Brendan Rackley, Jian Wang, Abhinay Gontu, Morgan Chandler +6 more

Dopamine D1 receptor-mediated β-arrestin signaling: Insight from pharmacology, biology, behavior, and neurophysiology

The International Journal of Biochemistry & Cell Biology(2022)10.1016/j.biocel.2022.106235

N/A

0DataRank · unranked

10 citations

Mechelle M. Lewis, Xuemei Huang, Nikolay V. Dokholyan, Richard B. Mailman, Yang Yang

Motor neuron-derived induced pluripotent stem cells as a drug screening platform for amyotrophic lateral sclerosis

Frontiers in Cell and Developmental Biology(2022)10.3389/fcell.2022.962881

N/A

0DataRank · unranked

9 citations

Esther Choi, Axel R. Cofré, Nikolay V. Dokholyan, Marcelo Duzzioni, Mariana A. Amorós

Predicting 3D RNA structure from solely the nucleotide sequence using Euclidean distance neural networks

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.16.492153

N/A

0DataRank · unranked

1 citations

Jian Wang, Nikolay V. Dokholyan, Congzhou M. Sha

Multifunctions of α‐Synuclein Explained by Its Dynamic Heterogeneous Conformations with a Hierarchy of Transition Times

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.l8019

N/A

0DataRank · unranked

0 citations

Sofia Zaer, Paz Drori, Joanna Zamel, Khalil Joron, Nir Kalisman +3 more

Editorial to “Molecular engineering of biomaterials programmed to operate in living systems”

Advanced Drug Delivery Reviews(2022)10.1016/j.addr.2022.114669

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Kirill A. Afonin

Structural and dynamic insights into α-synuclein dimer conformations

Structure(2023)10.1016/j.str.2023.01.011

N/A

0DataRank · unranked

25 citations

Jiaxing Chen, Sofia Zaer, Paul David Harris, Paz Drori, Mario Lebendiker +4 more

A noncommutative combinatorial protein logic circuit controls cell orientation in nanoenvironments

Science Advances(2023)10.1126/sciadv.adg1062

N/A

0DataRank · unranked

22 citations

Yashavantha L. Vishweshwaraiah, Richard B. Mailman, Erdem D. Tabdanov, Nikolay V. Dokholyan, Jiaxing Chen

Predicting 3D RNA structure from the nucleotide sequence using Euclidean neural networks

Biophysical Journal(2023)10.1016/j.bpj.2023.10.011

N/A

0DataRank · unranked

18 citations

Jian Wang, Nikolay V. Dokholyan, Congzhou M. Sha

Vitamin D Receptor Antagonist MeTC7 Inhibits PD-L1

Cancers(2023)10.3390/cancers15133432

N/A

0DataRank · unranked

13 citations

Emily R. Quarato, Niloy A. Singh, Cameron Snyder, Taylor Moore, John Miller +34 more

Deciphering the Mechanistic Basis for Perfluoroalkyl‐Protein Interactions

ChemBioChem(2023)10.1002/cbic.202300159

N/A

0DataRank · unranked

12 citations

Janna N. Sloand, Mariangely González Vargas, Harminder Singh, Tomer Eldor, Michael A. Miller +7 more

Big versus small: The impact of aggregate size in disease

Protein Science(2023)10.1002/pro.4686

N/A

0DataRank · unranked

11 citations

Jiaxing Chen, Joshua Reynolds, Esther Choi, Jian Wang, Dongyan Zhang +3 more

Allosteric regulation of kinase activity in living cells

eLife(2023)10.7554/elife.90574.4

N/A

0DataRank · unranked

6 citations

Nikolay V. Dokholyan, S. Godbole

Allosteric regulation of kinase activity in living cells

eLife(2023)10.7554/elife.90574

N/A

0DataRank · unranked

2 citations

Nikolay V. Dokholyan, S. Godbole

Differentiable rotamer sampling with molecular force fields

Briefings in Bioinformatics(2023)10.1093/bib/bbad456

N/A

0DataRank · unranked

2 citations

Jian Wang, Nikolay V. Dokholyan, Congzhou M. Sha

Microcalorimetry reveals multi-state thermal denaturation of G. stearothermophilus tryptophanyl-tRNA synthetase

Structural Dynamics(2023)10.1063/4.0000181

N/A

0DataRank · unranked

2 citations

Jhuma Das, Nikolay V. Dokholyan, Charles W. Carter, Srinivas Niranj Chandrasekaran

Elucidation of the Molecular Basis and Cellular Functions of Vinculin-Actin Directional Catch Bonding

Research Square(2023)10.21203/rs.3.rs-2334490/v1

N/A

0DataRank · unranked

4 citations

Venkat R. Chirasani, M. Ashhar I. Khan, Juilee N. Malavade, Nikolay V. Dokholyan, Brenton D. Hoffman +1 more

Septins Enable T Cell Contact Guidance via Amoeboid-Mesenchymal Switch

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.26.559597

N/A

0DataRank · unranked

2 citations

Alexis Manning, Chynna Smith, Jian Wang, Xuefei Ma, Denis Tsygankov +5 more

Differentiable Rotamer Sampling with Molecular Force Fields

arXiv (Cornell University)(2023)10.48550/arxiv.2302.11430

N/A

0DataRank · unranked

0 citations

Jian Wang, Nikolay V. Dokholyan, Congzhou M. Sha

Data from Modifications to the Framework Regions Eliminate Chimeric Antigen Receptor Tonic Signaling

(2023)10.1158/2326-6066.c.6550485

N/A

0DataRank · unranked

0 citations

Giovanni Fucà, Jian Wang, Venkat R. Chirasani, Zhiyuan Yao, Elena Dukhovlinova +14 more

Quantifying network behavior in the rat prefrontal cortex: a reproducibility crisis

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.16.541018

N/A

0DataRank · unranked

0 citations

Jian Wang, Richard B. Mailman, Yang Yang, Nikolay V. Dokholyan, Congzhou M. Sha

REAP-2: An interactive quantitative tool for robust and efficient dose-response curve estimation

Journal of Clinical and Translational Science(2023)10.1017/cts.2023.642

N/A

0DataRank · unranked

0 citations

Xinyi Liu, Vernon M. Chinchilli, Michael Wang, Honggang Wang, Nikolay V. Dokholyan +4 more

RNA-Puzzles Round V: blind predictions of 23 RNA structures

Nature Methods(2024)10.1038/s41592-024-02543-9

N/A

0DataRank · unranked

65 citations

Yagoub Adam, Ryszard W. Adamiak, Maciej Antczak, Belisa R. H. de Aquino, Nagendar Goud Badepally +94 more

Cracking the Code: Enhancing Molecular Tools for Progress in Nanobiotechnology

ACS Applied Bio Materials(2024)10.1021/acsabm.4c00432

N/A

0DataRank · unranked

8 citations

Laura P. Rebolledo, Elizabeth Skelly, Renata de Freitas Saito, Hui Wei, David M.J. Lilley +16 more

2′3′-cGAMP interactome identifies 2′3′-cGAMP/Rab18/FosB signaling in cell migration control independent of innate immunity

Science Advances(2024)10.1126/sciadv.ado7024

N/A

0DataRank · unranked

8 citations

Quentin Hahn, Le Yu, Zhichuan Zhu, Joshua A. Boyer, Jian Wang +18 more

Optogenetically engineered Septin-7 enhances immune cell infiltration of tumor spheroids

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2405717121

N/A

0DataRank · unranked

8 citations

Brianna Hnath, Congzhou M. Sha, Lynne Beidler, Todd D. Schell, Nikolay V. Dokholyan +1 more

Quantifying network behavior in the rat prefrontal cortex

Frontiers in Computational Neuroscience(2024)10.3389/fncom.2024.1293279

N/A

0DataRank · unranked

1 citations

Jian Wang, Richard B. Mailman, Yang Yang, Nikolay V. Dokholyan, Congzhou M. Sha

A Piecewise Design Approach to Engineering a Miniature ACE2 Mimic to Bind SARS-CoV-2

ACS Applied Bio Materials(2024)10.1021/acsabm.4c00222

N/A

0DataRank · unranked

3 citations

Brianna Hnath, Jian Wang, Morgan Chandler, Arnab Mukherjee, Neela H. Yennawar +4 more

Unveiling the double-edged sword: SOD1 trimers possess tissue-selective toxicity and bind septin-7 in motor neuron-like cells

Structure(2024)10.1016/j.str.2024.08.002

N/A

0DataRank · unranked

1 citations

Brianna Hnath, Congzhou M. Sha, Nikolay V. Dokholyan, Esther Choi

Allosteric inactivation of an engineered optogenetic GTPase

bioRxiv (Cold Spring Harbor Laboratory)10.1101/2022.05.16.490643

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Andrew L. Lee, Abha Jain

CANDI: A Web Server for Predicting Molecular Targets and Pathways of Cannabis-Based Therapeutics

Research Square(2024)10.21203/rs.3.rs-4744915/v1

N/A

0DataRank · unranked

1 citations

Jian Wang, Nikolay V. Dokholyan, E. Srinivasan

Unveiling the double-edged sword: SOD1 trimers possess tissue-selective toxicity and bind septin-7 in motor neuron-like cells

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.22.586186

N/A

0DataRank · unranked

0 citations

Brianna Hnath, Congzhou M. Sha, Nikolay V. Dokholyan, Esther Choi

APOE regulates the transport of GM1

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.02.587789

N/A

0DataRank · unranked

0 citations

Jian Wang, Gangtong Huang, Sara Langberg, Feng Ding, Nikolay V. Dokholyan +1 more

MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression

UNC Libraries(2024)10.17615/2v44-5k13

N/A

0DataRank · unranked

0 citations

Yixuan Zhang, Yufei Jiang, Peng Liu, Nikolay V. Dokholyan, Chunhai Fan +13 more

Peptide-based drug design using generative AI

Chemical Communications(2025)10.1039/d5cc04998a

N/A

0DataRank · unranked

18 citations

Nikolay V. Dokholyan, E. Srinivasan

Elevated intracellular copper induces CTR1 monomerization and prevents copper uptake

Nature Communications(2025)10.1038/s41467-025-66283-w

N/A

0DataRank · unranked

6 citations

Huanhuan Chen, Guangjie Yan, Yuteng Zhang, Wenkai Chen, Martin Dokholyan +4 more

Autonomous Nucleic Acid and Protein Nanocomputing Agents Engineered to Operate in Living Cells

ACS Nano(2025)10.1021/acsnano.4c13663

N/A

0DataRank · unranked

10 citations

Tanaya Basu Roy, Elizabeth Skelly, Morgan Chandler, Jian Wang, E. Srinivasan +4 more

The Evolving Landscape of Protein Allostery: From Computational and Experimental Perspectives

Journal of Molecular Biology(2025)10.1016/j.jmb.2025.169060

N/A

0DataRank · unranked

8 citations

Grigor Arakelov, Nikolay V. Dokholyan, E. Srinivasan

Apolipoprotein E (APOE) regulates the transport of monosialotetrahexosylganglioside (GM1)

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110778

N/A

0DataRank · unranked

4 citations

Jian Wang, Gangtong Huang, Martin Dokholyan, Smaranda Willcox, Jack D. Griffith +3 more

Nucleic acid nanobiosystems for cancer theranostics: an overview of emerging trends and challenges

Nanomedicine(2025)10.1080/17435889.2025.2501919

N/A

0DataRank · unranked

3 citations

Luciana Nogueira de Sousa Andrade, Marcio C. Bajgelman, Lawrence Banks, XANDRA O. BREAKEFIELD, Marina A. Dobrovolskaia +10 more

CANDI: a web server for predicting molecular targets and pathways of cannabis-based therapeutics

Journal of Cannabis Research(2025)10.1186/s42238-025-00268-w

N/A

0DataRank · unranked

1 citations

Jian Wang, Nikolay V. Dokholyan, E. Srinivasan

Optogenetic enzymes: A deep dive into design and impact

Current Opinion in Structural Biology(2025)10.1016/j.sbi.2025.103126

N/A

0DataRank · unranked

1 citations

Mana Heidari, Nikolay V. Dokholyan, Tanaya Basu Roy

Multimodal Bonds Reconstruction Towards Generative Molecular Design

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.06.652517

N/A

0DataRank · unranked

3 citations

Nikolay V. Dokholyan, Jian Wang

A Diffusion-Based Framework for Designing Molecules in Flexible Protein Pockets

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.27.656443

N/A

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2 citations

Dong Yan Zhang, Shreshty Budakoti, Nikolay V. Dokholyan, Jian Wang

Unified Protein-Small Molecule Graph Neural Networks for Binding Site Prediction

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.03.674017

N/A

0DataRank · unranked

1 citations

Nikolay V. Dokholyan, Jian Wang

Novel extracellular vesicle release pathway facilitated by toxic superoxide dismutase 1 oligomers

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.07.647611

N/A

0DataRank · unranked

0 citations

Nikolay V. Dokholyan, Brianna Hnath

Pilot wrap-around support initiative: Enhanced support for internally funded CTSA pilot awards

Journal of Clinical and Translational Science(2025)10.1017/cts.2025.10071

N/A

0DataRank · unranked

0 citations

Tyler J. Deal, John P. Vanden Heuvel, Aron E. Lukacher, Susan Mohammed, Nikolay V. Dokholyan +2 more

Trimeric superoxide dismutase 1 antibody as a universal biomarker for ALS

Research Square(2025)10.21203/rs.3.rs-6941118/v1

N/A

0DataRank · unranked

0 citations

Brianna Hnath, Rachel S. Dokholyan, Zachary Simmons, Nikolay V. Dokholyan

Targeting IL-1/IRAK1/4 signaling in acute myeloid leukemia stem cells following treatment and relapse

Leukemia(2025)10.1038/s41375-025-02816-y

N/A

0DataRank · unranked

0 citations

Mark W. LaMere, Hiroki Kawano, Daniel Byun, Elizabeth A. LaMere, Yu‐Chiao Chiu +12 more

Comprehensive mapping of the Interaction of levodopa and iron metabolism in Parkinson’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.13.612928

N/A

0DataRank · unranked

2 citations

E. Srinivasan, Xuemei Huang, Richard B. Mailman, Elizabeth A. Proctor, Nikolay V. Dokholyan +1 more

Mapping allosteric communications within individual proteins

Nature Communications(2020)10.1038/s41467-020-17618-2

N/A

0DataRank · unranked

206 citations

Abha Jain, Leanna R. McDonald, Craig W. Gambogi, Andrew L. Lee, Nikolay V. Dokholyan +1 more

RNA-Puzzles Round IV: 3D structure predictions of four ribozymes and two aptamers

RNA(2020)10.1261/rna.075341.120

N/A

0DataRank · unranked

173 citations

Ryszard W. Adamiak, Maciej Antczak, M. Boniecki, Janusz M. Bujnicki, Shi‐Jie Chen +45 more

Various miRNAs compensate the role of miR-122 on HCV replication

PLoS Pathogens(2020)10.1371/journal.ppat.1008308

N/A

0DataRank · unranked

17 citations

Takasuke Fukuhara, Songling Li, Jian Wang, Asuka Sato, Takuma Izumi +7 more

RNA-Puzzles: A CASP-like evaluation of RNA three-dimensional structure prediction

UNC Libraries(2020)10.17615/4xwy-qb25

N/A

0DataRank · unranked

19 citations

I. Tuszynska, J. Santalucia, Rhiju Das, F. Ding, P. Sripakdeevong +27 more

Physicochemical code for quinary protein interactions in Escherichia coli

UNC Libraries(2020)10.17615/etf3-g054

N/A

0DataRank · unranked

13 citations

David Mowray, Xin Mu, Seong Il Choi, Jens Danielsson, Nikolay V. Dokholyan +2 more

Expanding protein universe and its origin from the biological Big Bang

UNC Libraries(2020)10.17615/sskb-4g65

N/A

0DataRank · unranked

14 citations

Nikolay V. Dokholyan, Eugene I. Shakhnovich, B. Shakhnovich

Modifications of Superoxide Dismutase (SOD1) in Human Erythrocytes: A POSSIBLE ROLE IN AMYOTROPHIC LATERAL SCLEROSIS

UNC Libraries(2020)10.17615/2v0m-zj47

N/A

0DataRank · unranked

9 citations

Yanbao Yu, Li Zhou, Joshua K. Jordon, Nikolay V. Dokholyan, Kyle C. Wilcox +4 more

Experimentally-driven protein structure modeling

Journal of Proteomics(2020)10.1016/j.jprot.2020.103777

N/A

0DataRank · unranked

37 citations

Nikolay V. Dokholyan

Single-channel properties of skeletal muscle ryanodine receptor pore Δ4923FF4924 in two brothers with a lethal form of fetal akinesia

Cell Calcium(2020)10.1016/j.ceca.2020.102182

N/A

0DataRank · unranked

7 citations

Frederike L. Harms, Venkat R. Chirasani, Daniel A. Pasek, Fanny Kortüm, Peter Meinecke +4 more

Dynamical roles of metal ions and the disulfide bond in Cu, Zn superoxide dismutase folding and aggregation

UNC Libraries(2020)10.17615/986v-kc15

N/A

0DataRank · unranked

6 citations

Nikolay V. Dokholyan, F. Ding

Channel Gating Dependence on Pore Lining Helix Glycine Residues in Skeletal Muscle Ryanodine Receptor

UNC Libraries(2020)10.17615/b5f0-eb89

N/A

0DataRank · unranked

3 citations

Le Xu, Ying Wang, Nikolay V. Dokholyan, Daniel A. Pasek, David D. Mowrey +3 more

Potentiator ivacaftor abrogates pharmacological correction of F508 CFTR in cystic fibrosis

UNC Libraries(2020)10.17615/hrss-sw16

N/A

0DataRank · unranked

8 citations

D. M. Cholon, N. L. Quinney, R. C. Boucher, C. R. Esther, J. Das +4 more